Expression and roles of MMP-2, MMP-9, MMP-13, TIMP-1, and TIMP-2 in allergic nasal mucosa

Allergy, Asthma and Immunology Research

Volumn 4, Issue 4, 2012, Pages 231-239

  Mori, Sachiko ^a   Pawankar, Ruby ^a   Ozu, Chika ^a   Nonaka, Manabu ^a   Yagi, Toshiaki ^a   Okubo, Kimihiro ^a  

^a NIPPON MEDICAL SCHOOL   (Japan)

Author keywords

Allergic rhinitis; Cell infiltration; Eosinophils; Mast cells; Mmp; Timp

Indexed keywords

COLLAGENASE 3; GELATINASE A; GELATINASE B; HOUSE DUST ALLERGEN; TISSUE INHIBITOR OF METALLOPROTEINASE 1; TISSUE INHIBITOR OF METALLOPROTEINASE 2;

ADOLESCENT; ADULT; AGED; ARTICLE; CHILD; CLINICAL ARTICLE; COMPARATIVE STUDY; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; EOSINOPHIL; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MALE; MAST CELL; NOSE ALLERGY; NOSE MUCOSA; PRESCHOOL CHILD; QUANTITATIVE ANALYSIS; SCHOOL CHILD;

EID: 84863878817     PISSN: 20927355     EISSN: 20927363     Source Type: Journal    
DOI: 10.4168/aair.2012.4.4.231     Document Type: Article

References (30)

1. Howarth PH. ABC of allergies. Pathogenic mechanisms: a rational basis for treatment. BMJ 1998;316:758-61.
2. Howarth PH, Salagean M, Dokic D. Allergic rhinitis: not purely a histamine-related disease. Allergy 2000;55 Suppl 64:7-16.
3. Pawankar R. Allergic rhinitis and asthma: are they manifestations of one syndrome? Clin Exp Allergy 2006;36:1-4.
4. Djukanović R, Wilson SJ, Howarth PH. Pathology of rhinitis and bronchial asthma. Clin Exp Allergy 1996;26 Suppl 3:44-51.
5. Mygind N, Bisgaard H. Applied anatomy of the airways. In: Mygind N, Pipkorn U, Dahl R, editors. Rhinitis and asthma: similarities and differences. Copenhagen: Munksgaard; 1990. 21-37.
6. Busse WW, Holgate ST, editors. Asthma and rhinitis. Boston: Blackwell Scientific Publications; 1995. 12-624.
7. Lee KS, Jin SM, Kim HJ, Lee YC. Matrix metalloproteinase inhibitor regulates inflammatory cell migration by reducing ICAM-1 and VCAM-1 expression in a murine model of toluene diisocyanate-induced asthma. J Allergy Clin Immunol 2003;111:1278-84.
8. Hoshino M, Nakamura Y, Sim J, Shimojo J, Isogai S. Bronchial subepithelial fibrosis and expression of matrix metalloproteinase-9 in asthmatic airway inflammation. J Allergy Clin Immunol 1998;102:783-8.
9. Murphy G, Docherty AJ. The matrix metalloproteinases and their inhibitors. Am J Respir Cell Mol Biol 1992;7:120-5.
10. Nagase H. Activation mechanisms of matrix metalloproteinases. Biol Chem 1997;378:151-60.
11. Howarth PH. The cellular basis for allergic rhinitis. Allergy 1995;50:6-10.
12. Salib RJ, Howarth PH. Remodelling of the upper airways in allergic rhinitis: is it a feature of the disease? Clin Exp Allergy 2003;33:1629-33.
13. Shimizu T, Kanai K, Asano K, Hisamitsu T, Suzaki H. Suppression of matrix metalloproteinase production in nasal fibroblasts by tranilast, an antiallergic agent, in vitro. Mediators Inflamm 2005;2005:150-9.
14. Hoshino M, Takahashi M, Takai Y, Sim J. Inhaled corticosteroids decrease subepithelial collagen deposition by modulation of the balance between matrix metalloproteinase-9 and tissue inhibitor of metalloproteinase-1 expression in asthma. J Allergy Clin Immunol 1999;104:356-63.
15. Ohno I, Ohtani H, Nitta Y, Suzuki J, Hoshi H, Honma M, Isoyama S, Tanno Y, Tamura G, Yamauchi K, Nagura H, Shirato K. Eosinophils as a source of matrix metalloproteinase-9 in asthmatic airway inflammation. Am J Respir Cell Mol Biol 1997;16:212-9.
16. Kanbe N, Tanaka A, Kanbe M, Itakura A, Kurosawa M, Matsuda H. Human mast cells produce matrix metalloproteinase 9. Eur J Immunol 1999;29:2645-9.
17. Fang KC, Wolters PJ, Steinhoff M, Bidgol A, Blount JL, Caughey GH. Mast cell expression of gelatinases A and B is regulated by kit ligand and TGF-beta. J Immunol 1999;162:5528-35.
18. Vignola AM, Chiappara G, Chanez P, Merendino AM, Pace E, Spatafora M, Bousquet J, Bonsignore G. Growth factors in asthma. Monaldi Arch Chest Dis 1997;52:159-69.
19. Roche WR, Beasley R, Williams JH, Holgate ST. Subepithelial fibrosis in the bronchi of asthmatics. Lancet 1989;1:520-4.
20. Chakir J, Laviolette M, Boutet M, Laliberté R, Dubé J, Boulet LP. Lower airways remodeling in nonasthmatic subjects with allergic rhinitis. Lab Invest 1996;75:735-44.
21. Bousquet J, Jacot W, Vignola AM, Bachert C, Van Cauwenberge P. Allergic rhinitis: a disease remodeling the upper airways? J Allergy Clin Immunol 2004;113:43-9.
22. Pawankar R, Watanabe S, Nonaka M, Ozu C, Aida M, Yagi T. Differential expression of matrix metalloproteinase 2 and 9 in the allergic nasal mucosa and nasal polyps. J Allergy Clin Immunol 2004;113:S332.
23. Calderón MA, Lozewicz S, Prior A, Jordan S, Trigg CJ, Davies RJ. Lymphocyte infiltration and thickness of the nasal mucous membrane in perennial and seasonal allergic rhinitis. J Allergy Clin Immunol 1994;93:635-43.
24. Pawankar R. Inflammatory mechanisms in allergic rhinitis. Curr Opin Allergy Clin Immunol 2007;7:1-4.
25. Shaida A, Kenyon G, Devalia J, Davies RJ, MacDonald TT, Pender SL. Matrix metalloproteinases and their inhibitors in the nasal mucosa of patients with perennial allergic rhinitis. J Allergy Clin Immunol 2001;108:791-6.
26. Herouy Y, Mellios P, Bandemir E, Dichmann S, Nockowski P, Schöpf E, Norgauer J. Inflammation in stasis dermatitis upregulates MMP-1, MMP-2 and MMP-13 expression. J Dermatol Sci 2001;25:198-205.
27. Dahlen B, Shute J, Howarth P. Immunohistochemical localisation of the matrix metalloproteinases MMP-3 and MMP-9 within the airways in asthma. Thorax 1999;54:590-6.
28. Shin HW, Han DH, Lim YS, Kim HJ, Kim DY, Lee CH, Min YG, Rhee CS. Nonasthmatic nasal polyposis patients with allergy exhibit greater epithelial MMP positivity. Otolaryngol Head Neck Surg 2009;141:442-7.
29. Moon IJ, Kim DY, Rhee CS, Lee CH, Min YG. Role of angiogenic factors in airway remodeling in an allergic rhinitis murine model. Allergy Asthma Immunol Res 2012;4:37-45.
30. Erlewyn-Lajeunesse MD, Hunt LP, Pohunek P, Dobson SJ, Kochhar P, Warner JA, Warner JO. Bronchoalveolar lavage MMP-9 and TIMP-1 in preschool wheezers and their relationship to persistent wheeze. Pediatr Res 2008;64:194-9.