-
1
-
-
78249261016
-
Accumulation of driver and passenger mutations during tumor progression
-
PMID:20876136
-
Bozic I, Antal T, Ohtsuki H, Carter H, Kim D, Chen S, et al. Accumulation of driver and passenger mutations during tumor progression. Proc Natl Acad Sci USA 2010; 107:18545-50; PMID:20876136; http://dx.doi.org/10.1073/pnas. 1010978107.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 18545-18550
-
-
Bozic, I.1
Antal, T.2
Ohtsuki, H.3
Carter, H.4
Kim, D.5
Chen, S.6
-
2
-
-
52149123619
-
Core signaling pathways in human pancreatic cancers revealed by global genomic analyses
-
PMID:18772397
-
Jones S, Zhang X, Parsons DW, Lin JC, Leary RJ, Angenendt P, et al. Core signaling pathways in human pancreatic cancers revealed by global genomic analyses. Science 2008; 321:1801-6; PMID:18772397; http://dx.doi.org/10.1126/ science.1164368.
-
(2008)
Science
, vol.321
, pp. 1801-1806
-
-
Jones, S.1
Zhang, X.2
Parsons, D.W.3
Lin, J.C.4
Leary, R.J.5
Angenendt, P.6
-
3
-
-
36248962105
-
The genomic landscapes of human breast and colorectal cancers
-
PMID:17932254
-
Wood LD, Parsons DW, Jones S, Lin J, Sjöblom T, Leary RJ, et al. The genomic landscapes of human breast and colorectal cancers. Science 2007; 318:1108-13; PMID:17932254; http://dx.doi.org/10.1126/science.1145720.
-
(2007)
Science
, vol.318
, pp. 1108-1113
-
-
Wood, L.D.1
Parsons, D.W.2
Jones, S.3
Lin, J.4
Sjöblom, T.5
Leary, R.J.6
-
4
-
-
0038488950
-
A multigenic program mediating breast cancer metastasis to bone
-
PMID:12842083
-
Kang Y, Siegel PM, Shu W, Drobnjak M, Kakonen SM, Cordón-Cardo C, et al. A multigenic program mediating breast cancer metastasis to bone. Cancer Cell 2003; 3:537-49; PMID:12842083; http://dx.doi.org/10.1016/S1535-6108(03) 00132-6.
-
(2003)
Cancer Cell
, vol.3
, pp. 537-549
-
-
Kang, Y.1
Siegel, P.M.2
Shu, W.3
Drobnjak, M.4
Kakonen, S.M.5
Cordón-Cardo, C.6
-
5
-
-
23144461051
-
Genes that mediate breast cancer metastasis to lung
-
PMID:16049480
-
Minn AJ, Gupta GP, Siegel PM, Bos PD, Shu W, Giri DD, et al. Genes that mediate breast cancer metastasis to lung. Nature 2005; 436:518-24; PMID:16049480;http://dx.doi.org/10.1038/nature03799.
-
(2005)
Nature
, vol.436
, pp. 518-524
-
-
Minn, A.J.1
Gupta, G.P.2
Siegel, P.M.3
Bos, P.D.4
Shu, W.5
Giri, D.D.6
-
6
-
-
34147220392
-
Mediators of vascular remodelling co-opted for sequential steps in lung metastasis
-
PMID:17429393
-
Gupta GP, Nguyen DX, Chiang AC, Bos PD, Kim JY, Nadal C, et al. Mediators of vascular remodelling co-opted for sequential steps in lung metastasis. Nature 2007; 446:765-70; PMID:17429393; http://dx.doi.org/10.1038/nature05760.
-
(2007)
Nature
, vol.446
, pp. 765-770
-
-
Gupta, G.P.1
Nguyen, D.X.2
Chiang, A.C.3
Bos, P.D.4
Kim, J.Y.5
Nadal, C.6
-
7
-
-
37649001973
-
ID genes mediate tumor reinitiation during breast cancer lung metastasis
-
PMID:18048329
-
Gupta GP, Perk J, Acharyya S, de Candia P, Mittal V, Todorova-Manova K, et al. ID genes mediate tumor reinitiation during breast cancer lung metastasis. Proc Natl Acad Sci USA 2007; 104:19506-11; PMID:18048329; http://dx.doi.org/10. 1073/pnas.0709185104.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 19506-19511
-
-
Gupta, G.P.1
Perk, J.2
Acharyya, S.3
De Candia, P.4
Mittal, V.5
Todorova-Manova, K.6
-
8
-
-
79960117895
-
Breast cancer cells produce tenascin C as a metastatic niche component to colonize the lungs
-
PMID:21706029
-
Oskarsson T, Acharyya S, Zhang XH, Vanharanta S, Tavazoie SF, Morris PG, et al. Breast cancer cells produce tenascin C as a metastatic niche component to colonize the lungs. Nat Med 2011; 17:867-74; PMID:21706029; http://dx.doi.org/10.1038/nm.2379.
-
(2011)
Nat Med
, vol.17
, pp. 867-874
-
-
Oskarsson, T.1
Acharyya, S.2
Zhang, X.H.3
Vanharanta, S.4
Tavazoie, S.F.5
Morris, P.G.6
-
9
-
-
80054725681
-
Macrophage binding to receptor VCAM-1 transmits survival signals in breast cancer cells that invade the lungs
-
PMID:22014578
-
Chen Q, Zhang XH, Massagué J. Macrophage binding to receptor VCAM-1 transmits survival signals in breast cancer cells that invade the lungs. Cancer Cell 2011; 20:538-49; PMID:22014578; http://dx.doi.org/10.1016/j.ccr. 2011.08.025.
-
(2011)
Cancer Cell
, vol.20
, pp. 538-549
-
-
Chen, Q.1
Zhang, X.H.2
Massagué, J.3
-
10
-
-
40749094918
-
SATB1 reprogrammes gene expression to promote breast tumour growth and metastasis
-
PMID:18337816
-
Han HJ, Russo J, Kohwi Y, Kohwi-Shigematsu T. SATB1 reprogrammes gene expression to promote breast tumour growth and metastasis. Nature 2008; 452:187-93; PMID:18337816; http://dx.doi.org/10.1038/nature06781.
-
(2008)
Nature
, vol.452
, pp. 187-193
-
-
Han, H.J.1
Russo, J.2
Kohwi, Y.3
Kohwi-Shigematsu, T.4
-
11
-
-
38049115129
-
Endogenous human microRNAs that suppress breast cancer metastasis
-
PMID:18185580
-
Tavazoie SF, Alarcón C, Oskarsson T, Padua D, Wang Q, Bos PD, et al. Endogenous human microRNAs that suppress breast cancer metastasis. Nature 2008; 451:147-52; PMID:18185580; http://dx.doi.org/10.1038/nature06487.
-
(2008)
Nature
, vol.451
, pp. 147-152
-
-
Tavazoie, S.F.1
Alarcón, C.2
Oskarsson, T.3
Padua, D.4
Wang, Q.5
Bos, P.D.6
-
12
-
-
77951118936
-
Long non-coding RNA HOTAIR reprograms chromatin state to promote cancer metastasis
-
PMID:20393566
-
Gupta RA, Shah N, Wang KC, Kim J, Horlings HM, Wong DJ, et al. Long non-coding RNA HOTAIR reprograms chromatin state to promote cancer metastasis. Nature 2010; 464:1071-6; PMID:20393566;http://dx.doi.org/10.1038/nature08975.
-
(2010)
Nature
, vol.464
, pp. 1071-1076
-
-
Gupta, R.A.1
Shah, N.2
Wang, K.C.3
Kim, J.4
Horlings, H.M.5
Wong, D.J.6
-
13
-
-
49849091679
-
Micromanagers of malignancy: Role of microRNAs in regulating metastasis
-
PMID:18674843
-
Ma L, Weinberg RA. Micromanagers of malignancy: role of microRNAs in regulating metastasis. Trends Genet 2008; 24:448-56; PMID:18674843; http://dx.doi.org/10.1016/j.tig.2008.06.004.
-
(2008)
Trends Genet
, vol.24
, pp. 448-456
-
-
Ma, L.1
Weinberg, R.A.2
-
14
-
-
67649662201
-
WNT/TCF signaling through LEF1 and HOXB9 mediates lung adenocarcinoma metastasis
-
PMID:19576624
-
Nguyen DX, Chiang AC, Zhang XH, Kim JY, Kris MG, Ladanyi M, et al. WNT/TCF signaling through LEF1 and HOXB9 mediates lung adenocarcinoma metastasis. Cell 2009; 138:51-62; PMID:19576624;http://dx.doi.org/10.1016/j. cell.2009.04.030.
-
(2009)
Cell
, vol.138
, pp. 51-62
-
-
Nguyen, D.X.1
Chiang, A.C.2
Zhang, X.H.3
Kim, J.Y.4
Kris, M.G.5
Ladanyi, M.6
-
15
-
-
66449095667
-
A pleiotropically acting microRNA, miR-31, inhibits breast cancer metastasis
-
PMID:19524507
-
Valastyan S, Reinhardt F, Benaich N, Calogrias D, Szász AM, Wang ZC, et al. A pleiotropically acting microRNA, miR-31, inhibits breast cancer metastasis. Cell 2009; 137:1032-46; PMID:19524507; http://dx.doi.org/10.1016/j. cell.2009.03.047.
-
(2009)
Cell
, vol.137
, pp. 1032-1046
-
-
Valastyan, S.1
Reinhardt, F.2
Benaich, N.3
Calogrias, D.4
Szász, A.M.5
Wang, Z.C.6
-
16
-
-
67649311599
-
Latent bone metastasis in breast cancer tied to Src-dependent survival signals
-
PMID:19573813
-
Zhang XH, Wang Q, Gerald W, Hudis CA, Norton L, Smid M, et al. Latent bone metastasis in breast cancer tied to Src-dependent survival signals. Cancer Cell 2009; 16:67-78; PMID:19573813; http://dx.doi.org/10.1016/j.ccr.2009.05.017.
-
(2009)
Cancer Cell
, vol.16
, pp. 67-78
-
-
Zhang, X.H.1
Wang, Q.2
Gerald, W.3
Hudis, C.A.4
Norton, L.5
Smid, M.6
-
17
-
-
27344435774
-
Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles
-
PMID:16199517
-
Subramanian A, Tamayo P, Mootha VK, Mukherjee S, Ebert BL, Gillette MA, et al. Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles. Proc Natl Acad Sci USA 2005; 102:15545-50; PMID:16199517; http://dx.doi.org/10.1073/pnas.0506580102.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 15545-15550
-
-
Subramanian, A.1
Tamayo, P.2
Mootha, V.K.3
Mukherjee, S.4
Ebert, B.L.5
Gillette, M.A.6
-
18
-
-
77958570788
-
Inferring regulatory networks from expression data using tree-based methods
-
PMID:20927193
-
Huynh-Thu VA, Irrthum A, Wehenkel L, Geurts P. Inferring regulatory networks from expression data using tree-based methods. PLoS ONE 2010; 5:12776;PMID:20927193; http://dx.doi.org/10.1371/journal.pone.0012776.
-
(2010)
PLoS ONE
, vol.5
, pp. 12776
-
-
Huynh-Thu, V.A.1
Irrthum, A.2
Wehenkel, L.3
Geurts, P.4
-
19
-
-
79952659846
-
Boosting signal-tonoise in complex biology: Prior knowledge is power
-
PMID:21414478
-
Ideker T, Dutkowski J, Hood L. Boosting signal-tonoise in complex biology: prior knowledge is power. Cell 2011; 144:860-3; PMID:21414478; http://dx.doi.org/10.1016/j.cell.2011.03.007.
-
(2011)
Cell
, vol.144
, pp. 860-863
-
-
Ideker, T.1
Dutkowski, J.2
Hood, L.3
-
20
-
-
35348890683
-
On testing the significance of sets of genes
-
Efron B, Tibshirani R. On testing the significance of sets of genes. Annals of Applied Statistics 2007; 1:107-29; http://dx.doi.org/10.1214/07- AOAS101.
-
(2007)
Annals of Applied Statistics
, vol.1
, pp. 107-129
-
-
Efron, B.1
Tibshirani, R.2
-
21
-
-
0035478854
-
Random Forests
-
Breiman L. Random Forests. Mach Learn 2001; 45:5-32; http://dx.doi.org/ 10.1023/A:1010933404324.
-
(2001)
Mach Learn
, vol.45
, pp. 5-32
-
-
Breiman, L.1
-
22
-
-
60549104367
-
Raf kinase inhibitory protein suppresses a metastasis signalling cascade involving LIN28 and let-7
-
PMID:19153603
-
Dangi-Garimella S, Yun J, Eves EM, Newman M, Erkeland SJ, Hammond SM, et al. Raf kinase inhibitory protein suppresses a metastasis signalling cascade involving LIN28 and let-7. EMBO J 2009; 28:347-58; PMID:19153603; http://dx.doi.org/10.1038/emboj.2008.294.
-
(2009)
EMBO J
, vol.28
, pp. 347-358
-
-
Dangi-Garimella, S.1
Yun, J.2
Eves, E.M.3
Newman, M.4
Erkeland, S.J.5
Hammond, S.M.6
-
23
-
-
41849102400
-
Raf kinase inhibitory protein: A signal transduction modulator and metastasis suppressor
-
PMID:18379591
-
Granovsky AE, Rosner MR. Raf kinase inhibitory protein: a signal transduction modulator and metastasis suppressor. Cell Res 2008; 18:452-7; PMID:18379591;http://dx.doi.org/10.1038/cr.2008.43.
-
(2008)
Cell Res
, vol.18
, pp. 452-457
-
-
Granovsky, A.E.1
Rosner, M.R.2
-
24
-
-
0037631323
-
Activation of Raf-1 signaling by protein kinase C through a mechanism involving Raf kinase inhibitory protein
-
PMID:12551925
-
Corbit KC, Trakul N, Eves EM, Diaz B, Marshall M, Rosner MR. Activation of Raf-1 signaling by protein kinase C through a mechanism involving Raf kinase inhibitory protein. J Biol Chem 2003; 278:13061-8; PMID:12551925; http://dx.doi.org/10.1074/jbc.M210015200.
-
(2003)
J Biol Chem
, vol.278
, pp. 13061-13068
-
-
Corbit, K.C.1
Trakul, N.2
Eves, E.M.3
Diaz, B.4
Marshall, M.5
Rosner, M.R.6
-
25
-
-
21644484717
-
Raf kinase inhibitory protein regulates Raf-1 but not B-Raf kinase activation
-
PMID:15886202
-
Trakul N, Menard RE, Schade GR, Qian Z, Rosner MR. Raf kinase inhibitory protein regulates Raf-1 but not B-Raf kinase activation. J Biol Chem 2005;280:24931-40; PMID:15886202; http://dx.doi.org/10.1074/jbc.M413929200.
-
(2005)
J Biol Chem
, vol.280
, pp. 24931-24940
-
-
Trakul, N.1
Menard, R.E.2
Schade, G.R.3
Qian, Z.4
Rosner, M.R.5
-
26
-
-
0346874333
-
Protein kinase C switches the Raf kinase inhibitor from Raf-1 to GRK-2
-
PMID:14654844
-
Lorenz K, Lohse MJ, Quitterer U. Protein kinase C switches the Raf kinase inhibitor from Raf-1 to GRK-2. Nature 2003; 426:574-9; PMID:14654844; http://dx.doi.org/10.1038/nature02158.
-
(2003)
Nature
, vol.426
, pp. 574-579
-
-
Lorenz, K.1
Lohse, M.J.2
Quitterer, U.3
-
27
-
-
0034791116
-
Raf kinase inhibitor protein interacts with NFkappaB-inducing kinase and TAK1 and inhibits NFkappaB activation
-
PMID:11585904
-
Yeung KC, Rose DW, Dhillon AS, Yaros D, Gustafsson M, Chatterjee D, et al. Raf kinase inhibitor protein interacts with NFkappaB-inducing kinase and TAK1 and inhibits NFkappaB activation. Mol Cell Biol 2001; 21:7207-17; PMID:11585904; http://dx.doi.org/10.1128/MCB.21.21.7207-17.2001.
-
(2001)
Mol Cell Biol
, vol.21
, pp. 7207-7217
-
-
Yeung, K.C.1
Rose, D.W.2
Dhillon, A.S.3
Yaros, D.4
Gustafsson, M.5
Chatterjee, D.6
-
28
-
-
33746942671
-
Raf kinase inhibitory protein regulates aurora B kinase and the spindle checkpoint
-
PMID:16916643
-
Eves EM, Shapiro P, Naik K, Klein UR, Trakul N, Rosner MR. Raf kinase inhibitory protein regulates aurora B kinase and the spindle checkpoint. Mol Cell 2006; 23:561-74; PMID:16916643; http://dx.doi.org/10.1016/j.molcel.2006.07. 015.
-
(2006)
Mol Cell
, vol.23
, pp. 561-574
-
-
Eves, E.M.1
Shapiro, P.2
Naik, K.3
Klein, U.R.4
Trakul, N.5
Rosner, M.R.6
-
29
-
-
33845925740
-
Growth-suppressive function of phosphatidylethanolamine-binding protein in anaplastic thyroid cancer
-
PMID:17201166
-
Akaishi J, Onda M, Asaka S, Okamoto J, Miyamoto S, Nagahama M, et al. Growth-suppressive function of phosphatidylethanolamine-binding protein in anaplastic thyroid cancer. Anticancer Res 2006; 26:4437-42;PMID:17201166.
-
(2006)
Anticancer Res
, vol.26
, pp. 4437-4442
-
-
Akaishi, J.1
Onda, M.2
Asaka, S.3
Okamoto, J.4
Miyamoto, S.5
Nagahama, M.6
-
30
-
-
34247333383
-
Raf kinase inhibitor protein expression in a survival analysis of colorectal cancer patients
-
PMID:17179102
-
Al-Mulla F, Hagan S, Behbehani AI, Bitar MS, George SS, Going JJ, et al. Raf kinase inhibitor protein expression in a survival analysis of colorectal cancer patients. J Clin Oncol 2006; 24:5672-9; PMID:17179102;http://dx.doi.org/ 10.1200/JCO.2006.07.5499.
-
(2006)
J Clin Oncol
, vol.24
, pp. 5672-5679
-
-
Al-Mulla, F.1
Hagan, S.2
Behbehani, A.I.3
Bitar, M.S.4
George, S.S.5
Going, J.J.6
-
31
-
-
31944443578
-
Metastasis suppressor gene Raf kinase inhibitor protein (RKIP) is a novel prognostic marker in prostate cancer
-
PMID:16175585
-
Fu Z, Kitagawa Y, Shen R, Shah R, Mehra R, Rhodes D, et al. Metastasis suppressor gene Raf kinase inhibitor protein (RKIP) is a novel prognostic marker in prostate cancer. Prostate 2006; 66:248-56; PMID:16175585;http://dx.doi.org/ 10.1002/pros.20319.
-
(2006)
Prostate
, vol.66
, pp. 248-256
-
-
Fu, Z.1
Kitagawa, Y.2
Shen, R.3
Shah, R.4
Mehra, R.5
Rhodes, D.6
-
32
-
-
0038275924
-
Effects of raf kinase inhibitor protein expression on suppression of prostate cancer metastasis
-
PMID:12813171
-
Fu Z, Smith PC, Zhang L, Rubin MA, Dunn RL, Yao Z, et al. Effects of raf kinase inhibitor protein expression on suppression of prostate cancer metastasis. J Natl Cancer Inst 2003; 95:878-89; PMID:12813171;http://dx.doi.org/ 10.1093/jnci/95.12.878.
-
(2003)
J Natl Cancer Inst
, vol.95
, pp. 878-889
-
-
Fu, Z.1
Smith, P.C.2
Zhang, L.3
Rubin, M.A.4
Dunn, R.L.5
Yao, Z.6
-
33
-
-
27144473329
-
Reduction of Raf-1 kinase inhibitor protein expression correlates with breast cancer metastasis
-
PMID:16243812
-
Hagan S, Al-Mulla F, Mallon E, Oien K, Ferrier R, Gusterson B, et al. Reduction of Raf-1 kinase inhibitor protein expression correlates with breast cancer metastasis. Clin Cancer Res 2005; 11:7392-7;PMID:16243812; http://dx.doi.org/10.1158/1078-0432.CCR-05-0283.
-
(2005)
Clin Cancer Res
, vol.11
, pp. 7392-7397
-
-
Hagan, S.1
Al-Mulla, F.2
Mallon, E.3
Oien, K.4
Ferrier, R.5
Gusterson, B.6
-
34
-
-
3442883359
-
Reduction in Raf kinase inhibitor protein expression is associated with increased Ras-extracellular signal-regulated kinase signaling in melanoma cell lines
-
PMID:15289323
-
Schuierer MM, Bataille F, Hagan S, Kolch W, Bosserhoff AK. Reduction in Raf kinase inhibitor protein expression is associated with increased Ras-extracellular signal-regulated kinase signaling in melanoma cell lines. Cancer Res 2004; 64:5186-92;PMID:15289323; http://dx.doi.org/10.1158/0008-5472. CAN-03-3861.
-
(2004)
Cancer Res
, vol.64
, pp. 5186-5192
-
-
Schuierer, M.M.1
Bataille, F.2
Hagan, S.3
Kolch, W.4
Bosserhoff, A.K.5
-
35
-
-
80455174648
-
Signalling pathway for RKIP and Let-7 regulates and predicts metastatic breast cancer
-
PMID:21873975
-
Yun J, Frankenberger CA, Kuo WL, Boelens MC, Eves EM, Cheng N, et al. Signalling pathway for RKIP and Let-7 regulates and predicts metastatic breast cancer. EMBO J 2011; 30:4500-14; PMID:21873975; http://dx.doi.org/10.1038/emboj. 2011.312.
-
(2011)
EMBO J
, vol.30
, pp. 4500-4514
-
-
Yun, J.1
Frankenberger, C.A.2
Kuo, W.L.3
Boelens, M.C.4
Eves, E.M.5
Cheng, N.6
-
36
-
-
36849023466
-
Let-7 prevents early cancer progression by suppressing expression of the embryonic gene HMGA2
-
PMID:17957144
-
Park SM, Shell S, Radjabi AR, Schickel R, Feig C, Boyerinas B, et al. Let-7 prevents early cancer progression by suppressing expression of the embryonic gene HMGA2. Cell Cycle 2007; 6:2585-90;PMID:17957144; http://dx.doi.org/10.4161/cc.6.21.4845.
-
(2007)
Cell Cycle
, vol.6
, pp. 2585-2590
-
-
Park, S.M.1
Shell, S.2
Radjabi, A.R.3
Schickel, R.4
Feig, C.5
Boyerinas, B.6
-
37
-
-
84863799255
-
RKIP Suppresses Breast Cancer Metastasis to the Bone by Regulating Stroma-Associated Genes
-
PMID:22482058
-
Bevilacqua E, Frankenberger CA, Rosner MR. RKIP Suppresses Breast Cancer Metastasis to the Bone by Regulating Stroma-Associated Genes. Int J Breast Cancer 2012; 2012:124704; PMID:22482058; http://dx.doi.org/10.1155/2012/124704.
-
(2012)
Int J Breast Cancer
, vol.2012
, pp. 124704
-
-
Bevilacqua, E.1
Frankenberger, C.A.2
Rosner, M.R.3
|