A TSHR-LH/CGR chimera that measures functional thyroid-stimulating autoantibodies (TSAb) can predict remission or recurrence in Graves' patients undergoing antithyroid drug (ATD) treatment

Journal of Clinical Endocrinology and Metabolism

Volumn 97, Issue 7, 2012, Pages

  Giuliani, Cesidio ^a   Cerrone, Dominique ^a   Harii, Norikazu ^b   Thornton, Mark ^b   Kohn, Leonard D ^b   Dagia, Nilesh M ^c,e   Bucci, Ines ^a   Carpentieri, Maria ^a   Di Nenno, Barbara ^a   Di Blasio, Andrea ^a   Vitti, Paolo ^d   Monaco, Fabrizio ^a   Napolitano, Giorgio ^a  

^a UNIVERSITY OF CHIETI   (Italy)

^b OHIO UNIVERSITY   (United States)

^c US Institute of Navigation   (United States)

^d UNIVERSITY OF PISA   (Italy)

^e Piramal Enterprises Limited   (India)

Author keywords

[No Author keywords available]

Indexed keywords

ANTITHYROID AGENT; AUTOANTIBODY; PROPYLTHIOURACIL; THIAMAZOLE; THYROID STIMULATING IMMUNOGLOBULIN; THYROTROPIN RECEPTOR; THYROTROPIN RECEPTOR ANTIBODY;

ADULT; ANTIBODY DETECTION; ANTIBODY TITER; ARTICLE; CHIMERA; CONTROLLED STUDY; FEMALE; GRAVES DISEASE; HUMAN; HUMAN CELL; HYPERTHYROIDISM; MAJOR CLINICAL STUDY; MALE; ORGAN SIZE; PREDICTIVE VALUE; PRIORITY JOURNAL; PROGNOSIS; PROTEIN DETERMINATION; RECURRENT DISEASE; REMISSION; SENSITIVITY AND SPECIFICITY; TREATMENT DURATION;

ADULT; ANIMALS; ANTITHYROID AGENTS; AUTOANTIBODIES; CHO CELLS; CLINICAL TRIALS AS TOPIC; CRICETINAE; CRICETULUS; FEMALE; FOLLOW-UP STUDIES; GRAVES DISEASE; HEK293 CELLS; HUMANS; IMMUNOGLOBULINS, THYROID-STIMULATING; MALE; MIDDLE AGED; PREDICTIVE VALUE OF TESTS; PROGNOSIS; RECEPTORS, LH; RECEPTORS, THYROTROPIN; RECOMBINANT FUSION PROTEINS; RECURRENCE; REMISSION INDUCTION; THYROID FUNCTION TESTS; YOUNG ADULT;

EID: 84863605672     PISSN: 0021972X     EISSN: 19457197     Source Type: Journal    
DOI: 10.1210/jc.2011-2897     Document Type: Article

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