Highly enantioselective organocatalytic trifluoromethyl carbinol synthesis-a caveat on reaction times and product isolation

Journal of the American Chemical Society

Volumn 134, Issue 27, 2012, Pages 11196-11205

  Duangdee, Nongnaphat ^a   Harnying, Wacharee ^a   Rulli, Giuseppe ^b   Neudörfl, Jörg M ^a   Gröger, Harald ^b,c   Berkessel, Albrecht ^a  

^a UNIVERSITY OF COLOGNE   (Germany)

^b UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

^c BIELEFELD UNIVERSITY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ABSOLUTE CONFIGURATION; ACID-FREE; ALDOL REACTIONS; AMMONIUM CHLORIDE; CATALYST EFFECTS; CATALYTIC TRANSFORMATION; ENANTIOMERIC PURITY; ENANTIOSELECTIVE; INTRAMOLECULAR VARIANTS; KINETIC CONTROL; ORGANIC SYNTHESIS; ORGANOCATALYSTS; ORGANOCATALYTIC; ORGANOCATALYTIC TRANSFORMATION; PRODUCT ISOLATION; PROTIC SOLVENTS; REACTION MONITORING; TERTIARY ALCOHOLS; TRIFLUOROMETHYL; WEAK ACIDS; X RAY STRUCTURAL ANALYSIS;

AMMONIUM COMPOUNDS; CATALYSTS; CHLORINE COMPOUNDS; ENANTIOSELECTIVITY; IONIC LIQUIDS; METHANOL; X RAY CRYSTALLOGRAPHY;

FACE RECOGNITION;

ACETONE; AMIDE; AMMONIUM CHLORIDE; ELECTROPHILE; KETONE DERIVATIVE; METHANOL DERIVATIVE; PYRROLIDINE DERIVATIVE; SOLVENT; TRIFLUOROMETHYL CARBINOL; UNCLASSIFIED DRUG;

ALDOL REACTION; ARTICLE; CATALYST; CHEMICAL ANALYSIS; CHEMICAL REACTION KINETICS; CRYSTAL STRUCTURE; ENANTIOMER; ENANTIOSELECTIVITY; FLUORINE NUCLEAR MAGNETIC RESONANCE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; ISOLATION PROCEDURE; RACEMIZATION; REACTION TIME; STRUCTURE ANALYSIS; SYNTHESIS; X RAY CRYSTALLOGRAPHY;

ACETONE; ACETOPHENONES; ALDEHYDES; CATALYSIS; CRYSTALLOGRAPHY, X-RAY; HYDROCARBONS, FLUORINATED; MAGNETIC RESONANCE SPECTROSCOPY; METHANOL; MODELS, MOLECULAR; STEREOISOMERISM;

EID: 84863822627     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/ja302511t     Document Type: Article

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