Genetic variations and patient-reported quality of life among patients with lung cancer

Journal of Clinical Oncology

Volumn 30, Issue 14, 2012, Pages 1699-1704

  Sloan, Jeff A ^a   De Andrade, Mariza ^a   Decker, Paul ^a   Wampfler, Jason ^a   Oswold, Curtis ^a   Clark, Matthew ^a   Yang, Ping ^a  

^a MAYO CLINIC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLUTATHIONE; METHYLATED DNA PROTEIN CYSTEINE METHYLTRANSFERASE; ABCC4 PROTEIN, HUMAN; DNA METHYLTRANSFERASE; GLUTATHIONE TRANSFERASE; GSTZ1 PROTEIN, HUMAN; MGMT PROTEIN, HUMAN; MULTIDRUG RESISTANCE PROTEIN; MULTIDRUG RESISTANCE PROTEIN 2; MULTIDRUG RESISTANCE-ASSOCIATED PROTEIN 2; POLYDEOXYRIBONUCLEOTIDE SYNTHASE; TUMOR SUPPRESSOR PROTEIN;

ADULT; AGED; ARTICLE; CANCER PATIENT; DNA REPAIR; FATIGUE; FEMALE; GENETIC PREDISPOSITION; GENETIC VARIABILITY; HUMAN; LINEAR ANALOG SELF ASSESSMENT MEASURES; LOGISTIC REGRESSION ANALYSIS; LUNG CANCER SYMPTOM SCALE; LUNG NON SMALL CELL CANCER; MAJOR CLINICAL STUDY; MALE; PAIN; PRIORITY JOURNAL; QUALITY OF LIFE; SINGLE NUCLEOTIDE POLYMORPHISM; CANCER INVASION; CANCER STAGING; COHORT ANALYSIS; COMPARATIVE STUDY; DISEASE FREE SURVIVAL; GENE EXPRESSION REGULATION; GENETICS; LUNG TUMOR; METABOLISM; MIDDLE AGED; MORTALITY; MULTIMODALITY CANCER THERAPY; MULTIVARIATE ANALYSIS; PATHOLOGY; PREDICTIVE VALUE; RETROSPECTIVE STUDY; RISK ASSESSMENT; SELF EVALUATION; SURVIVAL;

ADULT; AGED; AGED, 80 AND OVER; CARCINOMA, NON-SMALL-CELL LUNG; COHORT STUDIES; COMBINED MODALITY THERAPY; DISEASE-FREE SURVIVAL; DNA MODIFICATION METHYLASES; DNA REPAIR ENZYMES; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; GENETIC VARIATION; GLUTATHIONE TRANSFERASE; HUMANS; LUNG NEOPLASMS; MIDDLE AGED; MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS; MULTIVARIATE ANALYSIS; NEOPLASM INVASIVENESS; NEOPLASM STAGING; POLYMORPHISM, SINGLE NUCLEOTIDE; PREDICTIVE VALUE OF TESTS; QUALITY OF LIFE; RETROSPECTIVE STUDIES; RISK ASSESSMENT; SELF-ASSESSMENT; SURVIVAL ANALYSIS; TUMOR SUPPRESSOR PROTEINS;

EID: 84863749231     PISSN: 0732183X     EISSN: 15277755     Source Type: Journal    
DOI: 10.1200/JCO.2010.34.5629     Document Type: Article

References (45)

1. Sherbt GV, Lakshmi MS: The Genetics of Cancer: Genes Associated with Cancer Invasion, Metastasis and Cell Proliferation. Waltham, MA, Academic Press, 1997
2. Sprangers MA, Bartels M, Veenhoven R, et al: Which patient will feel down, which will be happy? The need to study the genetic disposition of emotional states. Qual Life Res 19:1429-1437, 2010
3. Sloan JA, Dueck AC, Erickson PA, et al: Analysis and interpretation of results based on patient-reported outcomes. Value Health 10:S106-S115, 2007 (suppl 2)
4. Hüebner C, Petermann I, Browning BL, et al: Triallelic single nucleotide polymorphisms and geno-typing error in genetic epidemiology studies: MDR1 (ABCB1) G2677/T/A as an example. Cancer Epidemiol Biomarkers Prev 16:1185-1192, 2007
5. Pluzhnikov A, Below JE, Konkashbaev A, et al: Spoiling the whole bunch: Quality control aimed at preserving the integrity of high-throughput geno-typing. Am J Hum Genet 87:123-128, 2010
6. Sebastiani P, Solovieff N, Puca A, et al: Genetic signatures of exceptional longevity in humans. Science [epub ahead of print on July 1, 2010]
7. Fayers PM, Hopwood P, Harvey A, et al: Quality of life assessment in clinical trials: Guidelines and a checklist for protocol writers - The UK Medical Research Council experience: MRC Cancer Trials Office. Eur J Cancer 33:20-28, 1997
8. De Haes J, Curran D, Young T, et al: Quality of life evaluation in oncological clinical trials: The EORTC model. Eur J Cancer 36:821-825, 2000
9. Bottomley A, Jones D, Claassens L: Patient-reported outcomes: Assessment and current perspectives of the guidelines of the Food and Drug Administration and the reflection paper of the European Medicines Agency. Eur J Cancer 45:347-353, 2009
10. Efficace F, Bottomley A, Osoba D, et al: Beyond the development of health-related quality of life (HRQOL) measures: A checklist for evaluating HRQOL outcomes in cancer clinical trials - Does HRQOL evaluation in prostate cancer research inform clinical decision making? J Clin Oncol 21:3502-3511, 2003
11. Bogardus ST Jr, Concato J, Feinstein AR: Clinical epidemiological quality in molecular genetic research: The need for methodological standards. JAMA 281:1919-1926, 1999
12. Pelias MZ: Federal regulations and the future of research in human and medical genetics. J Contin Educ Health Prof 21:238-246, 2001
13. Sloan JA, McLeod H, Sargent D, et al: Preliminary evidence of relationship between genetic markers and oncology patient quality of life (QOL). J Clin Oncol 22, 2004 (suppl; abstr 5)
14. Hampton T: Patients' genes may influence quality of life before cancer chemotherapy. JAMA 292:673-674, 2004
15. Goldberg RM, Sargent DJ, Morton RF, et al: A randomized controlled trial of fluorouracil plus leucovorin, irinotecan, and oxaliplatin combinations in patients with previously untreated metastatic colorectal cancer. J Clin Oncol 22:23-30, 2004
16. Sloan JA, Zhao CX: Genetics and quality of life. Curr Probl Cancer 30:255-260, 2006
17. Sprangers MA, Sloan JA, Veenhoven R, et al: The establishment of the GENEQOL consortium to investigate the genetic disposition of patient-reported quality-of-life outcomes. Twin Res Hum Genet 12:301-311, 2009
18. Shi Q, Cleeland CS, Klepstad P, et al: Biological pathways and genetic variables involved in pain. Qual Life Res 19:1407-1417, 2010
19. Barsevick A, Frost M, Zwinderman A, et al: I'm so tired: Biological and genetic mechanisms of cancer-related fatigue. Qual Life Res 19:1419-1427, 2010
20. Chauhan C: Optimists doing something different: A patient's view of geneQOL research. Qual Life Res 19:1405-1406, 2010
21. Sprangers MA, Sloan JA, Barsevick A, et al: Scientific imperatives, clinical implications, and theoretical underpinnings for the investigation of the relationship between genetic variables and patient-reported quality-of-life outcomes. Qual Life Res 19: 1395-1403, 2010
22. Sugimura H, Yang P: Long-term survivorship in lung cancer: A review. Chest 129:1088-1097, 2006
23. Rausch SM, Clark MM, Patten C, et al: Relationship between cytokine gene single nucleotide polymorphisms and symptom burden and quality of life in lung cancer survivors. Cancer 116:4103-4113, 2010
24. Clark MM, Novotny PJ, Patten CA, et al: Motivational readiness for physical activity and quality of life in long-term lung cancer survivors. Lung Cancer 61:117-122, 2008
25. Yang P, Allen MS, Aubry MC: Clinical features of 5,628 primary lung cancer patients: Experience at Mayo Clinic from 1997 to 2003. Chest 128:452-462, 2005
26. Svobodník A, Yang P, Novotny PJ, et al: Quality of life in 650 lung cancer survivors 6 months to 4 years after diagnosis. Mayo Clin Proc 79:1024-1030, 2004
27. Hollen PJ, Gralla RJ, Kris MG, et al: Quality of life assessment in individuals with lung cancer: Testing the Lung Cancer Symptom Scale (LCSS). Eur J Cancer 29A:S51-S58, 1993 (suppl 1)
28. Hollen PJ, Gralla RJ, Kris MG, et al: Normative data and trends in quality of life from the Lung Cancer Symptom Scale (LCSS). Support Care Cancer 7:140-148, 1999
29. Locke DE, Decker PA, Sloan JA, et al: Validation of single-item linear analog scale assessment of quality of life in neuro-oncology patients. J Pain Symptom Manage 34:628-638, 2007
30. Butt Z, Wagner LI, Beaumont JL, et al: Use of a single-item screening tool to detect clinically significant fatigue, pain, distress, and anorexia in ambulatory cancer practice. J Pain Symptom Manage 35:20-30, 2008
31. Sloan JA, Berk L, Roscoe J, et al: Integrating patient-reported outcomes into cancer symptom management clinical trials supported by the National Cancer Institute-sponsored clinical trials network. J Clin Oncol 25:5070-5077, 2007
32. Buchanan DR, O'Mara A, Kelaghan JW, et al: Challenges and recommendations for advancing the state-of-the-science of quality-of-life assessment in symptom management trials. Cancer 110:1621-1628, 2007
33. Sun Z, Chen J, Aakre J, et al: Genetic variation in glutathione metabolism and DNA repair genes predicts survival of small-cell lung cancer patients. Ann Oncol 21:2011-2016, 2010
34. Pankratz VS, Sun Z, Aakre J, et al: Systematic evaluation of genetic variants in three biological pathways on patient survival in low-stage non-small cell lung cancer. J Thorac Oncol 6:1488-1495, 2011
35. Li Y, Sun Z, Cunningham JM, et al: Genetic variations in multiple drug action pathways and survival in advanced-stage non-small cell lung cancer treated with chemotherapy. Clin Cancer Res 17:3830-3840, 2011
36. Krześniak M, Butkiewicz D, Samojedny A, et al: Polymorphisms in TDG and MGMT genes: Epidemiological and functional study in lung cancer patients from Poland. Ann Hum Genet 68:300-312, 2004
37. Colombo S, Soranzo N, Rotger M, et al: Influence of ABCB1, ABCC1, ABCC2, and ABCG2 haplotypes on the cellular exposure of nelfinavir in vivo. Pharmacogenet Genomics 15:599-608, 2005
38. Niemi M:. Transporter pharmacogenetics and statin toxicity. Clin Pharmacol Ther 87:130-133, 2010
39. Blackburn AC, Woollatt E, Sutherland GR, et al: Characterization and chromosome location of the gene GSTZ1 encoding the human zeta class glutathione transferase and maleylacetoacetate isomerase. Cytogenet Cell Genet 83:109-114, 1998
40. Fang YY, Kashkarov U, Anders MW, et al: Polymorphisms in the human glutathione transferase zeta promoter. Pharmacogenet Genomics 16:307-313, 2006
41. Recht A, Edge SB, Solin LJ, et al: Postmastectomy radiotherapy: Clinical practice guidelines of the American Society of Clinical Oncology. J Clin Oncol 19:1539-1569, 2001
42. Rummans TA, Clark MM, Sloan JA, et al: Impacting quality of life for patients with advanced cancer with a structured multidisciplinary intervention: A randomized controlled trial. J Clin Oncol 24:635-642, 2006
43. Gotay CC, Kawamoto CT, Bottomley A, et al: The prognostic significance of patient-reported outcomes in cancer clinical trials. J Clin Oncol 26:1355-1363, 2008
44. Montezari A: Quality of life data as prognostic indicators of survival in cancer patients: An overview of the literature from 1982 to 2008. Health Qual Life Outcomes 7:102, 2009
45. Hahn EA, Cella D, Chassany O, et al: Precision of health-related quality-of-life data compared with other clinical measures. Mayo Clin Proc 82:1244-1254, 2007