Meta-analysis of the association between the interleukin-1A -889C/T polymorphism and Alzheimer's disease

Journal of Neuroscience Research

Volumn 90, Issue 9, 2012, Pages 1681-1692

  Hua, Ye ^a   Zhao, Hui ^a   Kong, Yuenan ^a   Lu, Xiaojie ^a  

^a NANJING MEDICAL UNIVERSITY   (China)

Author keywords

Gene polymorphism; Interleukin 1A; Meta analysis, Alzheimer's disease

Indexed keywords

INTERLEUKIN 1ALPHA;

ALZHEIMER DISEASE; ASIAN; CAUCASIAN; DNA POLYMORPHISM; ETHNICITY; GENE FREQUENCY; GENETIC ASSOCIATION; GENETIC RISK; GENETIC SUSCEPTIBILITY; GENOTYPE; HETEROZYGOTE; HOMOZYGOTE; HUMAN; META ANALYSIS; PRIORITY JOURNAL; REVIEW;

AGE OF ONSET; ALZHEIMER DISEASE; ASIAN CONTINENTAL ANCESTRY GROUP; EUROPEAN CONTINENTAL ANCESTRY GROUP; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HUMANS; INTERLEUKIN-1ALPHA; POLYMORPHISM, SINGLE NUCLEOTIDE;

EID: 84863783782     PISSN: 03604012     EISSN: 10974547     Source Type: Journal    
DOI: 10.1002/jnr.23062     Document Type: Review

References (47)

1. Akiyama H, Barger S, Barnum S, Bradt B, Bauer J, Cole GM, et al. 2000. Inflammation and Alzheimer's disease. Neurobiol Aging 21: 383-421.
2. Bird TD. 2008. Genetic aspects of Alzheimer disease. Genet Med 10: 231-239.
3. Blasko I, Marx F, Steiner E, Hartmann T, Grubeck-Loebenstein B. 1999. TNFalpha plus IFNgamma induce the production of Alzheimer beta-amyloid peptides and decrease the secretion of APPs. FASEB J 13: 63-68.
4. Bosco P, Gueant-Rodriguez RM, Anello G, Romano A, Namour B, Spada RS, et al. 2004. Association of IL-1 RN*2 allele and methionine synthase 2756AA genotype with dementia severity of sporadic Alzheimer's disease. J Neurol Neurosurg Psychiatry 75: 1036-1038.
5. Campion D, Dumanchin C, Hannequin D, Dubois B, Belliard S, Puel M, et al. 1999. Early-onset autosomal dominant Alzheimer disease: prevalence, genetic heterogeneity, and mutation spectrum. Am J Hum Genet 65: 664-670.
6. Clarimon J, Bertranpetit J, Calafell F, Boada M, Tarraga L, Comas D. 2003. Joint analysis of candidate genes related to Alzheimer's disease in a Spanish population. Psychiatr Genet 13: 85-90.
7. Combarros O, Sanchez-Guerra M, Infante J, Llorca J, Berciano J. 2002. Gene dose-dependent association of interleukin-1A [-889] allele polymorphism with Alzheimer's disease. J Neurol 249: 1242-1245.
8. Cousin E, Mace S, Rocher C, Dib C, Muzard G, Hannequin D, et al. 2011. No replication of genetic association between candidate polymorphisms and Alzheimer's disease. Neurobiol Aging 32: 1443-1451.
9. Culpan D, Prince JA, Matthews S, Palmer L, Hughes A, Love S, et al. 2006. Neither sequence variation in the IL-10 gene promoter nor presence of IL-10 protein in the cerebral cortex is associated with Alzheimer's disease. Neurosci Lett 408: 141-145.
10. Deniz-Naranjo MC, Munoz-Fernandez C, Alemany-Rodriguez MJ, Perez-Vieitez MC, Aladro-Benito Y, Irurita-Latasa J, et al. 2008. Cytokine IL-1 beta but not IL-1 alpha promoter polymorphism is associated with Alzheimer disease in a population from the Canary Islands, Spain. Eur J Neurol 15: 1080-1084.
11. Du Y, Dodel RC, Eastwood BJ, Bales KR, Gao F, Lohmuller F, et al. 2000. Association of an interleukin 1 alpha polymorphism with Alzheimer's disease. Neurology 55: 480-483.
12. Egger M, Davey SG, Schneider M, Minder C. 1997. Bias in meta-analysis detected by a simple, graphical test. Br Med J 315: 629-634.
13. Fidani L, Goulas A, Mirtsou V, Petersen RC, Tangalos E, Crook R, et al. 2002. Interleukin-1A polymorphism is not associated with late onset Alzheimer's disease. Neurosci Lett 323: 81-83.
14. Giedraitis V, Kilander L, Degerman-Gunnarsson M, Sundelöf J, Axelsson T, Syvänen AC, et al. 2009. Genetic analysis of Alzheimer's disease in the Uppsala Longitudinal Study of Adult Men. Dement Geriatr Cogn Disord 27: 59-68.
15. Green EK, Harris JM, Lemmon H, Lambert JC, Chartier-Harlin MC, St. Clair D, et al. 2002. Are interleukin-1 gene polymorphisms risk factors or disease modifiers in AD? Neurology 58: 1566-1568.
16. Griffin WS, Stanley LC, Ling C, White L, MacLeod V, Perrot LJ, et al. 1989. Brain interleukin 1 and S-100 immunoreactivity are elevated in Down syndrome and Alzheimer disease. Proc Natl Acad Sci U S A 86: 7611-7765.
17. Hayes A, Green EK, Pritchard A, Harris JM, Zhang Y, Lambert JC, et al. 2004. A polymorphic variation in the interleukin1A gene increases brain microglial cell activity in Alzheimer's disease. J Neurol Neurosurg Psychiatry 75: 1475-1477.
18. Hedley R, Hallmayer J, Groth DM, Brooks WS, Gandy SE, Martins RN. 2002. Association of interleukin-1 polymorphisms with Alzheimer's disease in Australia. Ann Neurol 51: 795-797.
19. Hu JL, Li G, Zhou DX, Zou YX, Zhu ZS, Xu RX, et al. 2009. Genetic analysis of interleukin-1A C(-889)T polymorphism with Alzheimer disease. Cell Mol Neurobiol 29: 81-85.
20. Ki CS, Na DL, Kim DK, Kim HJ, Kim JW. 2001. Lack of association of the interleukin-1alpha gene polymorphism with Alzheimer's disease in a Korean population. Ann Neurol 49: 817-818.
21. Kuo YM, Liao PC, Lin C, Wu CW, Huang HM, Lin CC, et al. 2003. Lack of association between interleukin-1alpha polymorphism and Alzheimer disease or vascular dementia. Alzheimer Dis Assoc Disord 17: 94-97.
22. Li XQ, Zhang JW, Zhang ZX, Chen D, Qu QM. 22004. Interleukin-1 gene cluster polymorphisms and risk of Alzheimer's disease in Chinese Han population. J Neural Transm 111: 1183-1190.
23. Mattila KM, Rinne JO, Lehtimaki T, Roytta M, Ahonen JP, Hurme M. 2002. Association of an interleukin 1B gene polymorphism (-511) with Parkinson's disease in Finnish patients. J Med Genet 39: 400-402.
24. McKhann G, Drachman D, Folstein M, Katzman R, Price D, Stadlan EM. 1984. Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDAWork Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease. Neurology 34: 939-944.
25. Minster RL, DeKosky ST, Ganguli M, Belle S, Kamboh MI. 2000. Genetic association studies of interleukin-1 (IL-1A and IL-1B) and interleukin-1 receptor antagonist genes and the risk of Alzheimer's disease. Ann Neurol 48: 817-819.
26. Nicoll JA, Mrak RE, Graham DI, Stewart J, Wilcock, MacGowan S, et al. 2000. Association of interleukin-1 gene polymorphisms with Alzheimer's disease. Ann Neurol 47: 365-368.
27. Nishimura M, Sakamoto T, Kaji R, Kawakami H. 2004. Influence of polymorphisms in the genes for cytokines and glutathione S-transferase omega on sporadic Alzheimer's disease. Neurosci Lett 368: 140-143.
28. Pirskanen M, Hiltunen M, Mannermaa A, Iivonen S, Helisalmi S, Lehtovirta M, et al. 2002. Interleukin 1 alpha gene polymorphism as a susceptibility factor in Alzheimer's disease and its influence on the extent of histopathological hallmark lesions of Alzheimer's disease. Dement Geriatr Cogn Disord 14: 123-127.
29. Prince JA, Feuk L, Sawyer SL, Gottfries J, Ricksten A, Nagga K, et al. 2001. Lack of replication of association findings in complex disease: an analysis of 15 polymorphisms in prior candidate genes for sporadic Alzheimer's disease. Eur J Hum Genet 9: 437-444.
30. Qian Y, Chen W, Wu J, Tao T, Bi L, Xu W, et al. 2010. Association of polymorphism of DNA repair gene XRCC1 with sporadic late-onset Alzheimer's disease and age of onset in elderly Han Chinese. J Neurol Sci 295: 62-65.
31. Qin X, Peng QL, Zeng ZY, Chen ZP, Lin LW, Deng Y, et al. 2012. Interleukin-1A -889C/T polymorphism and risk of Alzheimer's disease: a meta-analysis based on 32 case-control studies. J Neurol DOI 10.1007/s00415-011-6381-6.
32. Rainero I, Bo M, Ferrero M, Valfrè W, Vaula G, Pinessi L. 2004. Association between the interleukin-1α gene and Alzheimer's disease: a meta-analysis. Neurobiol Aging 25: 1293-1298.
33. Ramos EM, Lin MT, Larson EB, Maezawa I, Tseng LH, Edwards KL, et al. 2006. Tumor necrosis factor alpha and interleukin-10 promoter region polymorphisms and risk of late-onset Alzheimer disease. Arch Neurol 63: 1165-1169.
34. Rebeck GW. 2000. Confirmation of the genetic association of interleukin-1A with early onset sporadic Alzheimer's disease. Neurosci Lett 293: 75-77.
35. Ribizzi G, Fiordoro S, Barocci S, Ferrari E, Megna M. 2010. Cytokine polymorphisms and Alzheimer disease: possible associations. Neurol Sci 31: 321-325.
36. Rogers J. 2000. An IL-1-alpha susceptibility polymorphism in Alzheimer's disease: new fuel for the inflammation hypothesis. Neurology 55: 464-465.
37. Rothwell NJ, Luheshi GN. 2000. Interleukin 1 in the brain: biology, pathology and therapeutic target. Trends Neurosci 23: 618-625.
38. Seripa D, Matera MG, Dal Forno G, Gravina C, Masullo C, Daniele A, et al. 2005. Genotypes and haplotypes in the IL-1 gene cluster: analysis of two genetically and diagnostically distinct groups of Alzheimer patients. Neurobiol Aging 26: 455-464.
39. Serretti A, Olgiati P, Politis A, Malitas P, Albani D, Dusi S, et al. 2009. Lack of association between interleukin-1 alpha rs1800587 polymorphism and Alzheimer's disease in two Independent European samples. J Alzheimers Dis 16: 181-187.
40. Sheng JG, Mrak RE, Griffin WS. 1995. Microglial interleukin-1 alpha expression in brain regions in Alzheimer's disease: correlation with neuritic plaque distribution. Neuropathol Appl Neurobiol 21: 290-301.
41. Sheng JG, Mrak RE, Griffin WS. 1997. Glial-neuronal interactions in Alzheimer disease: progressive association of IL-1alpha t microglia and S100beta tastrocytes with neurofibrillary tangle stages. J Neuropathol Exp Neurol 56: 285-290.
42. Sheng JG, Griffin WS, Royston MC, Mrak RE. 1998. Distribution of interleukin-1-immunoreactive microglia in cerebral cortical layers: implications for neuritic plaque formation in Alzheimer's disease. Neuropathol Appl Neurobiol 24: 278-283.
43. Sherrington R, Froelich S, Sorbi S, Campion D, Chi H, Rogaeva EA, et al. 1996. Alzheimer's disease associated with mutations in presenilin 2 is rare and variably penetrant. Hum Mol Genet 5: 985-988.
44. Stewart WF, Kawas C, Corrada M, Metter EJ. 1997. Risk of Alzheimer's disease and duration of NSAID use. Neurology 48: 626-632.
45. Swardfager W, Lanctot K, Rothenburg L, Wong A, Cappell J, Herrmann N. 2010. A metaanalysis of cytokines in Alzheimer's disease. Biol Psychiatry 68: 930-941.
46. Tsai SJ, Liu HC, Liu TY, Wang KY, Hong CJ. 2003. Lack of association between the interleukin-1alpha gene C(-889)T polymorphism and Alzheimer's disease in a Chinese population. Neurosci Lett 343: 93-96.
47. Wang HK, Hsu WC, Fung HC, Lin JC, Hsu HP, Wu YR, et al. 2007. Interleukin-1alpha and -1beta promoter polymorphisms in Taiwanese patients with dementia. Dement Geriatr Cogn Disord 24: 104-110.