Geographic atrophy

Age-Related Macular Degeneration, Second Edition

Volumn , Issue , 2007, Pages 111-124

  Solomon, Sharon D ^a   Sunness, Janet S ^b  

^a JOHNS HOPKINS UNIVERSITY   (United States)

^b GREATER BALTIMORE MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 84863658583     PISSN: None     EISSN: None     Source Type: Book    
DOI: None     Document Type: Chapter

References (71)

1. Sunness JS, Schuchard R, Shen N, Rubin GS, Dagnelie G, Haselwood DM. Landmark-driven fundus perimetry using the scanning laser ophthalmoscope (SLO). Invest Ophthalmol Vis Sci 1995; 36:1863-74.
2. Sarks JP, Sarks SH, Killingsworth MC. Evolution of geographic atrophy of the retinal pigment epithelium. Eye 1988; 2:552-77.
3. Maguire P, Vine AP. Geographic atrophy of the retinal pigment epithelium. Am J Ophthalmol 1986; 102:621-5.
4. Schatz H, McDonald HR. Atrophic macular degeneration: rate of spread of geographic atrophy and visual loss. Ophthalmology 1989; 96:1541-51.
5. Sunness JS, Rubin GS, Applegate CA, et al. Visual function abnormalities and prognosis in eyes with age-related geographic atrophy of the macula and good acuity. Ophthalmology 1997; 104:1677-91.
6. Ferris FL, III, Fine SL, Hyman L. Age-related macular degeneration and blindness due to neovascular maculopathy. Arch Ophthalmol 1984; 102:1640-2.
7. Sunness JS, Gonzalez-Baron J, Applegate CA, et al. Enlargement of atrophy and visual acuity loss in the geographic atrophy form of age-related macular degeneration. Ophthalmology 1999; 106:1768-79.
8. Klein R, Klein BEK, Franke T. The relationship of cardiovascular disease and its risk factors to age-related maculopathy: the Beaver Dam Eye Study. Ophthalmology 1993; 100:406-14.
9. Vingerling JR, Dielemans I, Hofman A, et al. The prevalence of age-related maculopathy in the Rotterdam Study. Ophthalmology 1995; 102:205-10.
10. Quillen D, Blankenship G, Gardner T. Aged eyes: ocular findings in individuals 90 years of age and older. Invest Ophthalmol Vis Sci 1996; 47:S111.
11. Sunness JS, Gonzalez-Baron J, Bressler NM, Hawkins B, Applegate CA. The development of choroidal neovascularization in eyes with the geographic atrophy form of age-related macular degeneration. Ophthalmology 1999; 106:910-9.
12. Nasrallah F, Jalkh AE, Trempe CL, McMeel JW, Schepens CL. Subretinal hemorrhage in atrophic agerelated macular degeneration. Am J Ophthalmol 1988; 107:38-41.
13. Sunness JS, Bressler NM, Maguire MG. Scanning laser ophthalmoscopic analysis of the pattern of visual loss in age-related geographic atrophy of the macula. Am J Ophthalmol 1995; 119:143-51.
14. Sunness JS, Bressler NM, Tian Y, Alexander J, Applegate CA. Measuring geographic atrophy in advanced age-related macular degeneration. Invest Ophthalmol Vis Sci 1999; 40:1761-9.
15. Green WR, Key SN, III. Senile macular degeneration: a histopathologic study. Trans Am Ophthalmol Soc 1977; 75:180-254.
16. Korte GE, Reppucci V, Henkind P. Retinal pigment epithelium destruction causes choriocapillary atrophy. Invest Ophthalmol Vis Sci 1984; 25:1135-45.
17. Leonard DS, Zhang XG, Panozzo G, Sugino IK, Zarbin MA. Clinicopathologic correlation of localized retinal pigment epithelial debridement. Invest Ophthalmol Vis Sci 1997; 38:1094-109.
18. Green WR, Enger C. Age-related macular degeneration histopathologic studies: the 1992 Lorenz E. Zimmerman lecture. Ophthalmology 1993; 100:1519-35.
19. Sarks SH. Changes in the region of the choriocapillaris in ageing and degeneration. XXIII Concilium Ophthalmologicum, Kyoto. Amsterdam-Oxford: Excerpta Medica, 1979.
20. Elman MJ, Fine SL, Murphy RP, Patz A, Auer C. The natural history of serous retinal pigment epithelium detachment in patients with age-related macular degeneration. Ophthalmology 1986; 93:224-30.
21. Friedman E, Krupsky S, Lane AM, et al. Ocular blood flow velocity in age-related macular degeneration. Ophthalmology 1995; 102:640-6.
22. Grunwald JE, Hariprasad SM, DuPont J, et al. Foveolar choroidal blood flow in age-related macular degeneration. Invest Ophthalmol Vis Sci 1998; 39:385-90.
23. Hirvela H, Luukinen H, Laara E, Sc L, Laatikainen L. Risk factors of age-related maculopathy in a population 70 years of age or older. Ophthalmology 1996; 103:871-7.
24. Friedman DS, Katz J, Bressler NM, Rahmani B, Tielsch JM. Racial differences in the prevalence of age-related macular degeneration: the Baltimore Eye Survey. Ophthalmology 1999; 106:1049-55.
25. Klein R, Klein BE, Jensen SC, Meuer SM. The five-year incidence and progression of age-related maculopathy: the Beaver Dam Eye Study. Ophthalmology 1997; 104:7-21.
26. Porter JW, Thallemer JM. Geographic atrophy of the retinal pigment epithelium: diagnosis and vision rehabilitation. J Am Opt Assoc 1981; 52:503-8.
27. Ritter LL, Klein R, Klein BE, Mares-Perlman JA, Jensen SC. Alcohol use and age-related maculopathy in the Beaver Dam Eye Study. Am J Ophthalmol 1995; 120:190-6.
28. Smith W, Mitchell P, Leeder SR. Smoking and age-related maculopathy: the Blue Mountain Eye Study. Arch Ophthalmol 1996; 114:1518-23.
29. Age-Related Eye Disease Study Research Group. Risk factors associated with age-related macular degeneration: a case-control study in the Age-Related Eye Disease Study: AREDS report No. 3. Ophthalmology 2000; 107:2224-32.
30. Piguet B, Heon E, Munier FL, et al. Full characterization of the maculopathy associated with an Arg-12-Trp mutation in the RDS/peripherin gene. Ophthalmic Genet 1996; 17:175-86.
31. Allikmets R, Shroyer NF, Singh N, et al. Mutation of the Stargardt disease gene (ABCR) in age-related macular degeneration. Science 1997; 277:1805-7.
32. Pennisi E. Human genetics: gene found for the fading eyesight of old age. Science 1997; 277:1765-6.
33. Allikmets and International ABCR screening Consortium. Further evidence for an association of the ABCR alleles with age-related macular degeneration. Am J Hum Genet 2000; 67:487-91.
34. Yates JR, Moore AT. Genetic susceptibility to age-related macular degeneration. J Med Genet 2000; 37(2):83-7.
35. Sepp T, Khan JC, Thurlby DA, et al. Complement factor H variant Y402H is a major risk determinant for geographic atrophy and choroidal neovascularization in smokers and nonsmokers. Invest Ophthalmol Vis Sci 2006; 47:536-40.
36. Gass JDM. Drusen and disciform macular detachment and degeneration. Arch Ophthalmol 1973; 90:206-17.
37. Peli E, Lahav M. Drusen measurements from fundus photographs using computer image analysis. Ophthalmology 1986; 93:1575-80.
38. Braunstein RA, Gass JDM. Serous detachments of the retinal pigment epithelium in patients with senile macular disease. Am J Ophthalmol 1979; 88:652-60.
39. Casswell AG, Kohen D, Bird AC. Retinal pigment epithelial detachments in the elderly: classification and outcome. Br J Ophthalmol 1985; 69:397-403.
40. Meredith TA, Braley RE, Aaberg TM. Natural history of serous detachments of the retinal pigment epithelium. Am J Ophthalmol 1979; 88:643-51.
41. Sunness JS, Applegate CA, Haselwood D, Rubin GS. Fixation patterns and reading rates in eyes with central scotomas from advanced atrophic age-related macular degeneration and Stargardt disease. Ophthalmology 1996; 103:1458-66.
42. Sunness JS, Bressler NM, Applegate CA. Ophthalmoscopic features associated with geographic atrophy from agerelated macular degeneration. Invest Ophthalmol Vis Sci 1999; 40:S314 (Abstract).
43. Steinmetz RL, Walter D, Fitzke FW, Bird AC. Prolonged dark adaptation in patients with age-related macular degeneration. Invest Ophthalmol Vis Sci 1991; 32:S711.
44. Steinmetz RL, Haimovici R, Jubb C, Fitzke FW, Bird AC. Symptomatic abnormalities of dark adaptation in patients with age-related Bruch’s membrane change. Br J Ophthalmol 1993; 77:549-54.
45. Sunness JS, Massof RW, Johnson MA, Bressler NM, Bressler SB, Fine SL. Diminished foveal sensitivity may predict the development of advanced age-related macular degeneration. Ophthalmology 1989; 96:375-81.
46. Macular Photocoagulation Study Group. Five-year followup of fellow eyes of patients with age-related macular degeneration and unilateral extrafoveal choroidal neovascularization. Arch Ophthalmol 1993; 111:1189-99.
47. Macular Photocoagulation Study Group. Risk factors for choroidal neovascularization in the second eye of patients with juxtafoveal or subfoveal choroidal neovascularization secondary to age-related macular degeneration. Arch Ophthalmol 1997; 115:741-7.
48. Brown B, Kitchin JL. Dark adaptation and the acuity/luminance response in senile macular degeneration (SMD). Am J Optom Physiol Opt 1983; 60:645-50.
49. Brown B, Tobin C, Roche N, Wolanowski A. Cone adaptation in age-related maculopathy. Am J Optom Physiol Opt 1986; 63:450-4.
50. Sunness JS, Massof RW, Johnson MA, Finkelstein D, Fine SL. Peripheral retinal function in age-related macular degeneration. Arch Ophthalmol 1985; 103:811-6.
51. Brown B, Lovie-Kitchin J. Contrast sensitivity in central and paracentral retina in age-related maculopathy. Clin Exp Optom 1987; 70:145-8.
52. Midena E, Degli Angeli C, Blarzino MC, Valenti M, Segato T. Macular function impairment in eyes with early age-related macular degeneration. Invest Ophthalmol Vis Sci 1997; 38:469-77.
53. Applegate CA, Sunness JS, Haselwood DM. Visual symptoms associated with geographic atrophy from age-related macular degeneration. Invest Ophthalmol Vis Sci 1996; 37:S112.
54. Sunness JS, Applegate CA, Gonzalez-Baron J. Improvement of visual acuity over time in patients with bilateral geographic atrophy from age-related macular degeneration. Retina 2000; 20:162-9.
55. Guez JE, Le Gargasson JF, Rigaudiere F, O’Regan JK. Is there a systematic location for the pseudo-fovea in patients with central scotoma? Vis Res 1993; 9:1271-9.
56. Sloan L. Variation of acuity with luminance in ocular diseases and anomalies. Doc Ophthalmol 1969; 26:384-93.
57. Schuchard RA, Raasch TW. Retinal locus for fixation: pericentral fixation targets. Clin Vis Sci 1992; 7:511-20.
58. Lei H, Schuchard RA. Using two preferred retinal loci for different lighting conditions in patients with central scotomas. Invest Ophthalmol Vis Sci 1997; 38:1812-8.
59. Szlyk JP, Pizzimenti CE, Fishman GA, et al. A comparison of driving in older subjects with and without age-related macular degeneration. Arch Ophthalmol 1995; 113: 1033-40.
60. Bressler NM, Frost LA, Bressler SB, Murphy RP, Fine SL. Natural course of poorly defined choroidal neovascularization in macular degeneration. Arch Ophthalmol 1988; 106:1537-42.
61. Jalkh AE, Nasrallah FP, Marinelli I, Van de Velde F. Inactive subretinal neovascularization in age-related macular degeneration. Ophthalmology 1990; 97:1614-9.
62. Yeo JH, Marcus S, Murphy RP. Retinal pigment epithelial tears: patterns and progression. Ophthalmology 1988; 95:8-13.
63. Marmor MF, McNamara JA. Pattern dystrophy of the retinal pigment epithelium and geographic atrophy. Am J Ophthalmol 1996; 122:382-92.
64. Krill AE, Archer D. Classification of the choroidal atrophies. Am J Ophthalmol 1971; 72:562.
65. Holz FG, Bellmann C, Margaritidis M, Schutt F, Otto TP, Volcker HE. Patterns of increased in vivo autofluorescence in the junctional zone of geographic atrophy of the retinal pigment epithelium associated with age-related macular degeneration. Graefe’s Arch Clin Exp Ophthalmol 1999; 237:145-52.
66. Delori FC, Dorey CK, Staurenghi G, Arend O, Goger DG, Weiter JJ. In vivo fluorescence of the ocular fundus exhibits retinal pigment epithelium lipofuscin characteristics. Invest Ophthalmol Vis Sci 1995; 36:718-29.
67. Holz FG, Bellman C, Staudt S, Schutt F, Volcker HE. Fundus autofluorescence and development of geographic atrophy in age-related macular degeneration. Invest Ophthalmol Vis Sci 2001; 42:1051-6.
68. Deckert A, Deckert A, Schmitz-Valckenberg S, et al. Automated analysis of digital fundus autofluorescence images of geographic atrophy in advanced age-related macular degeneration using confocal scanning laser ophthalmoscopy (cSLO). BMC Ophthalmol 2005; 5(1):8.
69. Sunness JS, Ziegler MD, Applegate CA. Issues in quantifying atrophic macular disease using retinal autofluorescence. Retina 2006 Jul-Aug; 26(6):666-72.
70. Age-Related Eye Disease Study Research Group. A randomized, placebo-controlled, clinical trial of high-dose supplementation with vitamins C and E, beta carotene, and zinc for age-related macular degeneration and vision loss: AREDS report No. 8. Arch Ophthalmol 2001; 119:1417-36.
71. Weisz JM, deJuan E, Humayun MS, et al. Allogenic fetal retinal pigment epithelial cell transplant in a patient with geographic atrophy. Retina 1999; 19:540-5.