메뉴 건너뛰기




Volumn 19, Issue 7, 2012, Pages 489-498

Enhanced antitumor effect of cisplatin in human NSCLC cells by tumor suppressor LKB1

Author keywords

cisplatin; combination therapy; LKB1; lung cancer

Indexed keywords

CISPLATIN; GELATINASE A; GELATINASE B; MAMMALIAN TARGET OF RAPAMYCIN; PROTEIN KINASE LKB1; PROTEIN P53; STRESS ACTIVATED PROTEIN KINASE;

EID: 84863721162     PISSN: 09291903     EISSN: 14765500     Source Type: Journal    
DOI: 10.1038/cgt.2012.18     Document Type: Article
Times cited : (23)

References (37)
  • 4
    • 79955006086 scopus 로고    scopus 로고
    • Lung cancer: New biological insights and recent therapeutic advances
    • Ramalingam SS, Owonikoko TK, Khuri FR. Lung cancer: new biological insights and recent therapeutic advances. CA Cancer J Clin 2011; 61: 91-112.
    • (2011) CA Cancer J Clin , vol.61 , pp. 91-112
    • Ramalingam, S.S.1    Owonikoko, T.K.2    Khuri, F.R.3
  • 5
    • 0028843552 scopus 로고
    • Chemotherapy in non-small cell lung cancer: A meta-analysis using updated data on individual patients from 52 randomized clinical trials
    • Non-Small Cell Lung Cancer Collaborative Group
    • Non-Small Cell Lung Cancer Collaborative Group. Chemotherapy in non-small cell lung cancer: a meta-analysis using updated data on individual patients from 52 randomized clinical trials. Br Med J 1995; 311: 899-909.
    • (1995) Br Med J , vol.311 , pp. 899-909
  • 6
    • 33750069402 scopus 로고    scopus 로고
    • Advances in chemotherapy of non-small cell lung cancer
    • DOI 10.1378/chest.130.4.1211
    • Molina JR, Adjei AA, Jett JR. Advances in chemotherapy of non-small cell lung cancer. Chest 2006; 13: 1211-1219. (Pubitemid 44583755)
    • (2006) Chest , vol.130 , Issue.4 , pp. 1211-1219
    • Molina, J.R.1    Adjei, A.A.2    Jett, J.R.3
  • 7
    • 0033996533 scopus 로고    scopus 로고
    • Evolution of cisplatin-based chemotherapy in non-small cell lung cancer
    • Johnson DH. Evolution of cisplatin-based chemotherapy in non-small cell lung cancer. Chest 2000; 117: 133s-137s.
    • (2000) Chest , vol.117
    • Johnson, D.H.1
  • 8
    • 84863719233 scopus 로고    scopus 로고
    • Single nucleotide polymorphisms in the p53 pathway
    • Levine A. Single nucleotide polymorphisms in the p53 pathway. FEBS J 2009; 27: 61-61.
    • (2009) FEBS J , vol.27 , pp. 61-61
    • Levine, A.1
  • 11
    • 37149046928 scopus 로고    scopus 로고
    • Enhancement of antitumor activity of cisplatin in human lung cancer cells by tumor suppressor FUS1
    • DOI 10.1038/sj.cgt.7701094, PII 7701094
    • Deng WG, Wu G, Ueda K, Xu K, Roth JA, Ji L. Enhancement of antitumor activity of cisplatin in human lung cancer cells by tumor suppressor FUS1. Cancer Gen Ther 2008; 15: 29-39. (Pubitemid 350261296)
    • (2008) Cancer Gene Therapy , vol.15 , Issue.1 , pp. 29-39
    • Deng, W.-G.1    Wu, G.2    Ueda, K.3    Xu, K.4    Roth, J.A.5    Ji, L.6
  • 12
    • 50249143902 scopus 로고    scopus 로고
    • Role of LKB1 in lung cancer development
    • Makowski L, Hayes DN. Role of LKB1 in lung cancer development. Br J Cancer 2008; 99: 683-688.
    • (2008) Br J Cancer , vol.99 , pp. 683-688
    • Makowski, L.1    Hayes, D.N.2
  • 13
    • 45549086246 scopus 로고    scopus 로고
    • LKB1 and lung cancer: More than the usual suspects
    • Shah U, Sharpless NE, Hayes DN. LKB1 and lung cancer: more than the usual suspects. Cancer Res 2008; 68: 3562-3565.
    • (2008) Cancer Res , vol.68 , pp. 3562-3565
    • Shah, U.1    Sharpless, N.E.2    Hayes, D.N.3
  • 15
    • 48249102662 scopus 로고    scopus 로고
    • Mutations in the LKB1 tumour suppressor are frequently detected in tumours from Caucasian but not Asian lung cancer patients
    • Koivunen JP, Kim J, Lee J, Rogers AM, Park JO, Zhao X et al. Mutations in the LKB1 tumour suppressor are frequently detected in tumours from Caucasian but not Asian lung cancer patients. Br J Cancer 2008; 99: 245-252.
    • (2008) Br J Cancer , vol.99 , pp. 245-252
    • Koivunen, J.P.1    Kim, J.2    Lee, J.3    Rogers, A.M.4    Park, J.O.5    Zhao, X.6
  • 16
    • 79953232702 scopus 로고    scopus 로고
    • LKB1 in lung cancerigenesis: A serine/threonine kinase as tumor suppressor
    • Gao Y, Ge G, Ji H. LKB1 in lung cancerigenesis: a serine/threonine kinase as tumor suppressor. Protein Cell 2011; 2: 99-107.
    • (2011) Protein Cell , vol.2 , pp. 99-107
    • Gao, Y.1    Ge, G.2    Ji, H.3
  • 17
    • 77953238558 scopus 로고    scopus 로고
    • Integrative genomic and proteomic analyses identify targets for LKB1-deficient metastatic lung tumours
    • Carretero J, Shimamura T, Rikova K, Jackson AL, Wilkerson MD, Borgman C et al. Integrative genomic and proteomic analyses identify targets for LKB1-deficient metastatic lung tumours. Cancer Cell 2010; 17: 547-559.
    • (2010) Cancer Cell , vol.17 , pp. 547-559
    • Carretero, J.1    Shimamura, T.2    Rikova, K.3    Jackson, A.L.4    Wilkerson, M.D.5    Borgman, C.6
  • 19
    • 64249128769 scopus 로고    scopus 로고
    • The molecular mechanisms that underlie the tumor suppressor function of LKB1
    • Fan D, Ma C, Zhang H. The molecular mechanisms that underlie the tumor suppressor function of LKB1. Acta Biochim Biophys Sin 2009; 41: 97-107.
    • (2009) Acta Biochim Biophys Sin , vol.41 , pp. 97-107
    • Fan, D.1    Ma, C.2    Zhang, H.3
  • 20
    • 79953248896 scopus 로고    scopus 로고
    • Molecular mechanisms of tumor suppression by LKB1
    • Vaahtomeri K, Mäkelä TP. Molecular mechanisms of tumor suppression by LKB1. FEBS Lett 2011; 585: 944-951.
    • (2011) FEBS Lett , vol.585 , pp. 944-951
    • Vaahtomeri, K.1    Mäkelä, T.P.2
  • 21
    • 77953329903 scopus 로고    scopus 로고
    • Improved tumor-targeting drug delivery and therapeutic efficacy by cationic liposome modified with truncated bFGF peptide
    • Chen X, Wang X, Wang Y, Yang L, Hu J, Xiao W et al. Improved tumor-targeting drug delivery and therapeutic efficacy by cationic liposome modified with truncated bFGF peptide. J Control Release 2010; 145: 17-25.
    • (2010) J Control Release , vol.145 , pp. 17-25
    • Chen, X.1    Wang, X.2    Wang, Y.3    Yang, L.4    Hu, J.5    Xiao, W.6
  • 22
    • 77953695990 scopus 로고    scopus 로고
    • The Wnt inhibitory factor 1 restoration in prostate cancer cells was associated with reduced tumor growth, decreased capacity of cell migration and invasion and a reversal of epithelial to mesenchymal transition
    • Yee DS, Tang Y, Li X, Liu Z, Guo Y, Ghaffar S et al. The Wnt inhibitory factor 1 restoration in prostate cancer cells was associated with reduced tumor growth, decreased capacity of cell migration and invasion and a reversal of epithelial to mesenchymal transition. Mol Cancer 2010; 9: 162-175.
    • (2010) Mol Cancer , vol.9 , pp. 162-175
    • Yee, D.S.1    Tang, Y.2    Li, X.3    Liu, Z.4    Guo, Y.5    Ghaffar, S.6
  • 23
    • 0033782775 scopus 로고    scopus 로고
    • Immunotherapy of tumors with xenogeneic endothelial cells as a vaccine
    • Wei YQ, Wang QR, Zhao X, Yang L, Tian L, Lu Y et al. Immunotherapy of tumors with xenogeneic endothelial cells as a vaccine. Nat Med 2000; 6: 1160-1166.
    • (2000) Nat Med , vol.6 , pp. 1160-1166
    • Wei, Y.Q.1    Wang, Q.R.2    Zhao, X.3    Yang, L.4    Tian, L.5    Lu, Y.6
  • 24
    • 48749099976 scopus 로고    scopus 로고
    • Inhibition of mTOR restores cisplatin sensitivity through down-regulation of growth and antiapoptotic proteins
    • Wangpaichitr M, Wu C, You M, Kuo MT, Feun L, Lampidis T et al. Inhibition of mTOR restores cisplatin sensitivity through down-regulation of growth and antiapoptotic proteins. Eur J Phar 2008; 591: 124-127.
    • (2008) Eur J Phar , vol.591 , pp. 124-127
    • Wangpaichitr, M.1    Wu, C.2    You, M.3    Kuo, M.T.4    Feun, L.5    Lampidis, T.6
  • 25
    • 69949109923 scopus 로고    scopus 로고
    • MTOR is a promising therapeutic target both in cisplatin-sensitive and cisplatin-resistant clear cell carcinoma of the ovary
    • Mabuchi S, Kawase C, Altomare DA, Morishige K, Sawada K, Hayashi M et al. mTOR is a promising therapeutic target both in cisplatin-sensitive and cisplatin-resistant clear cell carcinoma of the ovary. Clin Cancer Res 2009; 15: 5404-5413.
    • (2009) Clin Cancer Res , vol.15 , pp. 5404-5413
    • Mabuchi, S.1    Kawase, C.2    Altomare, D.A.3    Morishige, K.4    Sawada, K.5    Hayashi, M.6
  • 26
    • 34249321653 scopus 로고    scopus 로고
    • Mechanisms of resistance to cisplatin and carboplatin
    • DOI 10.1016/j.critrevonc.2007.02.001, PII S1040842807000340
    • Stewart DJ. Mechanisms of resistance to cisplatin and carboplatin. Crit Rev Oncol Hematol 2007; 63: 12-31. (Pubitemid 46810280)
    • (2007) Critical Reviews in Oncology/Hematology , vol.63 , Issue.1 , pp. 12-31
    • Stewart, D.J.1
  • 27
    • 0029835487 scopus 로고    scopus 로고
    • Gene therapy for lung cancer: Enhancement of tumor suppression by a combination of sequential systemic cisplatin and adenovirus-mediated p53 gene transfer
    • Nguyen DM, Spitz FR, Yen N, Cristiano RJ, Roth JA. Gene therapy for lung cancer: enhancement of tumor suppression by a combination of sequential systemic cisplatin and adenovirus-mediated p53 gene transfer. J Thorac Cardiovasc Surg 1996; 112: 1372-1377. (Pubitemid 26403437)
    • (1996) Journal of Thoracic and Cardiovascular Surgery , vol.112 , Issue.5 , pp. 1372-1377
    • Nguyen, D.M.1    Spitz, F.R.2    Yen, N.3    Cristiano, R.J.4    Roth, J.A.5    Kaiser, L.R.6    Kim, J.7
  • 28
    • 67749111502 scopus 로고    scopus 로고
    • The LKB1-AMPK pathway: Metabolism and growth control in tumor suppression
    • Shackelford DB, Shaw RJ. The LKB1-AMPK pathway: metabolism and growth control in tumor suppression. Nat Rev Cancer 2009; 9: 563-575.
    • (2009) Nat Rev Cancer , vol.9 , pp. 563-575
    • Shackelford, D.B.1    Shaw, R.J.2
  • 29
    • 70349565231 scopus 로고    scopus 로고
    • SIK1 couples LKB1 to p53-depengdent anoikis and suppresses metastasis
    • Cheng H, Liu P, Wang ZC, Zou L, Santiago S, Garbitt V et al. SIK1 couples LKB1 to p53-depengdent anoikis and suppresses metastasis. Sci Signal 2009; 2: 1-11.
    • (2009) Sci Signal , vol.2 , pp. 1-11
    • Cheng, H.1    Liu, P.2    Wang, Z.C.3    Zou, L.4    Santiago, S.5    Garbitt, V.6
  • 30
    • 33745212865 scopus 로고    scopus 로고
    • JNK pathway mediates apoptotic cell death induced by tumor suppressor LKB1 in Drosophila
    • DOI 10.1038/sj.cdd.4401790, PII 4401790
    • Lee JH, Koh H, Kim M, Park J, Lee SY, Lee S et al. JNK pathway mediates apoptotic cell death induced by tumor suppressor LKB1 in Drosophila. Cell Death Differ 2006; 13: 1110-1122. (Pubitemid 43905592)
    • (2006) Cell Death and Differentiation , vol.13 , Issue.7 , pp. 1110-1122
    • Lee, J.H.1    Koh, H.2    Kim, M.3    Park, J.4    Lee, S.Y.5    Lee, S.6    Chung, J.7
  • 32
    • 0345643514 scopus 로고    scopus 로고
    • Regulation of matrix metalloproteinase expression in tumor invasion
    • Westermarck J, Kähäri M. Regulation of matrix metalloproteinase expression in tumor invasion. FASEB J 1999; 13: 781-792. (Pubitemid 29220691)
    • (1999) FASEB Journal , vol.13 , Issue.8 , pp. 781-792
    • Westermarck, J.1    Kahari, V.-M.2
  • 33
    • 0032904304 scopus 로고    scopus 로고
    • Loss of basement membrane type IV collagen is associated with increased expression of metalloproteinases 2 and 9 (MMP-2 and MMP-9) during human colorectal tumorigenesis
    • Zeng ZS, Cohen AM, Guillem JG. Loss of basement membrane type Iv collagen is associated with increased expression of metalloproteinases 2 and 9 (MMP-2 and MMP-9) during human colorectal tumorigenesis. Carcinogenesis 1999; 20: 749-755. (Pubitemid 29191855)
    • (1999) Carcinogenesis , vol.20 , Issue.5 , pp. 749-755
    • Zeng, Z.-S.1    Cohen, A.M.2    Guillem, J.G.3
  • 34
    • 77955858619 scopus 로고    scopus 로고
    • Cisplatin and PI3kinase inhibition decrease invasion and migration of human ovarian carcinoma cells and regulate matrix-metalloproteinase expression
    • Karam AK, Santiskulvong C, Fekete M, Zabih S, Eng C, Dorigo O. Cisplatin and PI3kinase inhibition decrease invasion and migration of human ovarian carcinoma cells and regulate matrix-metalloproteinase expression. Cytoskeleton (Hoboken) 2010; 67: 535-544.
    • (2010) Cytoskeleton (Hoboken) , vol.67 , pp. 535-544
    • Karam, A.K.1    Santiskulvong, C.2    Fekete, M.3    Zabih, S.4    Eng, C.5    Dorigo, O.6
  • 37
    • 84863723396 scopus 로고    scopus 로고
    • Enhanced expression of LKB1 in breast cancer cells attenuates angiogenesis, invasion, and metastatic potential
    • Zhuang ZG, Di GH, Shen ZZ, Ding J, Shao ZM. Enhanced expression of LKB1 in breast cancer cells attenuates angiogenesis, invasion, and metastatic potential. Mol Cancer Res 2006; 66: 7870-7879.
    • (2006) Mol Cancer Res , vol.66 , pp. 7870-7879
    • Zhuang, Z.G.1    Di, G.H.2    Shen, Z.Z.3    Ding, J.4    Shao, Z.M.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.