Orosomucoid serum concentrations and fat depot-specific mRNA and protein expression in humans

Molecules and Cells

Volumn 33, Issue 1, 2012, Pages 35-41

  Alfadda, Assim A ^a,b   Fatma, Sumbul ^a   Chishti, M Azhar ^a,b   Al Naami, Mohammed Y ^a   Elawad, Ruba ^a   Mendoza, Carmen Deanna O ^a   Jo, Hyunsun ^c   Lee, Yun Sok ^d  

^a KING SAUD UNIVERSITY   (Saudi Arabia)

^b KING SAUD UNIVERSITY   (Saudi Arabia)

^c Seoul National University   (South Korea)

^d UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

Author keywords

Adipokines; Obesity; Orosomucoid; Subcutaneous fat; Visceral fat

Indexed keywords

ADIPOCYTOKINE; C REACTIVE PROTEIN; GLUCOSE; GLYCOSYLATED HEMOGLOBIN; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; INSULIN; INTERLEUKIN 6; LEPTIN; LOW DENSITY LIPOPROTEIN CHOLESTEROL; MESSENGER RNA; OROSOMUCOID; TRIACYLGLYCEROL; TUMOR NECROSIS FACTOR ALPHA;

ADOLESCENT; ADULT; AGED; ARTICLE; BLOOD SAMPLING; BODY FAT; BODY FAT DISTRIBUTION; BODY MASS; BODY WEIGHT; CONTROLLED STUDY; CORRELATION ANALYSIS; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; GLUCOSE BLOOD LEVEL; HUMAN; HUMAN TISSUE; INSULIN RESISTANCE; INTRAABDOMINAL FAT; LIPID STORAGE; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; OBESITY; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; SUBCUTANEOUS FAT; TRIACYLGLYCEROL BLOOD LEVEL;

ADIPONECTIN; ADOLESCENT; ADULT; AGED; ANIMALS; C-REACTIVE PROTEIN; FEMALE; HUMANS; INTERLEUKIN-6; LEPTIN; MALE; MICE; MIDDLE AGED; OBESITY; OROSOMUCOID; RNA, MESSENGER; SUBCUTANEOUS FAT; TUMOR NECROSIS FACTOR-ALPHA; YOUNG ADULT;

MUS;

EID: 84863465530     PISSN: 10168478     EISSN: 02191032     Source Type: Journal    
DOI: 10.1007/s10059-012-2181-9     Document Type: Article

References (28)

1. Ahima, R. S., and Flier, J. S. (2000). Adipose tissue as an endocrine organ. Trends Endocrinol. Metab. 11, 327-332.
2. Alberti, K. G., Zimmet, P., and Shaw, J. (2006). Metabolic syndrome-a new world-wide definition. A consensus statement from the international diabetes federation. Diabet. Med. 23, 469-480.
3. Alessi, M. C., Peiretti, F., Morange, P., Henry, M., Nalbone, G., and Juhan-Vague, I. (1997). Production of plasminogen activator inhibitor 1 by human adipose tissue: possible link between visceral fat accumulation and vascular disease. Diabetes 46, 860-867. (Pubitemid 27188265)
4. Benedek, I. H., Fiske, W. D., 3rd, Griffen, W. O., Bell, R. M., Blouin, R. A., and McNamara, P. J. (1983). Serum alpha 1-acid glycoprotein and the binding of drugs in obesity. Br. J. Clin. Pharmacol. 16, 751-754. (Pubitemid 14208224)
5. Benedek, I. H., Blouin, R. A., and McNamara, P. J. (1984). Serum protein binding and the role of increased alpha 1-acid glycoprotein in moderately obese male subjects. Br. J. Clin. Pharmacol. 18, 941-946. (Pubitemid 15190533)
6. Berg, A. H., and Scherer, P. E. (2005). Adipose tissue, inflammation, and cardiovascular disease. Circ. Res. 96, 939-949. (Pubitemid 40712793)
7. Edwards, D. J., Lalka, D., Cerra, F., and Slaughter, R. L. (1982). Alpha1-acid glycoprotein concentration and protein binding in trauma. Clin. Pharmacol. Ther. 31, 62-67. (Pubitemid 12135810)
8. Fisher, F. M., McTernan, P. G., Valsamakis, G., Chetty, R., Harte, A. L., Anwar, A. J., Starcynski, J., Crocker, J., Barnett, A. H., McTernan, C. L., et al. (2002). Differences in adiponectin protein expression: effect of fat depots and type 2 diabetic status. Horm. Metab. Res. 34, 650-654. (Pubitemid 36398701)
9. Fournier, T., Medjoubi, N. N., and Porquet, D. (2000). Alpha-1-acid glycoprotein. Biochim. Biophys. Acta 1482, 157-171.
10. Fried, S. K., Bunkin, D. A., and Greenberg, A. S. (1998). Omental and subcutaneous adipose tissues of obese subjects release interleukin-6: depot difference and regulation by glucocorticoid. J. Clin. Endocrinol. Metab. 83, 847-850. (Pubitemid 28496456)
11. Friedewald, W. T., Levy, R. I., and Fredrickson, D. S. (1972). Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge. Clin. Chem. 18, 499-502.
12. Fukuhara, A., Matsuda, M., Nishizawa, M., Segawa, K., Tanaka, M., Kishimoto, K., Matsuki, Y., Murakami, M., Ichisaka, T., Murakami, H., et al. (2005). Visfatin: a protein secreted by visceral fat that mimics the effects of insulin. Science 307, 426-430. (Pubitemid 40139988)
13. Grundy, S. M., Cleeman, J. I., Daniels, S. R., Donato, K. A., Eckel, R. H., Franklin, B. A., Gordon, D. J., Krauss, R. M., Savage, P. J., Smith, S. C., Jr., et al. (2005). Diagnosis and management of the metabolic syndrome: an American Heart Association/National Heart, Lung, and Blood Institute Scientific Statement. Circulation 112, 2735-2752. (Pubitemid 41532612)
14. Hochepied, T., Berger, F. G., Baumann, H., and Libert, C. (2003). Alpha (1)-acid glycoprotein: an acute phase protein with inflammatory and immunomodulating properties. Cytokine Growth Factor Rev. 14, 25-34. (Pubitemid 36098429)
15. Hotamisligil, G. S. (2006). Inflammation and metabolic disorders. Nature 444, 860-867. (Pubitemid 46024993)
16. Hotamisligil, G. S., Shargill, N. S., and Spiegelman, B. M. (1993). Adipose expression of tumor necrosis factor-alpha: direct role in obesity-linked insulin resistance. Science 259, 87-91. (Pubitemid 23036092)
17. Hotamisligil, G. S., Budavari, A., Murray, D., and Spiegelman, B. M. (1994). Reduced tyrosine kinase activity of the insulin receptor in obesity-diabetes. Central role of tumor necrosis factor-alpha. J. Clin. Invest. 94, 1543-1549.
18. Jackson, P. R., Tucker, G. T., and Woods, H. F. (1982). Altered plasma drug binding in cancer: role of alpha 1-acid glycoprotein and albumin. Clin. Pharmacol. Ther. 32, 295-302. (Pubitemid 13097364)
19. Lee, Y. S., Choi, J. W., Hwang, I., Lee, J. W., Lee, J. H., Kim, A. Y., Huh, J. Y., Koh, Y. J., Koh, G. Y., Son, H. J., et al. (2010). Adipocytokine orosomucoid integrates inflammatory and metabolic signals to preserve energy homeostasis by resolving immoderate inflammation. J. Biol. Chem. 285, 22174-22185.
20. Libert, C., Brouckaert, P., and Fiers, W. (1994). Protection by alpha 1-acid glycoprotein against tumor necrosis factor-induced lethality. J. Exp. Med. 180, 1571-1575.
21. Lin, Y., Rajala, M. W., Berger, J. P., Moller, D. E., Barzilai, N., and Scherer, P. E. (2001). Hyperglycemia-induced production of acute phase reactants in adipose tissue. J. Biol. Chem. 276, 42077-42083.
22. Lusis, A. J. (2000). Atherosclerosis. Nature 407, 233-241.
23. Matthews, D. R., Hosker, J. P., Rudenski, A. S., Naylor, B. A., Treacher, D. F., and Turner, R. C. (1985). Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia 28, 412-419. (Pubitemid 15018832)
24. Montague, C. T., Prins, J. B., Sanders, L., Zhang, J., Sewter, C. P., Digby, J., Byrne, C. D., and O'Rahilly, S. (1998). Depot-related gene expression in human subcutaneous and omental adipocytes. Diabetes 47, 1384-1391. (Pubitemid 28396940)
25. Ouchi, N., Parker, J. L., Lugus, J. J., and Walsh, K. (2011). Adipokines in inflammation and metabolic disease. Nat. Rev. Immunol. 11, 85-97.
26. Piafsky, K. M., Borga, O., Odar-Cederlof, I., Johansson, C., and Sjoqvist, F. (1978). Increased plasma protein binding of propranolol and chlorpromazine mediated by disease-induced elevations of plasma alpha1 acid glycoprotein. N. Engl. J. Med. 299, 1435-1439. (Pubitemid 9192306)
27. Saltevo, J., Laakso, M., Jokelainen, J., Keinanen-Kiukaanniemi, S., Kumpusalo, E., and Vanhala, M. (2008). Levels of adiponectin, C-reactive protein and interleukin-1 receptor antagonist are associated with insulin sensitivity: a population-based study. Diabetes Metab. Res. Rev. 24, 378-383.
28. Stern, N., Osher, E., and Greenman, Y. (2007). Hypoadiponectinemia as a marker of adipocyte dysfunction-part II: the functional significance of low adiponectin secretion. J. Cardiometab. Syndr. 2, 288-294.