Antitumor activity of placenta-derived mesenchymal stem cells producing pigment epithelium-derived factor in a mouse melanoma model

Oncology Letters

Volumn 4, Issue 3, 2012, Pages 413-418

  Chen, Qiaoling ^a   Cheng, Ping ^a   Song, Na ^a   Yin, Tao ^a   He, Hong ^a   Yang, Li ^a   Chen, Xiancheng ^a   Wei, Yuquan ^a  

^a SICHUAN UNIVERSITY   (China)

Author keywords

Anti angiogenesis; Gene therapy; Melanoma; Mesenchymal stem cells; Pigment epithelium derived factor

Indexed keywords

PIGMENT EPITHELIUM DERIVED FACTOR;

ADENOVIRUS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIANGIOGENIC ACTIVITY; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; C57BL 6 MOUSE; CONTROLLED STUDY; DNA MODIFICATION; FEMALE; GENE DELIVERY SYSTEM; GENETIC TRANSDUCTION; HUMAN; HUMAN CELL; MELANOMA B16; MESENCHYMAL STEM CELL; MOUSE; NONHUMAN; PLACENTA; PLACENTA DERIVED MESENCHYMAL STEM CELL; PROTEIN EXPRESSION; STEM CELL GENE THERAPY; TREATMENT OUTCOME; TUMOR VOLUME; VIRUS RECOMBINANT;

EID: 84863863304     PISSN: 17921074     EISSN: 17921082     Source Type: Journal    
DOI: 10.3892/ol.2012.772     Document Type: Article

References (33)

1. Soengas MS and Lowe SW: Apoptosis and melanoma chemoresistance. Oncogene 22: 3138-3151, 2003.
2. Rook G: Tumours and Coley's toxins. Nature 357: 545, 1992.
3. Dass CR, Tran TM and Choong PF: Angiogenesis inhibitors and the need for anti-angiogenic therapeutics. J Dent Res 86: 927-936, 2007.
4. Dawson DW, Volpert OV, Gillis P, et al: Pigment epithelium-derived factor: a potent inhibitor of angiogenesis. Science 285: 245-248, 1999.
5. Elayappan B, Ravinarayannan H, Pasha SP, Lee KJ and Gurunathan S: PEDF inhibits VEGF-and EPO-induced angiogenesis in retinal endothelial cells through interruption of PI3K/Akt phosphorylation. Angiogenesis 12: 313-324, 2009.
6. Doll JA, Stellmach VM, Bouck NP, et al: Pigment epithelium-derived factor regulates the vasculature and mass of the prostate and pancreas. Nat Med 9: 774-780, 2003.
7. Yang LP, Cheng P, Peng XC, et al: Anti-tumor effect of adenovirus-mediated gene transfer of pigment epithelium-derived factor on mouse B16-F10 melanoma. J Exp Clin Cancer Res 28: 75, 2009.
8. Fritz V and Jorgensen C: Mesenchymal stem cells: an emerging tool for cancer targeting and therapy. Curr Stem Cell Res Ther 3: 32-42, 2008.
9. Rao MS and Mattson MP: Stem cells and aging: expanding the possibilities. Mech Ageing Dev 122: 713-734, 2001.
10. Pasquinelli G, Tazzari P, Ricci F, et al: Ultrastructural characteristics of human mesenchymal stromal (stem) cells derived from bone marrow and term placenta. Ultrastruct Pathol 31: 23-31, 2007.
11. Rus Ciuca D, Soritau O, Susman S, Pop VI and Mihu CM: Isolation and characterization of chorionic mesenchyal stem cells from the placenta. Rom J Morphol Embryol 52: 803-808, 2011.
12. In 't Anker PS, Scherjon SA, Kleijburg-van der Keur C, et al: Isolation of mesenchymal stem cells of fet al or maternal origin from human placenta. Stem Cells 22: 1338-1345, 2004.
13. Kadam S, Muthyala S, Nair P and Bhonde R: Human placenta-derived mesenchymal stem cells and islet-like cell clusters generated from these cells as a novel source for stem cell therapy in diabetes. Rev Diabet Stud 7: 168-182, 2010.
14. Mihu CM, Mihu D, Costin N, Rus Ciuca D, Susman S and Ciortea R: Isolation and characterization of stem cells from the placenta and the umbilical cord. Rom J Morphol Embryol 49: 441-446, 2008.
15. Chang CJ, Yen ML, Chen YC, et al: Placenta-derived multipotent cells exhibit immunosuppressive properties that are enhanced in the presence of interferon-gamma. Stem Cells 24: 2466-2477, 2006.
16. Jaffe EA, Nachman RL, Becker CG and Minick CR: Culture of human endothelial cells derived from umbilical veins. Identification by morphologic and immunologic criteria. J Clin Invest 52: 2745-2756, 1973.
17. Liu JY, Wei YQ, Yang L, et al: Immunotherapy of tumors with vaccine based on quail homologous vascular endothelial growth factor receptor-2. Blood 102: 1815-1823, 2003.
18. Cao G, O'Brien CD, Zhou Z, et al: Involvement of human PECAM-1 in angiogenesis and in vitro endothelial cell migration. Am J Physiol Cell Physiol 282: C1181-C1190, 2002.
19. Zhang S, Cao Z, Tian H, et al: SKLB1002, a novel potent inhibitor of VEGF receptor 2 signaling, inhibits angiogenesis and tumor growth in vivo. Clin Cancer Res 17: 4439-4450, 2011.
20. Hu M, Yang JL, Teng H, et al: Anti-angiogenesis therapy based on the bone marrow-derived stromal cells genetically engineered to express sFlt-1 in mouse tumor model. BMC Cancer 8: 306, 2008.
21. Wang L, Schmitz V, Perez-Mediavilla A, Izal I, Prieto J and QianC: Suppression of angiogenesis and tumor growth by adenoviral-mediated gene transfer of pigment epithelium-derived factor. Mol Ther 8: 72-79, 2003.
22. Peng XC, Yang L, Yang LP, et al: Efficient inhibition of murine breast cancer growth and metastasis by gene transferred mouse survivin Thr34-->Ala mutant. J Exp Clin Cancer Res 27: 46, 2008.
23. North S, Moenner M and Bikfalvi A: Recent developments in the regulation of the angiogenic switch by cellular stress factors in tumors. Cancer Lett 218: 1-14, 2005.
24. Emmett MS, Dewing D and Pritchard-Jones RO: Angiogenesis and melanoma-from basic science to clinical trials. Am J Cancer Res 1: 852-868, 2011.
25. Ek ET, Dass CR and Choong PF: Pigment epithelium-derived factor: a multimodal tumor inhibitor. Mol Cancer Ther 5: 1641-1646, 2006.
26. Garcia M, Fernandez-Garcia NI, Rivas V, et al: Inhibition of xenografted human melanoma growth and prevention of metastasis development by dual antiangiogenic/antitumor activities of pigment epithelium-derived factor. Cancer Res 64: 5632-5642, 2004.
27. Abe R, Shimizu T, Yamagishi S, et al: Overexpression of pigment epithelium-derived factor decreases angiogenesis and inhibits the growth of human malignant melanoma cells in vivo. Am J Pathol 164: 1225-1232, 2004.
28. Evangelista M, Soncini M and Parolini O: Placenta-derived stem cells: new hope for cell therapy? Cytotechnology 58: 33-42, 2008.
29. Parolini O, Alviano F, Bagnara GP, et al: Concise review: isolation and characterization of cells from human term placenta: outcome of the first international Workshop on Placenta Derived Stem Cells. Stem Cells 26: 300-311, 2008.
30. Wagner JE, Rosenthal J, Sweetman R, et al: Successful transplantation of HLA-matched and HLA-mismatched umbilical cord blood from unrelated donors: analysis of engraftment and acute graft-versus-host disease. Blood 88: 795-802, 1996.
31. Bailo M, Soncini M, Vertua E, et al: Engraftment potential of human amnion and chorion cells derived from term placenta. Transplantation 78: 1439-1448, 2004.
32. Meng XT, Li C, Dong ZY, et al: Co-transplantation of bFGF-expressing amniotic epithelial cells and neural stem cells promotes functional recovery in spinal cord-injured rats. Cell Biol Int 32: 1546-1558, 2008.
33. Sankar V and Muthusamy R: Role of human amniotic epithelial cell transplantation in spinal cord injury repair research. Neuroscience 118: 11-17, 2003.