Iotrochamides A and B, antitrypanosomal compounds from the Australian marine sponge Iotrochota sp.

Bioorganic and Medicinal Chemistry Letters

Volumn 22, Issue 14, 2012, Pages 4873-4876

  Feng, Yunjiang ^a   Davis, Rohan A ^a   Sykes, Melissa L ^a   Avery, Vicky M ^a   Quinn, Ronald J ^a  

^a GRIFFITH UNIVERSITY   (Australia)

Author keywords

Cinnamoyl amino acids; Human African trypanosomiasis; Iotrochamides A and B; Trypanocidal

Indexed keywords

ANTITRYPANOSOMAL AGENT; DICHLOROMETHANE; IOTROCHAMIDE A; IOTROCHAMIDE B; METHANOL; UNCLASSIFIED DRUG;

ANTIPROTOZOAL ACTIVITY; ARTICLE; AUSTRALIA; BIOASSAY; CYTOTOXICITY TEST; DRUG ISOLATION; DRUG PURIFICATION; DRUG STRUCTURE; HUMAN; HUMAN CELL; IOTROCHOTA; MASS SPECTROMETRY; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; SPONGE (PORIFERA); TRYPANOSOMA BRUCEI;

ANIMALS; ANTIMALARIALS; CERAMIDES; HEK293 CELLS; HUMANS; MOLECULAR STRUCTURE; PORIFERA; STRUCTURE-ACTIVITY RELATIONSHIP; TRYPANOSOMA BRUCEI BRUCEI;

IOTROCHOTA; TRYPANOSOMA BRUCEI BRUCEI;

EID: 84863452362     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2012.05.029     Document Type: Article

References (27)

1. World Health Organization, www.who.int/mediacentre/facsheets/fs259/en.
2. B. Bouteille, O. Oukem, S. Bisser, and M. Dumas Fundam. Clin. Pharmacol. 17 2003 171
3. H.P. de Koning, E. Matovu, M.L. Stewart, F. Geiser, R. Brun, P. Maser, L.J.M. Wallace, R.J. Burchmore, J.C.K. Enyaru, M.P. Barrett, R. Kaminsky, and T. Seebeck Eukaryot. Cell 1003 2003 2
4. D.J. Newman, G.M. Cragg, and K.M. Snader J. Nat. Prod. 1022 2003 66
5. E. Kellenberger, A. Hofmann, and R.J. Quinn Nat. Prod. Rep. 28 2011 1483
6. B.M. McArdle, M.R. Campitelli, and R.J. Quinn J. Nat. Prod. 69 2006 14
7. B.M. McArdle, and R.J. Quinn Chembiochem 8 2007 788
8. J.K. Mitchell, D. Pitcher, B.M. McArdle, T. Alnefelt, S. Duffy, V. Avery, and R.J. Quinn Bioorg. Med. Chem. Lett. 17 2007 6521
9. Y.J. Feng, R.A. Davis, M. Sykes, V.M. Avery, D. Camp, and R.J. Quinn J. Nat. Prod. 73 2010 716
10. Y.J. Feng, R.A. Davis, M.L. Sykes, V.M. Avery, D. Camp, and R.J. Quinn Tetrahedron Lett. 51 2010 4847
11. Y.J. Feng, R.A. Davis, M.L. Sykes, V.M. Avery, A.R. Carroll, D. Camp, and R.J. Quinn Tetrahedron Lett. 51 2010 2477
12. R.A. Davis, O. Demirkiran, M.L. Sykes, V.M. Avery, L. Suraweera, G.A. Fechner, and R.J. Quinn Bioorg. Med. Chem. Lett. 20 2010 4057
13. R.A. Davis, S. Duffy, V.M. Avery, D. Camp, J.N.A. Hooper, and R.J. Quinn Tetrahedron Lett. 51 2010 583
14. M.L. Sykes, and V.M. Avery Am. J. Trop. Med. Hyg. 81 2009 665
15. D. Camp, R.A. Davis, M. Campitelli, J. Ebdon, and R.J. Quinn J. Nat. Prod. 75 2012 72
16. M. Bendig, R. Pink, A. Hudson, and M.A. Mouries Nat. Rev. Drug Disc. 4 2005 727
17. R.J. Quinn, A.R. Carroll, N.B. Pham, P. Baron, M.E. Palframan, L. Suraweera, G.K. Pierens, and S. Muresan J. Nat. Prod. 71 2008 464
18. L.A. Mcdonald, J.C. Swersey, C.M. Ireland, A.R. Carroll, J.C. Coll, B.F. Bowden, C.R. Fairchild, and L. Cornell Tetrahedron 51 1995 5237
19. C.J. Henrich, R.W. Robey, K. Takada, H.R. Bokesch, S.E. Bates, S. Shukla, S.V. Ambudkar, J.B. McMahon, and K.R. Gustafson ACS Chem. Biol. 4 2009 637
20. P. Marfey Carlsberg Res. Commun. 49 1984 591
21. K.R. Gustafson, N. Oku, L.K. Cartner, J.A. Wilson, N. Shigematsu, S. Hess, L.K. Pannell, M.R. Boyd, and J.B. McMahon J. Nat. Prod. 67 2004 1407
22. In Dictionary of Natural Products on DVD; Chapman and Hall: 2009; Vol. 18.2.
23. S.Z. Deng, C.L. Tian, D.J. Xiao, and H.M. Wu Chin. J. Chem. 19 2001 362
24. P. Amade, I. Carletti, and B. Banaigs J. Nat. Prod. 63 2000 981
25. G.W. Chan, T. Francis, D.R. Thureen, P.H. Offen, N.J. Pierce, J.W. Westley, R.K. Johnson, and D.J. Faulkner J. Org. Chem. 58 1993 2544
26. M.R. Rao, and D.J. Faulkner J. Nat. Prod. 1064 2004 67
27. S. Yin, C. Cullinane, A.R. Carroll, R.J. Quinn, and R.A. Davis Tetrahedron Lett. 51 2010 3403