Pathogenesis of migraine: Role of neuromodulators

Headache

Volumn 52, Issue 7, 2012, Pages 1155-1163

  D'Andrea, Giovanni ^a   D'Arrigo, Antonello ^a   Dalle Carbonare, Maurizio ^a   Leon, Alberta ^a  

^a Research and Innovation SpA   (Italy)

Author keywords

elusive amines; migraine; pathogenesis

Indexed keywords

4 AMINOBUTYRIC ACID; AMINE; CALCITONIN GENE RELATED PEPTIDE; CATECHOLAMINE; DOPAMINE; EXCITATORY AMINO ACID; NORADRENALIN; OCTOPAMINE; OXEDRINE; TRYPTOPHAN; TYRAMINE; TYROSINE;

CENTRAL NERVOUS SYSTEM; DOPAMINERGIC SYSTEM; HUMAN; MIGRAINE; NEUROMODULATION; NONHUMAN; NORADRENERGIC SYSTEM; PATHOGENESIS; PRIORITY JOURNAL; REVIEW; SYNAPSE;

DOPAMINE; HUMANS; MIGRAINE DISORDERS; NEUROTRANSMITTER AGENTS; NOREPINEPHRINE; TYROSINE;

EID: 84863723148     PISSN: 00178748     EISSN: 15264610     Source Type: Journal    
DOI: 10.1111/j.1526-4610.2012.02168.x     Document Type: Review

References (62)

1. Launer LJ, Terwindt GM, Ferrari MD,. The prevalence and characteristics of migraine in a population based cohort: The GEM study. Neurology. 1999; 53: 537-542.
2. Welch KMA,. Migraine a biobehavioral disorder. Arch Neurol. 1987; 44: 323-327.
3. Welch KMA, D'Andrea G, Tepley N, Barkley G, Ramadan NM,. The concept of migraine as a state of central neuronal hyperexcitability. Neurol Clin. 1990; 8: 817-828.
4. Migraine P,. Migraine: A genetic disease? Neurol Sci. 2008; 29: S47-S51.
5. Ziegler DK, Paolo AM,. Headache symptoms and psychological profile of headache-prone individuals: A comparison of clinic patients and controls. Arch Neurol. 1995; 52: 602-606.
6. D'Andrea G, Perini F, Terrazzino S, Nordera GP,. Contributions of biochemistry to the pathogenesis of primary headaches. Neurol Sci. 2004; 3 (Suppl 3): 589-592.
7. Millan MJ,. Descending control of pain. Prog Neurobiol. 2002; 66: 355-474.
8. D'Andrea G, Nordera GP, Perini F, Allais G, Granella F,. Biochemistry of neuromodulation in primary headaches: Focus on tyrosine metabolism. Neurol Sci. 2007; 28: S94-S96.
9. D'Andrea G, Terrazzino S, Fortin D, Cocco P, Balbi T,. Elusive amines and primary Headaches: Historical background and prospectives. Neurol Sci. 2003; 24: S65-S67.
10. Axelrod J, Saavedra JM,. Octopamine. Nature. 1977; 265: 501-504.
11. Sever PS,. False transmitters and migraine. Lancet. 1979; 1: 333.
12. Borowsky B, Adham N, Jones KA, et al,. Trace amines: Identification of a family of mammalian G protein-coupled receptors. Proc Natl Acad Sci U S A. 2001; 98: 933-941.
13. Berry DB,. Mammalian central nervous system trace amines. Pharmacologic amphetamines, physiologic neuromodulators. J Neurochem. 2004; 90: 257-271.
14. Lashley KS,. Patterns of cerebral integration indicated by the scotomatas of migraine. Arch Neurol Psychiatry. 1941; 46: 331-339.
15. Lauritzen M, Skyhoj E, Olesen J, et al,. The role of spreading depression in acute brain disorders. Ann Neurol. 1981; 4: 569-572.
16. Van Gelder N,. Calcium mobility and release associated with EEG abnormalities, migraine and epilepsy. In:, Lugaresi AF, ed. Migraine and Epilepsy. Boston: Butterworths; 1987: 367-378.
17. Freeman M,. Reconsidering the effect of monosodium glutamate: A literature review. J Am Acad Nurse Pract. 2006; 18: 482-486.
18. D'Andrea G, Cananzi AR, Joseph R, et al,. Platelet glycine, glutamate, and aspartate in primary headache. Cephalalgia. 1991; 11: 197-200.
19. Ferrari MD, Odink J, Bos KD, Maleny MS, Bruin GW,. Neuroexcitatory plasma amino acids are elevated in migraine. Neurology. 1990; 40: 1582-1586.
20. Peres MF, Zukermann E, Senne Soares CA, Alonso EO, Santos BF, Faulhaber MH,. Cerebrospinal fluid glutamate levels in chronic migraine. Cephalalgia. 2004; 24: 735-739.
21. Aurora SK, Ahmad BK, Welch KM, Bhardhwaj P, Ramadan NM,. Transcranial magnetic stimulation confirms hyperexcitability of occipital cortex in migraine. Neurology. 1998; 50: 1111-1114.
22. Khedr EM, Ahmed MA, Mohamed KA,. Motor and visual cortical excitability in migraineurs patients with and without aura: Transcranial magnetic stimulation. Neurophysiol Clin. 2006; 36: 13-18.
23. Schoenen J,. Neurophysiological features of the migraineous brain. Neurol Sci. 2006; 27: S77-S81.
24. Ramadan NM, Halvorson H, Vande-Linde A, Levine SR, Helpern JA, Welch KM,. Low brain magnesium and migraine. Headache. 1989; 9: 416-419.
25. Van Harreveld A,. The nature of chick's magnesium sensitive retinal spreading depression. J Neurobiol. 1984; 15: 333-334.
26. Leach MJ, Lees G, Riddall DR,. Lamotrigine. Mechanisms of action. In:, Levy RH, Mattson RH, Meldrum BS, eds. Antiepileptic Drugs, 4th edn. New York: Raven Press; 1995: 851-859.
27. D'Andrea G, Granella F, Cadaldini M, Manzoni GC,. Effectiveness of lamotrigine in the prophylaxis. Cephalalgia. 1999; 19: 64-66.
28. Lampl C, Katsarava Z, Diener HC, Limmroth V,. Lamotrigine reduces migraine aura and migraine attacks in patients with migraine with aura. J Neurol Neurosurg Psychiatry. 2005; 76: 1730-1732.
29. Steiner TJ, Findley LJ, Yuen AW,. Lamotrigine versus placebo in the prophylaxis of migraine with and without aura. Cephalalgia. 1997; 17: 109-112.
30. Bogdanov VB, Multon S, Chauvel V, Bogdanova OV, Makarchuk MY, Schoenen J,. Cortical spreading depression and associated neuronal Fos expression in rats are affected differentially by chronic treatment with lamotrigine, valproate or riboflavin. Cephalalgia. 2009; 29: 10.
31. Griffin NJ, Ruggiero L, Lipton RB, Silberstein SD, et al,. Premonitory symptoms in migraine: An electronic diary study. Neurology. 2003; 25: 935-940.
32. Quintela E, Castillo J, Mnoz P, Pascual J,. Premonitory and resolution symptoms in migraine: A prospective study in 100 unselected patients. Cephalalgia. 2006; 26: 1051-1060.
33. Denuelle M, Fabre N, Payoux P, Chollet F, Geroud G,. Hypothalamic activation in spontaneous migraine attacks. Headache. 2007; 47: 1418-1426.
34. D'Andrea G, Terrazzino S, Leon A, et al,. Elevated levels of circulating trace amines in primary headaches. Neurology. 2004; 62: 1701-1705.
35. D'Andrea G, Granella F, Leone M, Perini F, Farruggio A, Bussone G,. Abnormal platelet trace amine profiles in migraine with and without aura. Cephalalgia. 2006; 26: 968-972.
36. Villalon CM, Olesen J,. The role of CGRP in the pathophysiology of migraine and efficacy of CGRP receptor antagonists as acute antimigraine drugs. Pharmacol Ther. 2009; 124: 309-323.
37. Perini F, D'Andrea G, Galloni E, et al,. Plasma cytokine levels in migraineurs and controls. Headache. 2005; 5: 926-931.
38. Bolay N, Reuter U, Dunn AK, Huang Z, Boas DA, Moskowitz MA,. Intrinsic brain activity triggers trigemional meningeal afferent in migraine model. Nat Med. 2002; 8: 136-142.
39. Moulton EA, Burstein R, Tully S, Hargreaves R, Becerra L, Borsok D,. Interictal dysfunction descending modulatory center in migraine patients. PLoS ONE. 2008; 3: e3799.
40. Fumal A, Laureys S, Di Clemente L, et al,. Orbitofrontal cortex involvement in chronic analgesic-overuse headache evolving from episodic migraine. Brain. 2006; 129: 543-550.
41. Welch KMA, Cao Y, Aurora SK, Wiggins G, Vikingstad EM,. MRI of the occipital cortex, red nucleus and substantia nigra during visual aura of migraine. Neurology. 1998; 51: 1465-1469.
42. Weiller C, May A, Limmroth V, et al,. Brain stem activation in spontaneous human migraine attacks. Nat Med. 1995; 1: 658-660.
43. Danielson TJ, Boulton AA, Robertson HS,. M-octopamine, p-octopamine and phenylethylamine in mammalian brain: A sensitive specific assay and the effect of drugs. J Neurochem. 1977; 29: 1131-1135.
44. D'Andrea G, Granella F, Perini F, Farruggio A, Leone M, Bussone G,. Platelet levels of dopamine are increased in migraine and cluster headache. Headache. 2006; 46: 585-591.
45. Gallai V, Gaiti A, Sarchielli P, Coata G, Trequattrini A, Paciaroni M,. Evidence for an altered dopamine β-hydroxylase activity in migraine and tension type headache. Acta Neurol Scand. 1992; 86: 403-446.
46. Martignoni F, Blandini F, D'Andrea G, et al,. Platelet and plasma catecholamines in migraine patients. Evidences of menstrual-related variability of the noradrenergic tone. Biogenic Amines. 1990; 10: 227-237.
47. Fernandez F, Lea RA, Colson NJ, Bellis C, Quinlan S, Griffits LR,. Association between a 19 bp deletion polymorphism at dopamine beta-hydroxylase (DBH) locus and migraine with aura. J Neurol Sci. 2006; 251: 118-123.
48. Peroutka JP,. Migraine: A chronic sympathetic nervous system disorder. Headache. 2004; 44: 53-64.
49. Lambert GA, Truong L, Zagami A,. Effect of cortical spreading depression on basal and evoked traffic in the trigeminovascular sensory system. Cephalalgia. 2011; 31: 1439-1451.
50. Sicuteri F, Testi A, Anselmi B,. Biochemical investigations in headache: Increase of hydroyindoleacetic acid excretion during migraine attack. Int Arch Allergy. 1961; 19: 265-271.
51. D'Andrea G, Hasselmark L, Cananzi AR, et al,. Metabolism and menstrual cycle rhythmicity of serotonin in primary headaches. Headache. 1995; 35: 216-221.
52. Fioroni L, D'Andrea G, Alecci M, Cananzi AR, Facchinetti F,. Platelet serotonin pathway in menstrual migraine. Cephalalgia. 1996; 16: 427-430.
53. Casucci G, Villani V, Frediani F,. Central mechanism of action of antimigraine prophylactic drugs. Neurol Sci. 2008; 29 (Suppl. 1): S123-S126.
54. Welch KMA, Chabi E, Nell JH, Bartosh K, Achar VS, Meyer JS,. Cerebrospinal fluid gamma aminobutyric acid levels and migraine. Br Med J. 1975; 3: 516-517.
55. Joseph R, D'Andrea G, Grunfeld S, Welch KMA,. Cytosolic ionized calcium homeostasis in platelet: An abnormal sensitivity to PAF-activation in migraine. Headache. 1988; 28: 396-402.
56. D'Andrea G, Welch KMA, Riddle JM, Grunfeld S, Joseph R,. Platelet serotonin metabolism and ultrastructure in migraine. Arch Neurol. 1989; 46: 1187-1189.
57. Joseph R, Welch KMA, Levine S, D'Andrea G,. ATP hyposecretion from platelet dense bodies-evidence for the purinergic hypothesis and a marker of migraine. Headache. 1986; 26: 403-410.
58. Sangiorgi S, Mochi M, Riva R, et al,. Abnormal platelet mitochondrial function in patients affected by migraine with and without aura. Cephalalgia. 1994; 14: 31-23.
59. Welch KMA, Ramadan MN,. Mitochondria, magnesium and migraine. J Neurol Sci. 1995; 134: 9-14.
60. Balbi T, Fusco M, Vasapollo D, et al,. The presence of trace amines in postmortem cerebrospinal fluid in humans. J Forensic Sci. 2005; 50: 630-632.
61. Welch KMA,. Iron in the migraine brain: A resilient hypothesis. Cephalalgia. 2009; 29: 283-285.
62. Su L, Wang C, Ren YY, Xie KL, Wang GL,. Role of TRPM8 in dorsal root ganglion in nerve injury-induced chronic pain. BMC Neurosci. 2011; 12: 120-135.