Immunohistochemical and morphometrical study on the temporal expression of interleukin-1α (IL-1α) in human skin wounds for forensic wound age determination

International Journal of Legal Medicine

Volumn 112, Issue 4, 1999, Pages 249-252

  Kondo, T ^a   Ohshima, T ^a   Eisenmenger, W ^b  

^a KANAZAWA UNIV SCHOOL OF MEDICINE   (Japan)

^b UNIVERSITY OF MUNICH   (Germany)

Author keywords

Forensic pathology; Immunohistochemistry; Interleukin 1 (IL 1 ); Morphometrical analysis; Wound age determination

Indexed keywords

INTERLEUKIN 1ALPHA;

ADOLESCENT; ADULT; AGED; ARTICLE; CELL INFILTRATION; CHILD; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; FEMALE; FORENSIC PATHOLOGY; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MALE; MORPHOMETRICS; NEUTROPHIL; POLYMORPHONUCLEAR CELL; PRIORITY JOURNAL; WOUND;

ADOLESCENT; ADULT; AGED; CHILD; FEMALE; GENE EXPRESSION; HUMANS; IMMUNOENZYME TECHNIQUES; INTERLEUKIN-1; MALE; MIDDLE AGED; POSTMORTEM CHANGES; SKIN; TIME FACTORS; WOUNDS AND INJURIES;

EID: 0033022660     PISSN: 09379827     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004140050244     Document Type: Article

References (28)

1. Raekallio J (1972) Determination of the age of wounds by histochemical and biochemical methods. Forensic Sci Int 1:3-16
2. Laiho K (1998) Myeloperoxidase activity in skin lesions. I. Influence of the loss of blood, depth of excoriations and thickness of the skin. Int J Legal Med 111:6-9
3. Laiho K (1998) Myeloperoxidase activity in skin lesions. II. Influence of alcohol and some medicines. Int J Legal Med 111: 10-12
4. Eisenmenger W, Nerlich A, Glück G (1988) Die Bedeutung des Kollagens bei Wundaltersbestimmung. Z Rechtsmed 100: 79-100
5. Oehmichen M (1990) Die Wundheilung. Springer, Berlin Heidelberg New York, pp 5-67
6. Oehmichen M, Cröpelin A (1995) Temporal course of intravital and postmortem proliferation of epidermal cells after injury - an immunohistochemical study using bromodeoxyuridine in rats. Int J Legal Med 107:257-262
7. Betz P (1994) Histological and enzyme histochemical parameters for the age estimation of human skin wounds. Int J Legal Med 107:60-68
8. Betz P, Nerlich A, Wilske J, Tübel J, Penning R, Eisenmenger W (1993) The time-dependent localization of Ki-67 antigen-positive cells in human skin wounds. Int J Legal Med 106:35-40
9. Betz P, Nerlich A, Wilske J, Tübel J, Wiest I, Penning R, Eisenmenger W (1992) Immunohistochemical localization of fibronectin as a tool for the age determination of human skin wounds. Int J Legal Med 105:21-26
10. Betz P, Nerlich A, Wilske J, Tübel J, Wiest I, Penning R, Eisenmenger W (1992) The time-dependent rearrangement of epithelial basement membrane in human skin wounds - immunohistochemical localization of collagen IV and VII. Int J Legal Med 105:93-97
11. Betz P, Nerlich A, Wilske J, Tübel J, Penning R, Eisenmenger W (1993) Analysis of the immunohistochemical localization of collagen type III and V for the time-estimation of human skin wounds. Int J Legal Med 105:329-332
12. Betz P, Nerlich A, Wilske J, Tübel J, Penning R, Eisenmenger W (1993) Immunohistochemical localization collagen types I and VI in human skin wounds. Int J Legal Med 106:31-34
13. Dreßler J, Bachmann L, Kasper M, Hauck JG, Müller E (1997) Time dependence of the expression of ICAM (CD-54) in human skin wounds. Int J Legal Med 110:299-304
14. Betz P, Nerlich A, Tilbel J, Wiest I, Hausmann R (1997) Detection of cell death in human skin wounds of various ages by an in situ end labeling of nuclear DNA fragments. Int J Legal Med 110:240-243
15. Betz P, Eisenmenger W (1996) Morphometrical analysis of hemosiderin deposits in relation to wound age. Int J Legal Med 108:262-264
16. Hausmann R, Nerlich A, Betz P (1998) The time-related expression of p53 protein in human skin wounds - a quantitative immunohistochemical analysis. Int J Legal Med 111:169-172
17. Kondo T, Ohshima T (1996) The dynamics of inflammatory cytokines in the healing process mouse skin wound: a preliminary study for possible wound age determination. Int J Legal Med 108:231-236
18. Kondo T, Ohshima T (1996) Experimental study on the estimation of skin wound age after injury by immunostaining interleukin 1α, collagen type I and fibronectin. In: Oehmichen M, Kirchner H (eds) Rechtsmedizinische Forschungsergebnisse, Band 13, The wound healing process - Forensic pathological aspects. Schmidt-Römhild, Lübeck, pp 123-132
19. Oppenheim JJ, Kovacs EJ, Matsushima K, Durum SK (1986) There is more than one interleukin-1. Immunol Today 7:45-56
20. Auron PE, Webb AC, Rosenwasser LJ, Mucci SF, Rich A. Wolff SM, Dinarello CA (1984) Nucleotide sequence of human monocyte interleukin 1 precursor cDNA. Proc Natl Acad Sci USA 81:7907-7911
21. Lomedico PT, Gubler U, Hellmann CP, Dukovich M, Giri JG, Pan YCE, Collier K, Semionow R, Chua AO, Mizel SB (1984) Cloning and expression of murine interleukin-1 cDNA in Escherichia coli. Nature 312:458-462
22. Dinarello CA (1994) Interleukin-1. In: Thomson A (ed) The cytokine handbook, 2nd edn. Academic Press, London, pp 31-56
23. Baumann H, Gauldie J (1994) The acute phase response. Immunol Today 15:74-80
24. Anttila HSI, Reitamo S, Erkko P, Miettinen A, Didierjean L, Saurat JH (1990) Membrane and cytosolic interleukin-1 alpha and beta in normal human epidermal cells: variability of epitope exposure in immunohistochemistry. J Invest Dermatol 93: 31-38
25. Reitamo S, Anttila HSI, Didierjean L, Saurat JH (1990) Immunohistochemical identification of interleukin 1α and β in human eccrine sweat-gland apparatus. Br J Dermatol 122:315-323
26. Ohshima T, Sato Y (1998) Time-dependent expression of interleukin-10 (IL-10) mRNA during the early phase of skin wound healing as possible indicator of wound vitality. Int J Legal Med 111:251-255
27. Sato Y, Kondo T, Minamino T, Ohshima T (1997) Gene expression of inflammatory cytokines during mouse skin wound healing. Inflamm Res 46:s220
28. Ford HR, Hoffman RA, Wing EJ, Magee DM, McIntyre L, Simmons R (1989) Characterization of wound cytokines in the sponge matrix model. Arch Surg 124:1422-1428