Interferon-γ release assays for the diagnosis of Mycobacterium tuberculosis infection in children: A literature review

International Journal of Immunopathology and Pharmacology

Volumn 25, Issue 2, 2012, Pages 335-343

  Chiappini, E ^a   Bonsignori, F ^a   Accetta, G ^b   Boddi, V ^a   Galli, L ^a   Biggeri, A ^a,b   De Martino, Maurizio ^a  

^a UNIVERSITY OF FLORENCE   (Italy)

^b CANCER RESEARCH AND PREVENTION INSTITUTE ISPO   (Italy)

Author keywords

Children; IGRA; Meta analysis; Tuberculosis

Indexed keywords

CULTURE FILTRATE PROTEIN 10; EARLY SECRETORY ANTIGENIC TARGET 6; GAMMA INTERFERON; ANTIGEN; CFP I0 ANTIGEN; UNCLASSIFIED DRUG;

ASSAY; CHECKLIST; COCHRANE LIBRARY; CYTOKINE RELEASE; EMBASE; ENZYME LINKED IMMUNOSPOT ASSAY; GOLD STANDARD; HUMAN; IMMUNOCOMPROMISED PATIENT; KAPPA STATISTICS; MEDICAL LITERATURE; MEDLINE; MYCOBACTERIUM TUBERCULOSIS; PRIORITY JOURNAL; REVIEW; SENSITIVITY ANALYSIS; TUBERCULIN TEST; TUBERCULOSIS; AUSTRALIAN; BCG VACCINATION; CORRELATION ANALYSIS; GERMANY; IMMUNE RESPONSE; IMMUNOCOMPROMIZED PATIENT; INTERFERON GAMMA RELEASE ASSAY; META ANALYSIS; MYCOBACTERIUM TUBERCULOSIS TEST KIT; PEDIATRICS; SENSITIVITY AND SPECIFICITY; SERODIAGNOSIS; SOUTH AFRICAN; STATISTICAL ANALYSIS; SYSTEMATIC REVIEW; UNITED KINGDOM; UNITED STATES;

EID: 84863677835     PISSN: 03946320     EISSN: None     Source Type: Journal    
DOI: 10.1177/039463201202500203     Document Type: Review

References (45)

1. Kampmann B, Whittaker E, Williams A, et al. Interferon-γ release assay do not identify more children with active tuberculosis than the tuberculin skin test. Eur Rcspir J 2009; 33:1374-82.
2. Detjen AK, Keil T, Roll S, et al. Interferon-γ release assay improve the diagnosis of tuberculosis and nontuberculous mycobacterial disease in children in a country with a low incidence of tuberculosis. Clin Infect Dis 2007; 45:322-8. (Pubitemid 47101028)
3. Dogra S, Narang P, Mendiratta DK, et al. Comparison of a whole blood interferon-γ assay with tuberculin skin testing for the detection of tuberculosis infection in hospitalize children in rural India. J Infect 2007; 54:267-76. (Pubitemid 46238165)
4. Dominguez J, Ruiz-Manzano J, de Souza-Galvao M, et al. Comparison of two commercially available gamma interferon blood tests for immunodiagnosis of tuberculosis. Clin Vaccine Immunol 2008; 15:168-71. (Pubitemid 351966546)
5. Herrmann JL, Belloy M, Porcher R, et al. Temporal dynamics of interferon gamma responses in children evaluated for tuberculosis. PLoS ONE 2009; 4:e4130.
6. Jacobs S, Warman A, Richardson R, et al. The tuberculin skin test is unreliable in school children BCG-vaccinated in infancy and at low risk of tuberculosis infection. Pediatr Infect Dis J 2011; 30:754-8.
7. Dayal R, Verma V, Sharma B, Kumar G, Kumar N, Gupta R, Katoch VM, Joshi B, Chauhan DS. Diagnostic value of Interferon- gamma release assays (QuantiFERON-TB Gold® In Tube) in childhood tuberculosis. Indian J Pediatr 2011. [Epub ahead of print]
8. Connell TG, Ritz N, Paxton GA, et al. A three-way comparison of tuberculin skin testing, quantiFERON-TB Gold and T-SPOTTB in children. PLoS ONE 2008; 3:e2624.
9. Nicol MP, Davies MA, Wood K, et al. Comparison of T-SPOT.TB assay and tuberculosis skin tests for the evaluation of young children at high risk for tuberculosis in a community setting. Paediatrics 2009; 123:38-43.
10. Bamford AR, Crook AM, Clark JE, et al. Comparison of interferon-gamma release assays and tuberculin skin test in predicting active tuberculosis (TB) in children in the UK: a paediatric TB network study. Arch Dis Child 2010; 95:180-86.
11. Lighter J, Rigaud M, Eduardo R et al. Latent tuberculosis diagnosis in children by using the QuantiFERON-TB Gold in-Tube test. Paediatrics 2009; 123:30-37.
12. Warier A, Gunawathi S, Enkatesh V, et al. T-cell assay as a diagnosis tool for tuberculosis. Indian Paediatrics 2009; 47:90-92.
13. Altet-Gómez N, De Souza-Galvao M, Latorre I, et al. Diagnosing TB infection in children: analysis of discordances using in vitro tests and the tuberculin skin test. Eur Respir J 2011; 37:1166-74.
14. Grare M, Derelle J, Dailloux M, et al. QuantiFERON-TB Gold In-Tube as help for the diagnosis of tuberculosis in a French paediatric hospital. Diagn Microbiol Infect Dis 2011; 66:366-72.
15. Cruz AT, Geltemeyer AM, Starke JR, Flores JA, Graviss EA, Smith KC. Comparing the tuberculin skin test and T-SPOT.TB blood test in children. Pediatrics 2011; 127:e31-8. Epub 2010.
16. Tsolia MN, Mavrikou M, Critselis E, et al. Whole blood interferon-γ release assay is a useful tool fort eh diagnosis of tuberculosis infection particularly among Bacille Calmette Guerin-vaccinated children. Paediatr Infect Dis J 2010; 29:1137-40.
17. Okada K, Mao TE, Mori T, et al. Performance of an interferon-gamma release assay for diagnosing latent tuberculosis infection in children. Epidemiol Infect 2008; 136:1179-87
18. Debord C, De Lauzanne A, Gourgouillon N, Guérin-El Khourouj V, Pédron B, Gaudelus J, Faye A, Sterkers G. Interferon-gamma release assay performance for diagnosing tuberculosis disease in 0- to 5-year-old children. Pediatr Infect Dis J 2011; 30:995-7.
19. Moyo S, Isaacs F, Gelderbloem S, et al. Tuberculin skin test and QuantiFERON® assay in young children investigated for tuberculosis in South Africa. Int J Tuberc Lung Dis 2011; 15:1176-81, i.
20. Pavić I, Topić RZ, Raos M, Aberle N, Dodig S. Interferon-γ release assay for the diagnosis of latent tuberculosis in children younger than 5 years of age. Pediatr Infect Dis J 2011; 30:866-70.
21. Liebeschuetz S, Bamber S, Deeks J et al. Diagnosis of tuberculosis in South African children with a T-cell-based assay: a prospective cohort study. Lancet 2004; 364:2196-203. (Pubitemid 40018449)
22. Haustein T, Ridout D, Hartley JC, et al. The likelihood of an indeterminate test result from a whole-blood interferon-γ release assay for the diagnosis of Mycobacterium tuberculosis infection in children correlates with age and immune status. Paediatr Infect Dis J 2009; 28:669-73.
23. Bruzzese E, Bocchino M, Assante LR et al. Gamma interferon release assays for detection of tuberculosis infection in immune-compromised children in a country in which the prevalence of tuberculosis is low. J Clin Microbiol 2009; 47:2355-7.
24. Stefan DC, Dippenaar A, Detjen AK, et al. Interferon-gamma relese assay for the detection of Mycobacterium tuberculosis infection in children with cancer. Int J Tuberc Lung Dis 2010; 14:689-94.
25. Davies MA, Connell T, Johannisen C, et al. Detection of tuberculosis in HIV-infected children using an enzyme-linked immunospot assay. AIDS 2009; 23:961-9.
26. Mandalakas AM, Hesseling AC, Chegou NN, et al. High level of discordant IGRA results in HIV-infected adults and children. Int J Tuberc Lung Dis 2008; 12:417-23. (Pubitemid 351507255)
27. Connell TG, Davies MA, Johannisen C, et al. Reversion and conversion of Mycobacterium tuberculosis IFN-gamma ELISpot results during anti-tuberculous treatment in HIV-infected children. BMC Infect Dis 2010; 10:138.
28. Bianchi L, Galli L, Moriondo M, et al. Interferon-γ release assay improves the diagnosis of tuberculosis in children. Ped Infect Dis J 2009; 28:510-4.
29. Bergamini BM, Losi M, Vaienti F, et al. Performance of commercial blood tests for the diagnosis of latent tuberculosis infection in children and adolescents. Paediatrics 2009; 123:e419-24.
30. Connell TG, Tebruegge M, Ritz N, et al. The potential danger of a solely interferon-{gamma} release assay-based approach to testing for latent Mycobacterium tuberculosis infection in children. Thorax 2011; 66:263-4.
31. Brock I, Weldingh K, Lillebaek T, Follmann F, Andersen P. Comparison of tuberculin skin test and new specific blood test in tuberculosis contacts. Am J Respir Crit Care Med 2004; 170:65-9. (Pubitemid 38997753)
32. Ewer K, Deeks J, Alvarez L, et al. Comparison of T-cell-based assay with tuberculin skin test for diagnosis of Mycobacterium tuberculosis infection in a school tuberculosis outbreak. Lancet 2003; 361:1168-73. (Pubitemid 36398385)
33. Higuchi K, Kondo S, Wada M, et al. Contact investigation in a primary school using a whole blood interferon-gamma assay. J Infect 2009; 58:352-7.
34. Soysal A, Millington KA, Bakir M, et al. Effect of BCG vaccination on risk of Mycobacterium tuberculosis infection in children with household tuberculosis contact: a prospective community-based study. Lancet 2005; 366:1443-51. (Pubitemid 41483810)
35. Diel R, Loddenkemper R, Niemann S, et al. Negative and positive predictive value of a whole-blood IGRA for developing active TB - An update. Am J Respir Crit Care Med 2011; 183:88-95.
36. Richeldi L, Ewer K, Losi M, et al. T-cell-based tracking of multidrug resistant tuberculosis infection after brief exposure. Am J Respir Crit Care Med 2004; 170:288-95. (Pubitemid 38971414)
37. Adetifa IM, Ota MO, Jeffries DJ, et al. Commercial interferon gamma release assays compared to the tuberculin skin test for diagnosis of latent Mycobacterium tuberculosis infection in childhood contacts in the Gambia. Paediatr Infect Dis J 2010; 29:439-43.
38. Bakir M, Millington KA, Soysal A, et al. Prognostic value of T-cell-based, interferon-γ biomarker in children with tuberculosis contact. Ann Intern Med 2008; 149:777-86.
39. Mahomed H, Hawkridge T, Verver S, et al. The tuberculin skin test versus QuantiFERON TB Gold® in predicting tuberculosis disease in an adolescent cohort study in South Africa. PLoS One 2011; 6:e17984.
40. Nenadić N, Kirin BK, Letoja IZ, Plavec D, Topić RZ, Dodig S. Serial interferon-γ Release assay in children with latent tuberculosis infection and children with tuberculosis. Pediatr Pulmonol 2011; doi: 10.1002/ppul.21555. [Epub ahead of print]
41. Lewinsohn DA, Lobato MN, Jereb JA. Interferon-gamma release assays: new diagnostic tests for Mycobacterium tuberculosis infection, and their use in children. Curr Opin Paediatr 2010; 22:71-6.
42. Connel TG, Tebruegge M, Ritz N, et al. Indeterminate interferon-gamma release assay results in children. Paediatr Infect Dis J 2010; 29:285-6.
43. Thomas TA, Mondai D, Noor Z, et al. Malnutrition and helminth infection affect performance of an interferon {gamma}-release assay. Paediatrics 2010; 126:e1522-9.
44. Lucas M, Nicol P, McKinnon E, et al. A prospective large-scale study of methods for the detection of latent Mycobacterium tuberculosis infection in refugee children. Thorax 2010; 65:442-8.
45. Diel R, Loddenkemper R, Nienhaus A. Evidence based comparison of commercial interferon-gamma release assays for detecting active tuberculosis - a meta-analysis. Chest 2010; 137:952-68.