Immunohistochemical staining for calretinin is useful for differentiating schwannomas from neurofibromas

American Journal of Clinical Pathology

Volumn 122, Issue 4, 2004, Pages 552-559

  Fine, Samson W ^a   McClain, Steve A ^a   Li, Maomi ^a  

^a ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

Author keywords

Calretinin; Neurofibroma; Schwann cells; Schwannoma

Indexed keywords

CALRETININ;

ARTICLE; BENIGN TUMOR; DIFFERENTIAL DIAGNOSIS; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MAJOR CLINICAL STUDY; NEURILEMOMA; NEUROFIBROMA; PATHOGENESIS; PERIPHERAL NERVE TUMOR; PRIORITY JOURNAL; TUMOR CELL; TUMOR DIAGNOSIS;

EID: 4644318371     PISSN: 00029173     EISSN: None     Source Type: Journal    
DOI: 10.1309/AGBGTBRJ4W0BC7LN     Document Type: Article

References (46)

1. Weiss SW, Goldblum JR. Enzinger and Weiss's Soft Tissue Tumors. 4th ed. St Louis, MO: Mosby; 2001:1111.
2. Fisher ER, Vuzevski VD. Cytogenesis of schwannoma (neurilemoma), neurofibroma, dermatofibroma, and dermatofibrosarcoma as revealed by electron microscopy. Am J Clin Pathol. 1968;49:141-154.
3. Ushigome S, Tadakuwa T, Hyuga M, et al. Perineurial cell tumor and the significance of the perineurial cell in neurofibroma. Acta Pathol Jpn. 1986;36:973-987.
4. Weiss SW, Goldblum JR. Enzinger and Weiss's Soft Tissue Tumors. 4th ed. St Louis, MO: Mosby; 2001:1122-1173.
5. Gray MH, Smoller BR, McNutt NS, et al. Immunohistochemical demonstration of factor XIIIa expression in neurofibromas. Arch Dermatol. 1990;126:472-476.
6. Scheithauer BW, Woodruff JM, Erlandson RA. Tumors of the Peripheral Nervous System. Washington, DC: Armed Forces Institute of Pathology; 1999:177-218. Atlas of Tumor Pathology; Third series, Fascicle 24.
7. Scheithauer BW, Woodruff JM, Erlandson RA. Tumors of the Peripheral Nervous System. Washington, DC: Armed Forces Institute of Pathology; 1999:177-218. Atlas of Tumor Pathology; Third series, Fascicle 24.
8. Rogers J, Khan M, Ellis J. Calretinin and other CaBPs in the nervous system. Adv Exp Med Biol. 1990;269:195-203.
9. Andressen C, Blumcke I, Celio MR. Calcium-binding proteins: selective markers of nerve cells. Cell Tissue Res. 1993;271:181-208.
10. Schwaller B, Buchwald P, Blumcke I, et al. Characterization of a polyclonal antiserum against purified human recombinant calcium binding protein calretinin. Cell Calcium. 1993;14:639-648.
11. Fine SW, Li M. Expression of calretinin and the alpha-subunit of inhibin in granular cell tumors. Am J Clin Pathol. 2003;119:259-264.
12. Seo IS, Azarelli B, Warner TF, et al. Multiple visceral and cutaneous granular cell tumors: ultrastructural and immunohistochemical evidence of Schwann cell origin. Cancer. 1984;53:2104-2110.
13. Doglioni C, Dei Tos AP, Laurino L, et al. Calretinin: a novel immunocytochemical marker for mesothelioma. Am J Surg Pathol. 1996;20:1037-1046.
14. Dei Tos AP, Doglioni C. Calretinin: a novel tool for diagnostic immunohistochemistry. Adv Anat Pathol. 1998;5:61-66.
15. Ordonez NG. Role of immunohistochemistry in distinguishing epithelial peritoneal mesotheliomas from peritoneal and ovarian serous carcinomas. Am J Surg Pathol. 1998;22:1203-1214.
16. Bertschy S, Genton CY, Gotzos V. Selective immunocytochemical localisation of calretinin in the human ovary. Histochem Cell Biol. 1998;109:59-66.
17. Cao QJ, Jones JG, Li M. Expression of calretinin in human ovary, testis and ovarian sex cord-stromal tumors. Int J Gynecol Pathol. 2001;20:346-352.
18. McCluggage WG, Maxwell P. Immunohistochemical staining for calretinin is useful in the diagnosis of ovarian sex cord-stromal tumours. Histopathology. 2001;38:403-408.
19. Augusto D, Leteurtre E, De La Taille A, et al. Calretinin: a valuable marker of normal and neoplastic Leydig cells of the testis. Appl Immunohistochem Mol Morphol. 2002;10:159-162.
20. Lugli A, Forster Y, Haas P, et al. Calretinin expression in human normal and neoplastic tissues: a tissue microarray analysis on 5233 tissue samples. Hum Pathol. 2003;34:994-1000.
21. Zhang PJ, Genega EM, Tomaszewski JE, et al. The role of calretinin, inhibin, melan-A, bcl-2, and c-kit in differentiating adrenal cortical and medullary tumors: an immunohistochemical study. Mod Pathol. 2003;16:591-597.
22. Nogales FF, Isaac MA, Hardisson D, et al. Adenomatoid tumors of the uterus: an analysis of 60 cases. Int J Gynecol Pathol. 2002;21:34-40.
23. Weiss SW, Goldblum JR. Enzinger and Weiss's Soft Tissue Tumors. 4th ed. St Louis, MO: Mosby; 2001:1160.
24. Nemeth A, Penneys N, Bernstein H. Fibrous papule: a tumor of fibrohistiocytic cells that contain factor XIIIa. J Am Acad Dermatol. 1988;19:1102-1106.
25. Nemes Z. Factor XIIIa and the classic histiocytic markers in malignant fibrous histiocytoma: a comparative immunohistochemical study. Hum Pathol. 1988;19:822-829.
26. Johnson MD, Glick AD, Davis BW. Immunohistochemical evaluation of Leu-7, myelin basic-protein, S100-protein, glial-fibrillary acidic-protein, and LN3 immunoreactivity in nerve sheath tumors and sarcomas. Arch Pathol Lab Med. 1988;112:155-160.
27. Parentes E, Rubinstein LJ. Immunohistochemical recognition of human nerve sheath tumors by anti-Leu 7 (HNK-1) monoclonal antibody. Acta Neuropathol (Berl). 1985;68:319-324.
28. Clark HB, Minesky JJ, Agrawal D, et al. Myelin basic protein and P2 protein are not immunohistochemical markers for Schwann cell neoplasms. Am J Pathol. 1985;121:96-101.
29. Penneys NS, Mogollon R, Kowalczyk A, et al. A survey of cutaneous neural lesions for the presence of myelin basic protein. Arch Dermatol. 1984;120:210-213.
30. Memoli VA, Brown EF, Gould VE. Glial fibrillary acidic protein (GFAP) immunoreactivity in peripheral nerve sheath tumors. Ultrastruct Pathol. 1984;7:269-275.
31. Hirose T, Tani T, Shimada T, et al. Immunohistochemical demonstration of EMA/Glut1-positive perineurial cells and CD34-positive fibroblastic cells in peripheral nerve sheath tumors. Mod Pathol. 2003;16:293-298.
32. Armin A, Connelly EM, Rowden G. An immunoperoxidase investigation of S-100 protein in granular cell myoblastoma: evidence for Schwann cell derivation. Am J Clin Pathol. 1983;79:37-44.
33. Fisher ER, Wechsler H. Granular cell myoblastoma: a misnomer: electron microscopic and histochemical evidence concerning its Schwann cell derivation and nature (granular cell Schwannoma). Cancer. 1962;15:936-953.
34. Miettinen M, Lehtonen E, Lehtola H, et al. Histogenesis of granular cell tumor: an immunological and ultrastructural study. J Pathol. 1984;142:221-229.
35. Mukai M. Immunohistochemical localization of S-100 protein and peripheral nerve myelin proteins (P2 protein and P0 protein) in granular cell tumors. Am J Pathol. 1983;112:139-146.
36. Isaacson P. Mast cells in benign nerve sheath tumours. J Pathol. 1976;119:193-196.
37. Yang F, Tran TA, Carlson JA, et al. Paraffin section immunophenotype of cutaneous and extracutaneous mast cell disease: comparison to other hematopoietic neoplasms. Am J Surg Pathol. 2000;24:703-709.
38. Natkunam Y, Rouse RV. Utility of paraffin section immunohistochemistry for c-kit (CD117) in the differential diagnosis of systemic mast cell disease involving the bone marrow. Am J Surg Pathol. 2000;24:81-91.
39. Mangini J, Silverman JF, Dabbs DJ, et al. Diagnostic value of calretinin in mast cell lesions of the skin. Int J Surg Pathol. 2000;8:119-122.
40. Edwards SL, Anderson CR, Southwell BR, et al. Distinct preganglionic neurons innervate noradrenaline and adrenaline cells in the cat adrenal medulla. Neuroscience. 1996;70:825-832.
41. Grkovic I, Anderson CR. Calretinin-containing preganglionic nerve terminals in the rat superior cervical ganglion surround neurons projecting to the submandibular salivary gland. Brain Res. 1995;684:127-135.
42. Huerta JJ, Nori S, Llamosas MM, et al. Calretinin immunoreactivity in human sympathetic ganglia. Anat Embryol (Berl). 1996;194:373-378.
43. Papka RE, Collins J, Copelin T, et al. Calretinin-immunoreactive nerves in the uterus, pelvic autonomic ganglia, lumbosacral dorsal root ganglia and lumbosacral spinal cord. Cell Tissue Res. 1999;298:63-74.
44. Yamamoto Y, Atoji Y, Kuramoto H, et al. Calretinin-immunoreactive laminar nerve endings in the laryngeal mucosa of the rat. Cell Tissue Res. 1998;292:613-617.
45. Serra E, Rosenbaum T, Winner U, et al. Schwann cells harbor the somatic NF1 mutation in neurofibromas: evidence of two different Schwann cell subpopulations. Hum Mol Genet. 2000;9:3055-3064.
46. Lasota J, Wasag B, Dansonka-Mieszkowska A, et al. Evaluation of NF2 and NF1 tumor suppressor genes in distinctive gastrointestinal nerve sheath tumors traditionally diagnosed as benign schwannomas: a study of 20 cases. Lab Invest. 2003;83:1361-1371.