Surveillance biopsies in children post-kidney transplant

Pediatric Nephrology

Volumn 27, Issue 5, 2012, Pages 753-760

  Birk, Patricia E ^a  

^a CHILDREN S HOSPITAL RESEARCH INSTITUTE OF MANITOBA   (Canada)

Author keywords

Kidney transplantation; Pediatric; Protocol renal allograft biopsies

Indexed keywords

ACUTE GRAFT REJECTION; CHRONIC GRAFT REJECTION; DIAGNOSTIC VALUE; EARLY DIAGNOSIS; FIBROSING ALVEOLITIS; GLOMERULOPATHY; GRAFT RECIPIENT; HEMATURIA; HIGH RISK PATIENT; HISTOPATHOLOGY; HUMAN; KIDNEY ALLOGRAFT REJECTION; KIDNEY BIOPSY; KIDNEY TRANSPLANTATION; MORBIDITY; PATIENT MONITORING; PEDIATRIC SURGERY; POSTOPERATIVE PERIOD; PRIORITY JOURNAL; RENOVASCULAR DISEASE; REVIEW;

ANTIBODIES; BIOPSY; CHILD; GRAFT REJECTION; HUMANS; KIDNEY; KIDNEY TRANSPLANTATION; MONITORING, PHYSIOLOGIC; RISK FACTORS;

EID: 84863443021     PISSN: 0931041X     EISSN: 1432198X     Source Type: Journal    
DOI: 10.1007/s00467-011-1969-8     Document Type: Review

References (61)

1. Wigmore SJ, Forsythe JLR (2003) To biopsy or not to biopsy. Transplantation 76:909-910 (Pubitemid 37186018)
2. Nankivell BJ, Chapman JR (2006) The significance of subclinical rejection and the value of protocol biopsies. Am J Transplant 6:2006-2012 (Pubitemid 44199535)
3. Birk PE, Rush DN (2006) Protocol biopsies should be standard of care for pediatric renal alloallograft recipients! Pediatr Transplantation 10:760-765 (Pubitemid 44536399)
4. Rush D (2002) Pro: Protocol biopsies should be part of the routine management of kidney transplant recipients. Am J Kid Dis 40:671-673
5. Salomon D (2002) Con: Protocol biopsies should be part of the routine management of kidney transplant recipients. Am J Kid Dis 40:674-677
6. Rush D (2006) Protocol transplant biopsies: An underutilized tool in kidney transplantation. J Am Soc Nephrol 1:138-143
7. Wilkinson A (2006) Protocol transplant biopsies: Are they really needed? J Am Soc Nephrol 1:130-137
8. Racusen L (2006) Protocol transplant biopsies in kidney alloallografts: Why and when are they indicated? J Am Soc Nephrol 1:144-147
9. Shapiro R (2006) Protocol biopsies should not (yet) be standard of care for pediatric renal alloallograft recipients. Pediatr Transplantation 10:766-767 (Pubitemid 44536400)
10. Birk PE (2009) What do we need to do to make protocol biopsies standard of care or should we discontinue doing? Pediatr Transplantation 13:797-801
11. Salvatierra O, Singh T, Shifrin R, Conley S, Alexander S, Tanney D, Lemley S, Sarwal M, Mackie F, Alfrey E, Orlandi P, Zarins C, Herfkens R (1998) Successful transplantation of adult-sized kidneys into infants requires maintenance of high aortic blood flow. Transplantation 66:819-823 (Pubitemid 28487451)
12. Bunchman TE, Fryd DS, Sibley RK, Mauer M (1990) Manifestations of renal allograft rejection in small children receiving adult kidneys. Pediatr Nephrol 4:255-258 (Pubitemid 20187005)
13. Birk PE, Stannard KM, Konrad HB, Blydt-Hansen TD, Ogborn MR, Cheang MS, Gartner JG, Gibson IW (2004) Surveillance biopsies are superior to functional studies for the diagnosis of acute and chronic renal alloallograft pathology in children. Pediatr Transplant 8:29-38 (Pubitemid 38139784)
14. Solez K, Colvin RB, Racusen LC, Sis B, Halloran PF, Birk PE, Campbell PM, Cascalho M, Collins AB, Demetris AJ, Drachenberg CB, Gibson IW, Grimm PC, Haas M, Lerut E, Liapis H, Mannon RB, Marcus PB, Mengel M, Mihatsch MJ, Nankivell BJ, Nickeleit V, Papadimitriou JC, Platt JL, Randhawa P, Roberts I, Salinas-Madriga L, Salomon DR, Seron D, Sheaff M, Weening JJ (2007) Banff '05 Meeting Report: Differential diagnosis of chronic allograft injury and elimination of chronic allograft nephropathy ('CAN'). Am J Transplant 7:518-526 (Pubitemid 46376465)
15. Ettenger RB, Blifeld C, Prince H, Gradus DB-E, Cho S, Sekiya N, Salusky I, Fine RN (1987) The pediatric nephrologist's dilemma: Growth after renal transplantation and its interaction with age as a possible immunologic variable. J Pediatr 111:1022-1025 (Pubitemid 18024931)
16. Scornik J, PfaffWW, Howard RJ, Fennell RS III, Ramos E, Peterson JC, Neiberger R (1994) Increased antibody responsiveness to blood transfusions in pediatric patients. Transplantation 58:1361-1365
17. Birk PE, Blydt-Hansen TD, Dart AB, Kaita LM, Proulx C, Taylor G (2007) Low incidence of adverse events in outpatient pediatric protocol renal alloallograft biopsies. Pediatr Transplant 11:196-200 (Pubitemid 46174992)
18. Racusen L, Solez K, Colvin RB, Bonsib SM, Castro MC, Cavallo T, Croker BP, Demetris AJ, Drachenberg CB, Fogo A, Furness P, Gaber LW, Gibson IW, Glotz D, Goldberg J, Grande J, Halloran PF, Hansen HE, Hartley B, Haryry P, Hill CM, Hoffman EO, Hunsicker LG, Lindblad AS, Marcusssen N, Mihatsch MJ, Nadasdy T, Nickerson P, Olsen TS, Papadimitriou JC, Randhawa PS, Rayner DC, Roberts I, Rose S, Rush D, Salinas-Madrigal L, Salomon DR, Sund S, Taskinen E, Trpkov K, Yamaguchi Y (1999) The Banff 97 working classification of kidney transplant pathology. Kidney Int 55:713-723 (Pubitemid 29082898)
19. Lipman ML, Shen Y, Jeffery JR, Gough J, McKenna RM, Grimm PC, Rush DN (1998) Immune-activation gene expression in clinically stable renal allograft biopsies: Molecular evidence for subclinical rejection. Transplantation 66:1673-1681 (Pubitemid 29034990)
20. Furness PN, Philpott CM, Chorbadjian MT, Nicholson ML, Bosmans J-L, Corthouts BL, Bogers JJPM, Schwarz A, Gwinner W, Haller H, Mengel M, Seron D, Moreso F, Canas C (2003) Protocol biopsy of the stable renal transplant: A multicenter study of methods and complication rates. Transplantation 76:969-973 (Pubitemid 37186029)
21. Mengel M, Chapman JR, Cosio FG, Cavaille-Coll MW, Haller H, Halloran PF, Kirk AD, Mihatsch MJ, Nankivell BJ, Racusen LC, Roberts IS, Rush DN, Schwarz A, Seron D, Stegall M, Colvin RB (2007) Protocol biopsies in renal transplantation: Insights into patient management and pathogenesis. Am J Transplant 7:512-517 (Pubitemid 46376459)
22. Wilczek HE (1990) Percutaneous needle biopsy of the renal alloallograft. A clinical safety evaluation of 1129 biopsies. Transplantation 50:790-797
23. Schwarz A, Gwinner W, Hiss M, Radermacher J, Mengel M, Haller H (2005) Safety and adequacy of renal transplant protocol biopsies. Am J Transplant 5:1992-1996 (Pubitemid 41039876)
24. Benfield MR, Herrin J, Feld L, Rose S, Stablein D, Tejani A (1999) Safety of kidney biopsy in pediatric transplantation: A report of the controlled clinical trials in pediatric transplantation trial of induction therapy study group. Transplantation 67:544-547 (Pubitemid 29114216)
25. Vidhun J, Masciandro J, Varich L, Salvatierra O, Sarwal M (2003) Safety and risk stratification of percutaneous biopsies of adultsized renal alloallografts in infant and older pediatric recipients. Transplantation 76:552-557 (Pubitemid 37013262)
26. Rush DN, Henry S, Jeffery JR, Schroeder TJ, Gough J (1994) Histological findings in early routine biopsies of stable renal allloallograft recipients. Transplantation 57:208-211 (Pubitemid 24048586)
27. Rush DN, Jeffery JR, Gough J (1995) Sequential protocol biopsies in renal transplant patients. Transplantation 59:511-514
28. Kuypers DRJ (2008) Immunosuppressive drug therapy and subclinical acute renal alloallograft rejection: Impact and effect. Transplantation 85:S25-S30 (Pubitemid 351521158)
29. Grimm PC, McKenna R, Nickerson P, Russell ME, Gough J, Gospodarek E, Lui B, Jeffery J, Rush DN (1999) Clinical rejection is distinguished from subclinical rejection by increased infiltration by a population of activated macrophages. J Am Soc Nephrol 10:1582-1589 (Pubitemid 29297534)
30. Hoffman SC, Hale DA, Kleiner DE, Mannon RB, Kampen RL, Jacobson LM, Cendales LC, Swanson SJ, Becker BN, Kirk AD (2005) Functionally significant renal allograft rejection is defined by transcriptional criteria. Am J Transplant 5:573-581 (Pubitemid 40313350)
31. Gloor JM, Cohen A, Lager DJ, Grande JP, Fidler ME, Velosa JA, Larson TS, Schwab TR, Griffin MD, Prieto M, Nyberg S, Sterioff S, Kremers WK, Stegall MD (2002) Subclinical rejection in tacrolimus-treated renal transplant recipients. Transplantation 73:1965-1968 (Pubitemid 34701011)
32. Rush D, Arlen D, Boucher A, Busque S, Cockfield SM, Girardin C, Knoll G, Lachance JG, Landsberg D, Shapiro J, Shoker A, Yilmaz S (2007) Lack of benefit of early protocol biopsies in renal transplant patients receiving TAC and MMF: A randomized study. Am J Transplant 7:2538-2545 (Pubitemid 47561621)
33. Hymes LC, Warshaw BL, Hennigar RA, Amaral SG, Greenbaum LA (2009) Prevalence of clinical rejection after surveillance biopsies in pediatric renal transplants: Does early subclinical rejection predispose to subsequent rejection episodes? Pediatr Transplant 13:823-826
34. Kuypers RJ, Meur L, Cantarovich M, Tredger MJ, Tett SE, Cattaneo D, Tonshoff B, Holt DW, Chapman J, van Gelder T (2010) Consensus report on therapeutic drug monitoring of mycophenolic acid in solid organ transplantation. Clin J Am Soc Nephrol 5:341-358
35. Dart AD, Schall A, Gibson IW, Blydt-Hansen TD, Birk PE (2010) Patterns of chronic injury in pediatric renal allografts. Transplantation 89:334-340
36. Shishido S, Asanuma H, Nakai H, Mori Y, Satoh H, Kamimaki I, Hataya H, Ikeda M, Honda M, Hasegawa A (2003) The impact of repeated subclinical acute rejection on the progression of chronic allograft nephropathy. J Am Soc Nephrol 14:1046-1052 (Pubitemid 36359287)
37. Nankivell BJ, Borrows RJ, Fung CL-S, O'Connell PJ, Allen RDM, Chapman JR (2003) The natural history of chronic allograft nephropathy. N Engl J Med 349:2326-2333 (Pubitemid 37509740)
38. Nankivell BJ, Borrows RJ, Fung CL, O'Connell PJ, Allen RD, Chapman JR (2004) Natural history, risk factors and impact of subclinical rejection in kidney transplantation. Transplantation 78:242-249
39. Nankivell BJ, Fenton-Lee CA, Kuypers DR, Allen RD, O'Connell PJ, Chapman JR (2001) Effect of histological damage on longterm kidney transplant outcome. Transplantation 71:515-523 (Pubitemid 32207202)
40. Masin-Spasovska J, Spasovska G, Dzikova S, Petrusevska G, Lekovski L, Ivanovski N, Popov Z (2007) Do we have to treat subclinical rejections in early protocol renal allograft biopsies? Transplant Proc 39:2550-2553 (Pubitemid 47595348)
41. Masin-Spasovska J, Spasovska G, Polenakovic M, Dzikova S, Petrusevska G, Dimova B, Lekovski L, Popov Z, Ivanovski N (2005) Chronic allograft nephropathy (CAN) in early renal protocol biopsies: Does treatment of borderline and subclinical acute rejections prevent development and progression of CAN? Prilozi 26:91-103
42. Ibernon M, Goma M, Moreso F, Fulladosa X, Hueso M, Cruzado JM, Torras J, Bestard O, Grinyo JM, Seron D (2006) Subclinical rejection impairs glomerular adaptation after renal transplantation. Kidney Int 70:557-561 (Pubitemid 44141583)
43. Ishikawa A, Flechner SM, Goldfarb DA, Myles JL, Modlin CS, Boparai N, Papajcik D, Mastroianni B, Novick AC (1999) Quantitative assessment of the first acute rejection as a predictor of renal transplant outcome. Transplantation 68:1318-1324
44. Choi BS, Shin MJ, Shin SJ, Kim YS, Choi YJ, Kim YS, Moon IS, Kim SY, Koh YB, Bang BK, Yang CW (2005) Clinical significance of an early protocol biopsy in living-donor renal transplantation: Ten-year experience at a single center. Am J Transplant 5:1354-1360 (Pubitemid 40839425)
45. Cosio FG, Grande JP, Wadei H, Larson TS, Griffin MD, Stegall MD (2005) Predicting subsequent decline in kidney allograft function from early surveillance biopsies. Am J Transplant 5:2464-2472
46. Moreso F, Ibernon M, Goma M, Carrera M, Fulladosa X, Hueso M, Gil-Vernet S, Cruzado JM, Torras J, Grinyo JM, Seron D (2006) Subclinical rejection associated with chronic allograft nephropathy in protocol biopsies as a risk factor for late graft loss. Am J Transplant 6:747-752 (Pubitemid 43345012)
47. Nickerson P, Jeffery J, Gough J, McKenna R, Grimm P, Cheang M, Rush D (1998) Identification of clinical and histopathologic risk factors for diminished renal function 2 yrs posttransplant. J Am Soc Nephrol 9:482-487 (Pubitemid 28122875)
48. Scholten EM, Rowshani AT, Cremers S, Bemelman FJ, Eikmans M, van Kan E, Mallat MJ, Florquin S, Surachno J, ten Berge IJ, Bajema IM, de Fijter JW (2006) Untreated rejection in 6-month protocol biopsies is not associated with fibrosis in serial biopsies or with loss of allograft function. J Am Soc Nephrol 17:2622-2632 (Pubitemid 44300980)
49. Roberts IS, Reddy S, Russell C, Davies DR, Friend PJ, Handa AI, Morris PJ (2004) Subclinical rejection and borderline changes in early protocol biopsy specimens after renal transplantation. Transplantation 77:1194-1198 (Pubitemid 38580296)
50. Naessens M, Kambham N, Concepcion W, Salvatierra O, Sarwal M (2007) The evolution of nonimmune histological injury and its clinical relevance in adult-sized kidney grafts in pediatric recipients. Am J Transplant 7:2504-2514 (Pubitemid 47561598)
51. Nankivell BJ, Borrows RJ, Fung CL, O'Connell PJ, Chapman JR, Allen RD (2004) Calcineurin inhibitor nephrotoxicity: Longitudinal assessment by protocol histology. Transplantation 78:557-565 (Pubitemid 39097102)
52. Nankivell BJ, Borrows RJ, Fung CL, O'Connell PJ, Allen RD, Chapman J (2004) Evolution and pathophysiology of renaltransplant glomerulosclerosis. Transplantation 78:461-468
53. Sis B, Mengel M, Haas M, Colvin RB, Halloran PF, Racusen LC, Solez K, Baldwin WM 3rd, Bracamonte ER, Broecker V, Cosio F, Demetris AJ, Drachenberg C, Einecke G, Gloor J, Glotz D, Kraus E, Legendre C, Liapis H, Mannon RB, Nankivell BJ, Nickeleit V, Papadimitriou JC, Randhawa P, Regele H, Renaudin K, Rodriguez ER, Seron D, Seshan S, Suthanthiran M, Wasowska BA, Zachary A, Zeevi A (2010) Banff '09 meeting report: Antibody mediated graft deterioration and implementation of Banff working groups. Am J Transplant 10:464-471
54. Smith RN, Kawai BS, Nadaazdin O, Sachs DH, Cosimi AB, Colvin RB (2008) Four stages and lack of stable accommodation in chronic alloantibody-mediated renal allograft rejection Cynomolgus monkeys. Am J Transplant 8:1662-1667
55. Gloor JM, Sethi S, Stegall MD, Park WD, Moore SB, DeGoey S, Griffin MD, Larson TS, Cosio FG (2007) Transplant glomerulopathy: Subclinical incidence and association with alloantibody. Am J Transplant 7:2124-2132 (Pubitemid 47247042)
56. Everly MJ, Everly JJ, Arend LJ, Brailey P, Susskind B, Govil A, Rike A, Roy-Chaudhury P, Mogilishetty G, Alloway RR, Tevar A, Woodle ES (2009) Reducing de novo donor-specific antibody levels during acute rejection diminishes renal allograft loss. Am J Transplant 9:1063-1071
57. Herman J, Lerut E, Van Damme-Lombaerts R, Emonds MP, Van Damme B (2005) Capillary deposition of complement C4d and C3d in pediatric renal allograft biopsies. Transplantation 79:1435-1440 (Pubitemid 40734809)
58. Seron D, Moreso F, Fulladosa X, Hueso M, Carrera M, Grinyo JM (2002) Reliability of chronic allograft nephropathy diagnosis in sequential protocol biopsies. Kidney Int 61:727-733 (Pubitemid 34102616)
59. Brouard S, Renaudin K, Soulillou JP (2011) Revisting the natural history of IF/TA in renal transplantation. Am J Transplant 11:647-649
60. Stegall MD, Park WD, Larson TS, Gloor JM, Cornell LD, Sethi S, Dean PG, Prieto P, Amer H, Textor S, Schwab T, Cosio FG (2011) The histology of solitary renal allografts at 1 and 5 years after transplantation. Am J Transplant 11:698-707
61. Mannon RB, Matas AJ, Grande J, Leduc R, Connett J, Kasiske B, Cecka JM, Gaston RS, Cosio F, Gourishankar S, Halloran PF, Hunsicker L, Rush D (2010) Inflammation in areas of tubular atrophy in kidney allograft biopsies: A potent predictor of allograft failure. Am J Transplant 10:2066-2073