CNTF 1357 G → A polymorphism and the muscle strength response to resistance training

Journal of Applied Physiology

Volumn 107, Issue 4, 2009, Pages 1235-1240

  Walsh, Sean ^a   Kelsey, Bethany K ^b   Angelopoulos, Theodore J ^c   Clarkson, Priscilla M ^d   Gordon, Paul M ^e   Moyna, Niall M ^f   Visich, Paul S ^g   Zoeller, Robert F ^h   Seip, Richard L ⁱ   Bilbie, Steve ⁱ   Thompson, Paul D ⁱ   Hoffman, Eric P ^a   Price, Thomas B ^i,k   Devaney, Joseph M ^j   Pescatello, Linda S ^b  

^a CENTRAL CONNECTICUT STATE UNIVERSITY   (United States)

^b UNIVERSITY OF CONNECTICUT   (United States)

^c UNIVERSITY OF CENTRAL FLORIDA   (United States)

^d UNIVERSITY OF MASSACHUSETTS   (United States)

^e UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^f DUBLIN CITY UNIVERSITY   (Ireland)

^g CENTRAL MICHIGAN UNIVERSITY   (United States)

^h FLORIDA ATLANTIC UNIVERSITY   (United States)

ⁱ HARTFORD HOSPITAL   (United States)

^j CHILDREN'S NATIONAL MEDICAL CENTER   (United States)

^k YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

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Author keywords

Ciliary neurotrophic factor; Exercise; Genomics; Muscle mass

Indexed keywords

CILIARY NEUTROPHIC FACTOR; NEUROTROPHIC FACTOR; UNCLASSIFIED DRUG;

ADULT; ALLELE; ALLOMETRY; ARTICLE; BICEPS BRACHII MUSCLE; CONTROLLED STUDY; DNA POLYMORPHISM; ELBOW FLEXION; FEMALE; GENOTYPE; HUMAN; HUMAN EXPERIMENT; MALE; MUSCLE ISOMETRIC CONTRACTION; MUSCLE STRENGTH; MUSCLE TRAINING; NORMAL HUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL;

ADULT; CILIARY NEUROTROPHIC FACTOR; FEMALE; GENE FREQUENCY; HOMOZYGOTE; HUMANS; IRELAND; ISOMETRIC CONTRACTION; MAGNETIC RESONANCE IMAGING; MALE; MUSCLE STRENGTH; MUSCLE, SKELETAL; PHENOTYPE; POLYMORPHISM, SINGLE NUCLEOTIDE; RESISTANCE TRAINING; SEX FACTORS; UNITED STATES; UPPER EXTREMITY; YOUNG ADULT;

EID: 70350120744     PISSN: 87507587     EISSN: 15221601     Source Type: Journal    
DOI: 10.1152/japplphysiol.90835.2008     Document Type: Article

References (23)

1. Arking DE, Fallin DM, Fried LP, Li T, Beamer BA, Xue QL, Chakravarti A, Walston J. Variation in the ciliary neurotrophic factor gene and muscle strength in older Caucasian women. J Am Geriatr Soc 54: 823-826, 2006. (Pubitemid 44030206)
2. Bray MS, Hagberg JM, Pérusse L, Rankinen T, Roth SM, Wolfarth B, Bouchard C. The human gene map for performance and health-related fitness phenotypes: the 2006-2007 update. Med Sci Sports Exerc 41: 35-73, 2009.
3. Clarkson PM, Devaney JM, Gordish-Dressman H, Thompson PD, Hubal MJ, Urso M, Price TB, Angelopoulos TJ, Gordon PM, Moyna NM, Pescatello LS, Visich PS, Zoeller RF, Seip RL, Hoffman EP. ACTN3 genotype is associated with increases in muscle strength in response to resistance training in women. J Appl Physiol 99: 154-163, 2005. (Pubitemid 40934477)
4. De Mars G, Windelinckx A, Beunen G, Delecluse C, Lefevre J, Thomis MA. Polymorphisms in the CNTF and CNTF receptor genes are associated with muscle strength in men and women. J Appl Physiol 102: 1824-1831, 2007.
5. Delmonico MJ, Kostek MC, Doldo NA, Hand BD, Walsh S, Conway JM, Carignan CR, Roth SM, Hurley BF. α-Actinin-3 (ACTN3) R577X polymorphism influences knee extensor peak power response to strength training in older men and women. J Gerontol A Biol Sci Med Sci 62: 206-212, 2007. (Pubitemid 47065746)
6. Forger NG, Roberts SL, Wong V, Breedlove SM. Ciliary neurotrophic factor maintains motoneurons and their target muscles in developing rats. J Neurosci 13: 4720-4726, 1993. (Pubitemid 23326342)
7. Guillet C, Auguste P, Mayo W, Kreher P, Gascan H. Ciliary neurotrophic factor is a regulator of muscular strength in aging. J Neurosci 19: 1257-1262, 1999. (Pubitemid 29088908)
8. Hand BD, Kostek MC, Ferrell RE, Delmonico MJ, Douglass LW, Roth SM, Hagberg JM, Hurley BF. Influence of promoter region variants of insulin-like growth factor pathway genes on the strength-training response of muscle phenotypes in older adults. J Appl Physiol 103: 1678-1687, 2007.
9. Hubal MJ, Gordish-Dressman H, Thompson PD, Price TB, Hoffman EP, Angelopoulos TJ, Gordon PM, Moyna NM, Pescatello LS, Visich PS, Zoeller RF, Seip RL, Clarkson PM. Variability in muscle size and strength gain after unilateral resistance training. Med Sci Sports Exerc 37: 964-972, 2005. (Pubitemid 40847458)
10. Ip NY, McClain J, Barrezueta NX, Aldrich TH, Pan L, Li Y, Wiegand SJ, Friedman B, Davis S, Yancopoulos GD. The α-component of the CNTF receptor is required for signaling and defines potential CNTF targets in the adult and during development. Neuron 10: 89-102, 1993. (Pubitemid 23045429)
11. Kostek MC, Delmonico MJ, Reichel JB, Roth SM, Douglass L, Ferrell RE, Hurley BF. Muscle strength response to strength training is influenced by insulin-like growth factor 1 genotype in older adults. J Appl Physiol 98: 2147-2154, 2005. (Pubitemid 40726909)
12. Lee M, Carroll TJ. Cross education: possible mechanisms for the contralateral effects of unilateral resistance training. Sports Med 37: 1-14, 2007. (Pubitemid 46066256)
13. Munn J, Herbert RD, Gandevia SC. Contralateral effects of unilateral resistance training: a meta-analysis. J Appl Physiol 96: 1861-1866, 2004.
14. Pescatello LS, Kostek MA, Gordish-Dressman H, Thompson PD, Seip RL, Price TB, Angelopoulos TJ, Clarkson PM, Gordon PM, Moyna NM, Visich PS, Zoeller RF, Devaney JM, Hoffman EP. ACE ID genotype and the muscle strength and size response to unilateral resistance training. Med Sci Sports Exerc 38: 1074-1081, 2006. (Pubitemid 43902489)
15. Roth SM. Perspective on the future use of genomics in exercise prescription. J Appl Physiol 104: 1243-1245, 2008.
16. Roth SM, Ferrell RF, Hurley BF. Strength training for the prevention and treatment of sarcopenia. J Nutr Health Aging 4: 143-155, 2000.
17. Roth SM, Metter EJ, Lee MR, Hurley BF, Ferrell RE. C174T polymorphism in the CNTF receptor gene is associated with fat-free mass in men and women. J Appl Physiol 95: 1425-1430, 2003.
18. Roth SM, Schrager MA, Ferrell RE, Riechman SE, Metter EJ, Lynch NA, Lindle RS, Hurley BF. CNTF genotype is associated with muscular strength and quality in humans across the adult age span. J Appl Physiol 90: 1205-1210, 2001.
19. Roth SM, Schrager MA, Lee MR, Metter EJ, Hurley BF, Ferrell RE. Interleukin-6 (IL6) genotype is associated with fat-free mass in men but not women. J Gerontol A Biol Sci Med Sci 58: B1085-B1088, 2003.
20. Sendtner M, Carroll P, Holtmann B, Hughes RA, Thoenen H. Ciliary neurotrophic factor. J Neurobiol 25: 1436-1453, 1994.
21. Takahashi R, Yokoji H, Misawa H, Hayashi M, Hu J, Deguchi T. A null mutation in the human CNTF gene is not causally related to neurological diseases. Nat Genet 7: 79-84, 1994. (Pubitemid 24232385)
22. Uthurralt J, Gordish-Dressman H, Bradbury M, Tesi-Rocha C, Devaney J, Harmon B, Reeves EK, Brandoli C, Hansen BC, Seip RL, Thompson PD, Price TB, Angelopoulos TJ, Clarkson PM, Moyna NM, Pescatello LS, Visich PS, Zoeller RF, Gordon PM, Hoffman EP. PPARα L162V underlies variation in serum triglycerides and subcutaneous fat volume in young males. BMC Med Genet 8: 55, 2007. (Pubitemid 350011241)
23. van Rossum EF, Voorhoeve PG, te Velde SJ, Koper JW, Delemarrevan de Waal HA, Kemper HC, Lamberts SW. The ER22/23EK polymorphism in the glucocorticoid receptor gene is associated with a bene-ficial body composition and muscle strength in young adults. J Clin Endocrinol Metab 89: 4004-4009, 2004.