Label-free epitope binning assays of monoclonal antibodies enable the identification of antigen heterogeneity

Journal of Immunological Methods

Volumn 382, Issue 1-2, 2012, Pages 101-116

  Abdiche, Yasmina N ^a   Lindquist, Kevin C ^a   Stone, Donna M ^a   Rajpal, Arvind ^a   Pons, Jaume ^a  

^a PFIZER INC   (United States)

Author keywords

Antigen heterogeneity; Biosensor; Epitope; Epitope binning; Monoclonal antibody

Indexed keywords

ANTIGEN; EPITOPE; FATTY ACID BINDING PROTEIN 4; FC RECEPTOR; KEXIN; KEXIN TYPE 9; MONOCLONAL ANTIBODY; PROGRANULIN; UNCLASSIFIED DRUG;

ANTIBODY TITER; ANTIGEN BINDING; ARTICLE; ASSAY; BINDING AFFINITY; BINNING ASSAY; BIOSENSOR; CONTROLLED STUDY; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IN VITRO STUDY; KINETICS; PHOSPHORYLATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; WESTERN BLOTTING;

ANTIBODIES, MONOCLONAL; ANTIGEN-ANTIBODY REACTIONS; ANTIGENS; BIOSENSING TECHNIQUES; EPITOPES; FATTY ACID-BINDING PROTEINS; GLIAL CELL LINE-DERIVED NEUROTROPHIC FACTOR RECEPTORS; HEK293 CELLS; HUMANS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MOLECULAR SEQUENCE DATA;

EID: 84863598239     PISSN: 00221759     EISSN: 18727905     Source Type: Journal    
DOI: 10.1016/j.jim.2012.05.010     Document Type: Article

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