The opioid systems - Panacea and nemesis

Biochemical and Biophysical Research Communications

Volumn 396, Issue 1, 2010, Pages 140-142

  Terenius, Lars ^a   Johansson, Björn ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

Author keywords

Drug dependence; Opioid peptides; Opioid receptors; Reward

Indexed keywords

ALCOHOL; BETA ENDORPHIN; DYNORPHIN A; DYNORPHIN B; ENDORPHIN; ENKEPHALIN; G PROTEIN COUPLED RECEPTOR; LEUCINE ENKEPHALIN; METENKEPHALIN; MORPHINE; MU OPIATE RECEPTOR; MU OPIATE RECEPTOR AGONIST; NALTREXONE; NEUROPEPTIDE; NOCICEPTIN RECEPTOR; OPIATE; PRODYNORPHIN; PROENKEPHALIN; PROOPIOMELANOCORTIN;

ALCOHOL ABUSE; ALCOHOLISM; ARTICLE; CENTRAL NERVOUS SYSTEM; COMPULSION; DRUG ABUSE; DRUG TARGETING; HUMAN; NOCICEPTION; NONHUMAN; PAIN; PRIORITY JOURNAL; PROTEIN FAMILY; RECEPTOR BLOCKING; REWARD;

ALLOSTASIS; ANALGESICS, OPIOID; ANIMALS; BEHAVIOR, ADDICTIVE; CONDITIONING, CLASSICAL; ENKEPHALINS; HUMANS; MICE; OPIOID PEPTIDES; OPIOID-RELATED DISORDERS; PRO-OPIOMELANOCORTIN; PROTEIN PRECURSORS; RATS; RECEPTORS, OPIOID, MU; REWARD;

EID: 77952301605     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2010.04.001     Document Type: Article

References (20)

1. Melzack R., and Wall P.D. Pain mechanisms: a new theory. Science 150 (1965) 971-979
2. Elde R., Hökfelt T., Johansson O., Terenius L., and Immunochemical L. Immunochemical studies using antibodies to leucine-enkephalin: initial observations on the nervous system of the rat. Neuroscience 1 (1976) 349-351
3. F.W. Sertürner, Darstellung der reinen Mohnsäure (Opiumsäure) nebst einer chemischen Untersuchung des Opiums mit vorzüglicher Hinsicht auf einen darin neu entdeckten Stoff und die dahin gehörigen Bemerkungen, Trommsdorffs Journal der Pharmacie, 14, Band, 1806.
4. O. Schaumann, Morphin und Morphinähnlich wirkende Verbindungen, In: O. Eichler, A. Farah (Eds.), Handbuch der Experimentellen Pharmakologie, Springer-Verlag, Berlin, Göttingen, Heidelberg, 1957.
5. Belluzzi J.D., and Stein L. Enkephalin may mediate euphoria and drive-reduction reward. Nature 266 (1977) 556-558
6. Roberts A.J., McDonald J.S., Heyser C.J., Kieffer B.L., Matthes H.W., Koob G.F., and Gold L.H. Mu-opioid receptor knockout mice do not self-administer alcohol. J. Pharmacol. Exp. Ther. 293 (2000) 1002-1008
7. Kovacs K.M., Szakall I., O'Brien D., Wang R., Vinod K.Y., Saito M., Simonin F., Kieffer B.L., and Vadasz C. Decreased oral self-administration of alcohol in kappa-opioid receptor knock-out mice. Alcohol Clin. Exp. Res. 29 (2005) 730-738
8. Dreborg S., Sundström G., Larsson T.A., and Larhammar D. Evolution of vertebrate opioid receptors. Proc. Natl. Acad. Sci. USA 105 (2008) 15487-15492
9. Olds J., and Milner P. Positive reinforcement produced by electrical stimulation of septal area and other regions of rat brain. J. Comp. Physiol. Psychol. 47 (1954) 419-427
10. Di Chiara G., and Bassareo V. Reward system and addiction: what dopamine does and doesn't do. Curr. Opin. Pharmacol. 7 (2007) 69-76
11. V. David, T.P. Durkin, P. Cazala, Differential effects of the dopamine D2/D3 receptor antagonist sulpiride on self-administration of morphine into the ventral tegmental area or the nucleus accumbens, Psychopharmacology (Berl.) 160 (2002) 307-317.
12. Ventura R., Alcaro A., and Puglisi-Allegra S. Prefrontal cortical norepinephrine release is critical for morphine-induced reward, reinstatement and dopamine release in the nucleus accumbens. Cereb. Cortex 15 (2005) 1877-1886
13. Koob G.F., and Le Moal M. Drug addiction, dysregulation of reward, and allostasis. Neuropsychopharmacology 24 (2001) 97-129
14. V.A. Redila, C. Chavkin. Stress-induced reinstatement of cocaine seeking is mediated by the kappa opioid system, Psychopharmacology (Berl.) 200 (2008) 59-70.
15. Walker B.M., and Koob G.F. Pharmacological evidence for a motivational role of kappa-opioid systems in ethanol dependence. Neuropsychopharmacology 33 (2008) 643-652
16. Kuzmin A., Sandin J., Terenius L., and Ögren S.O. Acquisition, expression, and reinstatement of ethanol-induced conditioned place preference in mice: effects of opioid receptor-like 1 receptor agonists and naloxone. J. Pharmacol. Exp. Ther. 304 (2003) 310-318
17. Koob G.F. A role for brain stress systems in addiction. Neuron 59 (2008) 11-34
18. Oslin D.W., Berrettini W., Kranzler H.R., Pettinati H., Gelernter J., Volpicelli J.R., and O'Brien C.P. A functional polymorphism of the mu-opioid receptor gene is associated with naltrexone response in alcohol-dependent patients. Neuropsychopharmacology 28 (2003) 1546-1552
19. Vukojevic V., Ming Y., D'Addario C., Hansen M., Langel U., Schulz R., Johansson B., Rigler R., and Terenius L. Mu-opioid receptor activation in live cells. FASEB J. 22 (2008) 3537-3548
20. Vukojevic V., Ming Y., D'Addario C., Rigler R., Johansson B., and Terenius L. Ethanol/naltrexone interactions at the mu-opioid receptor, CLSM/FCS study in live cells. PLoS ONE 3 (2008) e4008