Inhibitory effect of ginsenoside Rg1 on extracellular matrix production via extracellular signal-regulated protein kinase/activator protein 1 pathway in nasal polyp-derived fibroblasts

Experimental Biology and Medicine

Volumn 237, Issue 6, 2012, Pages 663-669

  Cho, Jung Sun ^a   Moon, You Mi ^a   Um, Ji Young ^a   Moon, Jun Hyeok ^a   Park, Il Ho ^b   Lee, Heung Man ^a,b,c  

^a Korea University   (South Korea)

^b Korea University College of Medicine   (South Korea)

^c Korea University College of Medicine   (South Korea)

Author keywords

AP 1; Extracellular matrix; Ginsenoside Rg1; MAPK; Myofibroblasts; Nasal polyp; NF B; Smad2 3; TGF 1

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; COLLAGEN TYPE 1; FIBRONECTIN; GINSENOSIDE RG 1; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE 1; RECOMBINANT TRANSFORMING GROWTH FACTOR BETA1; SMAD2 PROTEIN; SMAD3 PROTEIN; STRESS ACTIVATED PROTEIN KINASE; SYNAPTOPHYSIN; TRANSCRIPTION FACTOR AP 1;

ARTICLE; CELL DIFFERENTIATION; CELL ISOLATION; CHRONIC RHINOSINUSITIS; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOTOXICITY; EXTRACELLULAR MATRIX; FIBROBLAST; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOFLUORESCENCE TEST; MYOFIBROBLAST; NOSE POLYP; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

ACTINS; CELL DIFFERENTIATION; CELLS, CULTURED; COLLAGEN TYPE I; EXTRACELLULAR MATRIX; FIBROBLASTS; FIBRONECTINS; GINSENOSIDES; HUMANS; MAP KINASE SIGNALING SYSTEM; NASAL POLYPS; NF-KAPPA B; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTOR AP-1; TRANSFORMING GROWTH FACTOR BETA1;

PANAX GINSENG;

EID: 84863839503     PISSN: 15353702     EISSN: 15353699     Source Type: Journal    
DOI: 10.1258/ebm.2012.011342     Document Type: Article

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