Dual labeling of biomolecules using MeCAT and DOTA derivatives: Application to quantitative proteomics

Analytical and Bioanalytical Chemistry

Volumn 403, Issue 8, 2012, Pages 2255-2267

  El Khatib, Ahmed H ^a   Esteban Fernández, Diego ^a   Linscheid, Michael W ^a  

^a HUMBOLDT UNIVERSITY   (Germany)

Author keywords

Amino and thiol labeling; DOTA NHS; ICP MS; MeCAT; On resin labeling; Peptide protein quantification

Indexed keywords

1 , 4 , 7 , 10-TETRAAZACYCLODODECANE- 1 , 4 , 7 , 10-TETRAACETIC ACID; AFFINITY TAGS; BOVINE SERUM ALBUMINS; DOTA-NHS; HUMAN SERUM ALBUMINS; ICP-MS; LABELING STEPS; LINEAR CALIBRATION; LIQUID CHROMATOGRAPHY ELECTROSPRAY; MECAT; METALLATION; PARALLEL DETECTION; PRE-CONCENTRATION; PROOF OF CONCEPT; QUANTITATIVE INFORMATION; QUANTITATIVE PROTEOMICS; STANDARD ADDITION; THIOL GROUPS;

AMINO ACIDS; INDUCTIVELY COUPLED PLASMA MASS SPECTROMETRY; LIQUID CHROMATOGRAPHY; MASS SPECTROMETERS; MOLECULAR BIOLOGY; RARE EARTH ELEMENTS; RESINS; STOICHIOMETRY;

PEPTIDES;

AMINE; BOVINE SERUM ALBUMIN; CYSTEINE; DOTA NHS; DOTA-NHS; LANTHANIDE; PEPTIDE; SERUM ALBUMIN; SUCCINIMIDE DERIVATIVE; THIOL DERIVATIVE;

AFFINITY LABELING; AMINO ACID SEQUENCE; ANIMAL; ARTICLE; CATTLE; CHEMISTRY; ELECTROSPRAY MASS SPECTROMETRY; HUMAN; LIQUID CHROMATOGRAPHY; METHODOLOGY; MOLECULAR GENETICS; PROTEOMICS; STAINING;

AFFINITY LABELS; AMINES; AMINO ACID SEQUENCE; ANIMALS; CATTLE; CHROMATOGRAPHY, LIQUID; CYSTEINE; HUMANS; LANTHANOID SERIES ELEMENTS; MOLECULAR SEQUENCE DATA; PEPTIDES; PROTEOMICS; SERUM ALBUMIN; SERUM ALBUMIN, BOVINE; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; STAINING AND LABELING; SUCCINIMIDES; SULFHYDRYL COMPOUNDS;

BOVINAE;

EID: 84863722140     PISSN: 16182642     EISSN: 16182650     Source Type: Journal    
DOI: 10.1007/s00216-012-5910-1     Document Type: Article

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