MDCK cell-cultured influenza virus vaccine protects mice from lethal challenge with different influenza viruses

Applied Microbiology and Biotechnology

Volumn 94, Issue 5, 2012, Pages 1173-1179

  Liu, Kun ^a   Yao, Zhidong ^a   Zhang, Liangyan ^a   Li, Junli ^a,b   Xing, Li ^a   Wang, Xiliang ^a  

^a BEIJING INSTITUTE OF MICROBIOLOGY AND EPIDEMIOLOGY   (China)

^b NORTHWEST A F UNIVERSITY   (China)

Author keywords

Influenza virus; MDCK bioreactor; Vaccine

Indexed keywords

CELL CONCENTRATIONS; CELL-BASED; CULTURE SYSTEMS; GENERAL POPULATION; HEALTH CONCERNS; INFLUENZA VACCINES; INFLUENZA VIRUS; MADIN-DARBY CANINE KIDNEY CELLS; MANUFACTURE SYSTEM; MANUFACTURING METHODS; MOUSE MODELS; PANDEMIC INFLUENZA; T-CELL RESPONSE;

BIOCONVERSION; BIOREACTORS; CELL CULTURE; CELLS; MAMMALS; VACCINES;

VIRUSES;

INFLUENZA VACCINE;

ANTIBODY; BIOREACTOR; CONCENTRATION (COMPOSITION); CYTOLOGY; DISEASE RESISTANCE; EPIDEMIC; INFLUENZA; MANUFACTURING; NEUTRALIZATION; PRODUCTION SYSTEM; RODENT; VACCINATION; VACCINE;

ANIMAL CELL; ANTIGENICITY; ARTICLE; BIOREACTOR; CELL CULTURE; CELL STRAIN; DOG; IMMUNOGENICITY; INFLUENZA VIRUS; KIDNEY CELL; MICROCARRIER CULTURE; NONHUMAN; PANDEMIC INFLUENZA; T LYMPHOCYTE; VIRUS NEUTRALIZATION; VIRUS STRAIN; VIRUS TITRATION;

ANIMALS; ANTIBODIES, NEUTRALIZING; ANTIBODIES, VIRAL; BIOREACTORS; BIOTECHNOLOGY; CELL CULTURE TECHNIQUES; CELL LINE; CROSS PROTECTION; DISEASE MODELS, ANIMAL; DOGS; INFLUENZA VACCINES; MICE; ORTHOMYXOVIRIDAE; ORTHOMYXOVIRIDAE INFECTIONS; SURVIVAL ANALYSIS; T-LYMPHOCYTES; TECHNOLOGY, PHARMACEUTICAL; VIRAL LOAD;

MUS; ORTHOMYXOVIRIDAE;

EID: 84863829858     PISSN: 01757598     EISSN: 14320614     Source Type: Journal    
DOI: 10.1007/s00253-011-3860-8     Document Type: Article

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