Relative contributions of afferent vagal fibers to resistance to diet-induced obesity

Digestive Diseases and Sciences

Volumn 57, Issue 5, 2012, Pages 1281-1290

  Stearns, A T ^a,b   Ashley, S W ^a   Balakrishnan, A ^a,c   Rhoads, D B ^d   Radmanesh, A ^a   Tavakkolizadeh, A ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b UNIVERSITY OF OXFORD   (United Kingdom)

^c UNIVERSITY OF LIVERPOOL   (United Kingdom)

^d HARVARD MEDICAL SCHOOL   (United States)

Author keywords

Abdominal visceral fat; Bariatric surgery; Capsaicin; Vagotomy; Vagus

Indexed keywords

CAPSAICIN; GLUCOSE; HEMOGLOBIN A1C; SODIUM GLUCOSE COTRANSPORTER 1; AGENTS ACTING ON THE PERIPHERAL NERVOUS AND NEUROMUSCULAR SYSTEMS; SLC5A1 PROTEIN, RAT;

ABDOMINAL OBESITY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BODY COMPOSITION; BODY MASS; BODY WEIGHT; CALORIC INTAKE; CONTROLLED STUDY; DEAFFERENTATION; FAT CONTENT; GLUCOSE BLOOD LEVEL; GLUCOSE TRANSPORT; IMMUNOBLOTTING; INTRAABDOMINAL FAT; JEJUNUM; MALE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; OBESITY; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SMALL INTESTINE ABSORPTION; VAGOTOMY; VAGUS NERVE; WEIGHT GAIN; ANIMAL; DIAPHRAGM; DIET; DISEASE MODEL; DRUG EFFECT; INNERVATION; INTESTINE ABSORPTION; METABOLISM; METHODOLOGY; PATHOPHYSIOLOGY; SENSORY NERVE; SENSORY RECEPTOR; SPRAGUE DAWLEY RAT; TREATMENT OUTCOME;

AFFERENT PATHWAYS; ANIMALS; BODY WEIGHT; CAPSAICIN; DIAPHRAGM; DIET; DISEASE MODELS, ANIMAL; GLUCOSE; INTESTINAL ABSORPTION; INTRA-ABDOMINAL FAT; JEJUNUM; MALE; OBESITY; RATS; RATS, SPRAGUE-DAWLEY; SENSORY RECEPTOR CELLS; SENSORY SYSTEM AGENTS; SODIUM-GLUCOSE TRANSPORTER 1; TREATMENT OUTCOME; VAGOTOMY; VAGUS NERVE;

EID: 84863613632     PISSN: 01632116     EISSN: 15732568     Source Type: Journal    
DOI: 10.1007/s10620-011-1968-4     Document Type: Article

References (42)

1. Buchwald H, Avidor Y, Braunwald E, et al. Bariatric surgery: a systematic review and meta-analysis. JAMA. 2004;292: 1724-1737. doi:10.1001/jama.292.14. 1724.
2. Boss TJ, Peters J, Patti MG, Lustig RH, Kral JG. Laparoscopic truncal vagotomy for severe obesity: six month experience in 10 patients from a prospective, two-center study. Surg Obes Relat Dis. 2007;3:292.
3. Kral JG. Vagotomy for treatment of severe obesity. Lancet. 1978;1:307-308.
4. Kral JG. Effects of truncal vagotomy on body weight and hyperinsulinemia in morbid obesity. Am J Clin Nutr. 1980;33: 416-419.
5. Camilleri M, Toouli J, Herrera MF, et al. Intra-abdominal vagal blocking (VBLOC therapy): clinical results with a new implantable medical device. Surgery. 2008;143:723-731. doi: 1016/j.surg.2008.03.015.
6. Stearns AT, Balakrishnan A, Rounds J, Rhoads DB, Ashley SW, Tavakkolizadeh A. Capsaicin-sensitive vagal afferents modulate posttranscriptional regulation of the rat Na?/glucose cotransporter SGLT1. Am J Physiol Gastrointest Liver Physiol. 2008;294:G1078-G1083. doi:10.1152/ajpgi. 00591.2007.
7. Martin MG, Lostao MP, Turk E, Lam J, Kreman M, Wright EM. Compound missense mutations in the sodium/D-glucose cotransporter result in trafficking defects. Gastroenterology. 1997;112: 1206-1212.
8. Johnston KL, Clifford MN, Morgan LM. Possible role for apple juice phenolic, compounds in the acute modification of glucose tolerance and gastrointestinal hormone secretion in humans. J Sci Food Agric. 2002;82:1800-1805.
9. Rossetti L, Smith D, Shulman GI, Papachristou D, Defronzo RA. Correction of hyperglycemia with phlorizin normalizes tissue sensitivity to insulin in diabetic rats. J Clin Invest. 1987;79: 1510-1515.
10. Melnyk A, Himms-Hagen J. Resistance to aging-associated obesity in capsaicin-desensitized rats one year after treatment. Obes Res. 1995;3:337-344.
11. Balakrishnan A, Stearns AT, Rounds J, et al. Diurnal rhythmicity in glucose uptake is mediated by temporal periodicity in the expression of the sodium-glucose cotransporter (SGLT1). Surgery. 2008;143:813-818. doi:10.1016/j.surg.2008.03.018.
12. Stearns AT, Balakrishnan A, Rhoads DB, Ashley SW, Tavakkolizadeh A. Diurnal expression of the rat intestinal sodium-glucose cotransporter 1 (SGLT1) is independent of local luminal factors. Surgery. 2009;145:294-302. doi:10.1016/j.surg.2008.
13. Folch J, Lees M, Sloane Stanley GH. A simple method for the isolation and purification of total lipides from animal tissues. J Biol Chem. 1957;226:497-509.
14. Kral JG, Gortz L. Truncal vagotomy in morbid obesity. Int J Obes. 1981;5:431-435.
15. Kral JG. Vagotomy as a treatment for morbid obesity. Surg Clin North Am. 1979;59:1131-1138.
16. Kral JG, Gortz L, Hermansson G, Wallin GS. Gastroplasty for obesity: long-term weight loss improved by vagotomy. World J Surg. 1993;17:75-78.
17. Angrisani L, Cutolo PP, Ciciriello MB, et al. Laparoscopic adjustable gastric banding with truncal vagotomy versus laparoscopic adjustable gastric banding alone: interim results of a prospective randomized trial. Surg Obes Relat Dis. 2009;5: 435-438. doi:10.1016/j.soard.2008.08.024.
18. Ferrari B, Arnold M, Carr RD, et al. Subdiaphragmatic vagal deafferentation affects body weight gain and glucose metabolism in obese male Zucker (fa/fa) rats. Am J Physiol Regul Integr Comp Physiol. 2005;289:R1027-R1034. doi:10.1152/ajpregu. 00736.2004.
19. Fox CS, Massaro JM, Hoffmann U, et al. Abdominal visceral and subcutaneous adipose tissue compartments: association with metabolic risk factors in the Framingham heart study. Circulation. 2007;116:39-48. doi:10.1161/circulationaha.106.675355.
20. Nguyen-Duy TB, Nichaman MZ, Church TS, Blair SN, Ross R. Visceral fat and liver fat are independent predictors of metabolic risk factors in men. Am J Physiol Endocrinol Metab. 2003;284:E1065-E1071. doi:10.1152/ajpendo.00442. 200200442. 2002.
21. Banerji MA, Buckley MC, Chaiken RL, Gordon D, Lebovitz HE, Kral JG. Liver fat, serum triglycerides and visceral adipose tissue in insulin-sensitive and insulin-resistant black men with NIDDM. Int J Obes Relat Metab Disord. 1995;19:846-850.
22. Diamant M, Lamb HJ, van de Ree MA, et al. The association between abdominal visceral fat and carotid stiffness is mediated by circulating inflammatory markers in uncomplicated type 2 diabetes. J Clin Endocrinol Metab. 2005;90:1495-1501. doi: 1210/jc.2004-1579.
23. Despres JP, Lemieux S, Lamarche B, et al. The insulin resistancedyslipidemic syndrome: contribution of visceral obesity and therapeutic implications. Int J Obes Relat Metab Disord. 1995;19:S76-S86.
24. Kuk JL, Katzmarzyk PT, Nichaman MZ, Church TS, Blair SN, Ross R. Visceral fat is an independent predictor of all-cause mortality in men. Obesity (Silver Spring). 2006;14:336-341. doi:1038/oby.2006.43.
25. Carroll JF, Franks SF, Smith AB, Phelps DR. Visceral adipose tissue loss and insulin resistance 6 months after laparoscopic gastric banding surgery: a preliminary study. Obes Surg. 2009;19:47-55. doi:10.1007/s11695-008-9642-4.
26. Powley TL, Chi MM, Baronowsky EA, Phillips RJ. Gastrointestinal tract innervation of the mouse: afferent regeneration and meal patterning after vagotomy. Am J Physiol Regul Integr Comp Physiol. 2005;289:R563-R574. doi:10.1152/ajpregu.00167.2005.
27. Phillips RJ, Baronowsky EA, Powley TL. Long-term regeneration of abdominal vagus: efferents fail while afferents succeed. J Comp Neurol. 2003;455:222-237. doi:10.1002/cne.10470.
28. Phillips RJ, Baronowsky EA, Powley TL. Regenerating vagal afferents reinnervate gastrointestinal tract smooth muscle of the rat. J Comp Neurol. 2000;421:325-346. doi:10.1002/(SICI)1096- 9861(20000605)421:3\325:AID-CNE3[3.0. CO;2-9.
29. Ritter RC, Ladenheim EE. Capsaicin pretreatment attenuates suppression of food intake by cholecystokinin. Am J Physiol. 1985;248:R501-R504.
30. Mordes JP, Lozy ME, Herrera MG, Silen W. Effects of vagotomy with and without pyloroplasty on weight and food-intake in rats. Am J Physiol. 1979;236:R61-R66.
31. Murphy KG, Bloom SR. Gut hormones and the regulation of energy homeostasis. Nature. 2006;444:854-859. doi:10.1038/nature05484.
32. Badman MK, Flier JS. The gut and energy balance: visceral allies in the obesity wars. Science. 2005;307:1909-1914. doi:10.1126/science.1109951.
33. Leung FW, Go VL, Scremin OU, et al. Pilot studies to demonstrate that intestinal mucosal afferent nerves are functionally linked to visceral adipose tissue. Dig Dis Sci. 2007;52: 2695-2702. doi:10.1007/s10620-006-9645-8.
34. Pardo JV, Sheikh SA, Kuskowski MA, et al. Weight loss during chronic, cervical vagus nerve stimulation in depressed patients with obesity: an observation. Int J Obes (Lond). 2007;31: 1756-1759. doi:10.1038/sj.ijo.0803666
35. Esposito G, Faelli A, Tosco M, Orsenigo MN, Battistessa R. Agerelated changes in rat intestinal transport of D-glucose, sodium, and water. Am J Physiol. 1985;249:G328-G334.
36. Vincenzini MT, Iantomasi T, Stio M, et al. Glucose transport during ageing by human intestinal brush-border membrane vesicles. Mech Ageing Dev. 1989;48:33-41.
37. Stearns AT, Balakrishnan A, Tavakkolizadeh A. Impact of Roux-en-Y gastric bypass surgery on rat intestinal glucose transport. Am J Physiol Gastrointest Liver Physiol. 2009;297: G950-G957.
38. Dyer J, Wood IS, Palejwala A, Ellis A, Shirazi-Beechey SP. Expression of monosaccharide transporters in intestine of diabetic humans. Am J Physiol Gastrointest Liver Physiol. 2002;282: G241-G248. doi:10.1152/ajpgi.00310.2001.
39. Gram DX, Ahren B, Nagy I, et al. Capsaicin-sensitive sensory fibers in the islets of Langerhans contribute to defective insulin secretion in Zucker diabetic rat, an animal model for some aspects of human type 2 diabetes. Eur J Neurosci. 2007;25: 213-223. doi:10.1111/j.1460-9568.2006.05261.x.
40. Gram DX, Hansen AJ, Wilken M, et al. Plasma calcitonin generelated peptide is increased prior to obesity, and sensory nerve desensitization by capsaicin improves oral glucose tolerance in obese Zucker rats. Eur J Endocrinol. 2005;153:963-969. doi: 1530/eje.1.02046.
41. Gram DX, Hansen AJ, Deacon CF, et al. Sensory nerve desensitization by resiniferatoxin improves glucose tolerance and increases insulin secretion in Zucker Diabetic Fatty rats and is associated with reduced plasma activity of dipeptidyl peptidase IV. Eur J Pharmacol. 2005;509:211-217. doi:10.1016/j. ejphar. 2004.12.039.
42. Motter AL, Ahern GP. TRPV1-null mice are protected from dietinduced obesity. FEBS Lett. 2008;582:2257-2262.