Plasma pyridoxal-5-phosphate is inversely associated with systemic markers of inflammation in a population of U.S. Adults

Journal of Nutrition

Volumn 142, Issue 7, 2012, Pages 1280-1285

  Sakakeeny, Lydia ^a   Roubenoff, Ronenn ^b   Obin, Martin ^a   Fontes, Joao D ^c   Benjamin, Emelia J ^c   Bujanover, Yoram ^d   Jacques, Paul F ^a   Selhub, Jacob ^a  

^a TUFTS UNIVERSITY   (United States)

^b TUFTS UNIVERSITY   (United States)

^c BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d TEL AVIV UNIVERSITY   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

ACUTE PHASE PROTEIN; C REACTIVE PROTEIN; CELL ADHESION MOLECULE; CYTOKINE; GLYCINE HYDROXYMETHYLTRANSFERASE; PYRIDOXAL 5 PHOSPHATE; PYRIDOXINE; TRYPTOPHAN;

ADULT; AGED; ARTICLE; CARDIOVASCULAR DISEASE; DIABETES MELLITUS; DIETARY INTAKE; ENTERITIS; FEMALE; HUMAN; INFLAMMATION; MAJOR CLINICAL STUDY; MALE; OXIDATIVE STRESS; PYRIDOXINE DEFICIENCY; RHEUMATOID ARTHRITIS; TRYPTOPHAN METABOLISM; UNITED STATES;

AGED; BIOLOGICAL MARKERS; C-REACTIVE PROTEIN; FEMALE; HUMANS; INFLAMMATION; INFLAMMATION MEDIATORS; MALE; MULTIVARIATE ANALYSIS; NUTRITIONAL STATUS; OXIDATIVE STRESS; PYRIDOXAL PHOSPHATE; UNITED STATES; VITAMIN B DEFICIENCY;

EID: 84863550129     PISSN: 00223166     EISSN: 15416100     Source Type: Journal    
DOI: 10.3945/jn.111.153056     Document Type: Article

References (41)

1. Verhoef P, Stampfer M, Buring J, Gaziano J, Allen R, Stabler S, Reynolds RD, Kok FJ, Hennekens C, Willett WC. Homocysteine metabolism and risk of myocardial infarction: relation with vitamins B6, B12, and folate. Am J Epidemiol. 1996;143:845-59.
2. Siri PW, Verhoef P, Kok FJ. Vitamins B6, B12, and folate: association with plasma total homocysteine and risk of coronary atherosclerosis. J Am Coll Nutr. 1998;17:435-41.
3. Kelly PJ, Shih VE, Kistler JP, Barron M, Lee H, Mandell R, Furie KL. Low vitamin B6 but not homocyst(e)ine is associated with increased risk of stroke and transient ischemic attack in the era of folic acid grain fortification. Stroke. 2003;34:e51-4.
4. Vermaak WJ, Barnard HC, Potgieter GM, Marx JD. Plasma pyridoxal-59-phosphate levels in myocardial infarction. S Afr Med J. 1986;70: 195-6.
5. Kok FJ, Schrijver J, Hofman A, Witteman J, Kruyssen D, Remme WJ, Low Vitamin HAV. B6 status in patients with acute myocardial infarction. Am J Cardiol. 1989;63:513-6.
6. Roubenoff R, Selhub J, Nadeau MR, Cannon JG, Freeman LM, Dinarello CA, Rosenberg IH. Abnormal vitamin B6 status in rheumatoid cachexia. Arthritis Rheum. 1995;38:105-9.
7. Chiang E-PSD, Selhub J, Dallal G, Wang Y-C, Roubenoff R. Inflammation causes tissue-specific depletion of vitamin B6. Arthritis Res Ther. 2005;7:R1254-62.
8. Bekpinar S, Kocak H, Unlucerci Y, Genc S, Akdag-Kose A, Gogus F. The evaluation of C-reactive protein, homocysteine and vitamin B6 concentrations in Behcet and rheumatoid arthritis disease. Clin Chim Acta. 2003;329:143-5.
9. Woolf K, Manore MM. Elevated plasma homocysteine and low vitamin B-6 status in nonsupplementing older women with rheumatoid arthritis. J Am Diet Assoc. 2008;108:443-53, discussion 54.
10. Saibeni S, Cattaneo M, Vecchi M, Zighetti L, Lecchi A, Lombardi R, Meucci G, Spina L, de Franchis R. Low vitamin B6 plasma levels, a risk factor for thrombosis in IBS: role of inflammation and correlation with acute phase reactants. Am J Gastroenterol. 2003;98:112-7.
11. Kuroki F, Iida M, Tominaga M, Matsumoto T, Hirakawa K, Sugiyama S, Fujishima M. Multiple vitamin status in Crohn's disease. Correlation with disease activity. Dig Dis Sci. 1993;38:1614-8.
12. Davis RE, Calder JS, Curnow DH. Serum pyridoxal and folate concentrations in diabetics. Pathology. 1976;8:151-6.
13. Wilson RG, Davis RE. Serum pyridoxal concentrations in children with diabetes mellitus. Pathology. 1977;9:95-8.
14. Ross R. Atherosclerosis: an inflammatory disease. N Engl J Med. 1999; 340:115-26.
15. Powell LJ. C-reactive protein: a review. Am J Med Technol. 1979;45: 138-42.
16. de Ferranti S, Rifai N. C-reactive protein and cardiovascular disease: a review of risk prediction and interventions. Clin Chim Acta. 2002; 317:1-15.
17. Morris MS, Sakakeeny L, Jacques PF, Picciano MF, Selhub J. Vitamin B-6 intake is inversely related to, and the requirement is affected by inflammation status. J Nutr. 2010;140:103-10.
18. Kelly PJ, Kistler JP, Shih VE, Mandell R, Atassi N, Barron M, Lee H, Silveira S, Furie KL. Inflammation, homocysteine, and vitamin B6 status after ischemic stroke. Stroke. 2004;35:12-5.
19. Gori A, Sofi F, Corsi A, Gazzini A, Sestini I, Lauretani F, Bandinelli S, Gensini G, Ferruci L, Abbate R. Predictors of vitamin B6 and folate concentrations in older persons: The InCHIANTI Study. Clin Chem. 2006;52:1318-24.
20. Friso S, Jacques PF, Wilson PW, Rosenberg IH, Selhub J. Low circulating vitamin B(6) is associated with elevation of the inflammation marker C-reactive protein independently of plasma homocysteine levels. Circulation. 2001;103:2788-91.
21. Kannel WB, Feinleib M, McNamara PM, Garrison RJ, Castelli WP. An investigation of coronary heart disease in families. The Framingham Offspring Study. Am J Epidemiol. 1979;110:281-90.
22. Camp VM, Chipponi J, Faraj BA. Radioenzymatic assay for direct measurement of plasma pyridoxal 59- phosphate. Clin Chem. 1983;29: 642-4.
23. Clauss A. Rapid physiological coagulation method in determination of fibrinogen. Acta Haematol. 1957;17:237-46.
24. Schnabel RB, Lunetta KL, Larson MG, Dupuis J, Lipinska I, Rong J, Chen M-H, Zhao Z, Yamamoto JF, Meigs JB, et al. The relation of genetic and environmental factors to systemic inflammatory biomarker concentrations. Circ Cardiovasc Genet. 2009;2:229-37.
25. Willett WC, Sampson L, Stampfer MJ, Rosner B, Bain C, Witschi J, Hennekens CH, Speizer FE. Reproducibility and validity of a semiquantitative food frequency questionnaire. Am J Epidemiol. 1985;122:51-65.
26. Araki A, Sako Y. Determination of free and total homocysteine in human plasma by high-performance liquid chromatography with fluorescence detection. J Chromatogr. 1987;422:43-52.
27. Tamura T, Freeberg LE, Cornwell PE. Inhibition of EDTA of growth of Lactobacillus casei in the folate microbiological assay and its reversal by added manganese or iron. Clin Chem. 1990;36:1993.
28. McNamara JR, Schaefer EJ. Automated enzymatic standardized lipid analyses for plasma and lipoprotein fractions. Clin Chim Acta. 1987;166:1-8.
29. Jaffe M. gber den Niederschlag welchem Pikrins@ure in normalem Harn erzeugt and hber eine neue Reaktion des Kreatinins. Z Phys Chem. 1886;10:391-400.
30. Food and Nutrition Board, Institute of Medicine. Dietary reference intakes for thiamin, riboflavin, niacin, vitamin B6, folate, vitamin B12, pantothenic acid, biotin, and choline. A report of the Standing Committee on the Scientific Evaluation of Dietary Reference Intakes and its Panel on Folate, Other B Vitamins, and Choline and Subcommittee on Upper Reference Levels of Nutrients. Washington, DC: National Academies Press; 1998.
31. Chiang EP, Selhub J, Bagley PJ, Dallal G, Roubenoff R. Pyridoxine supplementation corrects vitamin B6 deficiency but does not improve inflammation in patients with rheumatoid arthritis. Arthritis Res Ther. 2005;7:R1404-11.
32. Shen J, Lai C-Q, Mattei J, Ordovas JM, Tucker KL. Association of vitamin B-6 status with inflammation, oxidative stress, and chronic inflammatory conditions: the Boston Puerto Rican Health Study. Am J Clin Nutr. 2010;91:337-42.
33. Bates CJ, Pentieva KD, Prentice A, Mansoor MA, Finch S. Plasma pyridoxal phosphate and pyridoxic acid and their relationship to plasma homocysteine in a representative sample of British men and women aged 65 years and over. Br J Nutr. 1999;81:191-201.
34. Schumacher HR, Bernhart FW, Gyorgy P. Vitamin B6 levels in rheumatoid arthritis: effect of treatment. Am J Clin Nutr. 1975;28:1200-3.
35. Bleie Ø, Semb AG, Grundt H, Nordrehaug JE, Vollset SE, Ueland P, Nilsen DW, Bakken AM, Refsum H, Nygard OK. Homocysteinelowering therapy does not affect inflammatory markers of athersclerosis in patients with stable coronary artery disease. J Intern Med. 2007; 262:244-53.
36. Keszthelyi D, Troost FJ, Masclee AA. Understanding the role of tryptophan and serotonin metabolism in gastrointestinal function. Neurogastroenterol Motil. 2009;21:1239-49.
37. Papaspyridonos M, Smith A, Burnand KG, Taylor P, Padayachee S, Suckling KE, James CH, Greaves DR, Patel L. Novel candidate genes in unstable areas of human atherosclerotic plaques. Arterioscler Thromb Vasc Biol. 2006;26:1837-44.
38. King NJ, Thomas SR. Molecules in focus: indoleamine 2,3-dioxygenase. Int J Biochem Cell Biol. 2007;39:2167-72.
39. Schirch L. Serine hydroxymethyltransferase. Adv Enzymol Relat Areas Mol Biol. 1982;53:83-112.
40. Trakatellis A, Exindari M, Scountzou J, Koliakos G, Christodoulou D, Malissiovas N, Antoniadis A, Pohlyzoni Th. Effect of pyridoxine deficiency on immunological phenomena. Postgrad Med J. 1992;68: S70-7.
41. Ervin RB, Wright JD, Wang CY, Kennedy-Stephenson J. Dietary intake of selected vitamins for the United States population: 1999-2000. Adv Data. 2004:1-4.