Simultaneous determination of aspirin and its metabolite from human plasma by UPLC-UV detection: Application to pharmacokinetic study

Journal of Liquid Chromatography and Related Technologies

Volumn 34, Issue 19, 2011, Pages 2326-2338

  Ghosh, Chinmoy ^a   Upadhayay, Anita ^a   Singh, Ajay ^a   Bahadur, Saumya ^a   Jain, Priya ^a   Chakraborty, Bhaswat S ^a  

^a Cadila Pharmaceuticals Limited   (India)

Author keywords

Aspirin; Benzoic acid; Bioequivalence protein precipitation; Salicylic acid; UPLC UV

Indexed keywords

ACQUITY; ANALYSIS TIME; ASPIRIN; BENZOIC ACID; BINARY MODES; CALIBRATION FUNCTIONS; HUMAN PLASMAS; IN-VITRO; INTERFERENCE PEAKS; INTERNAL STANDARDS; ISOCRATIC ELUTION; LC-MS/MS; LINEARITY RANGE; PERCHLORIC ACIDS; PHARMACOKINETIC STUDIES; PROTEIN PRECIPITATION; REPRODUCIBILITIES; SALICYLIC ACIDS; SIMULTANEOUS DETERMINATIONS; SIMULTANEOUS MEASUREMENT; SINGLE-DOSE; UPLC-UV; UV DETECTION;

CARBOXYLIC ACIDS; INORGANIC ACIDS; LIQUID CHROMATOGRAPHY;

PLASMA (HUMAN);

ACETYLSALICYLIC ACID; SALICYLIC ACID;

ACCURACY; ARTICLE; BLOOD SAMPLING; CLINICAL ARTICLE; DRUG BLOOD LEVEL; DRUG DETERMINATION; HEMOLYSIS; HUMAN; HUMAN TISSUE; IN VITRO STUDY; MASS SPECTROMETRY; MAXIMUM PLASMA CONCENTRATION; PLASMA CONCENTRATION-TIME CURVE; SENSITIVITY AND SPECIFICITY; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY;

EID: 84863417003     PISSN: 10826076     EISSN: 1520572X     Source Type: Journal    
DOI: 10.1080/10826076.2011.589092     Document Type: Article

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