Therapeutic properties of quercetin on monosodium urate crystal-induced inflammation in rat

Journal of Pharmacy and Pharmacology

Volumn 64, Issue 8, 2012, Pages 1119-1127

  Huang, Jingqun ^a   Zhu, Miaozhang ^a   Tao, Ye ^c   Wang, Siwang ^a   Chen, Jianzong ^b   Sun, Wenjuan ^a   Li, Shuye ^a  

^a FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^b FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^c TIANJIN UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

Author keywords

Antioxidant enzymes; Cytokines; Gouty arthritis; Lipid peroxidation; Quercetin

Indexed keywords

CATALASE; CHEMOKINE; GLUTATHIONE PEROXIDASE; INDOMETACIN; MALONALDEHYDE; Q 4951 100G; QUERCETIN; SUPEROXIDE DISMUTASE; UNCLASSIFIED DRUG; URATE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANKLE EDEMA; ARTICLE; BLOOD LEVEL; CATALASE BLOOD LEVEL; CHEMOKINE BLOOD LEVEL; CONTROLLED STUDY; CRYSTAL; DOSE RESPONSE; ENZYME ACTIVITY; ENZYME BLOOD LEVEL; GLUTATHIONE PEROXIDASE BLOOD LEVEL; GOUT; HINDLIMB; HISTOPATHOLOGY; LEUKOCYTE MIGRATION; LIPID PEROXIDATION; LIVER; MALE; NONHUMAN; PROTEIN BLOOD LEVEL; RAT; SUPEROXIDE DISMUTASE BLOOD LEVEL; SYNOVIUM; TISSUE SECTION; TREATMENT RESPONSE;

ANIMALS; ANKLE JOINT; ANTI-INFLAMMATORY AGENTS; ANTIOXIDANTS; ARTHRITIS, GOUTY; CHEMOKINES; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; EDEMA; GOUT SUPPRESSANTS; INFLAMMATION; LIPID PEROXIDATION; LIVER; MALE; MALONDIALDEHYDE; NEUTROPHIL INFILTRATION; PHYTOTHERAPY; PLANT EXTRACTS; QUERCETIN; RATS; RATS, SPRAGUE-DAWLEY; SYNOVIAL MEMBRANE; URIC ACID;

EID: 84863724275     PISSN: 00223573     EISSN: 20427158     Source Type: Journal    
DOI: 10.1111/j.2042-7158.2012.01504.x     Document Type: Article

References (31)

1. Gentle MJ,. Sodium urate arthritis: effects on the sensory properties of articular afferents in the chicken. Pain 1997; 70: 245-251. (Pubitemid 27188580)
2. Guerne PA, et al,. Inflammatory microcrystals stimulate interleukin-6 production and secretion by human monocytes and synoviocytes. Arthritis Rheum 1989; 32: 1443-1452.
3. Di Giovine FS, et al,. Urate crystals stimulate production of tumour necrosis factor alpha from human blood monocytes and synovial cells: cytokine mRNA and protein kinetics, and cellular distribution. J Clin Invest 1991; 87: 175-181.
4. Martin WJ, et al,. Sesquiterpene dialdehydes inhibit MSU crystal-induced superoxide production by infiltrating neutrophils in an in vivo model of gouty inflammation. Free Radic Biol Med 2009; 47: 616-621.
5. Manach C, et al,. Bioavailability and bioefficacy of polyphenols in humans: I. Review of 97 bioavailability studies. Am J Clin Nutr 2005; 81: 230S-242S.
6. Khanna D, et al,. Natural products as a gold mine for arthritis treatment. Curr Opin Pharmacol 2007; 7: 344-351. (Pubitemid 46731200)
7. Kawabata K, et al,. Suppressive effect of quercetin on acute stress-induced hypothalamic-pituitary-adrenal axis response in Wistar rats. J Nutr Biochem 2010; 21: 374-380.
8. Mamani-Matsuda M, et al,. Therapeutic and preventive properties of quercetin in experimental arthritis correlate with decreased macrophage inflammatory mediators. Biochem Pharmacol 2006; 72: 1304-1310. (Pubitemid 44604286)
9. Shrestha M, et al,. Randomized double-blind comparison of the analgesic efficacy of intramuscular ketorolac and oral indomethacin in the treatment of acute gouty arthritis. Ann Emerg Med 1995; 26: 682-686.
10. Sabina EP, Rasool M,. An in vivo and in vitro potential of Indian ayurvedic herbal formulation Triphala on experimental gouty arthritis in mice. Vascul Pharmacol 2008; 48: 14-20.
11. Sabina EP, et al,. 6-Shogaol inhibits monosodium urate crystal-induced inflammation-An in vivo and in vitro study. Food Chem Toxicol 2010; 48: 229-235.
12. Miguélez R, et al,. Anti-inflammatory effect of a PAF receptor antagonist and a new molecule with antiproteinase activity in an experimental model of acute urate crystal arthritis. J Lipid Mediat Cell Signal 1996; 13: 35-49. (Pubitemid 26032172)
13. Shireen KF, et al,. Effects of dietary vitamin E, C and soybean oil supplementation on antioxidant enzyme activities in liver and muscles of rats. Food Chem Toxicol 2008; 46: 3290-3294.
14. Giacomelli R, et al,. Combination therapy with cyclosporine and methotrexate in patients with early rheumatoid arthritis soon inhibits TNFalpha production without decreasing TNFalpha mRNA levels. An in vivo and in vitro study. Clin Exp Rheumatol 2002; 20: 365-372. (Pubitemid 35012571)
15. Inokuchi T, et al,. Plasma interleukin (IL)-18 (interferon-g-inducing factor) and other inflammatory cytokines in patients with gouty arthritis and monosodium urate monohydrate crystal-induced secretion of IL-18. Cytokine 2006; 33: 21-27. (Pubitemid 43220348)
16. Arend WP, et al,. The biological role of naturally-occurring cytokine inhibitors. Br J Rheumatol 1991; 30: 49-52.
17. Yelin E, Wanke LA,. An assessment of the annual and long-term direct costs of rheumatoid arthritis: the impact of poor function and functional decline. Arthritis Rheum 1999; 42: 1209-1218. (Pubitemid 29268958)
18. Mythilypriya R, et al,. Ameliorating effect of Kalpaamruthaa, a Siddha preparation in adjuvant induced arthritis in rats with reference to changes in proinflammatory cytokines and acute phase proteins. Chem Biol Interact 2009; 179: 335-343.
19. Kim MJ, et al,. Methanol extract of Dioscoreae Rhizoma inhibits pro-inflammatory cytokines and mediators in the synoviocytes of rheumatoid arthritis. Int Immunopharmacol 2004; 4: 1489-1497.
20. Rai MF, et al,. Quantification of cytokines and inflammatory mediators in a three-dimensional model of inflammatory arthritis. Cytokine 2008; 42: 8-17.
21. Lee HS, et al,. Inhibition of cyclooxygenase 2 expression by diallyl sulfide on joint inflammation induced by urate crystal and IL-1beta. Osteoarthritis Cartilage 2009; 17: 91-99.
22. Chen L, et al,. Stimulation of inducible nitric oxide synthase by monosodium urate crystals in macrophages and expression of iNOS in gouty arthritis. Nitric Oxide 2004; 11: 228-236. (Pubitemid 39582753)
23. Farrell AJ, et al,. Increased concentrations of nitrite in synovial fluid and serum samples suggest increased nitric oxide synthesis in rheumatic diseases. Ann Rheum Dis 1992; 51: 1219-1222.
24. Miyasaka N, Hirata Y,. Nitric oxide and inflammatory arthritides. Life Sci 1997; 61: 2073-2081. (Pubitemid 27478834)
25. Ueki Y, et al,. Increased nitric oxide levels in patients with rheumatoid arthritis. J Rheumatol 1996; 23: 230-236. (Pubitemid 26078379)
26. Rasool M, Varalakshmi P,. Suppressive effect of Withania somnifera root powder on experimental gouty arthritis: an in vivo and in vitro study. Chem Biol Interact 2006; 164: 174-180. (Pubitemid 44779571)
27. Segal AW,. How neutrophils kill microbes. Annu Rev Immunol 2005; 23: 197-223. (Pubitemid 40563169)
28. Afonso V, et al,. Reactive oxygen species and superoxide dismutases: role in joint diseases. Joint Bone Spine 2007; 74: 324-329. (Pubitemid 47049827)
29. Salvi M, et al,. Catalase takes part in rat liver mitochondria oxidative stress defense. J Biol Chem 2007; 282: 24407-24415. (Pubitemid 47328021)
30. Sarban S, et al,. Plasma total antioxidant capacity, lipid peroxidation, and erythrocyte antioxidant enzyme activities in patients with rheumatoid arthritis and osteoarthritis. Clin Biochem 2005; 38: 981-986. (Pubitemid 41606795)
31. Messarah M, et al,. Influence of thyroid dysfunction on liver lipid peroxidation and antioxidant status in experimental rats. Exp Toxicol Pathol 2010; 62: 301-310.