Is a fully heparin-bonded cardiopulmonary bypass circuit superior to a standard cardiopulmonary bypass circuit?

Interactive Cardiovascular and Thoracic Surgery

Volumn 14, Issue 4, 2012, Pages 406-414

  Mahmood, Sarah ^a   Bilal, Haris ^b   Zaman, Mahvash ^a   Tang, Augustine ^b  

^a UNIVERSITY OF LIVERPOOL   (United Kingdom)

^b BLACKPOOL VICTORIA HOSPITAL   (United Kingdom)

Author keywords

Biocompatible materials; Cardiopulmonary bypass; Heparin; Inflammatory response; Oxidative stress

Indexed keywords

BETA THROMBOGLOBULIN; CYTOKINE; ELASTASE; HEPARIN;

ARTICLE; ARTIFICIAL VENTILATION; BIOCOMPATIBILITY; BLEEDING; BLOOD CLOTTING TIME; BLOOD TRANSFUSION; CARDIOPULMONARY BYPASS; CARDIOPULMONARY BYPASS CIRCUIT; CARDIOVASCULAR EQUIPMENT; COMPLEMENT ACTIVATION; CYTOKINE PRODUCTION; HEALTH CARE COST; HEART SURGERY; HEPARIN BONDED CARDIOPULMONARY BYPASS CIRCUIT; HOSPITALIZATION; HUMAN; INTENSIVE CARE; LENGTH OF STAY; LEUKOCYTE ACTIVATION; LOW DRUG DOSE; PRIORITY JOURNAL; PROGNOSIS; REOPERATION; THROMBOCYTE PRESERVATION;

AGED; ANTICOAGULANTS; BENCHMARKING; CARDIOPULMONARY BYPASS; COATED MATERIALS, BIOCOMPATIBLE; COST-BENEFIT ANALYSIS; EQUIPMENT DESIGN; EVIDENCE-BASED MEDICINE; FEMALE; HEPARIN; HOSPITAL COSTS; HUMANS; LENGTH OF STAY; MALE; MIDDLE AGED; POSTOPERATIVE COMPLICATIONS; TIME FACTORS; TREATMENT OUTCOME;

EID: 84863477484     PISSN: 15699293     EISSN: 15699285     Source Type: Journal    
DOI: 10.1093/icvts/ivr124     Document Type: Article

References (14)

1. Dunning J, Prendergast B, Mackway-Jones K. Towards evidence-based medicine in cardiothoracic surgery: best BETS. Interact CardioVasc Thorac Surg 2003;2:405-9.
2. McCarthy PM, Yared JP, Foster RC, Ogella DA, Borsh JA, Cosgrove DM. A prospective randomized trial of Duraflo II heparin-coated circuits in cardiac reoperations. Ann Thorac Surg 1999;67:1268-73.
3. Jansen PG, te Velthuis H, Huybregts RA, Paulus R, Bulder ER, van der Spoel HI et al. Reduced complement activation and improved postoperative performance after cardiopulmonary bypass with heparincoated circuits. J Thorac CardioVasc Surg 1995;110:829-34.
4. Tayama E, Hayashida N, Akasu K, Kosuga T, Fukunaga S, Akashi H et al. Biocompatibility of heparin-coated extracorporeal bypass circuits: new heparin bonded bioline system. Artif Organs 2000;24:618-23.
5. Fosse E, Thelin S, Svennevig JL, Jansen P, Mollnes TE, Hack E et al. Duraflo II coating of cardiopulmonary bypass circuits reduces complement activation, but does not affect the release of granulocyte enzymes: a European multicentre study. Eur J Cardiothorac Surg 1997;11:320-7.
6. Mangoush O, Purkayastha S, Haj-Yahia S, Kinross J, Hayward M, Bartolozzi F et al. Heparin-bonded circuits versus nonheparin-bonded circuits: an evaluation of their effect on clinical outcomes. Eur J Cardiothorac Surg 2007;31:1058-69.
7. Mirow N, Zittermann A, Koertke H, Maleszka A, Knobl H, Coskun T et al. Heparin-coated extracorporeal circulation in combination with low dose systemic heparinization reduces early postoperative blood loss in cardiac surgery. J CardioVasc Surg 2008;49:277-84.
8. Svenmarker S, Häggmark S, Jansson E, Lindholm R, Appelblad M, Sandström E et al. Use of heparin-bonded circuits in cardiopulmonary bypass improves clinical outcome. Scand Cardiovasc J 2002;36:241-6.
9. Lindholm L, Westerberg M, Bengtsson A, Ekroth R, Jensen E, Jeppsson A. A closed perfusion system with heparin coating and centrifugal pump improves cardiopulmonary bypass biocompatibility in elderly patients. Ann Thorac Surg 2004;78:2131-8.
10. Thiara AS, Andersen VY, Videm V, Mollnes TE, Svennevig K, Hoel TN et al. Comparable biocompatibility of Phisio- and Bioline-coated cardiopulmonary bypass circuits indicated by the inflammatory response. Perfusion 2010;25:9-16.
11. Sohn N, Marcoux J, Mycyk T, Krahn J, Meng Q. The impact of different biocompatible coated cardiopulmonary bypass circuits on inflammatory response and oxidative stress. Perfusion 2009;24:231-7.
12. Eynden VF, Carrier M, Ouellet S, Demers P, Forcillo J, Perrault LP et al. Avecor Trillium oxygenator versus noncoated Monolyth oxygenator: a prospective randomized controlled study. J Card Surg 2008;23:288-93.
13. Hoel TN, Videm V, Baksaas ST, Mollnes TE, Brosstad F, Svennevig JL. Comparison of a Duraflo II-coated cardiopulmonary bypass circuit and a trillium-coated oxygenator during open-heart surgery. Perfusion 2004; 19:177-84.
14. Gunaydin S, McCusker K, Sari T, Onur MA, Zorlutuna Y. Clinical performance and biocompatibility of hyaluronan-based heparin-bonded extracorporeal circuits in different risk cohorts. Interact CardioVasc Thorac Surg 2010;10:371-6.