Variants of the ankyrin repeat domain 6gene (ANKRD6) and muscle and physical activity phenotypes among European-derived American adults

Journal of Strength and Conditioning Research

Volumn 26, Issue 7, 2012, Pages 1740-1748

  Van Deveire, Katherine N ^a   Angelopoulos, Theodore J ^b   Visich, Paul S ^f   Scranton, Sarah K ^a   Clarkson, Priscilla M ^c   Zoeller, Robert F ^g   Gordish Dressman, Heather ⁱ   Kostek, Mathew A ^a   Thompson, Paul D ^h   Hoffman, Eric P ⁱ   Gordon, Paul M ^d   Moyna, Niall M ^e   Devaney, Joseph M ⁱ   Maresh, Carl M ^a   Pescatello, Linda S ^a  

^a UNIVERSITY OF CONNECTICUT   (United States)

^b UNIVERSITY OF CENTRAL FLORIDA   (United States)

^c UNIVERSITY OF MASSACHUSETTS   (United States)

^d UNIVERSITY OF MICHIGAN   (United States)

^e DUBLIN CITY UNIVERSITY   (Ireland)

^f CENTRAL MICHIGAN UNIVERSITY   (United States)

^g FLORIDA ATLANTIC UNIVERSITY   (United States)

^h HARTFORD HOSPITAL   (United States)

ⁱ CHILDREN'S NATIONAL MEDICAL CENTER   (United States)

Author keywords

Diversin; Exercise; Genetics; Resistance training

Indexed keywords

ANKRD6 PROTEIN, HUMAN; CYTOSKELETON PROTEIN;

ADOLESCENT; ADULT; ARTICLE; CAUCASIAN; FEMALE; GENETICS; GENOTYPE; HISTOLOGY; HUMAN; MALE; MOTOR ACTIVITY; MULTIVARIATE ANALYSIS; MUSCLE STRENGTH; PHENOTYPE; PHYSIOLOGY; QUESTIONNAIRE; RESISTANCE TRAINING; SINGLE NUCLEOTIDE POLYMORPHISM; SKELETAL MUSCLE; UNITED STATES;

ADOLESCENT; ADULT; CYTOSKELETAL PROTEINS; EUROPEAN CONTINENTAL ANCESTRY GROUP; FEMALE; GENOTYPE; HUMANS; MALE; MOTOR ACTIVITY; MULTIVARIATE ANALYSIS; MUSCLE STRENGTH; MUSCLE, SKELETAL; PHENOTYPE; POLYMORPHISM, SINGLE NUCLEOTIDE; QUESTIONNAIRES; RESISTANCE TRAINING; UNITED STATES; YOUNG ADULT;

EID: 84863684233     PISSN: 10648011     EISSN: None     Source Type: Journal    
DOI: 10.1519/JSC.0b013e31825c2bef     Document Type: Article

References (32)

1. Ainsworth, BE, Leon, AS, Richardson, MT, Jacobs, DR, and Paffenbarger, RS Jr. Accuracy of the college alumnus physical activity questionnaire. J Clin Epidemiol 46: 1403-1411, 1993.
2. Bennett, V and Baines, AJ. Spectrin and ankyrin-based pathways: Metazoan inventions for integrating cells into tissues. Physiol Rev 81: 1353-1392, 2001.
3. Bouchard, C, Dionne, FT, Simoneau, JA, and Boulay, MR. Genetics of aerobic and anaerobic performances. Exerc Sport Sci Rev 20: 27-58, 1992.
4. Carlsson, S, Andersson, T, Lichtenstein, P, Michaelsson, K, and Ahlbom, A. Genetic effects on physical activity: Results from the Swedish Twin Registry. Med Sci Sports Exer 38: 1396-1401, 2006.
5. Clevers, H. Wnt/beta-catenin signaling in development and disease. Cell 127: 469-480, 2006.
6. De Mars, G, Windelinckx, A, Beunen, G, Delecluse, C, Lefevre, J, and Thomis, MA. Polymorphisms in the CNTF and CNTF receptor genes are associated with muscle strength in men and women. J Appl Physiol 102: 1824-1831, 2007.
7. De Moor, MH, Liu, YJ, Boomsma, DI, Li, J, Hamilton, JJ, Hottenga, JJ, Levy, S, Liu, XG, Pei, YF, Posthuma, D, Recker, RR, Sullivan, PF, Wang, L, Willemsen, G, Yan, H, De Geus, EJC, and Deng, HW. Genome-wide association study of exercise behavior in Dutch and American adults. Med Sci Sports Exerc 41: 1887-1895, 2009.
8. De Moor, MH, Posthuma, D, Hottenga, JJ, Willemsen, G, Boomsma, DI, and De Geus, EJ. Genome-wide linkage scan for exercise participation in Dutch sibling pairs. Eur J Hum Genet 15: 1252-1259, 2007.
9. Hubal, MJ, Gordish-Dressman, H, Thompson, PD, Hoffman, EP, Angelopoulos, TJ, Gordon, PM, Moyna, NM, Pescatello, LS, Visich, PS, Zoeller, RF, Seip, RL, and Clarkson, PM. Variability in muscle size and strength gain after unilateral resistance training. Med Sci Sports Exerc 37: 964-972, 2005.
10. International HapMap Consortium, Frazer, KA and Ballinger, DG, et al. A second generation human haplotype map of over 3.1 million SNPs. Nature 449: 851-861, 2007.
11. Joosen, AM, Gielen, M, Vlietinck, R, and Westerterp, KR. Genetic analysis of physical activity in twins. Am J Clin Nutr 82: 1253-1259, 2005.
12. Knab, AM, Bowen, RS, Hamilton, AT, Gulledge, AA, and Lightfoot, JT. Altered dopaminergic profiles: Implications for the regulation of voluntary physical activity. Behav Brain Res 204: 147-152, 2009.
13. Kostek, MA, Angelopoulos, TJ, Clarkson, PM, Gordon, PM, Moyna, NM, Visich, PS, Zoeller, RF, Price, TB, Seip, RL, Thompson, PD, Devaney, JM, Gordish-Dressman, H, Hoffman, EP, and Pescatello, LS. Myostatin and follistatin polymorphisms interact with muscle phenotypes and ethnicity. Med Sci Sports Exerc 41: 1063-1071, 2009.
14. Lightfoot, JT. Current understanding of the genetic basis for physical activity. J Nutr 141; 526-530, 2011.
15. Moeller, H, Jenny, A, Schaeffer, HJ, Schwarz-Romond, T, Mlodzik, M, Hammerschmidt, M, and Birchmeier, W. Diversin regulates heart formation and gastrulation movements in development. Pro Natl Acad Sci U S A 103: 15900-15905, 2006.
16. Paffenbarger, RS Jr,Wing, AL, and Hyde, RT. Physical activity as an index of heart attack risk in college alumni. Am J Epidemiol 108: 161-175, 1978.
17. Paffenbarger, RS Jr, Blair, SN, Lee, IM, and Hyde, RT. Measurement of physical activity to assess health effects in free-living populations. Med Sci Sports Exerc 25: 60-70, 1993.
18. Pate, RR, Pratt, M, Blair, SN, Haskell, WL, Macera, CA, Bouchard, C, Buchner, D, Ettinger, W, Heath, GW, King, AC, Kriska, A, Leon, AS, Marcus, BH, Morris, J, Paffenbarger, RS Jr, Patrick, K, Pollock, ML, Rippe, JM, Sallis, J, and Wilmore, JH. Physical activity and public health: A recommendation from the Centers for Disease Control and Prevention and the American College of Sports Medicine. JAMA 273: 402-407, 1995.
19. Perusse, L, Lortie, G, Leblanc, C, Tremblay, A, Theriault, G, and Bouchard, C. Genetic and environmental sources of variation in physical fitness. Ann Hum Biol 14: 425-434, 1987.
20. Pescatello, LS. The promises and challenges of the use of genomics in the prescription of exercise for hypertension. Curr Hypertens Rev 6: 32-34, 2010.
21. Pescatello, LS, Kostek, MA, Gordish-Dressman, H, Thompson, PD, Seip, RL, Price, TB, Angelopoulos, TJ, Clarkson, PM, Gordon, PM, Moyna, NM, Visich, PS, Zoeller, RF, Devaney, JM, and Hoffman, EP. ACE ID genotype and the muscle strength and size response to unilateral resistance training. Med Sci Sports Exerc 38: 1074-1081, 2006.
22. Pescatello, LS and Roth, SM. Molecular and Translational Medicine Series Volume: Exercise Genomics. New York, NY: Humana Press, 2011. ISBN 978-1-60761-354-1. http://dx.doi.org/10.1007/978-1-60761-355-8.
23. Rhodes, JS and Garland, T Jr. Differential sensitivity to acute administration of Ritalin, apomorphine, SCH 23390, but not raclopride in mice selectively bred for hyperactive wheel-running behavior. Psychopharmacology (Berl) 167: 242-250, 2003.
24. Schwarz-Romond, T, Asbrand, C, Bakkers, J, Kuhl, M, Schaeffer, HJ, Huelsken, J, Behrens, J, Hammerschmidt, M, and Birchmeier, W. The ankyrin repeat protein diversin recruits casein kinase iepsilon to the beta-catenin degradation complex and acts in both canonical wnt and Wnt/JNK signaling. Genes Dev 16: 2073-2084, 2002.
25. Simonen, R, Levalahti, E, Kaprio, J, Videman, T, and Battie, MC. Multivariate genetic analysis of lifetime exercise and environmental factors. Med Sci Sports Exerc 36: 1559-1566, 2004.
26. Stubbe, JH, Boomsma, DI, Vink, JM, Cornes, BK, Martin, NG, Skytthe, A, Kyvik, KO, Rose, RJ, Kujala, UM, Kaprio, J, Harris, JR, Pederson, NL, Hunkin, J, Spector, TD, and de Geus, EJC. Genetic influences on exercise participation in 37,051 twin pairs from seven countries. PLoS One 1: e22, 2006.
27. Thomis, MA, Beunen, GP, Van Leemputte, M, Maes, HH, Blimkie, CJ, Claessens, AL, Marchal, G, Willems, E, and Vlietinck, RF. Inheritance of static and dynamic arm strength and some of its determinants. Acta Physiol Scand 163: 59-71, 1998.
28. Thomis, MA, Beunen, GP, Maes, HH, Blimkie, CJ, Van Leemputte, M, Claessens, AL, Marchal, G, Willems, E, and Vlietinck, RF. Strength training: Importance of genetic factors. Med Sci Sports Exerc 30: 724-731, 1998.
29. Thompson, PD, Moyna, N, Seip, R, Price, T, Clarkson, P, Angelopoulos, T, Gordon, P, Pescatello, LS, Visich, P, Zoeller, R, Devaney, JM, Gordish, H, Bilbie, S, and Hoffman, EP. Functional polymorphisms associated with human muscle size and strength. Med Sci Sports Exerc 36: 1132-1139, 2004.
30. Tissir, F, Bar, I, Goffinet, AM, and Lambert De Rouvroit, C. Expression of the ankyrin repeat domain 6 gene (ANKRD6) during mouse brain development. Dev Dyn 224: 465-469, 2002.
31. Urso, ML. Is it time to change the ground rules of exerciserelated genomics research? Med Sci Sports Exerc 43: 753-754, 2011.
32. Walsh, S, Kelsey, BK, Angelopoulos, TJ, Clarkson, PM, Gordon, PM, Moyna, NM, Visich, PS, Zoeller, RF, Seip, RL, Bilbie, S, Thompson, PD, Hoffman, EP, Price, TB, Devaney, JM, and Pescatello, LS. CNTF 1357 G . A polymorphism and the muscle strength response to resistance training. J Appl Physiol 107: 1235-1240, 2009.