Short-course accelerated radiotherapy in palliative treatment of advanced pelvic malignancies: A phase i study

International Journal of Radiation Oncology Biology Physics

Volumn 83, Issue 5, 2012, Pages

  Caravatta, Luciana ^a   Padula, Gilbert D A ^b   MacChia, Gabriella ^a   Ferrandina, Gabriella ^a   Bonomo, Pierluigi ^a   Deodato, Francesco ^a   Massaccesi, Mariangela ^a   Mignogna, Samantha ^a   Tambaro, Rosa ^a   Rossi, Marco ^a   Flocco, Mariano ^c   Scapati, Andrea ^d   Scambia, Giovanni ^e   Pacelli, Fabio ^a   Valentini, Vincenzo ^e   Cellini, Numa ^e   Morganti, Alessio G ^a,e  

^a CATHOLIC UNIVERSITY   (Italy)

^b Saint Mary's Health Care   (United States)

^c 'Madre Teresa di Calcutta' Hospice ^*  (Italy)

^d SAN FRANCESCO HOSPITAL   (Italy)

^e CATHOLIC UNIVERSITY   (Italy)

Author keywords

Pain; Palliative care; Pelvic cancer; Quality of life; Radiotherapy

Indexed keywords

ACCELERATED RADIOTHERAPY; ACUTE TOXICITY; CONFIDENCE INTERVAL; DOSE LIMITING TOXICITY; EASTERN COOPERATIVE ONCOLOGY GROUP; LINEAR ANALOG SCALE; MAXIMUM TOLERATED DOSE; PAIN; PAIN RELIEF; PALLIATIVE CARE; PELVIC CANCER; PHASE I; PHASE II; QUALITY OF LIFE; RADIATION THERAPY ONCOLOGY GROUPS; RESPONSE RATE; SHORT-COURSE RADIOTHERAPY; TOTAL DOSE; TUMOR SITE; TWICE-DAILY FRACTIONS; VISUAL ANALOG SCALE;

DISEASES; ENZYME INHIBITION; HEALTH; ONCOLOGY; QUALITY CONTROL; RADIOTHERAPY;

TOXICITY;

ACUTE TOXICITY; ADULT; ADVANCED CANCER; AGED; ANALGESIA; ARTICLE; CANCER LINEAR ANALOG SCAL; CANCER RADIOTHERAPY; COHORT ANALYSIS; COLORECTAL CANCER; COLORECTAL CARCINOMA; COMPUTER ASSISTED TOMOGRAPHY; ENDOMETRIUM CARCINOMA; FEMALE; GASTROINTESTINAL TOXICITY; HUMAN; MAJOR CLINICAL STUDY; MALE; NEPHROTOXICITY; OVARY CARCINOMA; PELVIS CANCER; PRIMARY TUMOR; PRIORITY JOURNAL; PROSTATE ADENOCARCINOMA; QUALITY OF LIFE; RADIATION DOSE FRACTIONATION; RADIATION INJURY; RATING SCALE; TREATMENT RESPONSE; UNDIFFERENTIATED BLADDER CARCINOMA; UROTHELIAL BLADDER CARCINOMA; UTERINE CARCINOSARCOMA; UTERINE CERVIX CARCINOMA; VAGINAL CARCINOSARCOM; VISUAL ANALOG SCALE; VULVA MELANOMA;

AGED; AGED, 80 AND OVER; DOSE FRACTIONATION; FEMALE; GENITAL NEOPLASMS, FEMALE; HUMANS; MALE; MAXIMUM TOLERATED DOSE; MIDDLE AGED; PAIN MEASUREMENT; PALLIATIVE CARE; PELVIC NEOPLASMS; PROSTATIC NEOPLASMS; QUALITY OF LIFE; RADIATION INJURIES; RADIOTHERAPY PLANNING, COMPUTER-ASSISTED; RADIOTHERAPY, CONFORMAL; RECTAL NEOPLASMS; URINARY BLADDER NEOPLASMS;

EID: 84863627588     PISSN: 03603016     EISSN: 1879355X     Source Type: Journal    
DOI: 10.1016/j.ijrobp.2011.10.081     Document Type: Article

References (20)

1. S.T. Lutz, E.L. Chow, W.F. Hartsell, and A.A. Konski A review of hypofractionated palliative radiotherapy Cancer 109 2007 1462 1470
2. L. van Lonkhuijzen, and G. Thomas Palliative radiotherapy for cervical carcinoma, a systematic review Radiother Oncol 98 2011 287 291
3. World Health Organization Cancer pain relief and palliative care: a report of a WHO expert committee World Health Organ Tech Rep Ser 804 1990 1 75
4. R.S. Samant, E. Fitzgibbon, J. Meng, and I.D. Graham Family physicians' perspectives regarding palliative radiotherapy Radiother Oncol 78 2006 101 106
5. A. Vulto, M. van Bommel, P. Poortmans, M. Lybeert, M. Louwman, and R. Baart General practitioners and referral for palliative radiotherapy: a population-based survey Radiother Oncol 91 2009 267 270
6. S. Lutz, C. Spence, E. Chow, N. Janjan, and S. Connor Survey on utilization of palliative radiotherapy in hospice care J Clin Oncol 22 2004 3581 3586
7. O.S. Din, N. Thanvi, C.J. Ferguson, and P. Kirkbride Palliative prostate radiotherapy for symptomatic advanced prostate cancer Radiother Oncol 93 2009 192 196
8. R.J. Boulware, J.B. Caderao, L. Delclos, J.T. Wharton, and L.J. Peters Whole pelvis megavoltage irradiation with single doses of 1000 rad to palliate advanced gynecologic cancers Int J Radiat Oncol Biol Phys 5 1979 333 338
9. W.J. Spanos Jr. , T. Wasserman, R. Meoz, J. Sala, J. Kong, and J. Stetz Palliation of advanced pelvic malignant disease with large fraction pelvic radiation and misonidazole: final report of RTOG phase I/II study Int J Radiat Oncol Biol Phys 13 1987 1479 1482
10. W. Spanos Jr. , C. Guse, C. Perez, P. Grigsby, R.L. Doggett, and C. Poulter Phase II study of multiple daily fractionations in the palliation of advanced pelvic malignancies: preliminary report of RTOG 8502 Int J Radiat Oncol Biol Phys 17 1989 659 661
11. W.J. Spanos Jr. , C.A. Perez, S. Marcus, C.A. Poulter, R.L. Doggett, and A.D. Steinfeld Effect of rest interval on tumor and normal tissue response - a report of phase III study of accelerated split course palliative radiation for advanced pelvic malignancies (RTOG-8502) Int J Radiat Oncol Biol Phys 25 1993 399 403
12. R. Melzack The McGill pain questionnaire: major properties and scoring methods Pain 1 1975 277 299
13. O.M. Salazar, T. Sandhu, N.W. da Motta, M.A. Escutia, E. Lanzós-Gonzales, and A. Mouelle-Sone Fractionated half-body irradiation (HBI) for the rapid palliation of widespread, symptomatic, metastatic bone disease: a randomized Phase III trial of the International Atomic Energy Agency (IAEA) Int J Radiat Oncol Biol Phys 50 2001 765 775
14. H.J. Sutherland, P. Walker, and J.E. Till The development of a method for determining oncology patients' emotional distress using linear analogue scales Cancer Nurs 11 1988 303 308
15. S.G. Arbuck Workshop on phase I study design. Ninth NCI/EORTC New Drug Development Symposium, Amsterdam Ann Oncol 7 1996 567 573
16. J.D. Cox, J. Stetz, and T.F. Pajak Toxicity criteria of the Radiation Therapy Oncology Group (RTOG) and the European Organization for Research and Treatment of Cancer (EORTC) Int J Radiat Oncol Biol Phys 31 1995 1341 1346
17. H.R. Withers Biological basis of radiation therapy C.A. Perez, L.W. Brady, Principles and Practice of Radiation Oncology 1992 Lippincott Philadelphia, PA 64 69
18. International Commission on Radiation Units and Measurements ICRU Report 62: Prescribing, Recording and Reporting Photon Beam Therapy (Supplement to ICRU Report 50) 1999 ICRU Bethesda, MD
19. W.J. Spanos Jr. , M. Clery, C.A. Perez, P.W. Grigsby, R.L.S. Doggett, and C.A. Poulter Late effect of multiple daily fraction palliation schedule for advanced pelvic malignancies (RTOG 8502) Int J Radiat Oncol Biol Phys 29 1994 961 967
20. L.A. Carrascosa, C.M. Yashar, K.J. Paris, R.V. Larocca, S.R. Faught, and W.J. Spanos Palliation of pelvic and head and neck cancer with paclitaxel and a novel radiotherapy regimen J Palliat Med 10 2007 877 881