Controllable preparation of polyacrylamide hydrogel microspheres in a coaxial microfluidic device

Industrial and Engineering Chemistry Research

Volumn 51, Issue 26, 2012, Pages 9016-9022

  Yang, Bodong ^a   Lu, Yangcheng ^a   Luo, Guangsheng ^a  

^a TSINGHUA UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ABSORBENT CAPACITIES; ACRYLAMIDE MONOMERS; HEAT BATH; HYDROGEL MICROSPHERES; MICRO-FLUIDIC DEVICES; MONO-DISPERSED; MONOMER SOLUTIONS; N-OCTANES; POLYACRYLAMIDE HYDROGELS; POLYACRYLAMIDES; REACTION TEMPERATURE; SKELETON STRUCTURE;

AMIDES; DEIONIZED WATER; FLUIDIC DEVICES; HYDROGELS; MONOMERS; POLYMERIZATION;

MICROSPHERES;

EID: 84863533917     PISSN: 08885885     EISSN: 15205045     Source Type: Journal    
DOI: 10.1021/ie3004013     Document Type: Conference Paper

References (45)

1. Brannon-Peppas, L.; Peppas, N. A. Dynamic and equilibrium swelling behavior of pH-sensitive hydrogels containing 2-hydroxyethyl methacrylate Biomaterials 1990, 11, 635
2. Ghandehari, H.; Kopeckova, P.; Kopecek, J. In vitro degradation of pH-sensitive hydrogels containing aromatic azo bonds Biomaterials 1997, 18, 861
3. Gemeinhart, R. A.; Chen, J.; Park, H.; Park, K. pH-sensitivity of fast responsive superporous hydrogels J. Biomater. Sci.-Polym. Ed. 2000, 11, 1371
4. Zhao, Q; Sun, J. Z.; Lin, Y. T.; Zhou, Q. Y. Macroporous double-network cryogels: Formation mechanism, enhanced mechanical strength and temperature/pH dual sensitivity Soft. Matter. 2011, 7, 602
5. Hirose, Y.; Amiya, T.; Hirokawa, Y.; Tanaka, T. Phase-transition of submicron gel beads Macromolecules 1987, 20, 1342
6. Tanaka, T.; Sato, E.; Hirokawa, Y.; Hirotsu, S. Peetermans, Critical kinetics of volume phase-transition of gels J. Phys. Rev. Lett. 1985, 55, 2455
7. Schild, H. G. Poly (N -isopropylacrylamide) - experiment, theory and application Prog. Polym. Sci. 1992, 17, 163
8. Brownlee, M.; Cerami, A. Glucose-controlled insulin-delivery system-Semi-synthesis insulin bound to lectin Science 1979, 206, 1190
9. Lee, S. J.; Park, K. Synthesis and characterization of sol-gel phase-reversible hydrogels sensitive to glucose J. Mol. Recognit. 1996, 9, 549
10. Park, T. G.; Hoffman, A. S. Sodium chloride-induced phase transition in nonionic poly(N -isopropylacrylamide) gel Macromolecules 1993, 26, 5045
11. Plunkett, K. N.; Kraft, M. L.; Yu, Q.; Moore, J. S. Swelling kinetics of disulfide cross-linked microgels Macromolecules 2003, 36, 3960
12. Bromberg, L.; Temchenko, M.; Alakhov, V.; Hatton, T. A. Kinetics of swelling of polyether-modified poly(acrylic acid) microgels with permanent and degradable cross-links Langmuir 2005, 21, 1590
13. Ghandehari, H.; Kopeckova, P.; Kopecek, J. In vitro degradation of pH-sensitive hydrogels containing aromatic azo bonds Biomaterials 1997, 18, 881
14. Chen, J.; Blevins, W. E.; Park, H.; Park, K. Gastric retention properties of superporous hydrogel composites J. Controlled Release 2000, 64, 39
15. Dorkoosh, F. A.; Verhoef, J. C.; Borchard, G.; Rafiee-Tehrani, M.; Junginger, H. E. Development and characterization of a novel peroral peptide drug delivery system J. Controlled Release 2001, 71, 307
16. Ichikawa, H.; Fukumori, Y. A novel positively thermosensitive controlled-release microcapsule with membrane of nano-sized poly(N -isopropylacrylamide) gel dispersed in ethylcellulose matrix J. Controlled Release 2000, 63, 107
17. Beebe, D. J.; Moore, J. S.; Bauer, J. M.; Yu, Q.; Liu, R. H.; Devadoss, C.; Jo, B. H. Functional hydrogel structures for autonomous flow control inside microfluidic channels Nature 1997, 389, 829
18. Bashir, R.; Hilt, J. Z.; Elibol, O.; Gupta, A.; Peppas, N. A. Micromechanical cantilever as an ultrasensitive pH microsensor Appl. Phys. Lett. 2002, 81, 3091
19. Zhang, Y. F.; Ji, H. F.; Snow, D.; Sterling, R.; Brown, G. M. A pH sensor based on a microcantilever coated with intelligent hydrogel Instrum. Sci. Technol. 2004, 32, 361
20. Ali, A. E. H.; Shawky, H. A.; Abd el Rehim, H. A.; Hegazy, E. A. Synthesis and characterization of PVP/AAc copolymer hydrogel and its applications in the removal of heavy metals from aqueous solution Eur. Polym. J. 2003, 39, 2337
21. Bolto, B.; Gregory, J. Organic polyelectrolytes in water treatment Water Res. 2007, 41, 2301
22. Atta, A. M.; Ismail, H. S.; Mohamed, H. M.; Mohamed, Z. M. Acrylonitrile/acrylamidoxime/2-acrylamido-2-methylpropane sulfonic acid-based hydrogels: synthesis, characterization and their application in the removal of heavy metals J. Appl. Polym. Sci. 2011, 122, 999
23. Ju, X. J.; Zhang, S. B.; Zhou, M. Y.; Xie, R.; Yang, L. H.; Chu., L. Y. Novel heavy-metal adsorption material: ion-recognition P(NIPAM-co-BCAm) hydrogels for removal of lead(II) ions J. Hazard. Mater. 2009, 167, 114
24. Patel, A. M.; Patel, R. G.; Patel, M. P. Nickel and copper removal study from aqueous solution using new cationic poly[acrylamide/ N, N -DAMB/ N, N -DAPB] super absorbent hydrogel J. Appl. Polym. Sci. 1998, 67, 177
25. Kidane, A.; Szabocsik, J. M.; Park, K. Accelerated study on lysozyme deposition on poly(HEMA) contact lenses Biomaterials 1998, 19, 2051
26. Dong, L.; Agarwal, A. K.; Beebe, D. J.; Jiang, H. R. Adaptive liquid microlenses activated by stimuli-responsive hydrogels Nature 2006, 442, 551
27. Lee, K. Y.; Mooney, D. J. Hydrogels for tissue engineering Chem. Rev. 2001, 101, 1869
28. Nguyen, K. T.; West, J. L. Photopolymerizable hydrogels for tissue engineering applications Biomaterials 2002, 23, 4307
29. Wilks, E. S., Industial Polymers Handbook; WILEY-VCH press: Germany, 2001.
30. Ma, S. M.; Liu, M. Z.; Chen, Z. B. Preparation and properties of a salt-resistant superabsorbent polymer J. Appl. Polym. Sci. 2004, 93, 2532
31. Utada, A. S.; Fernandez-Nieves, A.; Stone, H. A.; Weitz, D. A. Dripping to jetting transitions in coflowing liquid streams Phys. Rev. Lett. 2007, 99, 094502
32. Nie, Z. H.; Xu, S. Q.; Seo, M.; Lewis, P. C.; Kumacheva, E. Polymer particles with various shapes and morphologies produced in continuous microfluidic reactors J. Am. Chem. Soc. 2005, 127, 8058
33. Kim, J. W.; Utada, A. S.; Fernandez-Nieves, A.; Hu, Z. B.; Weitz, D. A. Fabrication of monodisperse gel shells and functional microgels in microfluidic devices Angew. Chem.-Int. Ed. 2007, 46, 1819
34. Xu, J. H.; Li, S. W.; Tan, J.; Wang, Y. J.; Luo, G. S. Controllable preparation of monodisperse O/W and W/O emulsions in the same microfluidic device Langmuir 2006, 22, 7943
35. Martynov, S.; Wang, X. L.; Stride, E. P.; Edirisinghe, M. J. Preparation of a micro-porous alginate gel using a microfluidic bubbling device Int. J. Food Eng. 2010, 6, 1
36. Gunther, A.; Jensen, K. F. Multiphase microfluidics: from flow characteristics to chemical and materials synthesis Lab Chip. 2007, 6, 1487
37. Lee, H.; Jeong, Y.; Shin, J.; Baek, J.; Kang, M.; Chun, K. Package embedded heat exchanger for stacked multi-chip module Sens. Actuators, A 2004, 114, 204
38. Lee, J.; Mudawar, I. Two-phase flow in high-heat-flux micro-channel heat sink for refrigeration cooling applications: Part I-Pressure drop characteristics Int. J. Heat Mass Transf. 2004, 48, 941
39. Jeong, W. J.; Kim, J. Y.; Choo, J.; Lee, E. K.; Han, C. S.; Beebe, D. J.; Seong, G. H.; Lee, S. H. Continuous fabrication of biocatalyst immobilized microparticles using photopolymerization and immiscible liquids in microfluidic systems Langmuir 2005, 21, 3738
40. Shah, R. K.; Kim, J. W.; Agresti, J. J.; Weitz, D. A.; Chu, L. Y. Fabrication of monodisperse thermosensitive microgels and gel capsules in microfluidic devices Soft Matter. 2008, 4, 2303
41. Xu., J. H.; Li., S. W.; Tostado., C.; Lan., W. J.; Luo., G. S. Preparation of monodispersed chitosan microspheres and in situ encapsulation of BSA in a co-axial microfluidic device Biomed. Microdevices 2009, 11, 243
42. Zhou, C. F.; Yue, P. T.; Feng, J. J. Formation of simple and compound drops in microfluidic devices Phys. Fluids. 2006, 18, 092105
43. Nachash, H. J.; Okey, O. Formation and Structure of Polyacrylamide Gels J. Appl. Polym. Sci. 1996, 60, 971
44. Furukawa, H. Effect of varying preparing-concentration on the equilibrium swelling of polyacrylamide gels J. Mol. Struct. 2000, 554, 11
45. Flory, P. J. Principles of Polymer Chemistry; Cornell University Press: New York, 1953; p 195.