Structural basis for activation of an integral membrane protease by lipopolysaccharide

Journal of Biological Chemistry

Volumn 287, Issue 28, 2012, Pages 23971-23976

  Eren, Elif ^a   Van Den Berg, Bert ^a  

^a UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATION LOOPS; ACTIVE SITE; COCRYSTAL STRUCTURE; ENTEROBACTERIACEAE; ENZYMATIC ACTIVITIES; INTEGRAL MEMBRANE; LIPOPOLYSACCHARIDES; NATURAL SUBSTRATES; OUTER MEMBRANE; PEPTIDE SUBSTRATES; PHYSIOLOGICAL FUNCTIONS; PLASMINOGEN ACTIVATORS; STRUCTURAL BASIS; WATER MOLECULE; YERSINIA PESTIS;

ENZYME ACTIVITY; PEPTIDES;

CHEMICAL ACTIVATION;

ACTIVATION LOOP PEPTIDE; LIPOPOLYSACCHARIDE; MEMBRANE PROTEIN; OMPTIN; PLASMINOGEN; PLASMINOGEN ACTIVATOR; PROTEINASE; UNCLASSIFIED DRUG;

ARTICLE; COMPLEX FORMATION; CRYSTAL STRUCTURE; ENZYME ACTIVATION; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME STRUCTURE; ENZYME SUBSTRATE COMPLEX; MOLECULAR WEIGHT; NUCLEOPHILICITY; PRIORITY JOURNAL; PROTEIN DEGRADATION;

AMINO ACID SEQUENCE; BACTERIAL PROTEINS; BIOCATALYSIS; CATALYTIC DOMAIN; CRYSTALLOGRAPHY, X-RAY; ENZYME ACTIVATION; FIBRINOLYSIN; HUMANS; LIPOPOLYSACCHARIDES; MODELS, MOLECULAR; MUTATION; PEPTIDES; PLASMINOGEN; PLASMINOGEN ACTIVATORS; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN STRUCTURE, TERTIARY; PROTEOLYSIS; SERINE ENDOPEPTIDASES; SUBSTRATE SPECIFICITY; YERSINIA PESTIS;

ENTEROBACTERIACEAE; YERSINIA PESTIS;

EID: 84863617034     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.376418     Document Type: Article

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