Effectiveness of same versus mixed asthma inhaler devices: A retrospective observational study in primary care

Allergy, Asthma and Immunology Research

Volumn 4, Issue 4, 2012, Pages 184-191

  Price, David ^a,b   Chrystyn, Henry ^c   Kaplan, Alan ^d   Haughney, John ^a   Román Rodríguez, Miguel ^e   Burden, Annie ^b   Chisholm, Alison ^b   Hillyer, Elizabeth V ^b   von Ziegenweidt, Julie ^b   Ali, Muzammil ^b   van der Molen, Thys ^f  

^a UNIVERSITY OF ABERDEEN   (United Kingdom)

^b Research in Real Life Ltd   (United Kingdom)

^c UNIVERSITY OF HUDDERSFIELD   (United Kingdom)

^d Family Physician Airways Group of Canada   (Canada)

^e Son Pisa Primary Health Care Centre   (Spain)

^f UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

Author keywords

Asthma; Breath actuated inhaler; Inhaled corticosteroids; Inhaler device; Pressurised metered dose inhaler; Short acting 2 agonist

Indexed keywords

ANTIBIOTIC AGENT; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CORTICOSTEROID; NONSTEROID ANTIINFLAMMATORY AGENT; PARACETAMOL; SALBUTAMOL;

ADOLESCENT; ADULT; AGED; ARTICLE; ASTHMA; CHILD; COMPARATIVE STUDY; FEMALE; HOSPITALIZATION; HUMAN; INHALER; LOWER RESPIRATORY TRACT INFECTION; MAJOR CLINICAL STUDY; MALE; OBSERVATIONAL STUDY; PRESCHOOL CHILD; PRIMARY MEDICAL CARE; RETROSPECTIVE STUDY; SCHOOL CHILD; TREATMENT OUTCOME;

EID: 84863870165     PISSN: 20927355     EISSN: 20927363     Source Type: Journal    
DOI: 10.4168/aair.2012.4.4.184     Document Type: Article

References (26)

1. Melani AS, Bonavia M, Cilenti V, Cinti C, Lodi M, Martucci P, Serra M, Scichilone N, Sestini P, Aliani M, Neri M; Gruppo Educazionale Associazione Italiana Pneumologi Ospedalieri. Inhaler mishandling remains common in real life and is associated with reduced disease control. Respir Med 2011;105:930-8.
2. Molimard M, Raherison C, Lignot S, Depont F, Abouelfath A, Moore N. Assessment of handling of inhaler devices in real life: an observational study in 3811 patients in primary care. J Aerosol Med 2003; 16:249-54.
3. Sestini P, Cappiello V, Aliani M, Martucci P, Sena A, Vaghi A, Canessa PA, Neri M, Melani AS; Associazione Italiana Pneumologi Ospedalieri Educational Group. Prescription bias and factors associated with improper use of inhalers. J Aerosol Med 2006;19:127-36.
4. Hardwell A, Barber V, Hargadon T, McKnight E, Holmes J, Levy ML. Technique training does not improve the ability of most patients to use pressurised metered-dose inhalers (pMDIs). Prim Care Respir J 2011;20:92-6.
5. Giraud V, Roche N. Misuse of corticosteroid metered-dose inhaler is associated with decreased asthma stability. Eur Respir J 2002;19: 246-51.
6. Chrystyn H, Price D. Not all asthma inhalers are the same: factors to consider when prescribing an inhaler. Prim Care Respir J 2009; 18:243-9.
7. Broeders ME, Sanchis J, Levy ML, Crompton GK, Dekhuijzen PN; ADMIT Working Group. The ADMIT series-issues in inhalation therapy. 2. Improving technique and clinical effectiveness. Prim Care Respir J 2009;18:76-82.
8. Virchow JC, Crompton GK, Dal Negro R, Pedersen S, Magnan A, Seidenberg J, Barnes PJ. Importance of inhaler devices in the management of airway disease. Respir Med 2008;102:10-9.
9. Haughney J, Price D, Barnes NC, Virchow JC, Roche N, Chrystyn H. Choosing inhaler devices for people with asthma: current knowledge and outstanding research needs. Respir Med 2010;104:1237-45.
10. Dolovich MB, Ahrens RC, Hess DR, Anderson P, Dhand R, Rau JL, Smaldone GC, Guyatt G; American College of Chest Physicians; American College of Asthma, Allergy, and Immunology. Device selection and outcomes of aerosol therapy: Evidence-based guidelines: American College of Chest Physicians/American College of Asthma, Allergy, and Immunology. Chest 2005;127:335-71.
11. Haughney J, Price D, Kaplan A, Chrystyn H, Horne R, May N, Moffat M, Versnel J, Shanahan ER, Hillyer EV, Tunsäter A, Bjermer L. Achieving asthma control in practice: understanding the reasons for poor control. Respir Med 2008;102:1681-93.
12. van der Palen J, Klein JJ, van Herwaarden CL, Zielhuis GA, Seydel ER. Multiple inhalers confuse asthma patients. Eur Respir J 1999; 14:1034-7.
13. General Practice Research Database. The Medicines and Healthcare Products Regulatory Agency [Internet]. London; [cited 2011 Oct 25]. Available from: http://www.gprd.com/.
14. Walley T, Mantgani A. The UK General Practice Research Database. Lancet 1997;350:1097-9.
15. Hansell A, Hollowell J, Nichols T, McNiece R, Strachan D. Use of the General Practice Research Database (GPRD) for respiratory epidemiology: a comparison with the 4th Morbidity Survey in General Practice (MSGP4). Thorax 1999;54:413-9.
16. Petersen I, Johnson AM, Islam A, Duckworth G, Livermore DM, Hayward AC. Protective effect of antibiotics against serious complications of common respiratory tract infections: retrospective cohort study with the UK General Practice Research Database. BMJ 2007;335:982.
17. Thomas M, von Ziegenweidt J, Lee AJ, Price D. High-dose inhaled corticosteroids versus add-on long-acting beta-agonists in asthma: an observational study. J Allergy Clin Immunol 2009;123:116-21.e10.
18. Price D, Martin RJ, Barnes N, Dorinsky P, Israel E, Roche N, Chisholm A, Hillyer EV, Kemp L, Lee AJ, von Ziegenweidt J, Colice G. Prescribing practices and asthma control with hydrofluoroalkane-beclomethasone and fluticasone: a real-world observational study. J Allergy Clin Immunol 2010;126:511-8.e1-10.
19. Reddel HK, Taylor DR, Bateman ED, Boulet LP, Boushey HA, Busse WW, Casale TB, Chanez P, Enright PL, Gibson PG, de Jongste JC, Kerstjens HA, Lazarus SC, Levy ML, O'Byrne PM, Partridge MR, Pavord ID, Sears MR, Sterk PJ, Stoloff SW, Sullivan SD, Szefler SJ, Thomas MD, Wenzel SE; American Thoracic Society/European Respiratory Society Task Force on Asthma Control and Exacerbations. An official American Thoracic Society/European Respiratory Society statement: asthma control and exacerbations: standardizing endpoints for clinical asthma trials and clinical practice. Am J Respir Crit Care Med 2009;180:59-99.
20. Research in Real Life: Standard Operating Procedures [Internet]. [cited 2011 Dec 17]. Available from: http://www.optimumpatientcare.org/Docs/SOP%20Observational%20Database%20Studies.pdf.
21. Dekhuijzen PN, Magnan A, Kneussl M; ADMIT Working Group. The ADMIT series - issues in inhalation therapy. 1) The goals of asthma treatment: can they be achieved? Prim Care Respir J 2007; 16:341-8.
22. Papi A, Haughney J, Virchow JC, Roche N, Palkonen S, Price D. Inhaler devices for asthma: a call for action in a neglected field. Eur Respir J 2011;37:982-5.
23. Thomas M, Price D, Chrystyn H, Lloyd A, Williams AE, von Ziegenweidt J. Inhaled corticosteroids for asthma: impact of practice level device switching on asthma control. BMC Pulm Med 2009;9:1.
24. Kozyrskyj AL, Dahl ME, Ungar WJ, Becker AB, Law BJ. Antibiotic treatment of wheezing in children with asthma: what is the practice? Pediatrics 2006;117:e1104-10.
25. Vanderweil SG, Tsai CL, Pelletier AJ, Espinola JA, Sullivan AF, Blumenthal D, Camargo CA Jr. Inappropriate use of antibiotics for acute asthma in United States emergency departments. Acad Emerg Med 2008;15:736-43.
26. Tannen RL, Weiner MG, Xie D. Use of primary care electronic medical record database in drug efficacy research on cardiovascular outcomes: comparison of database and randomised controlled trial findings. BMJ 2009;338:b81.