Inhibition of therapeutically important polymerases with high affinity bis-intercalators

Bioorganic and Medicinal Chemistry Letters

Volumn 22, Issue 14, 2012, Pages 4844-4848

  Jain, Nitin ^a   Francis, Subhashree ^a   Friedman, Simon H ^a  

^a UNIVERSITY OF MISSOURI KANSAS CITY   (United States)

Author keywords

Intercalators; Library; Reverse transcriptase; Solid phase synthesis; Telomerase

Indexed keywords

2,7 DIMETHYLPROFLAVINE; 7 AMINODACTINOMYCIN; ACRIDINE; ACRIDINE ORANGE; DACTINOMYCIN; DAUNORUBICIN; DOXORUBICIN; ELLIPTICINE; ETHACRIDINE LACTATE; ETHIDIUM BROMIDE; INTERCALATING AGENT; PROPIDIUM IODIDE; RNA DIRECTED DNA POLYMERASE INHIBITOR; TELOMERASE INHIBITOR; UNCLASSIFIED DRUG;

ARTICLE; DRUG ACTIVITY; DRUG SPECIFICITY; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME INHIBITION;

ENZYME INHIBITORS; INTERCALATING AGENTS; MOLECULAR STRUCTURE; REVERSE TRANSCRIPTASE INHIBITORS; RNA-DIRECTED DNA POLYMERASE; STRUCTURE-ACTIVITY RELATIONSHIP; TELOMERASE;

EID: 84863464133     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2012.05.041     Document Type: Article

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