Synthesis, antitumor, and antibacterial activity of Bis[4,5-diarylimidazol- 2-ylidene]methane derivatives

Archiv der Pharmazie

Volumn 345, Issue 7, 2012, Pages 557-564

  Liu, Wukun ^a   Chen, Xiaohua ^b   Gust, Ronald ^a,c  

^a FREIE UNIVERSITÄT BERLIN   (Germany)

^b HUMBOLDT UNIVERSITY   (Germany)

^c UNIVERSITY OF INNSBRUCK   (Austria)

Author keywords

Antibacterial activity; Antitumor activity; Gold bisNHC complexes; Methylene bridged imidazoles

Indexed keywords

ANTIINFECTIVE AGENT; ANTINEOPLASTIC AGENT; BIS (1,3 DIETHYL 4,5 DIARYLIMIDAZOL 2 YLIDENE) METHANE DERIVATIVE; BIS [1 ETHYL 4,5 BIS (4 HYDROXYPHENYL) 1H IMIDAZOL 2 YL] METHANE; BIS [1 ETHYL 4,5 BIS (4 METHOXYPHENYL) 1H IMIDAZOL 2 YL] METHANE; BIS [1 ETHYL 4,5 BIS (4 METHOXYPHENYL) 1H IMIDAZOL 2 YL] METHANONE; BIS [1,3 DIETHYL 4,5 BIS (4 HYDROXYPHENYL) IMIDAZOL 2 YLIDENE] METHANE DIBROMIDE; BIS [1,3 DIETHYL 4,5 BIS (4 METHOXYPHENYL) IMIDAZOL 2 YLIDENE] METHANE DIBROMIDE; BIS [4,5 DIARYLIMIDAZOL 2 YLIDENE] METHANE DERIVATIVE; CARBENE; GOLD COMPLEX; IMIDAZOLE DERIVATIVE; UNCLASSIFIED DRUG;

ANTIBACTERIAL ACTIVITY; ANTINEOPLASTIC ACTIVITY; ARTICLE; BACTERIAL GROWTH; CANCER INHIBITION; CARCINOMA CELL; CONTROLLED STUDY; CYTOTOXICITY; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HUMAN CELL; IC 50; IN VITRO STUDY; PRIORITY JOURNAL;

ANTI-BACTERIAL AGENTS; ANTINEOPLASTIC AGENTS; BACILLUS MEGATERIUM; BACILLUS SUBTILIS; CELL CULTURE TECHNIQUES; CELL PROLIFERATION; CELL SURVIVAL; CRYSTALLOGRAPHY, X-RAY; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG DESIGN; ERWINIA AMYLOVORA; ESCHERICHIA COLI; HT29 CELLS; HUMANS; IMIDAZOLES; MICROBIAL SENSITIVITY TESTS; MOLECULAR STRUCTURE; TIME FACTORS;

EID: 84863696624     PISSN: 03656233     EISSN: 15214184     Source Type: Journal    
DOI: 10.1002/ardp.201100474     Document Type: Article

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