Prostaglandin E 2 blocks menadione-induced apoptosis through the Ras/Raf/Erk signaling pathway in promonocytic leukemia cell lines

Molecules and Cells

Volumn 33, Issue 4, 2012, Pages 371-378

  Yeo, Hyun Seok ^b   Shehzad, Adeeb ^a   Lee, Young Sup ^a  

^a Kyungpook National University   (South Korea)

^b LG Chemical Ltd   (South Korea)

Author keywords

Apoptosis; Menadione; Oxidative stress; Prostaglandin

Indexed keywords

6 ISOPROPOXY 9 OXO 2 XANTHENECARBOXYLIC ACID; ACETYLCYSTEINE; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; LAMIN B; MENADIONE; MITOGEN ACTIVATED PROTEIN KINASE; N [2 (4 BROMOCINNAMYLAMINO)ETHYL] 5 ISOQUINOLINESULFONAMIDE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROSTAGLANDIN E RECEPTOR; PROSTAGLANDIN E2; RAF PROTEIN; RAS PROTEIN; ZINC CHLORIDE; 6-ISOPROPOXY-9-OXOXANTHENE-2-CARBOXYLIC ACID; ISOQUINOLINE DERIVATIVE; N (2 (4 BROMOCINNAMYLAMINO)ETHYL) 5 ISOQUINOLINESULFONAMIDE; N-(2-(4-BROMOCINNAMYLAMINO)ETHYL)-5-ISOQUINOLINESULFONAMIDE; PARP1 PROTEIN, HUMAN; PROSTAGLANDIN E RECEPTOR 2; SULFONAMIDE; XANTHONE DERIVATIVE;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CELL PROTECTION; CELL STRAIN HL 60; CELL SURVIVAL; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; HUMAN; HUMAN CELL; LEUKEMIA CELL LINE; MONOCYTIC LEUKEMIA; OXIDATIVE STRESS; PROTEIN DEGRADATION; SIGNAL TRANSDUCTION; CELL TRANSFORMATION; DRUG ANTAGONISM; DRUG EFFECT; GENE EXPRESSION REGULATION; GENETICS; LEUKEMIA; LIPID PEROXIDATION; METABOLISM;

APOPTOSIS; CELL SURVIVAL; CELL TRANSFORMATION, NEOPLASTIC; CYCLIC AMP-DEPENDENT PROTEIN KINASES; DINOPROSTONE; GENE EXPRESSION REGULATION, NEOPLASTIC; HL-60 CELLS; HUMANS; ISOQUINOLINES; LAMIN TYPE B; LEUKEMIA; LIPID PEROXIDATION; OXIDATIVE STRESS; POLY(ADP-RIBOSE) POLYMERASES; RECEPTORS, PROSTAGLANDIN E, EP2 SUBTYPE; SULFONAMIDES; VITAMIN K 3; XANTHONES;

EID: 84863452965     PISSN: 10168478     EISSN: 02191032     Source Type: Journal    
DOI: 10.1007/s10059-012-2293-2     Document Type: Article

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