메뉴 건너뛰기




Volumn 206, Issue 4, 2012, Pages 349.e1-349.e7

Serum levels of the ovarian cancer biomarker HE4 are decreased in pregnancy and increase with age

Author keywords

biomarker; HE4; healthy women; pregnancy

Indexed keywords

HUMAN EPIDIDYMIS PROTEIN 4;

EID: 84863408154     PISSN: 00029378     EISSN: 10976868     Source Type: Journal    
DOI: 10.1016/j.ajog.2011.12.028     Document Type: Article
Times cited : (136)

References (28)
  • 1
    • 0019790278 scopus 로고
    • Reactivity of a monoclonal antibody with human ovarian carcinoma
    • Bast RC Jr, Feeney M, Lazarus H, Nadler LM, Colvin RB, Knapp RC. Reactivity of a monoclonal antibody with human ovarian carcinoma. J Clin Invest 1981;68:1331-7. (Pubitemid 12235035)
    • (1981) Journal of Clinical Investigation , vol.68 , Issue.5 , pp. 1331-1337
    • Bast Jr., R.C.1    Feeney, M.2    Lazarus, H.3
  • 2
    • 0020559574 scopus 로고
    • A radioimmunoassay using a monoclonal antibody to monitor the course of epithelial ovarian cancer
    • Bast RC Jr, Klug TL, St John E, et al. A radioimmunoassay using a monoclonal antibody to monitor the course of epithelial ovarian cancer. N Engl J Med 1983;309:883-7. (Pubitemid 13014028)
    • (1983) New England Journal of Medicine , vol.309 , Issue.15 , pp. 883-887
    • Bast Jr., R.C.1    Klug, T.L.2    St., J.E.3
  • 4
    • 77951736694 scopus 로고    scopus 로고
    • Current state of biomarker development for clinical application in epithelial ovarian cancer
    • Epub ahead of print
    • Moore RG, Maclaughlan S, Bast RC Jr. Current state of biomarker development for clinical application in epithelial ovarian cancer. Gynecol Oncol 2009. Epub ahead of print.
    • (2009) Gynecol Oncol
    • Moore, R.G.1    Maclaughlan, S.2    Bast Jr., R.C.3
  • 6
    • 63149087256 scopus 로고    scopus 로고
    • Sensitivity and specificity of multimodal and ultrasound screening for ovarian cancer, and stage distribution of detected cancers: Results of the prevalence screen of the UK Collaborative Trial of Ovarian Cancer Screening (UKCTOCS)
    • Menon U, Gentry-Maharaj A, Hallett R, et al. Sensitivity and specificity of multimodal and ultrasound screening for ovarian cancer, and stage distribution of detected cancers: results of the prevalence screen of the UK Collaborative Trial of Ovarian Cancer Screening (UKCTOCS). Lancet Oncol 2009;10:327-40.
    • (2009) Lancet Oncol , vol.10 , pp. 327-340
    • Menon, U.1    Gentry-Maharaj, A.2    Hallett, R.3
  • 7
    • 0021705662 scopus 로고
    • CA125 antigen levels in obstetric and gynecologic patients
    • Niloff JM, Knapp RC, Schaetzl E, Reynolds C, Bast RC Jr. CA125 antigen levels in obstetric and gynecologic patients. Obstet Gynecol 1984;64:703-7. (Pubitemid 15205480)
    • (1984) Obstetrics and Gynecology , vol.64 , Issue.5 , pp. 703-707
    • Niloff, J.M.1    Knapp, R.C.2    Schaetzl, E.3
  • 8
    • 0028307673 scopus 로고
    • Serum CA 125 concentrations in patients with benign ovarian tumours
    • DOI 10.1002/jso.2930560204
    • Buamah PK, Skillen AW. Serum CA 125 concentrations in patients with benign ovarian tumours. J Surg Oncol 1994;56:71-4. (Pubitemid 24209462)
    • (1994) Journal of Surgical Oncology , vol.56 , Issue.2 , pp. 71-74
    • Buamah, P.K.1    Skillen, A.W.2
  • 9
    • 0034520756 scopus 로고    scopus 로고
    • Benign conditions associated with raised serum CA-125 concentration
    • Buamah P. Benign conditions associated with raised serum CA-125 concentration. J Surg Oncol 2000;75:264-5.
    • (2000) J Surg Oncol , vol.75 , pp. 264-265
    • Buamah, P.1
  • 12
    • 16844374909 scopus 로고    scopus 로고
    • Human epididymis protein 4 (HE4) is a secreted glycoprotein that is overexpressed by serous and endometrioid ovarian carcinomas
    • DOI 10.1158/0008-5472.CAN-04-3924
    • Drapkin R, von Horsten HH, Lin Y, et al. Human epididymis protein 4 (HE4) is a secreted glycoprotein that is overexpressed by serous and endometrioid ovarian carcinomas. Cancer Res 2005;65:2162-9. (Pubitemid 40490123)
    • (2005) Cancer Research , vol.65 , Issue.6 , pp. 2162-2169
    • Drapkin, R.1    Von Horsten, H.H.2    Lin, Y.3    Mok, S.C.4    Crum, C.P.5    Welch, W.R.6    Hecht, J.L.7
  • 15
    • 64949192073 scopus 로고    scopus 로고
    • Serum HE4 concentration differentiates malignant ovarian tumours from ovarian endometriotic cysts
    • Huhtinen K, Suvitie P, Hiissa J, et al. Serum HE4 concentration differentiates malignant ovarian tumours from ovarian endometriotic cysts. Br J Cancer 2009;100:1315-9.
    • (2009) Br J Cancer , vol.100 , pp. 1315-1319
    • Huhtinen, K.1    Suvitie, P.2    Hiissa, J.3
  • 16
    • 57649088474 scopus 로고    scopus 로고
    • A novel multiple marker bioassay utilizing HE4 and CA125 for the prediction of ovarian cancer in patients with a pelvic mass
    • Moore RG, McMeekin DS, Brown AK, et al. A novel multiple marker bioassay utilizing HE4 and CA125 for the prediction of ovarian cancer in patients with a pelvic mass. Gynecol Oncol 2009;112:40-6.
    • (2009) Gynecol Oncol , vol.112 , pp. 40-46
    • Moore, R.G.1    McMeekin, D.S.2    Brown, A.K.3
  • 17
    • 77951976918 scopus 로고    scopus 로고
    • Serum biomarker panels for the discrimination of benign from malignant cases in patients with an adnexal mass
    • Nolen B, Velikokhatnaya L, Marrangoni A, et al. Serum biomarker panels for the discrimination of benign from malignant cases in patients with an adnexal mass. Gynecol Oncol 2010; 117:440-5.
    • (2010) Gynecol Oncol , vol.117 , pp. 440-445
    • Nolen, B.1    Velikokhatnaya, L.2    Marrangoni, A.3
  • 18
    • 33646886778 scopus 로고    scopus 로고
    • Comprehensive analysis of HE4 expression in normal and malignant human tissues
    • DOI 10.1038/modpathol.3800612, PII 3800612
    • Galgano MT, Hampton GM, Frierson HF Jr. Comprehensive analysis of HE4 expression in normal and malignant human tissues. Mod Pathol 2006;19:847-53. (Pubitemid 43780455)
    • (2006) Modern Pathology , vol.19 , Issue.6 , pp. 847-853
    • Galgano, M.T.1    Hampton, G.M.2    Frierson Jr., H.F.3
  • 21
    • 53349160350 scopus 로고    scopus 로고
    • Effects of personal characteristics on serum CA125, mesothelin, and HE4 levels in healthy postmenopausal women at high-risk for ovarian cancer
    • Lowe KA, Shah C, Wallace E, et al. Effects of personal characteristics on serum CA125, mesothelin, and HE4 levels in healthy postmenopausal women at high-risk for ovarian cancer. Cancer Epidemiol Biomarkers Prev 2008;17:2480-7.
    • (2008) Cancer Epidemiol Biomarkers Prev , vol.17 , pp. 2480-2487
    • Lowe, K.A.1    Shah, C.2    Wallace, E.3
  • 23
    • 39649107714 scopus 로고    scopus 로고
    • Factors influencing serum concentration of CA125 and CA15-3 in Iranian healthy postmenopausal women
    • Dehaghani AS, Ghiam AF, Hosseini M, Mansouri S, Ghaderi A. Factors influencing serum concentration of CA125 and CA15-3 in Iranian healthy postmenopausal women. Pathol Oncol Res 2007;13:360-4. (Pubitemid 351287319)
    • (2007) Pathology and Oncology Research , vol.13 , Issue.4 , pp. 360-364
    • Dehaghani, A.S.1    Ghiam, A.F.2    Hosseini, M.3    Mansouri, S.4    Ghaderi, A.5
  • 24
    • 0344270007 scopus 로고    scopus 로고
    • Calculation of the risk of ovarian cancer from serial CA-125 values for preclinical detection in postmenopausal women
    • Skates SJ, Menon U, MacDonald N, et al. Calculation of the risk of ovarian cancer from serial CA-125 values for preclinical detection in postmenopausal women. J Clin Oncol 2003;21(suppl):206-10.
    • (2003) J Clin Oncol , vol.21 , Issue.SUPPL. , pp. 206-210
    • Skates, S.J.1    Menon, U.2    MacDonald, N.3
  • 25
  • 28
    • 79961056124 scopus 로고    scopus 로고
    • Evaluation of the diagnostic accuracy of the risk of ovarian malignancy algorithm in women with a pelvic mass
    • Moore RG, Miller MC, Disilvestro P, et al. Evaluation of the diagnostic accuracy of the risk of ovarian malignancy algorithm in women with a pelvic mass. Obstet Gynecol 2011;118:280-8.
    • (2011) Obstet Gynecol , vol.118 , pp. 280-288
    • Moore, R.G.1    Miller, M.C.2    Disilvestro, P.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.