Fc-Fc interactions of human IgG4 require dissociation of heavy chains and are formed predominantly by the intra-chain hinge isomer

Molecular Immunology

Volumn 53, Issue 1-2, 2013, Pages 35-42

  Rispens, Theo ^a,b   Meesters, Joyce ^c   den Bleker, Tamara H ^a,b   Ooijevaar De Heer, Pleuni ^a,b   Schuurman, Janine ^c   Parren, Paul W H I ^c   Labrijn, Aran ^c   Aalberse, Rob C ^a,b  

^a SANQUIN RESEARCH   (Netherlands)

^b UNIVERSITY OF AMSTERDAM   (Netherlands)

^c GENMAB   (Netherlands)

Author keywords

Fc interactions; IgG4; IgG4 related disease (IRD); Rheumatoid factor

Indexed keywords

IMMUNOGLOBULIN FC FRAGMENT; IMMUNOGLOBULIN G4; IMMUNOGLOBULIN HEAVY CHAIN;

ARTICLE; CHEMICAL BOND; HUMAN; ISOMER; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; WILD TYPE;

ANIMALS; ELECTROPHORESIS, POLYACRYLAMIDE GEL; HUMANS; IMMUNOGLOBULIN FC FRAGMENTS; IMMUNOGLOBULIN G; IMMUNOGLOBULIN HEAVY CHAINS; MICE;

EID: 84863519925     PISSN: 01615890     EISSN: 18729142     Source Type: Journal    
DOI: 10.1016/j.molimm.2012.06.012     Document Type: Article

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