Identification and in-vitro ADME assessment of a series of novel anti-malarial agents suitable for hit-to-lead chemistry

ACS Medicinal Chemistry Letters

Volumn 3, Issue 7, 2012, Pages 570-573

  Edlin, Chris D ^a   Morgans, Garreth ^a   Winks, Susan ^a   Duffy, Sandra ^d   Avery, Vicky M ^d   Wittlin, Sergio ^b   Waterson, David ^c   Burrows, Jeremy ^c   Bryans, Justin ^e  

^a iThemba Pharmaceuticals   (South Africa)

^b SWISS TROPICAL AND PUBLIC HEALTH INSTITUTE   (Switzerland)

^c ICC   (Switzerland)

^d GRIFFITH UNIVERSITY   (Australia)

^e MEDICAL RESEARCH COUNCIL   (United Kingdom)

Author keywords

hit to lead chemistry; phenotypic screening; Plasmodium falciparum; Screening

Indexed keywords

ANTIMALARIAL AGENT; BENZIMIDAZOLE; CHLOROQUINE; QUINAZOLINE DERIVATIVE; SULFANILAMIDE; SULFONAMIDE;

ARTICLE; DRUG IDENTIFICATION; HIGH THROUGHPUT SCREENING; IN VITRO STUDY; IN VIVO STUDY; MALARIA; NONHUMAN; PLASMODIUM BERGHEI; PLASMODIUM FALCIPARUM; PRIORITY JOURNAL;

MURINAE; PLASMODIUM BERGHEI; PLASMODIUM FALCIPARUM;

EID: 84863821880     PISSN: None     EISSN: 19485875     Source Type: Journal    
DOI: 10.1021/ml300091c     Document Type: Article

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