CaMKII inhibition hyperpolarizes membrane and blocks nitrergic IJP by closing a Cl - conductance in intestinal smooth muscle

American Journal of Physiology - Gastrointestinal and Liver Physiology

Volumn 303, Issue 2, 2012, Pages

  He, Xue Dao ^a   Goyal, Raj K ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

Author keywords

Calmodulin dependent protein kinase II; Cromakalim; Electrotonic potential; Kn93; Niflumic acid; Tomita bath

Indexed keywords

CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE II; CHLORIDE CHANNEL; CROMAKALIM; N [2 [[N [3 (4 CHLOROPHENYL) 2 PROPENYL] N METHYLAMINO]METHYL]PHENYL] N (2 HYDROXYETHYL) 4 METHOXYBENZENESULFONAMIDE; NIFLUMIC ACID; POTASSIUM CHANNEL;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG MECHANISM; ELECTROSTIMULATION; ENZYME INHIBITION; FEMALE; HYPERPOLARIZATION; INHIBITORY JUNCTION POTENTIAL; INTESTINE MUSCLE; ION CONDUCTANCE; MALE; MEMBRANE CONDUCTANCE; MEMBRANE POTENTIAL; MICROELECTRODE; NEUROTRANSMISSION; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION;

ANIMALS; BENZYLAMINES; CALCIUM-CALMODULIN-DEPENDENT PROTEIN KINASE TYPE 2; CHLORIDE CHANNELS; CROMAKALIM; FEMALE; GUINEA PIGS; ILEUM; MALE; MEMBRANE POTENTIALS; MUSCLE, SMOOTH; NIFLUMIC ACID; NITRERGIC NEURONS; PROTEIN KINASE INHIBITORS; SULFONAMIDES;

EID: 84863938974     PISSN: 01931857     EISSN: 15221547     Source Type: Journal    
DOI: 10.1152/ajpgi.00102.2012     Document Type: Article

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