Wilms tumor-1, claudin-1 and ezrin are useful immunohistochemical markers that help to distinguish schwannoma from fibroblastic meningioma

Pathology and Oncology Research

Volumn 18, Issue 2, 2012, Pages 383-389

  Singh, Avninder ^a   Mishra, Ashwani Kumar ^a   Ylaya, Kris ^b   Hewitt, Stephen M ^b   Sharma, Karam Chand ^a   Saxena, Sunita ^a  

^a SAFDARJUNG HOSPITAL   (India)

^b NATIONAL CANCER INSTITUTE   (United States)

Author keywords

Biomarkers; Fibroblastic meningioma; Immunohistochemistry; Schwannoma; Tissue microarray

Indexed keywords

ANTIBODY; CLAUDIN 1; EPITHELIAL MEMBRANE ANTIGEN; EZRIN; PROTEIN S 100; WT1 PROTEIN;

ADOLESCENT; ADULT; AGED; ARTICLE; CANCER CLASSIFICATION; CANCER DIAGNOSIS; CANCER TISSUE; CONTROLLED STUDY; DIFFERENTIAL DIAGNOSIS; FEMALE; FIBROBLASTIC MENINGIOMA; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; MAJOR CLINICAL STUDY; MALE; MENINGIOMA; NEURILEMOMA; PROTEIN EXPRESSION; RECEIVER OPERATING CHARACTERISTIC; RETROSPECTIVE STUDY; SENSITIVITY AND SPECIFICITY; TISSUE MICROARRAY;

ADOLESCENT; ADULT; AGED; CYTOSKELETAL PROTEINS; DIAGNOSIS, DIFFERENTIAL; FEMALE; FOLLOW-UP STUDIES; HUMANS; IMMUNOENZYME TECHNIQUES; MALE; MEMBRANE PROTEINS; MENINGEAL NEOPLASMS; MENINGIOMA; MIDDLE AGED; MUCIN-1; NEOPLASM STAGING; NEURILEMMOMA; PROGNOSIS; RETROSPECTIVE STUDIES; ROC CURVE; S100 PROTEINS; TISSUE ARRAY ANALYSIS; TUMOR MARKERS, BIOLOGICAL; WT1 PROTEINS; YOUNG ADULT;

EID: 84863455203     PISSN: 12194956     EISSN: 15322807     Source Type: Journal    
DOI: 10.1007/s12253-011-9456-x     Document Type: Article

References (28)

1. Louis DN, Scheithauer BW, Budka H, von Deimling A et al (2000) Meningiomas. In: Kleihues P, Cavenee WK (eds) Tumours of the nervous system. IARC, Lyon, pp 176-184
2. Sloof JL (1984) Pathological anatomical findings in the cerebellopontine angle. Adv Otorhinolaryngol 34:89-953
3. Weiss SW, Langloss JM, Enzinger FM (1983) Value of S-100 protein in the diagnosis of soft tissue tumors with particular reference to benign and malignant Schwann cell tumors. Lab Investig 49:299-308
4. Theaker JM, Gatter KC, Esiri MM, Fleming KA (1986) Epithelial membrane antigen and cytokeratin expression by meningiomas: an immunohistological study. J Clin Pathol 39:435-439
5. Meis JM, Ordonez NG, Bruner JM (1986) Meningiomas. An immunohistochemical study of 50 cases. Arch Pathol Lab Med 110:934-937
6. Schnitt SJ, Vogel H (1986) Meningiomas. Diagnostic value of immunoperoxidase staining for epithelial membrane antigen. Am J Surg Pathol 9:640-649
7. Sloan JP, Ormerod MG (1981) Distribution of epithelial membrane antigen in normal and neoplastic tissues and its value on diagnosis on diagnostic tumor pathology. Cancer 47:1786-1795
8. Perentes E, Nakagawa Y, Ross GW et al (1987) Expression of epithelial membrane antigen in perineurial cells and their derivatives. An immunohistochemical study with multiple markers. Acta Neuropathol 75:160-165
9. Winek RR, Scheithauer BW, Wick MR (1989) Meningioma, meningeal hemangiopericytoma (angioblastic meningioma), peripheral hemangiopericytoma, and acoustic schwannoma (1989) a comparative immunohistochemical study. Am J Surg Pathol 13:251-261
10. Artlich A, Schmidt D (1990) Immunohistochemical profile of meningiomas and their histological subtypes. Hum Pathol 21:843-849
11. Perry A, Scheithauer BW, Nascimento AG (1997) The immunophenotypic spectrum of meningeal hemangiopericytoma: a comparison with fibrous meningioma and solitary fibrous tumor of meninges. Am J Surg Pathol 21:1354-1360
12. Carneiro SS, Scheithauer BW, Nascimento AG, Hirose T, Davis DH (1996) Solitary fibrous tumor of the meninges: a lesion distinct from fibrous meningioma. Am J Clin Pathol 106:217-2242
13. Hahn HP, Bundock EA, Hornick JL (2006) Immunohistochemical staining for claudin-1 can help distinguish menigiomas from histologic mimics. Am J Clin Pathol 125:203-208
14. Avninder S, Ylaya K, Hewitt SM (2008) Tissue microarray: a simple technology that has revolutionized research in pathology. J Postgrad Med 54:158-162
15. Lusis EA, Chicoine MR, Perry A (2005) High throughput screening of meningioma biomarkers using a tissue microarray. J Neuro Oncol 73:219-223
16. Sarwat AM, Al-Salam S (2009) Expression of HIF-1, galectin, cox-2 and Wilms tumor-1 protein in multiple schwannomas of the conus medullaris. J Neuro Oncol 92:111-115
17. Lee SB, Huang K, Palmer R, Truong VB, Herzlinger D, Kolquist KA et al (1999) Wilms' tumor suppressor WT1 encodes a transcriptional activator of amphiregulin. Cell 98:663-673
18. Bhattacharjee M, Adesina AM, Goodman C, Powell S (2003) Claudin-1 expression in meningiomas and schwannomas: possible role in differential diagnosis [abstract]. J Neuropathol Exp Neurol 62:581
19. Stemmer-Rachamimov AO, Xu L, Gonzalez-Augusti C et al (1997) Universal absence of merlin, but not other ERM family members in schwannomas. Am J Pathol 151:1649-1654
20. Böhling T, Turunen O, Jääskeläinen J et al (1996) Ezrin expression in stromal cells of capillary hemangioblastoma. An immunohistochemical survey of brain tumors. Am J Pathol 148:367-373
21. Martinez-Glez V, Hernandez-Franco C, Rey JA (2008) Microarray gene expression profiling in meningiomas and schwannnomas. Curr Med Chem 15:826-833
22. Welling DB, Lasak JM, Akhmametyeva A, Ghaheri B, Chang LS (2002) A cDNA microarray analysis of vestibular schwannomas. Otol Neurotol 23:736-748
23. Fine SW, McClain SA, Maomi L (2004) Immunohistochemical staining for calretinin is useful for differentiating schwannomas from neurofibromas. Am J Clin Pathol 122:552-559
24. Perry A, Cai DX, Scheithauer BW, Swanson PE, Lohse CM, Newsham IF et al (2000) Merlin, DAL-1, and progesterone receptor expression in clinicopathologic subsets of meningioma: a correlative immunohistochemical study of 175 cases. J Neuropathol Exp Neurol 59:872-879
25. Roser F, Nakamuara M, Bellinzona M, Rosahl SK, Ostertag H, Samii M (2004) The prognostic value of progesterone receptor status in meningiomas. J Clin Pathol 57:1033-1037
26. Omulecka A, Papierz W, Nawrocka-Kunecka A, Lewy-Trenda I (2006) Immunohistochemical expression of progesterone and estrogen receptors in meningiomas. Folia Neuropathol 44:111-115
27. Jaiswal S, Agrawal V, Jaiswal AK, Pandey R, Mahapatra AK (2009) Expression of estrogen and progesterone receptors in vestibular schwannomas and their clinical significance. J Negat Results Biomed 8:9
28. Dalgorf DM, Roswell C, Bilbao JM, Chen JM (2008) Immunohistochemical investigation of hormone receptors and vascular growth factor concentration in vestibular schwannomas. Skull Base 18:377-384