Determination of pazopanib (GW-786034) in mouse plasma and brain tissue by liquid chromatography-tandem mass spectrometry (LC/MS-MS)

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 901, Issue , 2012, Pages 85-92

  Minocha, Mukul ^a   Khurana, Varun ^a   Mitra, Ashim K ^a  

^a UNIVERSITY OF MISSOURI KANSAS CITY   (United States)

Author keywords

Brain tissue; GW 786034; LC MS MS; Mouse plasma; Pazopanib; Pharmacokinetics

Indexed keywords

BRAIN TISSUE; GW-786034; LC/MS-MS; MOUSE PLASMA; PAZOPANIB;

ACETONITRILE; BRAIN; FORMIC ACID; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; PHARMACOKINETICS; PLASMAS; POSITIVE IONS;

MAMMALS;

ACETIC ACID ETHYL ESTER; PAZOPANIB; VANDETANIB;

ACCURACY; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN TISSUE; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG BRAIN LEVEL; DRUG DETERMINATION; DRUG ISOLATION; FLOW RATE; LIMIT OF QUANTITATION; LIQUID CHROMATOGRAPHY; MASS SPECTROMETER; MOUSE; NONHUMAN; PRIORITY JOURNAL; SINGLE DRUG DOSE; TANDEM MASS SPECTROMETRY;

ANIMALS; BRAIN CHEMISTRY; CHROMATOGRAPHY, LIQUID; DRUG STABILITY; LEAST-SQUARES ANALYSIS; MICE; PYRIMIDINES; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; SULFONAMIDES; TANDEM MASS SPECTROMETRY;

MUS;

EID: 84863777462     PISSN: 15700232     EISSN: 1873376X     Source Type: Journal    
DOI: 10.1016/j.jchromb.2012.06.004     Document Type: Article

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