Immunohistochemical analysis on cyclooxygenase-2 for wound age determination

International Journal of Legal Medicine

Volumn 126, Issue 3, 2012, Pages 435-440

  Ishida, Yuko ^a   Kimura, Akihiko ^a   Nosaka, Mizuho ^a   Kuninaka, Yumi ^a   Takayasu, Tatsunori ^b   Eisenmenger, Wolfgang ^c   Kondo, Toshikazu ^a  

^a WAKAYAMA MEDICAL UNIVERSITY   (Japan)

^b KANAZAWA UNIVERSITY   (Japan)

^c UNIVERSITY OF MUNICH   (Germany)

Author keywords

Cyclooxygenase 2; Forensic pathology; Immunohistochemistry; Wound age determination

Indexed keywords

CD68 ANTIGEN, HUMAN; CYCLOOXYGENASE 2; DIFFERENTIATION ANTIGEN; LEUKOCYTE ANTIGEN; PEROXIDASE;

ARTICLE; FORENSIC PATHOLOGY; HUMAN; IMMUNOHISTOCHEMISTRY; IMMUNOLOGY; INJURY; MACROPHAGE; METABOLISM; NEUTROPHIL; PHYSIOLOGY; SKIN; TIME; WOUND HEALING;

ANTIGENS, CD; ANTIGENS, DIFFERENTIATION, MYELOMONOCYTIC; CYCLOOXYGENASE 2; FORENSIC PATHOLOGY; HUMANS; IMMUNOHISTOCHEMISTRY; MACROPHAGES; NEUTROPHILS; PEROXIDASE; SKIN; TIME FACTORS; WOUND HEALING;

EID: 84863723476     PISSN: 09379827     EISSN: 14371596     Source Type: Journal    
DOI: 10.1007/s00414-012-0685-7     Document Type: Article

References (45)

1. Kondo T (2007) Timing of skin wounds. Leg Med (Tokyo) 9:109- 114.
2. Kondo T, Ishida Y (2010) Molecular pathology of wound healing. Forensic Sci Int 203:93-98.
3. Cecchi R (2010) Estimating wound age: looking into the future. Int J Legal Med 124:523-536.
4. Betz P (1994) Histological and enzyme histochemical parameters for the age estimation of human skin wounds. Int J Legal Med 107:60-68.
5. An JL, Ishida Y, Kimura A, Kondo T (2011) Immunohistochemical examination of intracerebral aquaporin-4 expression and its application for differential diagnosis between freshwater and saltwater drowning. Int J Legal Med 125:59-65.
6. An JL, Ishida Y, Kimura A, Kondo T (2010) Forensic application of intrarenal aquaporin-2 expression for differential diagnosis between freshwater and saltwater drowning. Int J Legal Med 124:99- 104.
7. Nosaka M, Ishida Y, Kimura A, Kondo T (2010) Immunohistochemical detection of MMP-2 and MMP-9 in a stasis-induced deep vein thrombosis model and its application to thrombus age estimation. Int J Legal Med 124:439-444.
8. Nosaka M, Ishida Y, Kimura A, Kondo T (2009) Time-dependent appearance of intrathrombus neutrophils and macrophages in a stasis-induced deep vein thrombosis model and its application to thrombus age determination. Int J Legal Med 123:235-240.
9. Fracasso T, Pfeiffer H, Michaud K, Köhler H, Sauerland C, Schmeling A (2011) Immunohistochemical expression of fibronectin and C5b-9 in the myocardium in cases of carbon monoxide poisoning. Int J Legal Med 125:377-384.
10. Yoshida C, Ishikawa T, Michiue T, Quan L, Maeda H (2011) Postmortem biochemistry and immunohistochemistry of chromogranin A as a stress marker with special regard to fatal hypothermia and hyperthermia. Int J Legal Med 125:11-20.
11. Bohnert M, Anderson J, Rothschild MA, Böhm J (2010) Immunohistochemical expression of fibronectin in the lungs of fire victims proves intravital reaction in fatal burns. Int J Legal Med 124:583-588.
12. Dressler J, Hanisch U, Kuhlisch E, Geiger KD (2007) Neuronal and glial apoptosis in human traumatic brain injury. Int J Legal Med 121:365-375.
13. Kondo T, Tanaka J, Ishida Y, Mori R, Takayasu T, Ohshima T (2002) Ubiquitin expression in skin wounds and its application to forensic wound age determination. Int J Legal Med 116:267-272.
14. Ishida Y, Kimura A, Takayasu T, Eisenmenger W, Kondo T (2008) Expression of oxygen-regulated protein 150 (ORP150) in skin wound healing and its application for wound age determination. Int J Legal Med 122:409-414.
15. Ishida Y, Kimura A, Takayasu T, Eisenmenger W, Kondo T (2009) Detection of fibrocytes in human skin wounds and its application for wound age determination. Int J Legal Med 123:299- 304.
16. Kondo T, Ohshima T, Eisenmenger W(1999) Immunohistochemical and morphometrical study on the temporal expression of interleukin- 1α (IL-1α) in human skin wounds for forensic wound age determination. Int J Legal Med 112:249-252.
17. Hayashi T, Ishida Y, Kimura A, Takayasu T, Eisenmenger W, Kondo T (2004) Forensic application of VEGF expression to skin wound age determination. Int J Legal Med 118:320-325.
18. Kondo T, Ohshima T, Mori R, Guan DW, Ohshima K, Eisenmenger W (2002) Immunohistochemical detection of chemokines in human skin wounds and its application to wound age determination. Int J Legal Med 116:87-91.
19. Ma WX, Yu TS, Fan YY, Zhang ST, Ren P, Wang SB, Zhao R, Pi JB, Guan DW (2011) Time-dependent expression and distribution of monoacylglycerol lipase during the skin-incised wound healing in mice. Int J Legal Med 125:549-558.
20. Yu TS, Cheng ZH, Li LQ, Zhao R, Fan YY, Du Y, Ma WX, Guan DW (2010) The cannabinoid receptor type 2 is time-dependently expressed during skeletal muscle wound healing in rats. Int J Legal Med 124:397-404.
21. Betz P (1995) Immunohistochemical parameters for the age estimation of human skin wounds. A review. Am J Forensic Med Pathol 16:203-209.
22. Martin P (1997) Wound healing-aiming for perfect skin regeneration. Science 276:75-81.
23. Singer AJ, Clark RA (1999) Cutaneous wound healing. N Engl J Med 341:738-746.
24. Gillitzer R, Goebeler M (2001) Chemokines in cutaneous wound healing. J Leukoc Biol 69:513-521.
25. Martin P, Leibovich SJ (2005) Inflammatory cells during wound repair: the good, the bad and the ugly. Trends Cell Biol 15:599- 607.
26. Ishida Y, Gao JL, Murphy PM (2008) Chemokine receptor CX3CR1 mediates skin wound healing by promoting macrophage and fibroblast accumulation and function. J Immunol 180:569-579.
27. Ishida Y, Kondo T, Kimura A, Matsushima K, Mukaida N (2006) Absence of IL-1 receptor antagonist impaired wound healing along with aberrant NF-κB activation and a reciprocal suppression of TGF-β signal pathway. J Immunol 176:5598-5606.
28. Ishida Y, Kondo T, Takayasu T, Iwakura Y, Mukaida N (2004) The essential involvement of cross-talk between IFN-γ and TGF-β in the skin wound-healing process. J Immunol 172:1848-1855.
29. Lin ZQ, Kondo T, Ishida Y, Takayasu T, Mukaida N (2003) Essential involvement of IL-6 in the skin wound-healing process as evidenced by delayed wound healing in IL-6-deficient mice. J Leukoc Biol 73:713-721.
30. Mori R, Kondo T, Ohshima T, Ishida Y, Mukaida N (2002) Accelerated wound healing in tumor necrosis factor receptor p55- deficient mice with reduced leukocyte infiltration. FASEB J 16:963-974.
31. Laulederkind SJ, Thompson-Jaeger S, Goorha S, Chen Q, Fu A, Rho JY, Ballou LR, Raghow R (2002) Both constitutive and inducible prostaglandin H synthase affect dermal wound healing in mice. Lab Invest 82:919-927.
32. Dubois RN, Abramson SB, Crofford L, Gupta RA, Simon LS, Van De Putte LB, Lipsky PE (1998) Cyclooxygenase in biology and disease. FASEB J 12:1063-1073.
33. Warner TD, Mitchell JA (2004) Cyclooxygenases: new forms, new inhibitors, and lessons from the clinic. FASEB J 18:790-804.
34. Foitzik T, Hotz HG, Hotz B, Wittig F, Buhr HJ (2003) Selective inhibition of cyclooxygenase-2 (COX-2) reduces prostaglandin E2 production and attenuates systemic disease sequelae in experimental pancreatitis. Hepatogastroenterology 50:1159-1162.
35. Hayashi T, Ishida Y, Kimura A, Iwakura Y, Mukaida N, Kondo T (2007) IFN-γ protects cerulein-induced acute pancreatitis by repressing NF-κB activation. J Immunol 178:7385-7394.
36. King SJ, Werrett DJ, Harrison DT (1989) The evaluation of an ELISA for semen-specific 19-OH prostaglandin F1 alpha/F2 alpha using ex-casework swabs and stains. Forensic Sci Int 42:103-123.
37. King SJ, Kelly RW, Sutton JG (1989) The development of an enzyme-linked immunosorbent assay for 19-OH PG F1 alpha/F2 alpha. Forensic Sci Int 40:211-216.
38. King SJ, Sutton JG, Trewsdale LA (1989) Radioimmunoassay detection limits for 19-OH F1 alpha/F2 alpha prostaglandin in normal, infertile and vasectomized semen stains. Analysis of saliva, sweat and urine for possible non-specific or matrix effects. Forensic Sci Int 40:221-229.
39. King SJ, Sutton JG (1989) A survey of the concentration of 19-OH F1 alpha/F2 alpha prostaglandins in the semen of fertile, infertile and vasectomized men and their stability in both liquid semen and semen stains. Forensic Sci Int 40:217-220.
40. Sutton JG, King SJ, Taylor M (1987) The application of a simple RIA technique for the detection of 19-OH F1 alpha/F2 alpha prostaglandin, a specific semen marker, in semen contaminated vaginal swabs: time since intercourse studies. Forensic Sci Int 34:143-153.
41. Sutton JG, Kelly RW, Morris BA (1987) Evaluation of the 190H analogues of prostaglandins E1, E2, F1 alpha and F2 alpha as specific markers for the identification of human semen in body fluid mixtures. Forensic Sci Int 33:103-116.
42. He L, Zhu J (1996) Distinguishing antemortem from postmortem injuries by LTB4 quantification. Forensic Sci Int 31:11-16.
43. Hernández-Cueto C, Vieira DN, Girela E, Marques E, Calvo MD, Villalobos M, Oliveira de Sà F, Villanueva E (1994) Prostaglandin F2a (PGF2a): an inadequate marker of the vitality of wounds? Int J Legal Med 106:312-314.
44. Bai R, Wan L, Shi M (2008) The time-dependent expressions of IL- 1beta, COX-2, MCP-1 mRNA in skin wounds of rabbits. Forensic Sci Int 175:193-197.
45. Kondo T, Ohshima T (1996) The dynamics of inflammatory cytokines in the healing process of mouse skin wound: a preliminary study for possible wound age determination. Int J Legal Med 108:231-236.