-
3
-
-
0030897007
-
Mantle cell lymphoma: a clinicopathologic study of 80 cases
-
Argatoff LH, Connors JM, Klasa RJ, Horsman DE, Gascoyne RD: Mantle cell lymphoma: a clinicopathologic study of 80 cases. Blood. 1997; 89(6):2067-2078.
-
(1997)
Blood
, vol.89
, Issue.6
, pp. 2067-2078
-
-
Argatoff, L.H.1
Connors, J.M.2
Klasa, R.J.3
Horsman, D.E.4
Gascoyne, R.D.5
-
5
-
-
2642618607
-
Mantle cell lymphoma: presenting features, response to therapy, and prognostic factors
-
Bosch F, Lopez-Guillermo A, Campo E, Ribera JM, Conde E, Piris MA, Vallespi T, Woessner S, Montserrat E: Mantle cell lymphoma: presenting features, response to therapy, and prognostic factors. Cancer. 1998; 82(3):567-575.
-
(1998)
Cancer
, vol.82
, Issue.3
, pp. 567-575
-
-
Bosch, F.1
Lopez-Guillermo, A.2
Campo, E.3
Ribera, J.M.4
Conde, E.5
Piris, M.A.6
Vallespi, T.7
Woessner, S.8
Montserrat, E.9
-
6
-
-
24144472585
-
Biology and therapy of mantle cell lymphoma
-
Williams ME, Densmore JJ: Biology and therapy of mantle cell lymphoma. Curr Opin Oncol. 2005; 17(5):425-431.
-
(2005)
Curr Opin Oncol
, vol.17
, Issue.5
, pp. 425-431
-
-
Williams, M.E.1
Densmore, J.J.2
-
7
-
-
33646894078
-
Mantle cell lymphoma: an update on management
-
Zelenetz AD: Mantle cell lymphoma: an update on management. Ann Oncol. 2006; 17 Suppl 4:iv12-14.
-
(2006)
Ann Oncol
, Issue.17 SUPPL.
-
-
Zelenetz, A.D.1
-
8
-
-
34249704600
-
Immunochemotherapy with rituximab and overall survival in patients with indolent or mantle cell lymphoma: a systematic review and meta-analysis
-
Schulz H, Bohlius JF, Trelle S, Skoetz N, Reiser M, Kober T, Schwarzer G, Herold M, Dreyling M, Hallek M, Engert A: Immunochemotherapy with rituximab and overall survival in patients with indolent or mantle cell lymphoma: a systematic review and meta-analysis. J Natl Cancer Inst. 2007; 99(9):706-714.
-
(2007)
J Natl Cancer Inst
, vol.99
, Issue.9
, pp. 706-714
-
-
Schulz, H.1
Bohlius, J.F.2
Trelle, S.3
Skoetz, N.4
Reiser, M.5
Kober, T.6
Schwarzer, G.7
Herold, M.8
Dreyling, M.9
Hallek, M.10
Engert, A.11
-
9
-
-
34250199957
-
New directions in the treatment of mantle cell lymphoma: an overview
-
Goy A: New directions in the treatment of mantle cell lymphoma: an overview. Clin Lymphoma Myeloma. 2006; 7 Suppl 1:S24-32.
-
(2006)
Clin Lymphoma Myeloma
, Issue.7 SUPPL.
-
-
Goy, A.1
-
10
-
-
35748958102
-
Expanding therapeutic options in mantle cell lymphoma
-
Goy A, Feldman T: Expanding therapeutic options in mantle cell lymphoma. Clin Lymphoma Myeloma. 2007; 7 Suppl 5:S184-191.
-
(2007)
Clin Lymphoma Myeloma
, Issue.7 SUPPL. 5
-
-
Goy, A.1
Feldman, T.2
-
11
-
-
77449116884
-
Mantle cell lymphoma: biological insights and treatment advances
-
Leonard JP, Williams ME, Goy A, Grant S, Pfreundschuh M, Rosen ST, Sweetenham JW: Mantle cell lymphoma: biological insights and treatment advances. Clin Lymphoma Myeloma. 2009; 9(4):267-277.
-
(2009)
Clin Lymphoma Myeloma
, vol.9
, Issue.4
, pp. 267-277
-
-
Leonard, J.P.1
Williams, M.E.2
Goy, A.3
Grant, S.4
Pfreundschuh, M.5
Rosen, S.T.6
Sweetenham, J.W.7
-
12
-
-
84862194194
-
Outcome of deferred initial therapy in mantle-cell lymphoma
-
Martin P, Chadburn A, Christos P, Weil K, Furman RR, Ruan J, Elstrom R, Niesvizky R, Ely S, Diliberto M, Melnick A, Knowles DM, Chen-Kiang S, Coleman M, Leonard JP: Outcome of deferred initial therapy in mantle-cell lymphoma. J Clin Oncol. 2009; 27(8):1209-1213.
-
(2009)
J Clin Oncol
, vol.27
, Issue.8
, pp. 1209-1213
-
-
Martin, P.1
Chadburn, A.2
Christos, P.3
Weil, K.4
Furman, R.R.5
Ruan, J.6
Elstrom, R.7
Niesvizky, R.8
Ely, S.9
Diliberto, M.10
Melnick, A.11
Knowles, D.M.12
Chen-Kiang, S.13
Coleman, M.14
Leonard, J.P.15
-
13
-
-
46249131868
-
Intensive treatment strategies may not provide superior outcomes in mantle cell lymphoma: overall survival exceeding 7 years with standard therapies
-
Martin P, Chadburn A, Christos P, Furman R, Ruan J, Joyce MA, Fusco E, Glynn P, Elstrom R, Niesvizky R, Feldman EJ, Shore TB, Schuster MW, Ely S, Knowles DM, Chen-Kiang S et al: Intensive treatment strategies may not provide superior outcomes in mantle cell lymphoma: overall survival exceeding 7 years with standard therapies. Ann Oncol. 2008; 19(7):1327-1330.
-
(2008)
Ann Oncol
, vol.19
, Issue.7
, pp. 1327-1330
-
-
Martin, P.1
Chadburn, A.2
Christos, P.3
Furman, R.4
Ruan, J.5
Joyce, M.A.6
Fusco, E.7
Glynn, P.8
Elstrom, R.9
Niesvizky, R.10
Feldman, E.J.11
Shore, T.B.12
Schuster, M.W.13
Ely, S.14
Knowles, D.M.15
Chen-Kiang, S.16
-
14
-
-
59149105528
-
Improvement of overall survival in advanced stage mantle cell lymphoma
-
Herrmann A, Hoster E, Zwingers T, Brittinger G, Engelhard M, Meusers P, Reiser M, Forstpointner R, Metzner B, Peter N, Wormann B, Trumper L, Pfreundschuh M, Einsele H, Hiddemann W, Unterhalt M et al: Improvement of overall survival in advanced stage mantle cell lymphoma. J Clin Oncol. 2009; 27(4):511-518.
-
(2009)
J Clin Oncol
, vol.27
, Issue.4
, pp. 511-518
-
-
Herrmann, A.1
Hoster, E.2
Zwingers, T.3
Brittinger, G.4
Engelhard, M.5
Meusers, P.6
Reiser, M.7
Forstpointner, R.8
Metzner, B.9
Peter, N.10
Wormann, B.11
Trumper, L.12
Pfreundschuh, M.13
Einsele, H.14
Hiddemann, W.15
Unterhalt, M.16
-
15
-
-
27244452464
-
High rate of durable remissions after treatment of newly diagnosed aggressive mantle-cell lymphoma with rituximab plus hyper-CVAD alternating with rituximab plus high-dose methotrexate and cytarabine
-
Romaguera JE, Fayad L, Rodriguez MA, Broglio KR, Hagemeister FB, Pro B, McLaughlin P, Younes A, Samaniego F, Goy A, Sarris AH, Dang NH, Wang M, Beasley V, Medeiros LJ, Katz RL et al: High rate of durable remissions after treatment of newly diagnosed aggressive mantle-cell lymphoma with rituximab plus hyper-CVAD alternating with rituximab plus high-dose methotrexate and cytarabine. J Clin Oncol. 2005; 23(28):7013-7023.
-
(2005)
J Clin Oncol
, vol.23
, Issue.28
, pp. 7013-7023
-
-
Romaguera, J.E.1
Fayad, L.2
Rodriguez, M.A.3
Broglio, K.R.4
Hagemeister, F.B.5
Pro, B.6
McLaughlin, P.7
Younes, A.8
Samaniego, F.9
Goy, A.10
Sarris, A.H.11
Dang, N.H.12
Wang, M.13
Beasley, V.14
Medeiros, L.J.15
Katz, R.L.16
-
16
-
-
20144388941
-
Early consolidation by myeloablative radiochemotherapy followed by autologous stem cell transplantation in first remission significantly prolongs progression-free survival in mantle-cell lymphoma: results of a prospective randomized trial of the European MCL Network
-
Dreyling M, Lenz G, Hoster E, Van Hoof A, Gisselbrecht C, Schmits R, Metzner B, Truemper L, Reiser M, Steinhauer H, Boiron JM, Boogaerts MA, Aldaoud A, Silingardi V, Kluin-Nelemans HC, Hasford J et al: Early consolidation by myeloablative radiochemotherapy followed by autologous stem cell transplantation in first remission significantly prolongs progression-free survival in mantle-cell lymphoma: results of a prospective randomized trial of the European MCL Network. Blood. 2005; 105(7):2677-2684.
-
(2005)
Blood
, vol.105
, Issue.7
, pp. 2677-2684
-
-
Dreyling, M.1
Lenz, G.2
Hoster, E.3
Van Hoof, A.4
Gisselbrecht, C.5
Schmits, R.6
Metzner, B.7
Truemper, L.8
Reiser, M.9
Steinhauer, H.10
Boiron, J.M.11
Boogaerts, M.A.12
Aldaoud, A.13
Silingardi, V.14
Kluin-Nelemans, H.C.15
Hasford, J.16
-
17
-
-
53449089095
-
Long-term progression-free survival of mantle cell lymphoma after intensive front-line immunochemotherapy with in vivo-purged stem cell rescue: a nonrandomized phase 2 multicenter study by the Nordic Lymphoma Group
-
Geisler CH, Kolstad A, Laurell A, Andersen NS, Pedersen LB, Jerkeman M, Eriksson M, Nordstrom M, Kimby E, Boesen AM, Kuittinen O, Lauritzsen GF, Nilsson-Ehle H, Ralfkiaer E, Akerman M, Ehinger M et al: Long-term progression-free survival of mantle cell lymphoma after intensive front-line immunochemotherapy with in vivo-purged stem cell rescue: a nonrandomized phase 2 multicenter study by the Nordic Lymphoma Group. Blood. 2008; 112(7):2687-2693.
-
(2008)
Blood
, vol.112
, Issue.7
, pp. 2687-2693
-
-
Geisler, C.H.1
Kolstad, A.2
Laurell, A.3
Andersen, N.S.4
Pedersen, L.B.5
Jerkeman, M.6
Eriksson, M.7
Nordstrom, M.8
Kimby, E.9
Boesen, A.M.10
Kuittinen, O.11
Lauritzsen, G.F.12
Nilsson-Ehle, H.13
Ralfkiaer, E.14
Akerman, M.15
Ehinger, M.16
-
18
-
-
70349560308
-
How I treat mantle cell lymphoma
-
Ghielmini M, Zucca E: How I treat mantle cell lymphoma. Blood. 2009; 114(8):1469-1476.
-
(2009)
Blood
, vol.114
, Issue.8
, pp. 1469-1476
-
-
Ghielmini, M.1
Zucca, E.2
-
19
-
-
0013224058
-
The proliferation gene expression signature is a quantitative integrator of oncogenic events that predicts survival in mantle cell lymphoma
-
Rosenwald A, Wright G, Wiestner A, Chan WC, Connors JM, Campo E, Gascoyne RD, Grogan TM, Muller- Hermelink HK, Smeland EB, Chiorazzi M, Giltnane JM, Hurt EM, Zhao H, Averett L, Henrickson S et al: The proliferation gene expression signature is a quantitative integrator of oncogenic events that predicts survival in mantle cell lymphoma. Cancer Cell. 2003; 3(2):185-197.
-
(2003)
Cancer Cell
, vol.3
, Issue.2
, pp. 185-197
-
-
Rosenwald, A.1
Wright, G.2
Wiestner, A.3
Chan, W.C.4
Connors, J.M.5
Campo, E.6
Gascoyne, R.D.7
Grogan, T.M.8
Muller-Hermelink, H.K.9
Smeland, E.B.10
Chiorazzi, M.11
Giltnane, J.M.12
Hurt, E.M.13
Zhao, H.14
Averett, L.15
Henrickson, S.16
-
20
-
-
10744226486
-
The molecular signature of mantle cell lymphoma reveals multiple signals favoring cell survival
-
Martinez N, Camacho FI, Algara P, Rodriguez A, Dopazo A, Ruiz-Ballesteros E, Martin P, Martinez-Climent JA, Garcia-Conde J, Menarguez J, Solano F, Mollejo M, Piris MA: The molecular signature of mantle cell lymphoma reveals multiple signals favoring cell survival. Cancer Res. 2003; 63(23):8226-8232.
-
(2003)
Cancer Res
, vol.63
, Issue.23
, pp. 8226-8232
-
-
Martinez, N.1
Camacho, F.I.2
Algara, P.3
Rodriguez, A.4
Dopazo, A.5
Ruiz-Ballesteros, E.6
Martin, P.7
Martinez-Climent, J.A.8
Garcia-Conde, J.9
Menarguez, J.10
Solano, F.11
Mollejo, M.12
Piris, M.A.13
-
21
-
-
33747846726
-
Constitutive activation of Akt contributes to the pathogenesis and survival of mantle cell lymphoma
-
Rudelius M, Pittaluga S, Nishizuka S, Pham TH, Fend F, Jaffe ES, Quintanilla-Martinez L, Raffeld M: Constitutive activation of Akt contributes to the pathogenesis and survival of mantle cell lymphoma. Blood. 2006; 108(5):1668-1676.
-
(2006)
Blood
, vol.108
, Issue.5
, pp. 1668-1676
-
-
Rudelius, M.1
Pittaluga, S.2
Nishizuka, S.3
Pham, T.H.4
Fend, F.5
Jaffe, E.S.6
Quintanilla-Martinez, L.7
Raffeld, M.8
-
22
-
-
0038206722
-
Inhibition of constitutive NF-kappa B activation in mantle cell lymphoma B cells leads to induction of cell cycle arrest and apoptosis
-
Pham LV, Tamayo AT, Yoshimura LC, Lo P, Ford RJ: Inhibition of constitutive NF-kappa B activation in mantle cell lymphoma B cells leads to induction of cell cycle arrest and apoptosis. J Immunol. 2003; 171(1):88-95.
-
(2003)
J Immunol
, vol.171
, Issue.1
, pp. 88-95
-
-
Pham, L.V.1
Tamayo, A.T.2
Yoshimura, L.C.3
Lo, P.4
Ford, R.J.5
-
23
-
-
78650985963
-
Mantle cell lymphoma: biology, pathogenesis, and the molecular basis of treatment in the genomic era
-
Perez-Galan P, Dreyling M, Wiestner A: Mantle cell lymphoma: biology, pathogenesis, and the molecular basis of treatment in the genomic era. Blood, 2011; 117(1):26-38.
-
(2011)
Blood
, vol.117
, Issue.1
, pp. 26-38
-
-
Perez-Galan, P.1
Dreyling, M.2
Wiestner, A.3
-
24
-
-
49349095724
-
Monoclonal antibody therapy for B-cell non-Hodgkin's lymphoma
-
Cheson BD, Leonard JP: Monoclonal antibody therapy for B-cell non-Hodgkin's lymphoma. N Engl J Med. 2008; 359(6):613-626.
-
(2008)
N Engl J Med
, vol.359
, Issue.6
, pp. 613-626
-
-
Cheson, B.D.1
Leonard, J.P.2
-
25
-
-
0006818262
-
Treatment of mantle-cell lymphoma with Rituximab (chimeric monoclonal anti-CD20 antibody): analysis of factors associated with response
-
Foran JM, Cunningham D, Coiffier B, Solal-Celigny P, Reyes F, Ghielmini M, Johnson PW, Gisselbrecht C, Bradburn M, Matthews J, Lister TA: Treatment of mantle-cell lymphoma with Rituximab (chimeric monoclonal anti-CD20 antibody): analysis of factors associated with response. Ann Oncol. 2000; 11 Suppl 1:117-121.
-
(2000)
Ann Oncol
, Issue.11 SUPPL.
, pp. 117-121
-
-
Foran, J.M.1
Cunningham, D.2
Coiffier, B.3
Solal-Celigny, P.4
Reyes, F.5
Ghielmini, M.6
Johnson, P.W.7
Gisselbrecht, C.8
Bradburn, M.9
Matthews, J.10
Lister, T.A.11
-
26
-
-
38549174095
-
Immunotherapy in mantle cell lymphoma: anti-CD20-based therapy and beyond
-
Zhou Y, Zhang L, Romaguera J, Delasalle K, Han X, Du X, Kwak L, Yi Q, Wang M: Immunotherapy in mantle cell lymphoma: anti-CD20-based therapy and beyond. Am J Hematol. 2008; 83(2):144-149.
-
(2008)
Am J Hematol
, vol.83
, Issue.2
, pp. 144-149
-
-
Zhou, Y.1
Zhang, L.2
Romaguera, J.3
Delasalle, K.4
Han, X.5
Du, X.6
Kwak, L.7
Yi, Q.8
Wang, M.9
-
27
-
-
20044381673
-
Effect of single-agent rituximab given at the standard schedule or as prolonged treatment in patients with mantle cell lymphoma: a study of the Swiss Group for Clinical Cancer Research (SAKK)
-
Ghielmini M, Schmitz SF, Cogliatti S, Bertoni F, Waltzer U, Fey MF, Betticher DC, Schefer H, Pichert G, Stahel R, Ketterer N, Bargetzi M, Cerny T: Effect of single-agent rituximab given at the standard schedule or as prolonged treatment in patients with mantle cell lymphoma: a study of the Swiss Group for Clinical Cancer Research (SAKK). J Clin Oncol. 2005; 23(4):705-711.
-
(2005)
J Clin Oncol
, vol.23
, Issue.4
, pp. 705-711
-
-
Ghielmini, M.1
Schmitz, S.F.2
Cogliatti, S.3
Bertoni, F.4
Waltzer, U.5
Fey, M.F.6
Betticher, D.C.7
Schefer, H.8
Pichert, G.9
Stahel, R.10
Ketterer, N.11
Bargetzi, M.12
Cerny, T.13
-
28
-
-
20144376591
-
Immunochemotherapy with rituximab and cyclophosphamide, doxorubicin, vincristine, and prednisone significantly improves response and time to treatment failure, but not long-term outcome in patients with previously untreated mantle cell lymphoma: results of a prospective randomized trial of the German Low Grade Lymphoma Study Group (GLSG)
-
Lenz G, Dreyling M, Hoster E, Wormann B, Duhrsen U, Metzner B, Eimermacher H, Neubauer A, Wandt H, Steinhauer H, Martin S, Heidemann E, Aldaoud A, Parwaresch R, Hasford J, Unterhalt M et al: Immunochemotherapy with rituximab and cyclophosphamide, doxorubicin, vincristine, and prednisone significantly improves response and time to treatment failure, but not long-term outcome in patients with previously untreated mantle cell lymphoma: results of a prospective randomized trial of the German Low Grade Lymphoma Study Group (GLSG). J Clin Oncol. 2005; 23(9):1984-1992.
-
(2005)
J Clin Oncol
, vol.23
, Issue.9
, pp. 1984-1992
-
-
Lenz, G.1
Dreyling, M.2
Hoster, E.3
Wormann, B.4
Duhrsen, U.5
Metzner, B.6
Eimermacher, H.7
Neubauer, A.8
Wandt, H.9
Steinhauer, H.10
Martin, S.11
Heidemann, E.12
Aldaoud, A.13
Parwaresch, R.14
Hasford, J.15
Unterhalt, M.16
-
29
-
-
24644476583
-
Combination antibody therapy with epratuzumab and rituximab in relapsed or refractory non-Hodgkin's lymphoma
-
Leonard JP, Coleman M, Ketas J, Ashe M, Fiore JM, Furman RR, Niesvizky R, Shore T, Chadburn A, Horne H, Kovacs J, Ding CL, Wegener WA, Horak ID, Goldenberg DM: Combination antibody therapy with epratuzumab and rituximab in relapsed or refractory non-Hodgkin's lymphoma. J Clin Oncol. 2005; 23(22):5044-5051.
-
(2005)
J Clin Oncol
, vol.23
, Issue.22
, pp. 5044-5051
-
-
Leonard, J.P.1
Coleman, M.2
Ketas, J.3
Ashe, M.4
Fiore, J.M.5
Furman, R.R.6
Niesvizky, R.7
Shore, T.8
Chadburn, A.9
Horne, H.10
Kovacs, J.11
Ding, C.L.12
Wegener, W.A.13
Horak, I.D.14
Goldenberg, D.M.15
-
30
-
-
33748471355
-
Multicenter phase II trial of immunotherapy with the humanized anti-CD22 antibody, epratuzumab, in combination with rituximab, in refractory or recurrent non-Hodgkin's lymphoma
-
Strauss SJ, Morschhauser F, Rech J, Repp R, Solal-Celigny P, Zinzani PL, Engert A, Coiffier B, Hoelzer DF, Wegener WA, Teoh NK, Goldenberg DM, Lister TA: Multicenter phase II trial of immunotherapy with the humanized anti-CD22 antibody, epratuzumab, in combination with rituximab, in refractory or recurrent non-Hodgkin's lymphoma. J Clin Oncol. 2006; 24(24):3880-3886.
-
(2006)
J Clin Oncol
, vol.24
, Issue.24
, pp. 3880-3886
-
-
Strauss, S.J.1
Morschhauser, F.2
Rech, J.3
Repp, R.4
Solal-Celigny, P.5
Zinzani, P.L.6
Engert, A.7
Coiffier, B.8
Hoelzer, D.F.9
Wegener, W.A.10
Teoh, N.K.11
Goldenberg, D.M.12
Lister, T.A.13
-
32
-
-
0035920144
-
Invariant chain induces B cell maturation by activating a TAF(II)105-NF-kappaB-dependent transcription program
-
Matza D, Wolstein O, Dikstein R, Shachar I: Invariant chain induces B cell maturation by activating a TAF(II)105-NF-kappaB-dependent transcription program. J Biol Chem. 2001; 276(29):27203-27206.
-
(2001)
J Biol Chem
, vol.276
, Issue.29
, pp. 27203-27206
-
-
Matza, D.1
Wolstein, O.2
Dikstein, R.3
Shachar, I.4
-
33
-
-
34848917110
-
CD74: a new candidate target for the immunotherapy of B-cell neoplasms
-
Stein R, Mattes MJ, Cardillo TM, Hansen HJ, Chang CH, Burton J, Govindan S, Goldenberg DM: CD74: a new candidate target for the immunotherapy of B-cell neoplasms. Clin Cancer Res. 2007; 13(18 Pt 2):5556s-5563s.
-
(2007)
Clin Cancer Res
, vol.13
, Issue.18 PART 2
-
-
Stein, R.1
Mattes, M.J.2
Cardillo, T.M.3
Hansen, H.J.4
Chang, C.H.5
Burton, J.6
Govindan, S.7
Goldenberg, D.M.8
-
34
-
-
79955974149
-
Combination anti-CD74 (milatuzumab) and anti-CD20 (rituximab) monoclonal antibody therapy has in vitro and in vivo activity in mantle cell lymphoma
-
Alinari L, Yu B, Christian BA, Yan F, Shin J, Lapalombella R, Hertlein E, Lustberg ME, Quinion C, Zhang X, Lozanski G, Muthusamy N, Praetorius-Ibba M, O'Connor OA, Goldenberg DM, Byrd JC et al: Combination anti-CD74 (milatuzumab) and anti-CD20 (rituximab) monoclonal antibody therapy has in vitro and in vivo activity in mantle cell lymphoma. Blood. 2011; 117(17):4530-4541.
-
(2011)
Blood
, vol.117
, Issue.17
, pp. 4530-4541
-
-
Alinari, L.1
Yu, B.2
Christian, B.A.3
Yan, F.4
Shin, J.5
Lapalombella, R.6
Hertlein, E.7
Lustberg, M.E.8
Quinion, C.9
Zhang, X.10
Lozanski, G.11
Muthusamy, N.12
Praetorius-Ibba, M.13
O'Connor, O.A.14
Goldenberg, D.M.15
Byrd, J.C.16
-
35
-
-
5144224056
-
Antiproliferative activity of a humanized anti-CD74 monoclonal antibody, hLL1, on B-cell malignancies
-
Stein R, Qu Z, Cardillo TM, Chen S, Rosario A, Horak ID, Hansen HJ, Goldenberg DM: Antiproliferative activity of a humanized anti-CD74 monoclonal antibody, hLL1, on B-cell malignancies. Blood. 2004; 104(12):3705-3711.
-
(2004)
Blood
, vol.104
, Issue.12
, pp. 3705-3711
-
-
Stein, R.1
Qu, Z.2
Cardillo, T.M.3
Chen, S.4
Rosario, A.5
Horak, I.D.6
Hansen, H.J.7
Goldenberg, D.M.8
-
36
-
-
0035525769
-
Complement-mediated cell death induced by rituximab in B-cell lymphoproliferative disorders is mediated in vitro by a caspase-independent mechanism involving the generation of reactive oxygen species
-
Bellosillo B, Villamor N, Lopez-Guillermo A, Marce S, Esteve J, Campo E, Colomer D, Montserrat E: Complement-mediated cell death induced by rituximab in B-cell lymphoproliferative disorders is mediated in vitro by a caspase-independent mechanism involving the generation of reactive oxygen species. Blood. 2001; 98(9):2771-2777.
-
(2001)
Blood
, vol.98
, Issue.9
, pp. 2771-2777
-
-
Bellosillo, B.1
Villamor, N.2
Lopez-Guillermo, A.3
Marce, S.4
Esteve, J.5
Campo, E.6
Colomer, D.7
Montserrat, E.8
-
37
-
-
76749146373
-
Dose-escalation trial of milatuzumab (humanized anti- CD74 monoclonal antibody) in multiple myeloma
-
Kaufman JL, Niesvizky R, Stadtmauer EA, Chanan-Khan A, Siegel D, Horne H, Teoh N, Wegener WA, Goldenberg DM: Dose-escalation trial of milatuzumab (humanized anti- CD74 monoclonal antibody) in multiple myeloma. ASCO Meeting Abstracts 2009, 27(15S):8593.
-
(2009)
ASCO Meeting Abstracts
, vol.27
, Issue.15 S
, pp. 8593
-
-
Kaufman, J.L.1
Niesvizky, R.2
Stadtmauer, E.A.3
Chanan-Khan, A.4
Siegel, D.5
Horne, H.6
Teoh, N.7
Wegener, W.A.8
Goldenberg, D.M.9
-
38
-
-
68849108368
-
Monoclonal antibodies directed to CD20 and HLA-DR can elicit homotypic adhesion followed by lysosome-mediated cell death in human lymphoma and leukemia cells
-
Ivanov A, Beers SA, Walshe CA, Honeychurch J, Alduaij W, Cox KL, Potter KN, Murray S, Chan CH, Klymenko T, Erenpreisa J, Glennie MJ, Illidge TM, Cragg MS: Monoclonal antibodies directed to CD20 and HLA-DR can elicit homotypic adhesion followed by lysosome-mediated cell death in human lymphoma and leukemia cells. J Clin Invest. 2009; 119(8):2143-2159.
-
(2009)
J Clin Invest
, vol.119
, Issue.8
, pp. 2143-2159
-
-
Ivanov, A.1
Beers, S.A.2
Walshe, C.A.3
Honeychurch, J.4
Alduaij, W.5
Cox, K.L.6
Potter, K.N.7
Murray, S.8
Chan, C.H.9
Klymenko, T.10
Erenpreisa, J.11
Glennie, M.J.12
Illidge, T.M.13
Cragg, M.S.14
-
39
-
-
79955979273
-
Novel type II anti- CD20 monoclonal antibody (GA101) evokes homotypic adhesion and actin-dependent, lysosome-mediated cell death in B-cell malignancies
-
Alduaij W, Ivanov A, Honeychurch J, Cheadle EJ, Potluri S, Lim SH, Shimada K, Chan CH, Tutt A, Beers SA, Glennie MJ, Cragg MS, Illidge TM: Novel type II anti- CD20 monoclonal antibody (GA101) evokes homotypic adhesion and actin-dependent, lysosome-mediated cell death in B-cell malignancies. Blood. 2011; 117(17):4519-4529.
-
(2011)
Blood
, vol.117
, Issue.17
, pp. 4519-4529
-
-
Alduaij, W.1
Ivanov, A.2
Honeychurch, J.3
Cheadle, E.J.4
Potluri, S.5
Lim, S.H.6
Shimada, K.7
Chan, C.H.8
Tutt, A.9
Beers, S.A.10
Glennie, M.J.11
Cragg, M.S.12
Illidge, T.M.13
-
40
-
-
28544435485
-
Lysosomes and autophagy in cell death control
-
Kroemer G, Jaattela M: Lysosomes and autophagy in cell death control. Nat Rev Cancer. 2005; 5(11):886-897.
-
(2005)
Nat Rev Cancer
, vol.5
, Issue.11
, pp. 886-897
-
-
Kroemer, G.1
Jaattela, M.2
-
41
-
-
76149140914
-
Oral fingolimod or intramuscular interferon for relapsing multiple sclerosis
-
Cohen JA, Barkhof F, Comi G, Hartung HP, Khatri BO, Montalban X, Pelletier J, Capra R, Gallo P, Izquierdo G, Tiel-Wilck K, de Vera A, Jin J, Stites T, Wu S, Aradhye S et al: Oral fingolimod or intramuscular interferon for relapsing multiple sclerosis. N Engl J Med. 2010; 362(5):402-415.
-
(2010)
N Engl J Med
, vol.362
, Issue.5
, pp. 402-415
-
-
Cohen, J.A.1
Barkhof, F.2
Comi, G.3
Hartung, H.P.4
Khatri, B.O.5
Montalban, X.6
Pelletier, J.7
Capra, R.8
Gallo, P.9
Izquierdo, G.10
Tiel-Wilck, K.11
de Vera, A.12
Jin, J.13
Stites, T.14
Wu, S.15
Aradhye, S.16
-
42
-
-
77953694847
-
FTY720 shows promising in vitro and in vivo preclinical activity by downmodulating Cyclin D1 and phospho-Akt in mantle cell lymphoma
-
Liu Q, Alinari L, Chen CS, Yan F, Dalton JT, Lapalombella R, Zhang X, Mani R, Lin T, Byrd JC, Baiocchi RA, Muthusamy N: FTY720 shows promising in vitro and in vivo preclinical activity by downmodulating Cyclin D1 and phospho-Akt in mantle cell lymphoma. Clin Cancer Res. 2010; 16(12):3182-3192.
-
(2010)
Clin Cancer Res
, vol.16
, Issue.12
, pp. 3182-3192
-
-
Liu, Q.1
Alinari, L.2
Chen, C.S.3
Yan, F.4
Dalton, J.T.5
Lapalombella, R.6
Zhang, X.7
Mani, R.8
Lin, T.9
Byrd, J.C.10
Baiocchi, R.A.11
Muthusamy, N.12
-
43
-
-
84255176452
-
FTY720 increases CD74 expression and sensitizes mantle cell lymphoma cells to milatuzumab-mediated cell death
-
Alinari L, Mahoney E, Patton J, Zhang X, Huynh L, Earl CT, Mani R, Mao Y, Yu B, Quinion C, Towns WH, Chen CS, Goldenberg DM, Blum KA, Byrd JC, Muthusamy N et al: FTY720 increases CD74 expression and sensitizes mantle cell lymphoma cells to milatuzumab-mediated cell death. Blood. 2011; 118(26):6893-6903.
-
(2011)
Blood
, vol.118
, Issue.26
, pp. 6893-6903
-
-
Alinari, L.1
Mahoney, E.2
Patton, J.3
Zhang, X.4
Huynh, L.5
Earl, C.T.6
Mani, R.7
Mao, Y.8
Yu, B.9
Quinion, C.10
Towns, W.H.11
Chen, C.S.12
Goldenberg, D.M.13
Blum, K.A.14
Byrd, J.C.15
Muthusamy, N.16
-
44
-
-
79957525337
-
Antitumor effects of OSU- 2S, a nonimmunosuppressive analogue of FTY720, in hepatocellular carcinoma
-
Omar HA, Chou CC, Berman-Booty LD, Ma Y, Hung JH, Wang D, Kogure T, Patel T, Terracciano L, Muthusamy N, Byrd JC, Kulp SK, Chen CS: Antitumor effects of OSU- 2S, a nonimmunosuppressive analogue of FTY720, in hepatocellular carcinoma. Hepatology. 2011; 53(6):1943-1958.
-
(2011)
Hepatology
, vol.53
, Issue.6
, pp. 1943-1958
-
-
Omar, H.A.1
Chou, C.C.2
Berman-Booty, L.D.3
Ma, Y.4
Hung, J.H.5
Wang, D.6
Kogure, T.7
Patel, T.8
Terracciano, L.9
Muthusamy, N.10
Byrd, J.C.11
Kulp, S.K.12
Chen, C.S.13
-
45
-
-
60849089338
-
Properties and structure-function relationships of veltuzumab (hA20), a humanized anti-CD20 monoclonal antibody
-
Goldenberg DM, Rossi EA, Stein R, Cardillo TM, Czuczman MS, Hernandez-Ilizaliturri FJ, Hansen HJ, Chang CH: Properties and structure-function relationships of veltuzumab (hA20), a humanized anti-CD20 monoclonal antibody. Blood. 2009; 113(5):1062-1070.
-
(2009)
Blood
, vol.113
, Issue.5
, pp. 1062-1070
-
-
Goldenberg, D.M.1
Rossi, E.A.2
Stein, R.3
Cardillo, T.M.4
Czuczman, M.S.5
Hernandez-Ilizaliturri, F.J.6
Hansen, H.J.7
Chang, C.H.8
-
46
-
-
77951829072
-
Veltuzumab (humanized anti-CD20 monoclonal antibody): characterization, current clinical results, and future prospects
-
Goldenberg DM, Morschhauser F, Wegener WA: Veltuzumab (humanized anti-CD20 monoclonal antibody): characterization, current clinical results, and future prospects. Leuk Lymphoma. 2010; 51(5):747-755.
-
(2010)
Leuk Lymphoma
, vol.51
, Issue.5
, pp. 747-755
-
-
Goldenberg, D.M.1
Morschhauser, F.2
Wegener, W.A.3
-
47
-
-
70249106098
-
Humanized anti- CD20 antibody, veltuzumab, in refractory/recurrent non- Hodgkin's lymphoma: phase I/II results
-
Morschhauser F, Leonard JP, Fayad L, Coiffier B, Petillon MO, Coleman M, Schuster SJ, Dyer MJ, Horne H, Teoh N, Wegener WA, Goldenberg DM: Humanized anti- CD20 antibody, veltuzumab, in refractory/recurrent non- Hodgkin's lymphoma: phase I/II results. J Clin Oncol. 2009; 27(20):3346-3353.
-
(2009)
J Clin Oncol
, vol.27
, Issue.20
, pp. 3346-3353
-
-
Morschhauser, F.1
Leonard, J.P.2
Fayad, L.3
Coiffier, B.4
Petillon, M.O.5
Coleman, M.6
Schuster, S.J.7
Dyer, M.J.8
Horne, H.9
Teoh, N.10
Wegener, W.A.11
Goldenberg, D.M.12
-
48
-
-
79953883456
-
Subcutaneous injections of low-dose veltuzumab (humanized anti-CD20 antibody) are safe and active in patients with indolent non-Hodgkin's lymphoma
-
Negrea GO, Elstrom R, Allen SL, Rai KR, Abbasi RM, Farber CM, Teoh N, Horne H, Wegener WA, Goldenberg DM: Subcutaneous injections of low-dose veltuzumab (humanized anti-CD20 antibody) are safe and active in patients with indolent non-Hodgkin's lymphoma. Haematologica. 2011; 96(4):567-573.
-
(2011)
Haematologica
, vol.96
, Issue.4
, pp. 567-573
-
-
Negrea, G.O.1
Elstrom, R.2
Allen, S.L.3
Rai, K.R.4
Abbasi, R.M.5
Farber, C.M.6
Teoh, N.7
Horne, H.8
Wegener, W.A.9
Goldenberg, D.M.10
-
49
-
-
84868334489
-
Results of A Phase I Study of Milatuzumab, a Humanized Anti-CD74 Antibody, and Veltuzumab, a Humanized Anti-CD20 Antibody In Patients with Relapsed and Refractory B-Cell Non-Hodgkin's Lymphoma
-
Christian B, Alinari L, Jones JA, Benson DM, Jr., Flynn JM, Porcu P, Lustberg ME, Phelps M, Poi M, Chung D, Quinion C, Byrd JC, Wegener W, Goldenberg DM, Baiocchi RA, Blum KA: Results of A Phase I Study of Milatuzumab, a Humanized Anti-CD74 Antibody, and Veltuzumab, a Humanized Anti-CD20 Antibody, In Patients with Relapsed and Refractory B-Cell Non-Hodgkin's Lymphoma. ASH Annual Meeting Abstracts. 2011; 118(21):3707.
-
(2011)
ASH Annual Meeting Abstracts
, vol.118
, Issue.21
, pp. 3707
-
-
Christian, B.1
Alinari, L.2
Jones, J.A.3
Benson Jr, D.M.4
Flynn, J.M.5
Porcu, P.6
Lustberg, M.E.7
Phelps, M.8
Poi, M.9
Chung, D.10
Quinion, C.11
Byrd, J.C.12
Wegener, W.13
Goldenberg, D.M.14
Baiocchi, R.A.15
Blum, K.A.16
-
50
-
-
2942567554
-
Prolonged treatment with rituximab in patients with follicular lymphoma significantly increases event-free survival and response duration compared with the standard weekly x 4 schedule
-
Ghielmini M, Schmitz SF, Cogliatti SB, Pichert G, Hummerjohann J, Waltzer U, Fey MF, Betticher DC, Martinelli G, Peccatori F, Hess U, Zucca E, Stupp R, Kovacsovics T, Helg C, Lohri A et al: Prolonged treatment with rituximab in patients with follicular lymphoma significantly increases event-free survival and response duration compared with the standard weekly x 4 schedule. Blood. 2004; 103(12):4416-4423.
-
(2004)
Blood
, vol.103
, Issue.12
, pp. 4416-4423
-
-
Ghielmini, M.1
Schmitz, S.F.2
Cogliatti, S.B.3
Pichert, G.4
Hummerjohann, J.5
Waltzer, U.6
Fey, M.F.7
Betticher, D.C.8
Martinelli, G.9
Peccatori, F.10
Hess, U.11
Zucca, E.12
Stupp, R.13
Kovacsovics, T.14
Helg, C.15
Lohri, A.16
-
51
-
-
27144497346
-
Single agent rituximab in patients with follicular or mantle cell lymphoma: clinical and biological factors that are predictive of response and event-free survival as well as the effect of rituximab on the immune system: a study of the Swiss Group for Clinical Cancer Research (SAKK)
-
Ghielmini M, Rufibach K, Salles G, Leoncini-Franscini L, Leger-Falandry C, Cogliatti S, Fey M, Martinelli G, Stahel R, Lohri A, Ketterer N, Wernli M, Cerny T, Schmitz SF: Single agent rituximab in patients with follicular or mantle cell lymphoma: clinical and biological factors that are predictive of response and event-free survival as well as the effect of rituximab on the immune system: a study of the Swiss Group for Clinical Cancer Research (SAKK). Ann Oncol. 2005; 16(10):1675-1682.
-
(2005)
Ann Oncol
, vol.16
, Issue.10
, pp. 1675-1682
-
-
Ghielmini, M.1
Rufibach, K.2
Salles, G.3
Leoncini-Franscini, L.4
Leger-Falandry, C.5
Cogliatti, S.6
Fey, M.7
Martinelli, G.8
Stahel, R.9
Lohri, A.10
Ketterer, N.11
Wernli, M.12
Cerny, T.13
Schmitz, S.F.14
-
52
-
-
77951047055
-
FLIPI Score Is Applicable and Predictive of Response to Upfront Immunotherapy in CALGB 50402 Phase II Trial of Extended Induction Galiximab ([G] anti-CD80 monoclonal antibody) Plus Rituximab [R]
-
Czuczman MS, Leonard JP, Johnson JL, Jung S-H, Hsi E, Byrd JC, Cheson BD: FLIPI Score Is Applicable and Predictive of Response to Upfront Immunotherapy in CALGB 50402: Phase II Trial of Extended Induction Galiximab ([G] anti-CD80 monoclonal antibody) Plus Rituximab [R]. ASH Annual Meeting Abstracts. 2008; 112(11):1003-.
-
(2008)
ASH Annual Meeting Abstracts
, vol.112
, Issue.11
, pp. 1003
-
-
Czuczman, M.S.1
Leonard, J.P.2
Johnson, J.L.3
Jung, S.-H.4
Hsi, E.5
Byrd, J.C.6
Cheson, B.D.7
-
53
-
-
20144385604
-
Chronic lymphocytic leukemia B cells contain anomalous Lyn tyrosine kinase, a putative contribution to defective apoptosis
-
Contri A, Brunati AM, Trentin L, Cabrelle A, Miorin M, Cesaro L, Pinna LA, Zambello R, Semenzato G, Donella- Deana A: Chronic lymphocytic leukemia B cells contain anomalous Lyn tyrosine kinase, a putative contribution to defective apoptosis. J Clin Invest. 2005; 115(2):369-378.
-
(2005)
J Clin Invest
, vol.115
, Issue.2
, pp. 369-378
-
-
Contri, A.1
Brunati, A.M.2
Trentin, L.3
Cabrelle, A.4
Miorin, M.5
Cesaro, L.6
Pinna, L.A.7
Zambello, R.8
Semenzato, G.9
Donella-Deana, A.10
-
54
-
-
77955625479
-
The Bruton tyrosine kinase inhibitor PCI-32765 blocks B-cell activation and is efficacious in models of autoimmune disease and B-cell malignancy
-
Honigberg LA, Smith AM, Sirisawad M, Verner E, Loury D, Chang B, Li S, Pan Z, Thamm DH, Miller RA, Buggy JJ: The Bruton tyrosine kinase inhibitor PCI-32765 blocks B-cell activation and is efficacious in models of autoimmune disease and B-cell malignancy. Proc Natl Acad Sci U S A. 2010; 107(29):13075-13080.
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, Issue.29
, pp. 13075-13080
-
-
Honigberg, L.A.1
Smith, A.M.2
Sirisawad, M.3
Verner, E.4
Loury, D.5
Chang, B.6
Li, S.7
Pan, Z.8
Thamm, D.H.9
Miller, R.A.10
Buggy, J.J.11
-
55
-
-
79959404661
-
Bruton tyrosine kinase represents a promising therapeutic target for treatment of chronic lymphocytic leukemia and is effectively targeted by PCI-32765
-
Herman SE, Gordon AL, Hertlein E, Ramanunni A, Zhang X, Jaglowski S, Flynn J, Jones J, Blum KA, Buggy JJ, Hamdy A, Johnson AJ, Byrd JC: Bruton tyrosine kinase represents a promising therapeutic target for treatment of chronic lymphocytic leukemia and is effectively targeted by PCI-32765. Blood. 2011; 117(23):6287-6296.
-
(2011)
Blood
, vol.117
, Issue.23
, pp. 6287-6296
-
-
Herman, S.E.1
Gordon, A.L.2
Hertlein, E.3
Ramanunni, A.4
Zhang, X.5
Jaglowski, S.6
Flynn, J.7
Jones, J.8
Blum, K.A.9
Buggy, J.J.10
Hamdy, A.11
Johnson, A.J.12
Byrd, J.C.13
-
56
-
-
78951491063
-
The Btk Inhibitor, PCI-32765 Induces Durable Responses with Minimal Toxicity In Patients with Relapsed/Refractory B-Cell Malignancies: Results From a Phase I Study
-
Fowler N, Sharman JP, Smith SM, Boyd T, Grant B, Kolibaba KS, Furman RR, Buggy J, Loury D, Hamdy A, Advani R: The Btk Inhibitor, PCI-32765, Induces Durable Responses with Minimal Toxicity In Patients with Relapsed/Refractory B-Cell Malignancies: Results From a Phase I Study. ASH Annual Meeting Abstracts. 2010; 116(21):964.
-
(2010)
ASH Annual Meeting Abstracts
, vol.116
, Issue.21
, pp. 964
-
-
Fowler, N.1
Sharman, J.P.2
Smith, S.M.3
Boyd, T.4
Grant, B.5
Kolibaba, K.S.6
Furman, R.R.7
Buggy, J.8
Loury, D.9
Hamdy, A.10
Advani, R.11
-
57
-
-
84860430028
-
The Bruton's Tyrosine Kinase Inhibitor PCI-32765 Is Highly Active As Single-Agent Therapy in Previously-Treated Mantle Cell Lymphoma (MCL): Preliminary Results of a Phase II Trial
-
Wang L, Martin P, Blum KA, Kahl BS, Maeda LS, Advani R, Williams ME, Rule S, Rodriguez S, Pang C-F, Hedrick E, Goy A: The Bruton's Tyrosine Kinase Inhibitor PCI-32765 Is Highly Active As Single-Agent Therapy in Previously-Treated Mantle Cell Lymphoma (MCL): Preliminary Results of a Phase II Trial. ASH Annual Meeting Abstracts. 2011; 118(21):442.
-
(2011)
ASH Annual Meeting Abstracts
, vol.118
, Issue.21
, pp. 442
-
-
Wang, L.1
Martin, P.2
Blum, K.A.3
Kahl, B.S.4
Maeda, L.S.5
Advani, R.6
Williams, M.E.7
Rule, S.8
Rodriguez, S.9
Pang, C.-F.10
Hedrick, E.11
Goy, A.12
-
58
-
-
0037205048
-
The phosphoinositide 3-kinase pathway
-
Cantley LC: The phosphoinositide 3-kinase pathway. Science. 2002; 296(5573):1655-1657.
-
(2002)
Science
, vol.296
, Issue.5573
, pp. 1655-1657
-
-
Cantley, L.C.1
-
59
-
-
0037352170
-
Involvement of PI3K/Akt pathway in cell cycle progression, apoptosis, and neoplastic transformation: a target for cancer chemotherapy
-
Chang F, Lee JT, Navolanic PM, Steelman LS, Shelton JG, Blalock WL, Franklin RA, McCubrey JA: Involvement of PI3K/Akt pathway in cell cycle progression, apoptosis, and neoplastic transformation: a target for cancer chemotherapy. Leukemia. 2003; 17(3):590-603.
-
(2003)
Leukemia
, vol.17
, Issue.3
, pp. 590-603
-
-
Chang, F.1
Lee, J.T.2
Navolanic, P.M.3
Steelman, L.S.4
Shelton, J.G.5
Blalock, W.L.6
Franklin, R.A.7
McCubrey, J.A.8
-
60
-
-
17144395975
-
The activation of Akt/PKB signaling pathway and cell survival
-
Song G, Ouyang G, Bao S: The activation of Akt/PKB signaling pathway and cell survival. J Cell Mol Med. 2005; 9(1):59-71.
-
(2005)
J Cell Mol Med
, vol.9
, Issue.1
, pp. 59-71
-
-
Song, G.1
Ouyang, G.2
Bao, S.3
-
61
-
-
32144446921
-
Expression of Akt (protein kinase B) and its isoforms in malignant lymphomas
-
Fillmore GC, Wang Q, Carey MJ, Kim CH, Elenitoba- Johnson KS, Lim MS: Expression of Akt (protein kinase B) and its isoforms in malignant lymphomas. Leuk Lymphoma. 2005; 46(12):1765-1773.
-
(2005)
Leuk Lymphoma
, vol.46
, Issue.12
, pp. 1765-1773
-
-
Fillmore, G.C.1
Wang, Q.2
Carey, M.J.3
Kim, C.H.4
Elenitoba-Johnson, K.S.5
Lim, M.S.6
-
62
-
-
0035437143
-
Altered apoptosis pathways in mantle cell lymphoma detected by oligonucleotide microarray
-
Hofmann WK, de Vos S, Tsukasaki K, Wachsman W, Pinkus GS, Said JW, Koeffler HP: Altered apoptosis pathways in mantle cell lymphoma detected by oligonucleotide microarray. Blood. 2001; 98(3):787-794.
-
(2001)
Blood
, vol.98
, Issue.3
, pp. 787-794
-
-
Hofmann, W.K.1
de Vos, S.2
Tsukasaki, K.3
Wachsman, W.4
Pinkus, G.S.5
Said, J.W.6
Koeffler, H.P.7
-
63
-
-
24944592507
-
Gene expression profiling of mantle cell lymphoma cells reveals aberrant expression of genes from the PI3K-AKT WNT and TGFbeta signalling pathways
-
Rizzatti EG, Falcao RP, Panepucci RA, Proto-Siqueira R, Anselmo-Lima WT, Okamoto OK, Zago MA: Gene expression profiling of mantle cell lymphoma cells reveals aberrant expression of genes from the PI3K-AKT, WNT and TGFbeta signalling pathways. Br J Haematol. 2005; 130(4):516-526.
-
(2005)
Br J Haematol
, vol.130
, Issue.4
, pp. 516-526
-
-
Rizzatti, E.G.1
Falcao, R.P.2
Panepucci, R.A.3
Proto-Siqueira, R.4
Anselmo-Lima, W.T.5
Okamoto, O.K.6
Zago, M.A.7
-
64
-
-
46749155539
-
Distinct functional significance of Akt and mTOR constitutive activation in mantle cell lymphoma
-
Dal Col J, Zancai P, Terrin L, Guidoboni M, Ponzoni M, Pavan A, Spina M, Bergamin S, Rizzo S, Tirelli U, De Rossi A, Doglioni C, Dolcetti R: Distinct functional significance of Akt and mTOR constitutive activation in mantle cell lymphoma. Blood. 2008; 111(10):5142-5151.
-
(2008)
Blood
, vol.111
, Issue.10
, pp. 5142-5151
-
-
Dal Col, J.1
Zancai, P.2
Terrin, L.3
Guidoboni, M.4
Ponzoni, M.5
Pavan, A.6
Spina, M.7
Bergamin, S.8
Rizzo, S.9
Tirelli, U.10
De Rossi, A.11
Doglioni, C.12
Dolcetti, R.13
-
65
-
-
38949178850
-
A phase II study of enzastaurin, a protein kinase C beta inhibitor, in patients with relapsed or refractory mantle cell lymphoma
-
Morschhauser F, Seymour JF, Kluin-Nelemans HC, Grigg A, Wolf M, Pfreundschuh M, Tilly H, Raemaekers J, van 't Veer MB, Milpied N, Cartron G, Pezzutto A, Spencer A, Reyes F, Dreyling M: A phase II study of enzastaurin, a protein kinase C beta inhibitor, in patients with relapsed or refractory mantle cell lymphoma. Ann Oncol. 2008; 19(2):247-253.
-
(2008)
Ann Oncol
, vol.19
, Issue.2
, pp. 247-253
-
-
Morschhauser, F.1
Seymour, J.F.2
Kluin-Nelemans, H.C.3
Grigg, A.4
Wolf, M.5
Pfreundschuh, M.6
Tilly, H.7
Raemaekers, J.8
van 't Veer, M.B.9
Milpied, N.10
Cartron, G.11
Pezzutto, A.12
Spencer, A.13
Reyes, F.14
Dreyling, M.15
-
66
-
-
77957196024
-
CAL-101, An Oral p110{delta} Selective Phosphatidylinositol-3-Kinase (PI3K) Inhibitor for the Treatment of B Cell Malignancies Inhibits PI3K Signaling Cellular Viability and Protective Signals of the Microenvironment
-
Lannutti BJ, Meadows SA, Kashishian A, Steiner B, Pogosov G, Sala-Torra O, Johnson AJ, Byrd JC, Radich J, Giese NA: CAL-101, An Oral p110{delta} Selective Phosphatidylinositol-3-Kinase (PI3K) Inhibitor for the Treatment of B Cell Malignancies Inhibits PI3K Signaling, Cellular Viability and Protective Signals of the Microenvironment. ASH Annual Meeting Abstracts. 2009; 114(22):286-.
-
(2009)
ASH Annual Meeting Abstracts
, vol.114
, Issue.22
, pp. 286
-
-
Lannutti, B.J.1
Meadows, S.A.2
Kashishian, A.3
Steiner, B.4
Pogosov, G.5
Sala-Torra, O.6
Johnson, A.J.7
Byrd, J.C.8
Radich, J.9
Giese, N.A.10
-
67
-
-
77957201023
-
Phosphatidylinositol 3-kinase-delta inhibitor CAL-101 shows promising preclinical activity in chronic lymphocytic leukemia by antagonizing intrinsic and extrinsic cellular survival signals
-
Herman SE, Gordon AL, Wagner AJ, Heerema NA, Zhao W, Flynn JM, Jones J, Andritsos L, Puri KD, Lannutti BJ, Giese NA, Zhang X, Wei L, Byrd JC, Johnson AJ: Phosphatidylinositol 3-kinase-delta inhibitor CAL-101 shows promising preclinical activity in chronic lymphocytic leukemia by antagonizing intrinsic and extrinsic cellular survival signals. Blood. 2010; 116(12):2078-2088.
-
(2010)
Blood
, vol.116
, Issue.12
, pp. 2078-2088
-
-
Herman, S.E.1
Gordon, A.L.2
Wagner, A.J.3
Heerema, N.A.4
Zhao, W.5
Flynn, J.M.6
Jones, J.7
Andritsos, L.8
Puri, K.D.9
Lannutti, B.J.10
Giese, N.A.11
Zhang, X.12
Wei, L.13
Byrd, J.C.14
Johnson, A.J.15
-
68
-
-
79958784935
-
Clinical Safety and Activity In a Phase 1 Study of CAL-101, An Isoform-Selective Inhibitor of Phosphatidylinositol 3-Kinase P110{delta} In Patients with Relapsed or Refractory Non-Hodgkin Lymphoma
-
Kahl B, Byrd JC, Flinn IW, Wagner-Johnston N, Spurgeon S, Benson DM, Jr, Furman RR, Brown JR, Coutre S, Lannutti B, Giese NA, Ulrich RG, Webb HK, Peterman S, Holes L, Yu AS: Clinical Safety and Activity In a Phase 1 Study of CAL-101, An Isoform-Selective Inhibitor of Phosphatidylinositol 3-Kinase P110{delta}, In Patients with Relapsed or Refractory Non-Hodgkin Lymphoma. ASH Annual Meeting Abstracts. 2010; 116(21):1777.
-
(2010)
ASH Annual Meeting Abstracts
, vol.116
, Issue.21
, pp. 1777
-
-
Kahl, B.1
Byrd, J.C.2
Flinn, I.W.3
Wagner-Johnston, N.4
Spurgeon, S.5
Benson, D.M.6
Furman, R.R.7
Brown, J.R.8
Coutre, S.9
Lannutti, B.10
Giese, N.A.11
Ulrich, R.G.12
Webb, H.K.13
Peterman, S.14
Holes, L.15
Yu, A.S.16
-
69
-
-
79959712087
-
Ras/Raf/MEK/ ERK and PI3K/PTEN/Akt/mTOR inhibitors: rationale and importance to inhibiting these pathways in human health
-
Chappell WH, Steelman LS, Long JM, Kempf RC, Abrams SL, Franklin RA, Basecke J, Stivala F, Donia M, Fagone P, Malaponte G, Mazzarino MC, Nicoletti F, Libra M, Maksimovic-Ivanic D, Mijatovic S et al: Ras/Raf/MEK/ ERK and PI3K/PTEN/Akt/mTOR inhibitors: rationale and importance to inhibiting these pathways in human health. Oncotarget. 2011; 2(3):135-164.
-
(2011)
Oncotarget
, vol.2
, Issue.3
, pp. 135-164
-
-
Chappell, W.H.1
Steelman, L.S.2
Long, J.M.3
Kempf, R.C.4
Abrams, S.L.5
Franklin, R.A.6
Basecke, J.7
Stivala, F.8
Donia, M.9
Fagone, P.10
Malaponte, G.11
Mazzarino, M.C.12
Nicoletti, F.13
Libra, M.14
Maksimovic-Ivanic, D.15
Mijatovic, S.16
-
70
-
-
79958011128
-
Role of dual PI3/Akt andmTOR inhibition in Waldenstrom's Macroglobulinemia
-
Sacco A, Roccaro A, Ghobrial IM: Role of dual PI3/Akt andmTOR inhibition in Waldenstrom's Macroglobulinemia. Oncotarget. 2010; 1(7):578-582.
-
(2010)
Oncotarget
, vol.1
, Issue.7
, pp. 578-582
-
-
Sacco, A.1
Roccaro, A.2
Ghobrial, I.M.3
-
71
-
-
79957984650
-
Refractory chronic lymphocytic leukemia-new therapeutic strategies
-
Schnaiter A, Stilgenbauer S: Refractory chronic lymphocytic leukemia-new therapeutic strategies. Oncotarget. 2010; 1(7):472-482.
-
(2010)
Oncotarget
, vol.1
, Issue.7
, pp. 472-482
-
-
Schnaiter, A.1
Stilgenbauer, S.2
-
72
-
-
23944481410
-
Phase II trial of single-agent temsirolimus (CCI-779) for relapsed mantle cell lymphoma
-
Witzig TE, Geyer SM, Ghobrial I, Inwards DJ, Fonseca R, Kurtin P, Ansell SM, Luyun R, Flynn PJ, Morton RF, Dakhil SR, Gross H, Kaufmann SH: Phase II trial of single-agent temsirolimus (CCI-779) for relapsed mantle cell lymphoma. J Clin Oncol. 2005; 23(23):5347-5356.
-
(2005)
J Clin Oncol
, vol.23
, Issue.23
, pp. 5347-5356
-
-
Witzig, T.E.1
Geyer, S.M.2
Ghobrial, I.3
Inwards, D.J.4
Fonseca, R.5
Kurtin, P.6
Ansell, S.M.7
Luyun, R.8
Flynn, P.J.9
Morton, R.F.10
Dakhil, S.R.11
Gross, H.12
Kaufmann, S.H.13
-
73
-
-
79751526328
-
A phase II trial of the oral mTOR inhibitor everolimus in relapsed aggressive lymphoma
-
Witzig TE, Reeder CB, LaPlant BR, Gupta M, Johnston PB, Micallef IN, Porrata LF, Ansell SM, Colgan JP, Jacobsen ED, Ghobrial IM, Habermann TM: A phase II trial of the oral mTOR inhibitor everolimus in relapsed aggressive lymphoma. Leukemia. 2011; 25(2):341-347.
-
(2011)
Leukemia
, vol.25
, Issue.2
, pp. 341-347
-
-
Witzig, T.E.1
Reeder, C.B.2
LaPlant, B.R.3
Gupta, M.4
Johnston, P.B.5
Micallef, I.N.6
Porrata, L.F.7
Ansell, S.M.8
Colgan, J.P.9
Jacobsen, E.D.10
Ghobrial, I.M.11
Habermann, T.M.12
-
74
-
-
49049087320
-
Low-dose, single-agent temsirolimus for relapsed mantle cell lymphoma: a phase 2 trial in the North Central Cancer Treatment Group
-
Ansell SM, Inwards DJ, Rowland KM, Jr., Flynn PJ, Morton RF, Moore DF, Jr., Kaufmann SH, Ghobrial I, Kurtin PJ, Maurer M, Allmer C, Witzig TE: Low-dose, single-agent temsirolimus for relapsed mantle cell lymphoma: a phase 2 trial in the North Central Cancer Treatment Group. Cancer. 2008; 113(3):508-514.
-
(2008)
Cancer
, vol.113
, Issue.3
, pp. 508-514
-
-
Ansell, S.M.1
Inwards, D.J.2
Rowland Jr, K.M.3
Flynn, P.J.4
Morton, R.F.5
Moore Jr, D.F.6
Kaufmann, S.H.7
Ghobrial, I.8
Kurtin, P.J.9
Maurer, M.10
Allmer, C.11
Witzig, T.E.12
-
75
-
-
68949102180
-
Phase III study to evaluate temsirolimus compared with investigator's choice therapy for the treatment of relapsed or refractory mantle cell lymphoma
-
Hess G, Herbrecht R, Romaguera J, Verhoef G, Crump M, Gisselbrecht C, Laurell A, Offner F, Strahs A, Berkenblit A, Hanushevsky O, Clancy J, Hewes B, Moore L, Coiffier B: Phase III study to evaluate temsirolimus compared with investigator's choice therapy for the treatment of relapsed or refractory mantle cell lymphoma. J Clin Oncol. 2009; 27(23):3822-3829.
-
(2009)
J Clin Oncol
, vol.27
, Issue.23
, pp. 3822-3829
-
-
Hess, G.1
Herbrecht, R.2
Romaguera, J.3
Verhoef, G.4
Crump, M.5
Gisselbrecht, C.6
Laurell, A.7
Offner, F.8
Strahs, A.9
Berkenblit, A.10
Hanushevsky, O.11
Clancy, J.12
Hewes, B.13
Moore, L.14
Coiffier, B.15
-
76
-
-
84863971730
-
A multicenter phase II trial (SAKK 36/06) of single-agent Everolimus(RAD001) in patients with relapsed or refractory mantle cell lymphoma
-
Feb 7. [Epub ahead of print]
-
Renner C, Zinzani P, Gressin R, Klingbiel D, Dietrich PY, Hitz F, Bargetzi M, Mingrone W, Martinelli G, Trojan A, Bouabdallah K, Lohri A, Gyan E, Biaggi C, Cogliatti S, Bertoni F et al: A multicenter phase II trial (SAKK 36/06) of single-agent Everolimus(RAD001) in patients with relapsed or refractory mantle cell lymphoma. Haematologica. 2012; Feb 7. [Epub ahead of print]
-
(2012)
Haematologica
-
-
Renner, C.1
Zinzani, P.2
Gressin, R.3
Klingbiel, D.4
Dietrich, P.Y.5
Hitz, F.6
Bargetzi, M.7
Mingrone, W.8
Martinelli, G.9
Trojan, A.10
Bouabdallah, K.11
Lohri, A.12
Gyan, E.13
Biaggi, C.14
Cogliatti, S.15
Bertoni, F.16
-
77
-
-
79953182631
-
Temsirolimus and rituximab in patients with relapsed or refractory mantle cell lymphoma: a phase 2 study
-
Ansell SM, Tang H, Kurtin PJ, Koenig PA, Inwards DJ, Shah K, Ziesmer SC, Feldman AL, Rao R, Gupta M, Erlichman C, Witzig TE: Temsirolimus and rituximab in patients with relapsed or refractory mantle cell lymphoma: a phase 2 study. Lancet Oncol. 2011; 12(4):361-368
-
(2011)
Lancet Oncol
, vol.12
, Issue.4
, pp. 361-368
-
-
Ansell, S.M.1
Tang, H.2
Kurtin, P.J.3
Koenig, P.A.4
Inwards, D.J.5
Shah, K.6
Ziesmer, S.C.7
Feldman, A.L.8
Rao, R.9
Gupta, M.10
Erlichman, C.11
Witzig, T.E.12
|