Rapid isolation of viable circulating tumor cells from patient blood samples

Journal of Visualized Experiments

Volumn , Issue 64, 2012, Pages

  Hughes, Andrew D ^a   Mattison, Jeff ^a   Powderly, John D ^b,c   Greene, Bryan T ^b,c   King, Michael R ^a  

^a School of Operations Research and Industrial Engineering   (United States)

^b BioCytics Inc   (United States)

^c PLLC   (United States)

Author keywords

Bioengineering; Biomedical engineering; Cancer; Cancer biology; Cell isolation; Circulating tumor cells; Halloysite nanotubes; Issue 64; Metastasis; Nanotechnology; Selectin

Indexed keywords

EID: 84863805548     PISSN: 1940087X     EISSN: None     Source Type: Journal    
DOI: 10.3791/4248     Document Type: Article

References (11)

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2. Hughes, A.D. & King, M.R. Nanobiotechnology for the capture and manipulation of circulating tumor cells. Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology., doi:10.1002/wnan.168 (2011).
3. Hughes, A.D., et al. Microtube Device for Selectin-Mediated Capture of Viable Circulating Tumor Cells from Blood. Clinical Chemistry. 58, 846-853, doi: 10.1373/clinchem.2011.176669 (2012).
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8. Lee, D. & King, M.R. Microcontact Printing of P-Selectin Increases the Rate of Neutrophil Recruitment Under Shear Flow. Biotechnology Progress. 24, 1052-1059, doi:10.1021/Bp.35 (2008).
9. Gout, S., Tremblay, P.L., & Huot, J. Selectins and selectin ligands in extravasation of cancer cells and organ selectivity of metastasis. Clin. Exp. Metastasis. 25, 335-344, doi:10.1007/s10585-007-9096-4 (2008).
10. Geng, Y., Marshall, J., & King, M. Glycomechanics of the Metastatic Cascade: Tumor Cell-Endothelial Cell Interactions in the Circulation. Annals of Biomedical Engineering., 1-16, doi:10.1007/s10439-011-0463-6.
11. Stott, S.L., et al. Isolation of circulating tumor cells using a microvortex-generating herringbone-chip. Proc. Natl. Acad. Sci. U.S.A. 107, 18392-18397, doi:10.1073/pnas.1012539107 [pii] 1012539107 (2010).