Elevated plasma levels of neuropeptide proenkephalin a predict mortality and functional outcome in ischemic stroke

Journal of the American College of Cardiology

Volumn 60, Issue 4, 2012, Pages 346-354

  Doehner, Wolfram ^a   Von Haehling, Stephan ^a   Suhr, Jennifer ^b   Ebner, Nicole ^a   Schuster, Andreas ^c   Nagel, Eike ^c   Melms, Arthur ^d   Wurster, Thomas ^d   Stellos, Konstantinos ^e   Gawaz, Meinrad ^d   Bigalke, Boris ^c,d  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^b ICI immunochemical intelligence GmbH   (Germany)

^c KING'S COLLEGE LONDON   (United Kingdom)

^d UNIVERSITY OF TÜBINGEN   (Germany)

^e GOETHE UNIVERSITY   (Germany)

Author keywords

biomarker; blood brain barrier; proenkephalin; protachykinin; stroke

Indexed keywords

ACETYLSALICYLIC ACID; ANGIOTENSIN RECEPTOR ANTAGONIST; ANTIVITAMIN K; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; C REACTIVE PROTEIN; CLOPIDOGREL; CREATINE KINASE; CREATININE; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; GLUCOSE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; NEUROPEPTIDE; NEUROPEPTIDE PROENKEPHALIN A; PREPROTACHYKININ; UNCLASSIFIED DRUG;

AGE; AGED; ARTICLE; BRAIN DAMAGE; CLINICAL ASSESSMENT; COMPUTER ASSISTED TOMOGRAPHY; CORONARY ARTERY DISEASE; DIABETES MELLITUS; DISABILITY; DISEASE ASSOCIATION; DISEASE MARKER; DISEASE SEVERITY; ENZYME IMMUNOASSAY; FEMALE; FUNCTIONAL ASSESSMENT; HEART ATRIUM FIBRILLATION; HUMAN; HYPERLIPIDEMIA; HYPERTENSION; LIMIT OF DETECTION; MAJOR CLINICAL STUDY; MALE; MORTALITY; NATIONAL INSTITUTES OF HEALTH STROKE SCALE; OBSERVATIONAL STUDY; PREDICTION AND FORECASTING; PRIORITY JOURNAL; PROSPECTIVE STUDY; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; SMOKING; TRANSIENT ISCHEMIC ATTACK;

AGED; AGED, 80 AND OVER; BIOLOGICAL MARKERS; BRAIN DAMAGE, CHRONIC; BRAIN ISCHEMIA; CAUSE OF DEATH; CEREBRAL INFARCTION; DISABILITY EVALUATION; ENKEPHALINS; FEMALE; FOLLOW-UP STUDIES; HUMANS; INTRACRANIAL ARTERIOSCLEROSIS; ISCHEMIC ATTACK, TRANSIENT; MALE; MIDDLE AGED; PREDICTIVE VALUE OF TESTS; PROTEIN PRECURSORS; TACHYKININS;

EID: 84863948616     PISSN: 07351097     EISSN: 15583597     Source Type: Journal    
DOI: 10.1016/j.jacc.2012.04.024     Document Type: Article

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