The ADMIT series - Issues in inhalation therapy. 2) Improving technique and clinical effectiveness

Primary Care Respiratory Journal

Volumn 18, Issue 2, 2009, Pages 76-82

  Broeders, Mariëlle E A C ^a   Sanchis, Joaquin ^b   Levy, Mark L ^d   Crompton, Graham K ^c   Dekhuijzen, P N Richard ^a  

^a RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^b UNIVERSITAT AUTÒNOMA DE BARCELONA   (Spain)

^c WESTERN GENERAL HOSPITAL   (United Kingdom)

^d UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

Aerosol therapy; Dry powder inhalers; Inhalation technique; Inhalers; pMDI

Indexed keywords

BECLOMETASONE DIPROPIONATE; BRONCHODILATING AGENT; CROMOGLYCATE DISODIUM; RESPIRATORY TRACT AGENT; SALBUTAMOL;

AEROSOL; ASTHMA; CHRONIC OBSTRUCTIVE LUNG DISEASE; CLINICAL EFFECTIVENESS; DISEASE EXACERBATION; DRUG BIOAVAILABILITY; DRUG DELIVERY SYSTEM; FOLLOW UP; HUMAN; INHALATION SPACER; METERED DOSE INHALER; NEBULIZER; OBSTRUCTIVE AIRWAY DISEASE; PATIENT EDUCATION; POWDER INHALER; REVIEW;

EID: 66549103085     PISSN: 14714418     EISSN: 14751534     Source Type: Journal    
DOI: 10.4104/pcrj.2009.00025     Document Type: Review

References (48)

1. Larsson S, Svedmyr N. Bronchodilating effect and side effects of Beta 2 -adrenoceptor stimulants by differen modes of administration (tablets, Metered Aerosol, and combinations thereof). Am Rev Respir Dis 1977;116: 861-869
2. Toogood JH, Baskerville J, Jennings B, Lefcoe NM, Johansson JA. Bioequivalent doses of budesnide and prednisone in moderate and severe asthma. J Allergy Clin Immunol 1989;84:688-700. http://dx.doi.org/10.1016/0091-6749(89) 90297-90302 (Pubitemid 20008500)
3. Lipworth BJ. Systemic adverse effects of inhaled corticosteroid therapy. A systematic review and meta-analysis. Arch Intern Med 1999;159:941-955 http://dx.doi.org/10.1001/archinte.159.9.941 (Pubitemid 29222495)
4. Dekhuijzen PN, Magnan A, Kneussl M on behalf of the ADMIT Working Group. The ADMIT series - issues in inhalation therapy. 1) The goals of asthma treatment: can they be achieved? Prim Care Resp J 2007;16(6):341-348 http://dx.doi.org/10.3132/pcrj.2007.00081
5. Cochrane MG, Bala MV, Downs KE, Mauskopf J and Ben-Joseph RH. Inhaled corticosteroids for asthma therapy. Patient compliance, devices and inhalation technique. Chest 2000;117:542-550 http://dx.doi.org/10.1378/chest.117.2.542 (Pubitemid 30111609)
6. Hesselink AE, Penninx BW, Wijnhoven HA, Kriegsman DM, van Eijk JT. Determinants of an incorrect inhalation technique in patients with asthma or COPD. Scand J Prim Health Care 2001;19:255-260 http://dx.doi.org/10.1080/ 02813430152706792 (Pubitemid 34032753)
7. van Beerendonk I, Mesters I, Mudde AN, Tan TD. Assessment of the inhalation technique in outpatients with asthma or chronic obstructive pulmonary disease using a metered-dose inhaler or dry powder device. J Asthma 1998;35:273-279 http://dx.doi.org/10.3109/02770909809068218 (Pubitemid 28379559)
8. Newman SP. Inhaler treatment options in COPD. Eur Respir Rev 2005;14:102-108 (Pubitemid 43028767)
9. Brocklebank D, Ram F, Wright J et al. Comparison of the effectiveness of inhaler devices in asthma and chronic obstructive airway disease: a systematic review of the literature. Health Technol Assess 2001;5:1-149.
10. Dolovich MB, Ahrens RC, Hess DR, et al. Device selection and outcomes of aerosol therapy: Evidence-based Guidelines. ACCP/ACAAI. Chest 2005;127: 335-371 http://dx.doi.org/10.1378/chest.127.1.335
11. Crompton GK. Problems patients have using pressurised aerosol inhalers. Eur J Respir Dis 1982;63(Suppl 119):101-104 (Pubitemid 12060363)
12. Chen SH, Yin TJ, Huang JL. An exploration of the skills needed for inhalation therapy in schoolchildren with asthma in Taiwan. Ann Allergy Asthma Immunol 2002;89:311-315 (Pubitemid 36188032)
13. Giraud V, Roche N. Misuse of corticosteroid mertered-dose inhaler is associated with decreased asthma stability. Eur Respir J 2002;19:246-251 http://dx.doi.org/10.1183/09031936.02.00218402 (Pubitemid 34162824)
14. Gabrio BJ, Stein SW, Velasquez DJ. A new method to evaluate plume characteristics of hydrofluoroalkane and chlorofluorocarbon metered dose inhalers. Int J Pherm 1999;186(1):3-12. http://dx.doi.org/10.1016/S0378-5173(99) 00133-137 (Pubitemid 29397518)
15. Orehek J, Gayrard P, Grimaud Ch, Charpin J. Patient error in use of bronchodilator metered aerosols. BMJ 1976;1:76. doi:10.1136/bmj.1.6001.76
16. Paterson IC, Crompton GK Use of pressurised aerosols by asthmatic patients. BMJ 1976;1:76-77. http://dx.doi.org/10.1136/bmj.1.6001.76-a
17. Gayrard P, Orehek L. Mauvaise utilisation des aerosols-doseurs par les asthmatiques. Respiration 1980;40:47-52. http://dx.doi.org/10.1159/000194250 (Pubitemid 10053791)
18. Lenney J, Innes JA, Crompton GK. Inappropriate inhaler use: assessment of use and patient preference of seven inhalation devices. Respir Med 2000;94:496-500. http://dx.doi.org/0.1053/rmed.1999.0767 (Pubitemid 30353008)
19. Melchor R, Biddiscombe MF, Mak VHF, Spiro SG. Lung deposition patterns of directly labelled salbutamol in normal subjects and in patients with reversible airflow obstruction. Thorax 1993;48:506-511 http://dx.doi.org/10.1136/thx.48.5. 506 (Pubitemid 23160166)
20. Lipworth Bj. New perspectives on inhaled drug delivery and systemic bioactivity. Thorax 1995;50:105-110 http://dx.doi.org/10.1136/thx.50.2.105
21. Barry PW, O'Callaghan C. In vitro comparison of the amount of salbutamol available for inhalation from different formulations used with different spacer devices. Eur Respir J 1997;10:1345-1348 http://dx.doi.org/10.1183/09031936.97. 10061345 (Pubitemid 27278258)
22. Mitchell JP, Nagel MW. Valved holding chambers (VHCs) for use with pressurised metered-dose inhalers (pMDIs): a review of causes of inconsistent medication delivery. Prim Care Resp J 2007;16:207-214. http://dx.doi.org/10. 3132/ pcrj.2007.00034 (Pubitemid 47281445)
23. Fink JB. Metered-dose inhalers, dry powder inhalers, and transitions. Respir Care 2000;45:623-635 (Pubitemid 30484802)
24. The Global Initiative on Asthma Global Strategy for Asthma Management and Prevention NHLBI/WHO Workshop Report. 2006 update. Available from : http://www.ginasthma.com
25. Global Initiative for chronic obstructive lung disease. Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease. Updated 2005 (Based on an April 1998 NHLBI/WHO Workshop).
26. Newman SP, Weisz AW, Talaee N, Clarke SW. Improvement of drug delivery with a breath actuated pressurised aerosol for patients with poor inhaler technique. Thorax 1991;46:712-716 http://dx.doi.org/10.1136/thx.46.10.712
27. Fergusson RJ, Lenney J, McHardy GJR, Crompton GK. The use of a new breathactuated inhaler by patients with severe airflow obstruction. Eur Respir J 1991; 4:172-174
28. Donnell D. Inhaler corticosteroid delivery systems: clinical role of a breathactuated device. Eur Rev Med Pharmacol Sci 2001;5:7-16. (Pubitemid 34177147)
29. Bell JH, Hartley PS, Cox JS. Dry powder aerosols. I. A new powder inhalation device. J Pharm Sci 1971;60:1559-1564 http://dx.doi.org/10.1002/jps. 2600601028
30. Hallworth GW. An improved design of powder inhaler. Br J Clin Pharmacol 1977;4:689-690 (Pubitemid 8231666)
31. Wetterlin K. Turbuhaler: A new powder inhaler for administration of drugs to the airways. Pharm Res 1988;5:506-08. http://dx.doi.org/10.1023/A: 1015969324799
32. Pover GM, Langdon CG, Jones SR, Fidler C. Evaluation of a Breath Operated Powder Inhaler. J Int Med Res 1988;16:201-203 (Pubitemid 18145571)
33. Brindley A, Sumby BS, Smith IS, Prime D, Haywood PA, Grant AC. Design, manufacture and dose consistency of Serevent Diskus inhaler. Pharm Tech Eur 1995;7:14-22.
34. Borgstrom L, Bondesson E, Moren F, Trofast E, Newman SP. Lung deposition of budesonide inhaled via Turbuhaler: a comparison with terbutaline sulphate in normal subjects. Eur Respir J 1994;7:69-73. http://dx.doi.org/10.1183/09031936. 94.07010069 (Pubitemid 24075127)
35. Frijlink HW, De Boer AH. Dry powder inhalers for pulmonary drug delivery. Expert Opin Drug Deliv 2004;1:67-86. http://dx.doi.org/10.1517/17425247.1.1.67 (Pubitemid 40297957)
36. Brown PH, Ning AC, Greening AP, McLean A, Crompton GK. Peak inspiratory flow through Turbuhaler in acute asthma. Eur Respir J 1995;8(11):1940-1941 http://dx.doi.org/10.1183/09031936.95.08111940
37. Meakin BJ, Cainey J, Woodcock PM. Effect of exposure to humidity on terbutaline delivery from Turbuhaler dry powder inhalation devices. (Letter). Eur Respir J 1993;6:760-761 (Pubitemid 23160280)
38. Molimard M, Raherison C, Lignot S, Depont F, Abouelfath A, Moore N. Assessment of handling of inhaler devices in real life: an observational study in 3811 patients in primary care. J Aerosol Med 2003;16:249-254 http://dx.doi.org/10.1089/089426803769017613 (Pubitemid 37169635)
39. Chapman KR, Voshaar TH, Virchow JC. Inhaler choice in primary care. Eur Respir Rev 2005;14:117-122 http://dx.doi.org/10.1183/09059180.05.00009607
40. van der Palen J, Klein JJ, Kerkhoff AH, van Herwaarden CL, Seydel ER. Evaluation of the long-term effectiveness of three instruction modes for inhaling medicines. Patient Educ Couns 1997;32(1 Suppl):S87-95. http://dx.doi.org/10.1016/S0738-3991(97)00100-106 (Pubitemid 28050010)
41. van der Palen J, Klein JJ, van Herwaarden CL, Zielhuis GA, Seydel ER. Multiple inhalers confuse asthma patients. Eur Respir J 1999;14:1034-1037 http://dx.doi.org/10.1183/ 09031936.99.14510349
42. Kesten S, Zive K, Chapman KR. Pharmacist knowledge and ability to use inhaled medication delivery systems. Chest 1993;104:1737-1742 http://dx.doi.org/10.1378/ chest.104.6.1737 (Pubitemid 23360103)
43. Hanania NA, Wittman R, Kesten S, Chapman KR. Medical personnel's knowledge of and ability to use inhaling devices. Metered-dose inhalers, spacing chambers, and breath-actuated dry powder inhalers. Chest 1994;105:111-116 http://dx.doi.org/10.1378/chest.105.1.111 (Pubitemid 24029087)
44. Plaza V, Sanchis J. Medical personnel and patient skill in the use of metered does inhalers: a multicentre study. CESEA Group. Respiration 1998;6:195-198 http://dx.doi.org/10.1159/000029259 (Pubitemid 28302298)
45. Darr MS, Self TH, Ryan MR, Vanderbush RE, Boswell RL. Content and retention evaluation of an audiovisual patient-education program on bronchodilators. Am J Hosp Pharm 1981;38:672-675
46. Kesten S, Elias M, Cartier A, Chapman KR. Patient handling of a multidose dry powder inhalation device for albuterol. Chest 1994;105:1077-1081 http://dx.doi.org/10.1378/chest.105.4.1077 (Pubitemid 24112793)
47. Newman SP, Clarke SW. Inhalation devices and techniques, in: Clark TJH, Godfrey S and Lee TH, 3rd Ed. London: Chapman & Hall Medical 1992, p.469-505
48. Geller DE. Comparing clinical features of the nebulizer, metered-dose inhaler, and dry powder inhaler. Respir Care 2005;50:1313-1321 (Pubitemid 46173315)