Evaluation of certain food additives and contaminants

World Health Organization - Technical Report Series

Volumn , Issue 960, 2010, Pages 1-226

[No Author Info available]

Author keywords

[No Author keywords available]

Indexed keywords

1,2 DICARBONYL DERIVATIVE; ACETAL DERIVATIVE; ACTIVATED CARBON; ALCOHOL DERIVATIVE; ALDEHYDE; ALICYCLIC COMPOUND; ALIPHATIC COMPOUND; AROMATIC AMIDE; AROMATIC AMINE; BENZYL DERIVATIVE; CADMIUM; CARBOXYLIC ACID; CASSIA EXTRACT; CROTONIC ACID DERIVATIVE; ESTER; FATTY ACID ESTER; FLAVORING AGENT; FOOD ADDITIVE; FOOD DYE; GLYCOSIDE; KETOL; KETONE; LACTONE; LEAD; PHENOL DERIVATIVE; SUCROSE ESTER DERIVATIVE; SULFIDE; TERPENOID DERIVATIVE; THIOL DERIVATIVE; TITANIUM DIOXIDE;

AGRICULTURE; ALCOHOLIC BEVERAGE; BLOOD SAMPLING; CACAO; CHEMICAL STRUCTURE; COFFEE; DAIRY PRODUCT; DIET; EGG; FISH; FOOD COLOR; FOOD CONTAMINATION; FOOD INTAKE; FOOD POISONING; FRUIT; FRUIT JUICE; GENOTOXICITY; GRAIN; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HONEY; HUMAN; HYDROLYSIS; ISOMER; LD 50; LEGUME; MEAT; MOLLUSC; NONHUMAN; NUT; OAT; POULTRY; REVIEW; RICE; RISK ASSESSMENT; SHELLFISH; SWEET CHERRY; TEA; UNITED NATIONS; VEGETABLE; WATER CONTAMINATION; WHEAT; WORLD HEALTH ORGANIZATION;

EID: 84863673841     PISSN: 05123054     EISSN: None     Source Type: Book Series    
DOI: None     Document Type: Review

References (33)

1. FAO/WHO. Joint FAO/WHO Conference on Food Additives. Rome, Italy, Food and Agriculture Organization of the United Nations, 1956 (FAO Nutrition Meetings Report Series, No. 11); Geneva, Switzerland, World Health Organization, 1956 (WHO Technical Report Series, No. 107).
2. FAO/WHO. International Numbering System for Food Additives (list in numerical order and list in alphabetical order). In: Codex class names and the International Numbering System for Food Additives. Rome, Italy, Food and Agriculture Organization of the United Nations, Joint FAO/WHO Food Standards Programme, Codex Alimentarius Commission, pp. 4-56. Adopted in 1989, revised in 2008, last amended in 2010 (CAC/GL 36-1989; http://www.codexalimentarius.net/ download/standards/7/CXG-036e.pdf).
3. FAO/WHO. Codex General Standard for Food Additives. Rome, Italy, Food and Agriculture Organization of the United Nations, Joint FAO/WHO Food Standards Programme, Codex Alimentarius Commission (http://www.codexalimentarius.net/ gsfaonline/index.html).
4. FAO/WHO. Guidelines on substances used as processing aids. Rome, Italy, Food and Agriculture Organization of the United Nations, Joint FAO/WHO Food Standards Programme, Codex Alimentarius Commission, 2010 (CAC/GL 75-2010; http://www.codexalimentarius.net/download/standards/11537/CXG-075e.pdf).
5. FAO/WHO. Principles and methods for the risk assessment of chemicals in food. Geneva, World Health Organization, 2009 (Environmental Health Criteria, No. 240; http://whqlibdoc.who.int/ehc/).
6. Til HP et al. Evaluation of the oral toxicity of acetaldehyde and formaldehyde in a 4-week drinking water study in rats. Food and Chemical Toxicology, 1988, 26:447-452.
7. Cramer GM, Ford RA, Hall RL. Estimation of toxic hazard - a decision tree approach. Food and Cosmetics Toxicology, 1978, 16:255-276. (Pubitemid 9010193)
8. Nijssen LM, van Ingen-Visscher CA, Donders JJM, eds. VCF (Volatile Compounds in Food) database. Version 11.1.1. Zeist, Netherlands, TNO Quality of Life, 2009 (http://www.vcf-online.nl/VcfHome.cfm).
9. European Flavour and Fragrance Association. EFFA poundage survey 2004: European inquiry on volume of use. Unpublished report, 2004. Submitted to WHO by the International Organization of the Flavor Industry, Brussels, Belgium.
10. Japan Flavor and Fragrance Materials Association. JFFMA poundage survey 2005: Japanese inquiry on volume use. Unpublished report, 2005. Submitted to WHO by the International Organization of the Flavor Industry, Brussels, Belgium.
11. Gavin CL, Williams MC, Hallagan JB. 2005 poundage and technical effects update survey. Washington, DC, USA, Flavor and Extract Manufacturers Association, 2008.
12. International Organization of the Flavor Industry. Interim inquiry on volume use and added use levels for flavouring agents to be presented at the JECFA 73rd meeting. Submitted to WHO by the International Organization of the Flavor Industry, Brussels, Belgium, 2009.
13. Cox GE, Bailey DE, Hall RL. 90-day feeding study in rats with 5-hydroxy-2,4-decadienoic acid-lactone. Unpublished report to the Research Institute for Fragrance Materials, Woodcliff, NJ, USA, 1974. Submitted to WHO by the International Organization of the Flavor Industry, Brussels, Belgium.
14. Shellenberger T. Subacute toxicity evaluation of α-angelica lactone with rats. Unpublished report from Gulf South Research Institute, New Iberia, LA, USA, 1971. Private communication to the Flavor and Extract Manufacturers Association, Washington, DC, USA. Submitted to WHO by the International Organization of the Flavor Industry, Brussels, Belgium.
15. Billecke S et al. Human serum paraoxonase (PON1) isozymes Q and R hydrolyze lactones and cyclic carbonate esters. Drug Metabolism and Disposition, 2000, 28(11):1335-1342.
16. Moreno OM. Unpublished report to the Research Institute of Fragrance Materials, Woodcliff, NJ, USA, 1979. Submitted to WHO by the International Organization of the Flavor Industry, Brussels, Belgium.
17. Uhde H. Mutagenicity study of 5,6-dimethyl-tetrahydro-pyran-2-one in the Salmonella typhimurium (in vitro). Unpublished report, LPT Laboratory of Pharmacology, Hamburg, Germany, 2004. Private report to the Research Institute for Fragrance Materials, Woodcliff, NJ, USA. Submitted to WHO by the International Organization of the Flavor Industry, Brussels, Belgium.
18. Poth A. Salmonella typhimurium reverse mutations assay with isoambrettolide. Study No. 45408, Cryotest Cell Research GMBH, Rossdorf, Germany, 2003. Private report to the Research Institute for Fragrance Materials, Woodcliff Lake, NJ, USA. Submitted to WHO by the International Organization of the Flavor Industry, Brussels, Belgium.
19. Jones E, Gant R. Gamma jasmolactone: bacterial mutation assay. Unpublished report, 1990. Private communication to the Flavor and Extract Manufacturers Association, Washington, DC, USA. Submitted to WHO by the International Organization of the Flavor Industry, Brussels, Belgium.
20. Stofberg J, Grundschober F. Consumption ratio and food predominance of flavoring materials. Perfumer and Flavorist, 1989, 12:27.
21. Nelson DL, Cox MM. Lehninger principles of biochemistry, 5th ed. New York, NY, USA, Worth Publishers, Inc., 2008:567-592.
22. Moreno OM. Acute oral toxicity in rats (ethyl acetoacetate ethyleneglycol ketal). MB Research Laboratories Inc., Spinnerstown, PA, USA, 1978. Unpublished report to the Research Institute for Fragrance Materials, Woodcliff Lake, NJ, USA. Submitted to WHO by the International Organization of the Flavor Industry, Brussels, Belgium.
23. Moreno OM. Acute oral toxicity in rats (diisobutyl adipate, ethyl acetoacetate ethyleneglycol ketal). MB Research Laboratories Inc., Spinnerstown, PA, USA, 1980. Unpublished report to the Research Institute for Fragrance Materials, Woodcliff Lake, NJ, USA. Submitted to WHO by the International Organization of the Flavor Industry, Brussels, Belgium.
24. Sokolowski A. Salmonella typhimurium reverse mutation assay with fructone. RCC-CCR Study No. 838606, RCC Cytotest Cell Research GmbH (RCC-CCR), Rossdorf, Germany, 2004. Unpublished report to the Flavor and Extract Manufacturers Association, Washington, DC, USA. Submitted to WHO by the International Organization of the Flavor Industry, Brussels, Belgium.
25. Felice B. Acute oral toxicity test up-and-down procedure - OECD. Test substance: (R)-(-)-1-octen-3-ol. Unpublished report No. 05-3256-G1 from Toxicon Corporation, Bedford, MA, USA, 2005. Submitted to WHO by the International Organization of the Flavor Industry, Brussels, Belgium.
26. Felice B. Acute oral toxicity test up-and-down procedure - OECD. Test substance: 1-octen-3-ol. Unpublished report No. 05-1595-G1 from Toxicon Corporation, Bedford, MA, USA, 2005. Submitted to WHO by the International Organization of the Flavor Industry, Brussels, Belgium.
27. Engelhardt G. Report on the study of octenol in the Ames Salmonella/mammalian microsome mutagenicity test and reverse mutation assay - E. coli WP2 uvrA (standard plate test and preincubation test). Unpublished report No. 40M0479/884145 from BASF Aktiengesellschaft, Ludwigshafen/Rhein, Germany, 1988. Submitted to WHO by the International Organization of the Flavor Industry, Brussels, Belgium.
28. Kreja L, Seidel HJ. Evaluation of the genotoxic potential of some microbial volatile organic compounds (MVOC) with the comet assay, the micronucleus assay and the HPRT gene mutation assay. Mutation Research, 2002, 513:143-150. (Pubitemid 33096333)
29. Amzal B et al. Population toxicokinetic modeling of cadmium for health risk assessment. Environmental Health Perspectives, 2009, 117:1293-1301.
30. FAO/WHO. General guidelines on sampling. Rome, Italy, Food and Agriculture Organization of the United Nations, Joint FAO/WHO Food Standards Programme, Codex Alimentarius Commission, 2004, 69 pp. (CAC/GL 50-2004; http://www.codexalimentarius.net/download/standards/10141/CXG-050e.pdf).
31. FAO/WHO. Policy of the Codex Committee on Contaminants in Foods for exposure assessment of contaminants and toxins in foods or food groups. In: Codex Alimentarius Commission procedural manual, 19th ed. Rome, Food and Agriculture Organization of the United Nations, Joint FAO/WHO Food Standards Programme, Codex Alimentarius Commission, 2010.
32. European Food Safety Authority. Cadmium in food: Scientific opinion of the panel on contaminants in the food chain. EFSA Journal, 2009, 980:1-139.
33. Lanphear BP et al. Low-level environmental lead exposure and children's intellectual function: an international pooled analysis. Environmental Health Perspectives, 2005, 113:894-899. (Pubitemid 40984191)