The effect of a whole-system approach in an antimicrobial stewardship programme at the Singapore General Hospital

European Journal of Clinical Microbiology and Infectious Diseases

Volumn 31, Issue 6, 2012, Pages 947-955

  Teo, J ^a   Kwa, A L H ^a   Loh, J ^a   Chlebicki, M P ^a   Lee, W ^a  

^a SINGAPORE GENERAL HOSPITAL   (Singapore)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIINFECTIVE AGENT; CEFEPIME; CILASTATIN PLUS IMIPENEM; CIPROFLOXACIN; ERTAPENEM; MEROPENEM; PIPERACILLIN PLUS TAZOBACTAM;

COST CONTROL; DRUG SURVEILLANCE PROGRAM; DRUG USE; GENERAL HOSPITAL; INAPPROPRIATE PRESCRIBING; MEDICAL DECISION MAKING; ORGANIZATIONAL DOWNSIZING; ORGANIZATIONAL EFFICIENCY; OUTCOME ASSESSMENT; PATIENT ASSESSMENT; PATIENT SAFETY; PHYSICIAN ATTITUDE; PRACTICE GUIDELINE; PRESCRIPTION; PRIORITY JOURNAL; PROCESS OPTIMIZATION; PROFESSIONAL COMPETENCE; PROFESSIONAL KNOWLEDGE; PROGRAM DEVELOPMENT; REVIEW; SINGAPORE; TOTAL QUALITY MANAGEMENT; ARTICLE; BACTERIAL INFECTION; DRUG THERAPY; DRUG UTILIZATION; HEALTH SERVICES RESEARCH; HUMAN; POLICY; STANDARD; STATISTICS;

ANTI-BACTERIAL AGENTS; BACTERIAL INFECTIONS; DRUG THERAPY; DRUG UTILIZATION; HEALTH SERVICES RESEARCH; HOSPITALS, GENERAL; HUMANS; ORGANIZATIONAL POLICY; PRESCRIPTIONS; SINGAPORE;

EID: 84863829693     PISSN: 09349723     EISSN: 14354373     Source Type: Journal    
DOI: 10.1007/s10096-011-1391-y     Document Type: Review

References (23)

1. National Nosocomial Infections Surveillance System (2004) National Nosocomial Infections Surveillance (NNIS) System Report, data summary from January 1992 through June 2004, issued October 2004. Am J Infect Control 32:470-485
2. Hsu LY, Tan TY, Jureen R, Koh TH, Krishnan P, Tzer-Pin Lin R, Wen-Sin Tee N, Tambyah PA (2007) Antimicrobial drug resistance in Singapore hospitals. Emerg Infect Dis 13 (12):1944-1947 (Pubitemid 350252975)
3. Kwa AL, Low JG, Lee E, Kurup A, Chee HL, Tam VH (2007) The impact of multidrug resistance on the outcomes of critically ill patients with Gram-negative bacterial pneumonia. Diagn Microbiol Infect Dis 58(1):99-104 (Pubitemid 46694269)
4. Hsu LY, Tan TY, Tam VH, Kwa A, Fisher DA, Koh TH, Network for Antimicrobial Resistance Surveillance (Singapore) (2010) Surveillance and correlation of antibiotic prescription and resistance of Gram-negative bacteria in Singaporean hospitals. Antimicrob Agents Chemother 54(3):1173-1178
5. Quek CL (2007) A retrospective study evaluating the use of imipenem and meropenem in a tertiary referral hospital in Singapore. Abstracts of Singapore General Hospital (SGH) 16th Annual Scientific Meeting, Singapore, 27-28 April 2007
6. Shlaes DM, Gerding DN, John JF Jr, Craig WA, Bornstein DL, Duncan RA, Eckman MR, Farrer WE, Greene WH, Lorian V, Levy S, McGowan JE Jr, Paul SM, Ruskin J, Tenover FC, Watanakunakorn C (1997) Society for Healthcare Epidemiology of America and Infectious Diseases Society of America Joint Committee on the Prevention of Antimicrobial Resistance: guidelines for the prevention of antimicrobial resistance in hospitals. Clin Infect Dis 25:584-599 (Pubitemid 127774277)
7. Dellit TH, Owens RC, McGowan JE Jr, Gerding DN, Weinstein RA, Burke JP, Huskins WC, Paterson DL, Fishman NO, Carpenter CF, Brennan PJ, Billeter M, Hooton TM, Infectious Diseases Society of America, Society for Healthcare Epidemiology of America (2007) Infectious Diseases Society of America and the Society for Healthcare Epidemiology of America guidelines for developing an institutional program to enhance antimicrobial stewardship. Clin Infect Dis 44:159-177 (Pubitemid 46084814)
8. Lawton RM, Fridkin SK, Gaynes RP, McGowan JE Jr (2000) Practices to improve antimicrobial use at 47 US hospitals: the status of the 1997 SHEA/IDSA position paper recommendations. Society for Healthcare Epidemiology of America/Infectious Diseases Society of America. Infect Control Hosp Epidemiol 21 (4):256-259
9. Lomas J, Anderson GM, Domnick-Pierre K, Vayda E, Enkin MW, Hannah WJ (1989) Do practice guidelines guide practice? The effect of a consensus statement on the practice of physicians. N Engl J Med 321(19):1306-1311 (Pubitemid 19267218)
10. Grol R (2001) Successes and failures in the implementation of evidence-based guidelines for clinical practice. Med Care 39 (Suppl 2):II46-II54 (Pubitemid 33752650)
11. Hulscher ME, Grol RP, van der Meer JW (2010) Antibiotic prescribing in hospitals: a social and behavioural scientific approach. Lancet Infect Dis 10:167-175
12. Charani E, Cooke J, Holmes A (2010) Antibiotic stewardship programmes-what's missing? J Antimicrob Chemother 65:2275- 2277
13. Ansari F, Gray K, Nathwani D, Phillips G, Ogston S, Ramsay C, Davey P (2003) Outcomes of an intervention to improve hospital antibiotic prescribing: interrupted time series with segmented regression analysis. J Antimicrob Chemother 52:842-848 (Pubitemid 37407814)
14. Ng CK, Wu TC, Chan WM, Leung YS, Li CK, Tsang DN, Leung GM (2008) Clinical and economic impact of an antibiotics stewardship programme in a regional hospital in Hong Kong. Qual Saf Health Care 17(5):387-392
15. Raineri E, Pan A, Mondello P, Acquarolo A, Candiani A, Crema L (2008) Role of the infectious diseases specialist consultant on the appropriateness of antimicrobial therapy prescription in an intensive care unit. Am J Infect Control 36 (4):283-290 (Pubitemid 351622018)
16. Halm EA, Horowitz C, Silver A, Fein A, Dlugacz YD, Hirsch B, Chassin MR (2004) Limited impact of a multicenter intervention to improve the quality and efficiency of pneumonia care. Chest 126(1):100-107 (Pubitemid 38943124)
17. Cosgrove SE, Patel A, Song XY, Miller RE, Speck K, Banowetz A, Hadler R, Sinkowitz-Cochran RL, Cardo DM, Srinivasan A (2007) Impact of different methods of feedback to clinicians after postprescription antimicrobial review based on the Centers for Disease Control and Prevention's 12 Steps to Prevent Antimicrobial Resistance Among Hospitalized Adults. Infect Control Hosp Epidemiol 28(6):641-646 (Pubitemid 46954747)
18. LaRocco A Jr (2003) Concurrent antibiotic review programs-a role for infectious diseases specialists at small community hospitals. Clin Infect Dis 37(5):742-743 (Pubitemid 37100825)
19. Chia J (2011) The rise of the superbug. Singapore Health Services HealthXchange. Available online at: http://www.healthxchange.com.sg/ healthyliving/SpecialFocus/Pages/The-rise-of-the-superbug.aspx. Last accessed 11th June 2011
20. Schentag JJ (1998) Antibiotic dosing-does one size fit all? JAMA 279:159-160 (Pubitemid 28068309)
21. Tonna AP, Stewart D, West B, Gould I, McCaig D (2008) Antimicrobial optimisation in secondary care: the pharmacist as part of a multidisciplinary antimicrobial programme-a literature review. Int J Antimicrob Agents 31(6):511-517
22. American Society of Health System Pharmacists (ASHP) (2010) ASHP statement on the pharmacist's role in antimicrobial stewardship and infection prevention and control. Am J Health Syst Pharm 67(7):575-577
23. Thaler R, Sunstein C (2008) Nudge: improving decisions about health, wealth and happiness. Yale University Press, New Haven, CT