Decrease in salivary lactoferrin output in chronically intoxicated alcohol-dependent patients

Folia Histochemica et Cytobiologica

Volumn 50, Issue 2, 2012, Pages 248-254

  Waszkiewicz, Napoleon ^a   Zalewska Szajda, Beata ^a   Zalewska, Anna ^a   Waszkiewicz, Magdalena ^b   Szajda, Sławomir Dariusz ^a   Repka, Bernadeta ^c   Szulc, Agata ^a   Kepka, Alina ^d   Minarowska, Alina ^a   Chojnowska, Sylwia ^e   Konarzewska, Beata ^a   Ładny, Jerzy Robert ^a   Kowzan, Urszula ^a   Zwierz, Krzysztof ^c  

^a MEDICAL UNIVERSITY OF BIALYSTOK   (Poland)

^b Regional Hospital in Bialystok   (Poland)

^c Medical College of the Universal Education Society   (Poland)

^d CHILDREN'S MEMORIAL HEALTH INSTITUTE   (Poland)

^e Institute of Physical Education   (Poland)

Author keywords

Alcohol; Ethanol; Lactoferrin; Saliva

Indexed keywords

ALCOHOL; LACTOFERRIN;

ADULT; ALCOHOL CONSUMPTION; ALCOHOL INTOXICATION; ALCOHOLISM; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; MALE; SALIVA ANALYSIS; SALIVA LEVEL;

EID: 84863879759     PISSN: 02398508     EISSN: 18975631     Source Type: Journal    
DOI: 10.5603/FHC.2012.0024     Document Type: Article

References (46)

1. Waszkiewicz N, Konarzewska B, Waszkiewicz M et al. Biomarkers of alcohol abuse. Part I. Traditional biomarkers and their interpretation. Psychiatr Pol. 2010;44:127-136.
2. World Health Organization. Global Status Report on Alcohol. 2011 Geneva, Switzerland.
3. Waszkiewicz N, Szulc A. Diagnosis of alcohol abuse. Przegl Lek. 2009;66:529-534.
4. Waszkiewicz N, Zalewska A, Szulc A et al. The influence of alcohol on the oral cavity, salivary glands and saliva. Pol Merkur Lekarski. 2011;30:69-74.
5. Waszkiewicz N, Szajda SD, Kepka A, Szulc A, Zwierz K. Glycoconjugates in the detection of alcohol abuse. Biochem Soc Trans. 2011;39:365-369.
6. Waszkiewicz N, Szajda SD, Zalewska A et al. Alcohol abuse and glycoconjugate metabolism. Folia Histochem Cytobiol. 2012;50:1-11.
7. Waszkiewicz N, Szajda SD, Jankowska A et al. The effect of acute ethanol intoxication on salivary proteins of innate and adaptive immunity. Alcohol Clin Exp Res. 2008;32:652-656.
8. Waszkiewicz N, Zalewska A, Szajda SD et al. The effect of chronic alcohol intoxication and smoking on the output of salivary immunoglobulin A. Folia Histochem Cytobiol. 2012; (in press).
9. Waszkiewicz N, Zalewska A, Szajda SD et al. The effect of chronic alcohol intoxication and smoking on the activity of oral peroxidase. Folia Histochem Cytobiol. 2012; (in press).
10. Waszkiewicz N, Poplawska R, Konarzewska B et al. Biomarkers of alcohol abuse. Part II. New biomarkers and their interpretation. Psychiatr Pol. 2010;44:137-146.
11. Waszkiewicz N, Szulc A. Immunity defects in acute and chronic alcohol intoxication. Pol Merkur Lekarski. 2010;172:269-273.
12. Waszkiewicz N, Szajda SD, Konarzewska B, Szulc A, Kepka A, Zwierz K. Underappreciated role of binge drinking in the risk of lung cancer. Eur J Public Health. 2010;20:6.
13. Farnaud S, Evans RW. Lactoferrin - a multifunctional protein with antimicrobial properties. Mol Immunol. 2003;40: 395-405.
14. Thome J, Foley P, Gsell W et al. Increased concentrations of manganese superoxide dismutase in serum of alcohol-dependent patients. Alcohol Alcohol. 1997;32:65-69.
15. Klebanoff SJ, Waltersdorph AM. Prooxidant activity of transferrin and lactoferrin. J Exp Med. 1990;172:1293-1303.
16. Almstahl A, Wikstrom M, Groenink J. Lactoferrin, amylase and mucin MUC5B and their relation to the oral microflora in hyposalivation of different origins. Oral Microbiol Immunol. 2001;16:345-352.
17. de Almeida Pdel V, Gregio AM, Machado MA, de Lima AA, Azevedo LR. Saliva composition and functions: a comprehensive review. J Contemp Dent Pract. 2008;9:72-80.
18. Jankowska AK, Waszkiel D, Kobus A, Zwierz K. Ślina jako główny składnik ekosystemu jamy ustnej. Cze{ogonek}ść II. Mechanizmy odpornościowe. Wiad Lek. 2007;60:253-257.
19. Brock J. Lactoferrin: a multifunctional immunoregulatory protein? Immunol Today. 1995;16:417-419.
20. Rudney JD. Does variability in salivary protein concentrations influence oral microbial ecology and oral health? Crit Rev Oral Biol Med. 1995;6:343-367.
21. Amerongen AV, Veerman EC. Saliva - the defender of the oral cavity. Oral Dis. 2002;8:12-22.
22. Nilsson E, Hallden G, Magnusson KE, Hed J, Palmblad J. In vitro effects of ethanol on polymorphonuclear leukocyte membrane receptor expression and mobility. Biochem Pharmacol. 1996;51:225-231.
23. Loe H, Silness J. Periodontal disease in pregnancy. I. Prevalence and severity. Acta Odontol Scand. 1963;21:533-551.
24. Saxer UP, Muhlemann HR. Motivation and education. SSO Schweiz Monatsschr Zahnheilkd. 1975;85:905-919.
25. Dawes C. Physiological factors affecting salivary flow rate, oral sugar clearance, and the sensation of dry mouth in man. J Dent Res. 1987;66:648-653.
26. Navazesh M, Christensen C, Brightman V. Clinical criteria for the diagnosis of salivary gland hypofunction. J Dent Res. 1992;71:1363-1369.
27. Riedel F, Goessler U, Hormann K. Alcohol-related diseases of the mouth and throat. Best Pract Res Clin Gastroenterol. 2003;17:543-555.
28. Slomiany BL, Piotrowski J, Slomiany A. Chronic alcohol ingestion enhances tumor necrosis factor-alpha expression and salivary gland apoptosis. Alcohol Clin Exp Res. 1997;21:1530-1533.
29. Tanida T, Okamoto T, Okamoto A et al. Decreased excretion of antimicrobial proteins and peptides in saliva of patients with oral candidiasis. J Oral Pathol Med. 2003;32: 586-594.
30. Muller P, Hepke B, Meldau U, Raabe G. Tissue damage in the rabbit oral mucosa by acute and chronic direct toxic action of different alcohol concentrations. Exp Pathol. 1983;24:171-181.
31. Knoll MR, Kolbel CB, Teyssen S, Singer MV. Action of pure ethanol and some alcoholic beverages on the gastric mucosa in healthy humans: a descriptive endoscopic study. Endoscopy. 1998;30:293-301.
32. Fitzgerald DJ, Radek KA, Chaar M, Faunce DE, DiPietro LA, Kovacs EJ. Effects of acute ethanol exposure on the early inflammatory response after excisional injury. Alcohol Clin Exp Res. 2007;31:317-323.
33. Nelson S, Kolls JK. Alcohol, host defense and society. Nat Rev Immunol. 2002;2:205-209.
34. Goral J, Karavitis J, Kovacs EJ. Exposure-dependent effects of ethanol on the innate immune system. Alcohol. 2008;42:237-247.
35. Maier H, Born IA, Veith S, Adler D, Seitz HK. The effect of chronic ethanol consumption on salivary gland morphology and function in the rat. Alcohol Clin Exp Res. 1986;10: 425-427.
36. Dutta SK, Orestes M, Vengulekur S, Kwo P. Ethanol and human saliva: effect of chronic alcoholism on flow rate, composition, and epidermal growth factor. Am J Gastroenterol. 1992;87:350-354.
37. Ryder MI. The influence of smoking on host responses in periodontal infections. Periodontol 2000. 2007;43:267-277.
38. Scott J, Burns J, Flower EA. Histological analysis of parotid and submandibular glands in chronic alcohol abuse: a necropsy study. J Clin Pathol. 1988;41:837-840.
39. Smith PF, Ramirez JC, Romo RE, Esguep AS. Salivary glands in alcoholism: a histologic and sialographic study. Addict Biol. 1996;1:385-393.
40. De Witte P, Pinto E, Ansseau M, Verbanck P. Alcohol and withdrawal: from animal research to clinical issues. Neurosci Biobehav Rev. 2003;27:189-197.
41. Karolewska E, Konopka T, Pupek M, Chybicka A, Mendak M. Antibacterial potential of saliva in children with leukemia. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2008;105:739-744.
42. Keedwell PA, Poon L, Papadopoulos AS, Marshall EJ, Checkley SA. Salivary cortisol measurements during a medically assisted alcohol withdrawal. Addict Biol. 2001;6:247-256.
43. Homann N, Tillonen J, Meurman JH et al. Increased salivary acetaldehyde levels in heavy drinkers and smokers: a microbiological approach to oral cavity cancer. Carcinogenesis. 2000;21:663-668.
44. Khocht A, Schleifer SJ, Janal MN, Keller S. Dental care and oral disease in alcohol dependent persons. J Subst Abuse Treat. 2009;2:214-218.
45. Kobus A, Szajda SD, Kierklo A et al. Oral status in smoking and nonsmoking alcohol abusing patients. Polish J Environ Stud. 2008;17:306-310.
46. Slomiany BL, Liau YH, Zalesna G, Slomiany A. Effect of ethanol on the in vitro sulfation of salivary mucin. Alcohol Clin Exp Res. 1988;12:774-779.