Increased serum clearance of oligomannose species present on a human IgG1 molecule

mAbs

Volumn 4, Issue 4, 2012, Pages 509-520

  Alessandri, Leslie ^a   Ouellette, David ^a   Acquah, Aima ^a   Rieser, Mathew ^a   LeBlond, David ^a   Saltarelli, Mary ^a   Radziejewski, Czeslaw ^a   Fujimori, Taro ^a   Correia, Ivan ^a  

^a ABBOTT LABORATORIES   (United States)

Author keywords

Glycan clearance; Glycoprotein; Oligomannose; Oligosaccharides; Pharmacokinetics; Serum clearance

Indexed keywords

2 AMINOBENZAMIDE; GLYCAN; IMMUNOGLOBULIN G1 ANTIBODY; MANNOSE OLIGOSACCHARIDE; MONOCLONAL ANTIBODY; N ACETYLGLUCOSAMINE; SEPHAROSE;

ANALYTIC METHOD; ARTICLE; BLOOD SAMPLING; CONTROLLED STUDY; CROSS LINKING; FUCOSYLATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN TISSUE; LIMIT OF QUANTITATION; PLASMA CLEARANCE; PROBABILITY; PROTEIN PROCESSING;

ANTIBODIES, MONOCLONAL; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; GLUCANS; HUMANS; IMMUNOGLOBULIN FC FRAGMENTS; IMMUNOGLOBULIN G; MANNOSE; METABOLIC CLEARANCE RATE; MOLECULAR STRUCTURE; MONTE CARLO METHOD; OLIGOSACCHARIDES; ORTHO-AMINOBENZOATES; TIME FACTORS;

EID: 84863448337     PISSN: 19420862     EISSN: 19420870     Source Type: Journal    
DOI: 10.4161/mabs.20450     Document Type: Article

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